Loss-of-function mutation of the GPR40 gene associates with abnormal stimulated insulin secretion by acting on intracellular calcium mobilization

Journal of Clinical Endocrinology and Metabolism

Volumn 93, Issue 9, 2008, Pages 3541-3550

  Vettor, Roberto ^a   Granzotto, Marnie ^a   De Stefani, Diego ^c   Trevellin, Elisabetta ^a   Rossato, Marco ^a   Farina, Maria Grazia ^b   Milan, Gabriella ^a   Pilon, Catia ^a   Nigro, Angela ^b   Federspil, Giovanni ^a   Vigneri, Riccardo ^b   Vitiello, Libero ^a   Rizzuto, Rosario ^c   Baratta, Roberto ^b   Frittitta, Lucia ^b  

^a UNIVERSITY OF PADOVA   (Italy)

^b UNIVERSITY OF CATANIA   (Italy)

^c UNIVERSITY OF FERRARA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AEQUORIN; C PEPTIDE; CALCIUM; FURA 2 ACETOXYMETHYL ESTER; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 40; GLYCINE; INSULIN; OLEIC ACID; SERINE; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BODY MASS; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CONTROLLED STUDY; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC TRANSFECTION; HELA CELL; HETEROZYGOTE; HUMAN; HUMAN CELL; IN VIVO STUDY; INSULIN BLOOD LEVEL; INSULIN RELEASE; MAJOR CLINICAL STUDY; MALE; METABOLIC DISORDER; OBESITY; ORAL GLUCOSE TOLERANCE TEST; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 51649104136     PISSN: 0021972X     EISSN: 0021972X     Source Type: Journal    
DOI: 10.1210/jc.2007-2680     Document Type: Article

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