메뉴 건너뛰기




Volumn 18, Issue 11, 1999, Pages 3024-3033

Serum and glucocorticoid-inducible kinase (SGK) is a target of the PI 3-kinase-stimulated signaling pathway

Author keywords

3 phosphoinositide dependent protein kinase 1; Insulin; Phosphoinositide 3 kinase; SGK protein kinase; Signal transduction

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ENZYME INHIBITOR; GLUCOCORTICOID; INSULIN; PERVANADATE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOPROTEIN PHOSPHATASE 2A; PROTEIN KINASE; PROTEIN SERINE THREONINE KINASE; RAPAMYCIN; SERINE; SOMATOMEDIN; THREONINE; WORTMANNIN;

EID: 0033151832     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/18.11.3024     Document Type: Article
Times cited : (492)

References (31)
  • 2
    • 12644301164 scopus 로고    scopus 로고
    • 3-phosphoinositide-dependent protein kinase-1 (PDK1): Structural and functional homology with the Drosophila DSTPK61 kinase
    • Alessi, D.R. et al. (1997a) 3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase. Curr. Biol., 7, 776-789.
    • (1997) Curr. Biol. , vol.7 , pp. 776-789
    • Alessi, D.R.1
  • 3
    • 0031127305 scopus 로고    scopus 로고
    • Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Bα
    • Alessi, D.R., James, S.R., Downes, C.P., Holmes, A.B., Gaffney, P.R., Reese, C.B. and Cohen, P. (1997b) Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Bα. Curr. Biol., 7, 261-269.
    • (1997) Curr. Biol. , vol.7 , pp. 261-269
    • Alessi, D.R.1    James, S.R.2    Downes, C.P.3    Holmes, A.B.4    Gaffney, P.R.5    Reese, C.B.6    Cohen, P.7
  • 4
    • 0032518467 scopus 로고    scopus 로고
    • 3-Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 s6 kinase in vivo and in vitro
    • Alessi, D.R., Kozlowski, M.T., Weng, Q.P., Morrice, N. and Avruch, J. (1998) 3-Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro. Curr. Biol., 8, 69-81.
    • (1998) Curr. Biol. , vol.8 , pp. 69-81
    • Alessi, D.R.1    Kozlowski, M.T.2    Weng, Q.P.3    Morrice, N.4    Avruch, J.5
  • 5
    • 0030781229 scopus 로고    scopus 로고
    • Follicle stimulating hormone-regulated expression of serum/ glucocorticoid-inducible kinase in rat ovarian granulosa cells: A functional role for the sp1 family in promoter activity
    • Alliston, T.N., Maiyar, A.C., Buse, P., Firestone, G.L. and Richards, J.S. (1997) Follicle stimulating hormone-regulated expression of serum/ glucocorticoid-inducible kinase in rat ovarian granulosa cells: A functional role for the Sp1 family in promoter activity. Mol. Endocrinol., 11, 934-949.
    • (1997) Mol. Endocrinol. , vol.11 , pp. 934-949
    • Alliston, T.N.1    Maiyar, A.C.2    Buse, P.3    Firestone, G.L.4    Richards, J.S.5
  • 6
    • 0029942186 scopus 로고    scopus 로고
    • Activation and phosphorylation of a pleckstrin homology domain containing protein kinase (RAC-PK/PKB) promoted by serum and protein phosphatase inhibitors
    • Andjelković, M., Jakubowicz, T., Cron, P., Ming, X.F., Han, J.W. and Hemmings, B.A. (1996) Activation and phosphorylation of a pleckstrin homology domain containing protein kinase (RAC-PK/PKB) promoted by serum and protein phosphatase inhibitors. Proc. Natl Acad. Sci. USA, 93, 5699-5704.
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , pp. 5699-5704
    • Andjelković, M.1    Jakubowicz, T.2    Cron, P.3    Ming, X.F.4    Han, J.W.5    Hemmings, B.A.6
