-
1
-
-
0032568920
-
Molecular or pharmacologic perturbation of the link between glucose and lipid metabolism is without effect on glucose-stimulated insulin secretion. A re-evaluation of the long-chain acyl-CoA hypothesis
-
Antinozzi PA, Segall L, Prentki M, McGarry JD, Newgard CB (1998) Molecular or pharmacologic perturbation of the link between glucose and lipid metabolism is without effect on glucose-stimulated insulin secretion. A re-evaluation of the long-chain acyl-CoA hypothesis. J Biol Chem 273:16146-16154
-
(1998)
J Biol Chem
, vol.273
, pp. 16146-16154
-
-
Antinozzi, P.A.1
Segall, L.2
Prentki, M.3
McGarry, J.D.4
Newgard, C.B.5
-
2
-
-
0032030866
-
Chronic exposure to free fatty acid reduces pancreatic beta cell insulin content by increasing basal insulin secretion that is not compensated for by a corresponding increase in proinsulin biosynthesis translation
-
Bollheimer LC, Skelly RH, Chester MW, McGarry JD, Rhodes CJ (1998) Chronic exposure to free fatty acid reduces pancreatic beta cell insulin content by increasing basal insulin secretion that is not compensated for by a corresponding increase in proinsulin biosynthesis translation. J Clin Invest 101:1094-1101
-
(1998)
J Clin Invest
, vol.101
, pp. 1094-1101
-
-
Bollheimer, L.C.1
Skelly, R.H.2
Chester, M.W.3
McGarry, J.D.4
Rhodes, C.J.5
-
3
-
-
0037838892
-
The orphan G protein-coupled receptor GPR40 is activated by medium and long chain fatty acids
-
Briscoe CP, Tadayyon M, Andrews JL, Benson WG, Chambers JK, Eilert MM, Ellis C, Elshourbagy NA, Goetz AS, Minnick DT, Murdock PR, Sauls HR Jr, Shabon U, Spinage LD, Strum JC, Szekeres PG, Tan KB, Way JM, Ignar DM, Wilson S, Muir AI (2003) The orphan G protein-coupled receptor GPR40 is activated by medium and long chain fatty acids. J Biol Chem 278:11303-11311
-
(2003)
J Biol Chem
, vol.278
, pp. 11303-11311
-
-
Briscoe, C.P.1
Tadayyon, M.2
Andrews, J.L.3
Benson, W.G.4
Chambers, J.K.5
Eilert, M.M.6
Ellis, C.7
Elshourbagy, N.A.8
Goetz, A.S.9
Minnick, D.T.10
Murdock, P.R.11
Sauls Jr., H.R.12
Shabon, U.13
Spinage, L.D.14
Strum, J.C.15
Szekeres, P.G.16
Tan, K.B.17
Way, J.M.18
Ignar, D.M.19
Wilson, S.20
Muir, A.I.21
more..
-
4
-
-
0015379202
-
Specific inhibition of mitochondrial fatty acid oxidation by 2-bromopalmitate and its coenzyme A and carnitine esters
-
Chase JF, Tubbs PK (1972) Specific inhibition of mitochondrial fatty acid oxidation by 2-bromopalmitate and its coenzyme A and carnitine esters. Biochem J 129:55-65
-
(1972)
Biochem J
, vol.129
, pp. 55-65
-
-
Chase, J.F.1
Tubbs, P.K.2
-
5
-
-
0028236988
-
More direct evidence for a malonyl-CoA-carnitine palmitoyltransferase I interaction as a key event in pancreatic beta-cell signaling
-
Chen S, Ogawa A, Ohneda M, Unger RH, Foster DW, McGarry JD (1994) More direct evidence for a malonyl-CoA-carnitine palmitoyltransferase I interaction as a key event in pancreatic beta-cell signaling. Diabetes 43:878-883
-
(1994)
Diabetes
, vol.43
, pp. 878-883
-
-
Chen, S.1
Ogawa, A.2
Ohneda, M.3
Unger, R.H.4
Foster, D.W.5
McGarry, J.D.6
-
6
-
-
0033960381
-
The role of long-chain fatty acyl-CoA esters in beta-cell signal transduction
-
