GITR activation induces an opposite effect on alloreactive CD4+ and CD8+ T cells in graft-versus-host disease

Journal of Experimental Medicine

Volumn 200, Issue 2, 2004, Pages 149-157

  Muriglan, Stephanie J ^a   Ramirez Montagut, Teresa ^a   Alpdogan, Onder ^a   Van Huystee, Thomas W ^a   Eng, Jeffrey M ^a   Hubbard, Vanessa M ^a   Kochman, Adam A ^a   Tjoe, Kartono H ^a   Riccardi, Carlo ^b   Pandolfi, Pier Paolo ^a   Sakaguchi, Shimon ^c,d   Houghton, Alan N ^a   Van Den Brink, Marcel R M ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b UNIVERSITY OF PERUGIA   (Italy)

^c KYOTO UNIVERSITY   (Japan)

^d INST OF PHYS AND CHEMICAL RESEARCH   (Japan)

Author keywords

Immune regulation; In vivo animal models; Lymphocyte activation; T lymphocyte subsets; Transplantation immunology

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; GLUCOCORTICOID; TUMOR NECROSIS FACTOR RECEPTOR;

ALLOIMMUNITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; BONE MARROW TRANSPLANTATION; CELL PROLIFERATION; CONTROLLED STUDY; FEMALE; GENE; GENE EXPRESSION; GRAFT VERSUS HOST REACTION; HISTOCOMPATIBILITY; IMMUNOREGULATION; LYMPHOCYTE ACTIVATION; MACROPHAGE; MORBIDITY; MORTALITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE; UPREGULATION;

ANIMALS; APOPTOSIS; BONE MARROW TRANSPLANTATION; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL DIVISION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; GRAFT VS HOST DISEASE; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; RECEPTORS, INTERLEUKIN-2; RECEPTORS, NERVE GROWTH FACTOR; RECEPTORS, TUMOR NECROSIS FACTOR; UP-REGULATION;

EID: 3242800449     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20040116     Document Type: Article

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