Oleic acid interacts with GPR40 to induce Ca2+ signaling in rat islet β-cells: Mediation by PLC and L-type Ca2+ channel and link to insulin release

American Journal of Physiology - Endocrinology and Metabolism

Volumn 289, Issue 4 52-4, 2005, Pages

  Fujiwara, Ken ^a   Maekawa, Fumihiko ^a   Yada, Toshihiko ^a  

^a JICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

Free fatty acids; G protein coupled receptor; Insulin secretion; Intracellular calcium; Phospholipase C

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL L TYPE; CALCIUM ION; FURA 2; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 40; GLUCOSE; INSULIN; LONG CHAIN FATTY ACID; MESSENGER RNA; NEOMYCIN; NITRENDIPINE; OLEIC ACID; PHOSPHOLIPASE C; PHOSPHOLIPASE C INHIBITOR; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CALCIUM TRANSPORT; CONTROLLED STUDY; CYTOSOL; ENZYME ACTIVITY; ENZYME INHIBITION; FLUORESCENCE; INSULIN RELEASE; INSULINOMA; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

ANIMALS; CALCIUM; CALCIUM CHANNELS, L-TYPE; CALCIUM SIGNALING; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; INSULIN; ISLETS OF LANGERHANS; OLEIC ACID; PHOSPHOLIPASE C; RATS; RATS, WISTAR; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION;

EID: 25144470087     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.00035.2005     Document Type: Article

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