Corkey BE, Deeney JT, Yaney GC, Tornheim K, Prentki M (2000) The role of long-chain fatty acyl-CoA esters in beta-cell signal transduction. J Nutr 130:299S-304S
-
(2000)
J Nutr
, vol.130
-
-
Corkey, B.E.1
Deeney, J.T.2
Yaney, G.C.3
Tornheim, K.4
Prentki, M.5
-
7
-
-
0034737731
-
Acute stimulation with long chain acyl-CoA enhances exocytosis in insulin-secreting cells (HIT T-15 and NMRI beta-cells)
-
Deeney JT, Gromada J, Hoy M, Olsen HL, Rhodes CJ, Prentki M, Berggren PO, Corkey BE (2000) Acute stimulation with long chain acyl-CoA enhances exocytosis in insulin-secreting cells (HIT T-15 and NMRI beta-cells) J Biol Chem 275:9363-9368
-
(2000)
J Biol Chem
, vol.275
, pp. 9363-9368
-
-
Deeney, J.T.1
Gromada, J.2
Hoy, M.3
Olsen, H.L.4
Rhodes, C.J.5
Prentki, M.6
Berggren, P.O.7
Corkey, B.E.8
-
8
-
-
0031683543
-
Circulating fatty acids are essential for efficient glucose-stimulated insulin secretion after prolonged fasting in humans
-
Dobbins RL, Chester MW, Daniels MB, McGarry JD, Stein DT (1998a) Circulating fatty acids are essential for efficient glucose-stimulated insulin secretion after prolonged fasting in humans. Diabetes 47:1613-1618
-
(1998)
Diabetes
, vol.47
, pp. 1613-1618
-
-
Dobbins, R.L.1
Chester, M.W.2
Daniels, M.B.3
McGarry, J.D.4
Stein, D.T.5
-
9
-
-
0032102146
-
A fatty acid- dependent step is critically important for both glucose- and non-glucose-stimulated insulin secretion
-
Dobbins RL, Chester MW, Stevenson BE, Daniels MB, Stein DT, McGarry JD (1998b) A fatty acid- dependent step is critically important for both glucose- and non-glucose-stimulated insulin secretion. J Clin Invest 101:2370-2376
-
(1998)
J Clin Invest
, vol.101
, pp. 2370-2376
-
-
Dobbins, R.L.1
Chester, M.W.2
Stevenson, B.E.3
Daniels, M.B.4
Stein, D.T.5
McGarry, J.D.6
-
10
-
-
15444366638
-
Transcriptional regulation of lipid metabolism by fatty acids: A key determinant of pancreatic beta-cell function
-
Lond
-
Fatehi-Hassanabad Z, Chan CB (2005) Transcriptional regulation of lipid metabolism by fatty acids: a key determinant of pancreatic beta-cell function. Nutr Metab (Lond) 2:1
-
(2005)
Nutr Metab
, vol.2
, pp. 1
-
-
Fatehi-Hassanabad, Z.1
Chan, C.B.2
-
11
-
-
3843128644
-
Intracellular trafficking of hormone receptors
-
Gaborik Z, Hunyady L (2004) Intracellular trafficking of hormone receptors. Trends Endocrinol Metab 15:286-293
-
(2004)
Trends Endocrinol Metab
, vol.15
, pp. 286-293
-
-
Gaborik, Z.1
Hunyady, L.2
-
12
-
-
0022408439
-
An improved method for isolation of mouse pancreatic islets
-
Gotoh M, Maki T, Kiyoizumi T, Satomi S, Monaco AP (1985) An improved method for isolation of mouse pancreatic islets. Transplantation 40:437-438
-
(1985)
Transplantation
, vol.40
, pp. 437-438
-
-
Gotoh, M.1
Maki, T.2
Kiyoizumi, T.3
Satomi, S.4
Monaco, A.P.5
-
13
-
-
0037211642
-
Pleiotropic effects of fatty acids on pancreatic beta-cells
-
Haber EP, Ximenes HM, Procopio J, Carvalho CR, Curi R, Carpinelli AR (2003) Pleiotropic effects of fatty acids on pancreatic beta-cells. J Cell Physiol 194:1-12
-
(2003)
J Cell Physiol
, vol.194
, pp. 1-12
-
-
Haber, E.P.1
Ximenes, H.M.2
Procopio, J.3
Carvalho, C.R.4
Curi, R.5
Carpinelli, A.R.6
-
14
-
-
0037086052
-
Morpholino oligos: Making sense of antisense?
