Ceramide elevates 12-hydroxyeicosatetraenoic acid levels and upregulates 12-lipoxygenase in rat primary hippocampal cell cultures containing predominantly astrocytes

Neurochemistry International

Volumn 53, Issue 6-8, 2008, Pages 220-229

  Prasad, Vidudala V T S ^a   Nithipatikom, Kassem ^a   Harder, David R ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

12 HETE; 12 Hydroxyeicosatetraenoic acid; 12 Lipoxygenase; Ceramide; Inflammation; Lipoxygenase; ROS; Sphingolipids

Indexed keywords

12 HYDROXYICOSATETRAENOIC ACID; ARACHIDONATE 12 LIPOXYGENASE; CERAMIDE; CYCLOOXYGENASE 2; MESSENGER RNA; PHOSPHOLIPASE A2; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ARTICLE; ASTROCYTE; CELL CULTURE; CONTROLLED STUDY; CYTOSOL; ENZYME ACTIVITY; HIPPOCAMPUS; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; UPREGULATION;

12-HYDROXY-5,8,10,14-EICOSATETRAENOIC ACID; ANIMALS; ANIMALS, NEWBORN; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ARACHIDONATE 12-LIPOXYGENASE; ASTROCYTES; CELLS, CULTURED; CERAMIDES; CYCLOOXYGENASE 2; DOSE-RESPONSE RELATIONSHIP, DRUG; ENCEPHALITIS; HIPPOCAMPUS; OXIDATIVE STRESS; PHOSPHOLIPASES A2; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; TRANSCRIPTION FACTOR CHOP; UP-REGULATION;

RATTUS;

EID: 56349109857     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuint.2008.07.002     Document Type: Article

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