Identification of residues important for agonist recognition and activation in GPR40

Journal of Biological Chemistry

Volumn 282, Issue 40, 2007, Pages 29248-29255

  Chi, Shing Sum ^a   Tikhonova, Irina G ^a   Neumann, Susanne ^a   Engel, Stanislav ^a   Raaka, Bruce M ^a   Costanzi, Stefano ^a   Gershengorn, Marvin C ^a,b  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOGENOUS LIGANDS; FREE FATTY ACIDS (FFA); LINOLEIC ACID; PATHOPHYSIOLOGY;

FATTY ACIDS; INSULIN; LIGANDS; MOLECULAR MODELING; PATHOGENS; PHYSIOLOGICAL MODELS;

ENZYME ACTIVITY;

ARGININE; ASPARAGINE; CARBOXYLIC ACID; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 40; GW 9508; HISTIDINE; LEUCINE; LINOLEIC ACID; STIMULATORY GUANINE NUCLEOTIDE BINDING PROTEIN; TYROSINE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; COMPARATIVE STUDY; CONTROLLED STUDY; HUMAN; HUMAN CELL; HYDROPHILICITY; MOLECULAR MODEL; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTON TRANSPORT;

AMINO ACID SEQUENCE; CELL LINE; CELL MEMBRANE; DOSE-RESPONSE RELATIONSHIP, DRUG; FATTY ACIDS, NONESTERIFIED; HUMANS; LINOLEIC ACID; METHYLAMINES; MODELS, CHEMICAL; MOLECULAR CONFORMATION; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROPIONIC ACIDS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, G-PROTEIN-COUPLED;

EID: 35748937333     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M705077200     Document Type: Article

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