-
Heasman J (2002) Morpholino oligos: making sense of antisense? Dev Biol 243:209-214
-
(2002)
Dev Biol
, vol.243
, pp. 209-214
-
-
Heasman, J.1
-
15
-
-
0037434991
-
Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40
-
Itoh Y, Kawamata Y, Harada M, Kobayashi M, Fujii R, Fukusumi S, Ogi K, Hosoya M, Tanaka Y, Uejima H, Tanaka H, Maruyama M, Satoh R, Okubo S, Kizawa H, Komatsu H, Matsumura F, Noguchi Y, Shinohara T, Hinuma S, Fujisawa Y, Fujino M (2003) Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40. Nature 422:173-176
-
(2003)
Nature
, vol.422
, pp. 173-176
-
-
Itoh, Y.1
Kawamata, Y.2
Harada, M.3
Kobayashi, M.4
Fujii, R.5
Fukusumi, S.6
Ogi, K.7
Hosoya, M.8
Tanaka, Y.9
Uejima, H.10
Tanaka, H.11
Maruyama, M.12
Satoh, R.13
Okubo, S.14
Kizawa, H.15
Komatsu, H.16
Matsumura, F.17
Noguchi, Y.18
Shinohara, T.19
Hinuma, S.20
Fujisawa, Y.21
Fujino, M.22
more..
-
16
-
-
0036070769
-
Negative and positive regulatory epitopes in the C-terminal domains of the human B1 and B2 bradykinin receptor subtypes determine receptor coupling efficacy to G(q/11)-mediated [correction of G(9/11)-mediated] phospholipase Cbeta activity
-
Kang DS, Leeb-Lundberg LM (2002) Negative and positive regulatory epitopes in the C-terminal domains of the human B1 and B2 bradykinin receptor subtypes determine receptor coupling efficacy to G(q/11)-mediated [correction of G(9/11)-mediated] phospholipase Cbeta activity. Mol Pharmacol 62:281-288
-
(2002)
Mol Pharmacol
, vol.62
, pp. 281-288
-
-
Kang, D.S.1
Leeb-Lundberg, L.M.2
-
17
-
-
0031434924
-
Differences between natural and recombinant G protein-coupled receptor systems with varying receptor/G protein stoichiometry
-
Kenakin T (1997) Differences between natural and recombinant G protein-coupled receptor systems with varying receptor/G protein stoichiometry. Trends Pharmacol Sci 18:456-464
-
(1997)
Trends Pharmacol Sci
, vol.18
, pp. 456-464
-
-
Kenakin, T.1
-
18
-
-
0037447842
-
Optimized reporter gene assays based on a synthetic multifunctional promoter and a secreted luciferase
-
Kotarsky K, Antonsson L, Owman C, Olde B (2003a) Optimized reporter gene assays based on a synthetic multifunctional promoter and a secreted luciferase. Anal Biochem 316:208-215
-
(2003)
Anal Biochem
, vol.316
, pp. 208-215
-
-
Kotarsky, K.1
Antonsson, L.2
Owman, C.3
Olde, B.4
-
19
-
-
0037423719
-
A human cell surface receptor activated by free fatty acids and thiazolidinedione drugs
-
Kotarsky K, Nilsson NE, Flodgren E, Owman C, Olde B (2003b) A human cell surface receptor activated by free fatty acids and thiazolidinedione drugs. Biochem Biophys Res Commun 301:406-410
-
(2003)
Biochem Biophys Res Commun
, vol.301
, pp. 406-410
-
-
Kotarsky, K.1
Nilsson, N.E.2
Flodgren, E.3
Owman, C.4
Olde, B.5
-
20
-
-
3242793327
-
Historical review: A brief history and personal retrospective of seven-transmembrane receptors
-
Lefkowitz RJ (2004) Historical review: a brief history and personal retrospective of seven-transmembrane receptors. Trends Pharmacol Sci 25:413-422
-
(2004)
Trends Pharmacol Sci
, vol.25
, pp. 413-422
-
-
Lefkowitz, R.J.1
-
21
-
-
0037840616
-
Molecular mechanisms mediating inhibition of G protein-coupled inwardly-rectifying K+ channels
-
Lei Q, Jones MB, Talley EM, Garrison JC, Bayliss DA (2003) Molecular mechanisms mediating inhibition of G protein-coupled inwardly-rectifying K+ channels. Mol Cells 15:1-9