  • 7
    • 0033545393 scopus 로고    scopus 로고
    • PDK1 - A kinase at the hub of things
    • Belham, C., Wu, S. and Avruch, J. (1999) PDK1 - a kinase at the hub of things. Curr. Biol., 9, R93-R96.
    • (1999) Curr. Biol. , vol.9
    • Belham, C.1    Wu, S.2    Avruch, J.3
  • 8
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford, M.M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem., 72, 248-254.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 9
    • 0033548592 scopus 로고    scopus 로고
    • Cell cycle and hormonal control of nuclear-cytoplasmic localization of the serum and glucocorticoid inducible protein kinase, Sgk, in mammary tumor cells: A novel convergence point of anti-proliferative and proliferative cell signaling pathways
    • Buse, P., Tran, S.H., Luther, E., Phu, P.T, Aponte, G.W. and Firestone, G.L. (1999) Cell cycle and hormonal control of nuclear-cytoplasmic localization of the serum and glucocorticoid inducible protein kinase, Sgk, in mammary tumor cells: A novel convergence point of anti-proliferative and proliferative cell signaling pathways. J. Biol. Chem., 274, 7253-7263.
    • (1999) J. Biol. Chem. , vol.274 , pp. 7253-7263
    • Buse, P.1    Tran, S.H.2    Luther, E.3    Phu, P.T.4    Aponte, G.W.5    Firestone, G.L.6
  • 11
    • 0025782827 scopus 로고
    • Inefficient homooligomerization contributes to the dependence of myogenin on E2A products for efficient DNA binding
    • Chakraborty, T., Brennan, J.J., Li, L., Edmondson, D. and Olson, E.N. (1991) Inefficient homooligomerization contributes to the dependence of myogenin on E2A products for efficient DNA binding. Mol. Cell. Biol., 11, 3633-3641.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 3633-3641
    • Chakraborty, T.1    Brennan, J.J.2    Li, L.3    Edmondson, D.4    Olson, E.N.5
  • 12
    • 0023711798 scopus 로고
    • Calcium phosphate-mediated gene transfer: A highly efficient transfection system for stably transforming cells with plasmid DNA
    • Chen, C.A. and Okayama, H. (1988) Calcium phosphate-mediated gene transfer: a highly efficient transfection system for stably transforming cells with plasmid DNA. Biotechniques, 6, 632-638.
    • (1988) Biotechniques , vol.6 , pp. 632-638
    • Chen, C.A.1    Okayama, H.2
  • 14
    • 0032544011 scopus 로고    scopus 로고
    • Phosphorylation and activation of cAMP-dependent protein kinase by phosphoinositide-dependent protein kinase
    • Cheng, X., Ma, Y., Moore, M., Hemmings, B.A. and Taylor, S.S. (1998) Phosphorylation and activation of cAMP-dependent protein kinase by phosphoinositide-dependent protein kinase. Proc. Natl Acad. Sci. USA, 95, 9849-9854.
    • (1998) Proc. Natl Acad. Sci. USA , vol.95 , pp. 9849-9854
    • Cheng, X.1    Ma, Y.2    Moore, M.3    Hemmings, B.A.4    Taylor, S.S.5
  • 16
    • 0029098523 scopus 로고
    • Overexpression of mammalian protein kinase Cζ does not affect the growth characteristics of NIH 3t3 cells
    • Crespo, P., Mischak, H. and Gutkind, J.S. (1995) Overexpression of mammalian protein kinase Cζ does not affect the growth characteristics of NIH 3T3 cells. Biochem. Biophys. Res. Commun., 213, 2266-2272.
    • (1995) Biochem. Biophys. Res. Commun. , vol.213 , pp. 2266-2272
    • Crespo, P.1    Mischak, H.2    Gutkind, J.S.3
  • 17
    • 0030727229 scopus 로고    scopus 로고