-
(2003)
Mol Cells
, vol.15
, pp. 1-9
-
-
Lei, Q.1
Jones, M.B.2
Talley, E.M.3
Garrison, J.C.4
Bayliss, D.A.5
-
22
-
-
0025281303
-
Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: Special reference to expression of glucose transporter isoforms
-
Miyazaki J, Araki K, Yamato E, Ikegami H, Asano T, Shibasaki Y, Oka Y, Yamamura K (1990) Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms. Endocrinology 127:126-132
-
(1990)
Endocrinology
, vol.127
, pp. 126-132
-
-
Miyazaki, J.1
Araki, K.2
Yamato, E.3
Ikegami, H.4
Asano, T.5
Shibasaki, Y.6
Oka, Y.7
Yamamura, K.8
-
23
-
-
3242670708
-
Palmitate increases L-type Ca2+ currents and the size of the readily releasable granule pool in mouse pancreatic beta-cells
-
Olofsson CS, Salehi A, Holm C, Rorsman P (2004) Palmitate increases L-type Ca2+ currents and the size of the readily releasable granule pool in mouse pancreatic beta-cells. J Physiol 557:935-948
-
(2004)
J Physiol
, vol.557
, pp. 935-948
-
-
Olofsson, C.S.1
Salehi, A.2
Holm, C.3
Rorsman, P.4
-
24
-
-
0242367268
-
Palmitate potentiation of glucose-induced insulin release: A study using 2-bromopalmitate
-
Parker SM, Moore PC, Johnson LM, Poitout V (2003) Palmitate potentiation of glucose-induced insulin release: a study using 2-bromopalmitate. Metabolism 52:1367-1371
-
(2003)
Metabolism
, vol.52
, pp. 1367-1371
-
-
Parker, S.M.1
Moore, P.C.2
Johnson, L.M.3
Poitout, V.4
-
25
-
-
0038607420
-
The ins and outs of fatty acids on the pancreatic beta cell
-
Poitout V (2003) The ins and outs of fatty acids on the pancreatic beta cell. Trends Endocrinol Metab 14:201-203
-
(2003)
Trends Endocrinol Metab
, vol.14
, pp. 201-203
-
-
Poitout, V.1
-
26
-
-
0026733643
-
Malonyl-CoA and long chain acyl-CoA esters as metabolic coupling factors in nutrient-induced insulin secretion
-
Prentki M, Vischer S, Glennon MC, Regazzi R, Deeney JT, Corkey BE (1992) Malonyl-CoA and long chain acyl-CoA esters as metabolic coupling factors in nutrient-induced insulin secretion. J Biol Chem 267:5802-5810
-
(1992)
J Biol Chem
, vol.267
, pp. 5802-5810
-
-
Prentki, M.1
Vischer, S.2
Glennon, M.C.3
Regazzi, R.4
Deeney, J.T.5
Corkey, B.E.6
-
27
-
-
85088179042
-
Sulfonylurea stimulation of insulin secretion
-
Proks P, Reimann F, Green N, Gribble F, Ashcroft F (2002) Sulfonylurea stimulation of insulin secretion. Diabetes Suppl 3
-
(2002)
Diabetes Suppl
, vol.3
-
-
Proks, P.1
Reimann, F.2
Green, N.3
Gribble, F.4
Ashcroft, F.5
-
28
-
-
20244370455
-
Palmitate-induced Ca2+-signaling in pancreatic beta-cells
-
Remizov O, Jakubov R, Dufer M, Krippeit Drews P, Drews G, Waring M, Brabant G, Wienbergen A, Rustenbeck I, Schofl C (2003) Palmitate-induced Ca2+-signaling in pancreatic beta-cells. Mol Cell Endocrinol 212:1-9
-
(2003)
Mol Cell Endocrinol
, vol.212
, pp. 1-9
-
-
Remizov, O.1
Jakubov, R.2
Dufer, M.3
Krippeit Drews, P.4
Drews, G.5
Waring, M.6
Brabant, G.7
Wienbergen, A.8
Rustenbeck, I.9
Schofl, C.10
-
29
-
-
0842284799
-
Beta-cell glucose toxicity, lipotoxicity, and chronic oxidative stress in type 2 diabetes
-
Robertson RP, Harmon J, Tran PO, Poitout V (2004) Beta-cell glucose toxicity, lipotoxicity, and chronic oxidative stress in type 2 diabetes. Diabetes 53(Suppl 1):S119-S124
-
(2004)
Diabetes
, vol.53
, Issue.1 SUPPL.