    • Heparin suppresses sgk, an early response gene in proliferating vascular smooth muscle cells
    • Delmolino, L.M. and Castellot, J.J., Jr (1997) Heparin suppresses sgk, an early response gene in proliferating vascular smooth muscle cells. J. Cell. Physiol., 73, 371-379.
    • (1997) J. Cell. Physiol. , vol.73 , pp. 371-379
    • Delmolino, L.M.1    Castellot J.J., Jr.2
  • 19
    • 0033018109 scopus 로고    scopus 로고
    • Mechanism of protein kinase B activation by insulin/IGF1 revealed by specific inhibitors of phosphoinositide 3-kinase : Significance for diabetes and cancer
    • in press
    • Galetić, I., Andjelković, M., Meier, R., Brodbeck, D., Park, J. and Hemmings, B.A. (1999) Mechanism of protein kinase B activation by insulin/IGF1 revealed by specific inhibitors of phosphoinositide 3-kinase : significance for diabetes and cancer. Pharmacol. Ther., in press.
    • (1999) Pharmacol. Ther.
    • Galetić, I.1    Andjelković, M.2    Meier, R.3    Brodbeck, D.4    Park, J.5    Hemmings, B.A.6
  • 20
    • 0030738354 scopus 로고    scopus 로고
    • Distribution of the messenger RNA for the extracellularly regulated kinases 1, 2 and 3 in rat brain: Effects of excitotoxic hippocampal lesions
    • Hollister, R.D., Page, K.J. and Hyman, B.T. (1997) Distribution of the messenger RNA for the extracellularly regulated kinases 1, 2 and 3 in rat brain: effects of excitotoxic hippocampal lesions. Neuroscience, 79, 1111-1119.
    • (1997) Neuroscience , vol.79 , pp. 1111-1119
    • Hollister, R.D.1    Page, K.J.2    Hyman, B.T.3
  • 21
    • 0028067836 scopus 로고
    • Differential expression of sgk mRNA, a member of the Ser/Thr protein kinase gene family, in rat brain after CNS injury
    • Imaizumi, K., Tsuda, M., Wanaka, A., Tohyama, M. and Takagi, T. (1994) Differential expression of sgk mRNA, a member of the Ser/Thr protein kinase gene family, in rat brain after CNS injury. Brain Res. Mol. Brain Res., 26, 189-196.
    • (1994) Brain Res. Mol. Brain Res. , vol.26 , pp. 189-196
    • Imaizumi, K.1    Tsuda, M.2    Wanaka, A.3    Tohyama, M.4    Takagi, T.5
  • 22
    • 0032566691 scopus 로고    scopus 로고
    • Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1
    • Le Good, J.A., Ziegler, W.H., Parekh, D.B., Alessi, D.R., Cohen, P. and Parker, P.J. (1998) Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1. Science, 281, 2042-2045.
    • (1998) Science , vol.281 , pp. 2042-2045
    • Le Good, J.A.1    Ziegler, W.H.2    Parekh, D.B.3    Alessi, D.R.4    Cohen, P.5    Parker, P.J.6
  • 23
    • 0028875925 scopus 로고
    • Comparison of the specificities of p70 s6 kinase and MAPKAP kinase-1 identifies a relatively specific substrate for p70 s6 kinase: The N-terminal kinase domain of MAPKAP kinase-1 is essential for peptide phosphorylation
    • Leighton, I.A., Dalby, K.N., Caudwell, F.B., Cohen, P.T.W. and Cohen, P. (1995) Comparison of the specificities of p70 S6 kinase and MAPKAP kinase-1 identifies a relatively specific substrate for p70 S6 kinase: the N-terminal kinase domain of MAPKAP kinase-1 is essential for peptide phosphorylation. FEBS Lett., 375, 289-293.
    • (1995) FEBS Lett. , vol.375 , pp. 289-293
    • Leighton, I.A.1    Dalby, K.N.2    Caudwell, F.B.3    Cohen, P.T.W.4    Cohen, P.5
  • 24
    • 15844382488 scopus 로고    scopus 로고