-
-
Robertson, R.P.1
Harmon, J.2
Tran, P.O.3
Poitout, V.4
-
30
-
-
0035714740
-
Total parenteral nutrition modulates hormone release by stimulating expression and activity of inducible nitric oxide synthase in rat pancreatic islets
-
Salehi A, Ekelund M, Henningsson R, Lundquist I (2001) Total parenteral nutrition modulates hormone release by stimulating expression and activity of inducible nitric oxide synthase in rat pancreatic islets. Endocrine 16:97-104
-
(2001)
Endocrine
, vol.16
, pp. 97-104
-
-
Salehi, A.1
Ekelund, M.2
Henningsson, R.3
Lundquist, I.4
-
31
-
-
0037247680
-
Total parenteral nutrition-stimulated activity of inducible nitric oxide synthase in rat pancreatic islets is suppressed by glucagon-like peptide-1
-
Salehi A, Ekelund M, Lundquist I (2003) Total parenteral nutrition-stimulated activity of inducible nitric oxide synthase in rat pancreatic islets is suppressed by glucagon-like peptide-1. Horm Metab Res 35:48-54
-
(2003)
Horm Metab Res
, vol.35
, pp. 48-54
-
-
Salehi, A.1
Ekelund, M.2
Lundquist, I.3
-
32
-
-
0034964630
-
Functional expression and characterization of a voltage-gated CaV1.3 (alpha1D) calcium channel subunit from an insulin-secreting cell line
-
Scholze A, Plant TD, Dolphin AC, Nurnberg B (2001) Functional expression and characterization of a voltage-gated CaV1.3 (alpha1D) calcium channel subunit from an insulin-secreting cell line. Mol Endocrinol 15:1211-1221
-
(2001)
Mol Endocrinol
, vol.15
, pp. 1211-1221
-
-
Scholze, A.1
Plant, T.D.2
Dolphin, A.C.3
Nurnberg, B.4
-
33
-
-
0035310467
-
Somatostatin activates two types of inwardly rectifying K+ channels in MIN-6 cells
-
Smith PA, Sellers LA, Humphrey PP (2001) Somatostatin activates two types of inwardly rectifying K+ channels in MIN-6 cells. J Physiol 532:127-142
-
(2001)
J Physiol
, vol.532
, pp. 127-142
-
-
Smith, P.A.1
Sellers, L.A.2
Humphrey, P.P.3
-
34
-
-
0015230393
-
Analysis of long-chain free fatty acid binding to bovine serum albumin by determination of stepwise equilibrium constants
-
Spector AA, Fletcher JE, Ashbrook JD (1971) Analysis of long-chain free fatty acid binding to bovine serum albumin by determination of stepwise equilibrium constants. Biochemistry 10:3229-3232
-
(1971)
Biochemistry
, vol.10
, pp. 3229-3232
-
-
Spector, A.A.1
Fletcher, J.E.2
Ashbrook, J.D.3
-
35
-
-
0028221978
-
Mechanisms of the stimulation of insulin release by saturated fatty acids. A study of palmitate effects in mouse beta-cells
-
Warnotte C, Gilon P, Nenquin M, Henquin JC (1994) Mechanisms of the stimulation of insulin release by saturated fatty acids. A study of palmitate effects in mouse beta-cells. Diabetes 43:703-711
-
(1994)
Diabetes
, vol.43
, pp. 703-711
-
-
Warnotte, C.1
Gilon, P.2
Nenquin, M.3
Henquin, J.C.4
-
37
-
-
0034457523
-
Long-chain acyl CoA regulation of protein kinase C and fatty acid potentiation of glucose-stimulated insulin secretion in clonal beta-cells
-
Yaney GC, Korchak HM, Corkey BE (2000) Long-chain acyl CoA regulation of protein kinase C and fatty acid potentiation of glucose-stimulated insulin secretion in clonal beta-cells. Endocrinology 141:1989-1998
-
(2000)
Endocrinology
, vol.141
, pp. 1989-1998
-
-
Yaney, G.C.1
Korchak, H.M.2
Corkey, B.E.3
-
38
-
-
1642456656
-
Existence of GPR40 functioning in a human breast cancer cell line, MCF-7
-
Yonezawa T, Katoh K, Obara Y (2004) Existence of GPR40 functioning in a human breast cancer cell line, MCF-7. Biochem Biophys Res Commun 314:805-809
-
(2004)
Biochem Biophys Res Commun
, vol.314
, pp. 805-809
-
-
Yonezawa, T.1
Katoh, K.2
Obara, Y.3
|