    • P53 stimulates promoter activity of the sgk serum/glucocorticoid-inducible serine/threonine protein kinase gene in rodent mammary epithelial cells
    • Maiyar, A.C., Huang, A.J., Phu, P.T., Cha, H.H. and Firestone, G.L. (1996) p53 stimulates promoter activity of the sgk serum/glucocorticoid-inducible serine/threonine protein kinase gene in rodent mammary epithelial cells. J. Biol. Chem., 271, 12414-12422.
    • (1996) J. Biol. Chem. , vol.271 , pp. 12414-12422
    • Maiyar, A.C.1    Huang, A.J.2    Phu, P.T.3    Cha, H.H.4    Firestone, G.L.5
  • 25
    • 0031048422 scopus 로고    scopus 로고
    • Repression of glucocorticoid receptor transactivation and DNA binding of a glucocorticoid response element within the serum/glucocorticoid-inducible protein kinase (sgk) gene promoter by the p53 tumor suppressor protein
    • Maiyer, A.C., Phu, P.T., Huang, A.J. and Firestone, G.L. (1997) Repression of glucocorticoid receptor transactivation and DNA binding of a glucocorticoid response element within the serum/glucocorticoid-inducible protein kinase (sgk) gene promoter by the p53 tumor suppressor protein. Mol. Endocrinol., 11, 312-329.
    • (1997) Mol. Endocrinol. , vol.11 , pp. 312-329
    • Maiyer, A.C.1    Phu, P.T.2    Huang, A.J.3    Firestone, G.L.4
  • 26
    • 0028136598 scopus 로고
    • Peroxovanadium compounds. A new class of potent phosphotyrosine phosphatase inhibitors which are insulin mimetics
    • Posner, B.I. et al. (1994) Peroxovanadium compounds. A new class of potent phosphotyrosine phosphatase inhibitors which are insulin mimetics. J. Biol. Chem., 269, 4596-4604.
    • (1994) J. Biol. Chem. , vol.269 , pp. 4596-4604
    • Posner, B.I.1
  • 29
    • 0030999989 scopus 로고    scopus 로고
    • Cloning and characterization of a putative human serine/threonine protein kinase transcriptionally modified during anisotonic and isotonic alterations of cell volume
    • Waldegger, S., Barth, P., Raber, G. and Lang, F. (1997) Cloning and characterization of a putative human serine/threonine protein kinase transcriptionally modified during anisotonic and isotonic alterations of cell volume. Proc. Natl Acad. Sci. USA, 94, 4440-4445.
    • (1997) Proc. Natl Acad. Sci. USA , vol.94 , pp. 4440-4445
    • Waldegger, S.1    Barth, P.2    Raber, G.3    Lang, F.4
  • 30
    • 0027534990 scopus 로고
    • Characterization of sgk, a novel member of the serine/threonine protein kinase gene family which is transcriptionally induced by glucocorticoids and serum
    • Webster, M.K., Goya, L., Ge, Y., Maiyar, A.C. and Firestone, G.L. (1993a) Characterization of sgk, a novel member of the serine/threonine protein kinase gene family which is transcriptionally induced by glucocorticoids and serum. Mol. Cell. Biol., 13, 2031-2040.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 2031-2040
    • Webster, M.K.1    Goya, L.2    Ge, Y.3    Maiyar, A.C.4    Firestone, G.L.5
  • 31
    • 0027195407 scopus 로고
    • Immediate-early transcriptional regulation and rapid mRNA turnover of a putative serine/threonine protein kinase
    • Webster, M.K., Goya, L. and Firestone, G.L. (1993b) Immediate-early transcriptional regulation and rapid mRNA turnover of a putative serine/threonine protein kinase. J. Biol. Chem., 268, 11482-11485.
    • (1993) J. Biol. Chem. , vol.268 , pp. 11482-11485
    • Webster, M.K.1    Goya, L.2    Firestone, G.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.