Polychlorinated biphenyls induce arachidonic acid release in human platelets in a tamoxifen sensitive manner via activation of group IVA cytosolic phospholipase A2-α

Biochemical Pharmacology

Volumn 71, Issue 1-2, 2005, Pages 144-155

  Forsell, Pontus K A ^a,b   Olsson, Anders O ^c,e   Andersson, Erik ^a   Nallan, Laxman ^d   Gelb, Michael H ^d  

^a KAROLINSKA INSTITUTE   (Sweden)

^b Biolipox AB   (Sweden)

^c STOCKHOLM UNIVERSITY   (Sweden)

^d UNIVERSITY OF WASHINGTON   (United States)

^e ASTRAZENECA R AND D   (Sweden)

Author keywords

Arachidonic acid; Cyclooxygenase; Lipoxygenase; Phospholipase A2; Platelets; Polychlorinated biphenyls

Indexed keywords

12 HYDROXYICOSATETRAENOIC ACID; ANTIESTROGEN; ARACHIDONIC ACID; CALCIUM; CYTOSOLIC PHOSPHOLIPASE A2 ALPHA; ESTRADIOL; ICOSANOID; NAFOXIDINE; PHOSPHOLIPASE A2; PHOSPHOLIPASE A2 INHIBITOR; POLYCHLORINATED BIPHENYL; PYRROLIDINE DERIVATIVE; TAMOXIFEN; UNCLASSIFIED DRUG;

ARTICLE; CALCIUM CELL LEVEL; DRUG EFFECT; ENZYME ACTIVATION; ENZYME ACTIVITY; GEL MOBILITY SHIFT ASSAY; HUMAN; HUMAN CELL; INCUBATION TIME; NORMAL HUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; THROMBOCYTE; THROMBOCYTE AGGREGATION;

12-HYDROXY-5,8,10,14-EICOSATETRAENOIC ACID; ARACHIDONIC ACID; BLOOD PLATELETS; CALCIUM; CYTOSOL; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME ACTIVATION; FATTY ACIDS, UNSATURATED; HUMANS; PHOSPHOLIPASES A; PHOSPHORYLATION; PLATELET AGGREGATION; POLYCHLORINATED BIPHENYLS; PROTEIN TRANSPORT; TAMOXIFEN;

EID: 28244477429     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2005.10.014     Document Type: Article

References (74)

1. E.A. Dennis Phospholipases The Enzymes 16 1983 307 353
2. 2 enzymes Prostagland Other Lipid Med 68-69 2002 3 58
3. 2 from the human monocytic cell line U937 Proc Natl Acad Sci USA 87 19 1990 7708 7712
4. 2 is a 100-kDa protein in human monoblast U937 cells J Biol Chem 266 8 1991 5268 5272
5. 2alpha as revealed by gene-targeted mice Prostagland Other Lipid Med 68-69 2002 59 69
6. 2 Nature 390 6660 1997 622 625
7. 2 in allergic response and parturition Nature 390 6660 1997 618 622
8. 2 as defined by gene knockouts Biochim Biophys Acta 1488 1-2 2000 139 148
9. 2 J Biol Chem 273 34 1998 21926 21932
10. 2 J Biol Chem 274 13 1999 8823 8831
11. 2-δ induced in psoriatic skin J Biol Chem 279 2004 12890 12897
12. 2 reveals a novel topology and catalytic mechanism Cell 97 3 1999 349 360
13. 2+-dependent translocation domain with homology to PKC and GAP Cell 65 6 1991 1043 1051
14. 2+-independent catalytic domain J Biol Chem 269 27 1994 18239 18249
15. 2 J Biol Chem 273 3 1998 1365 1372
16. 2 J Biol Chem 274 8 1999 5163 5169
17. 2 translocation to internal membranes J Biol Chem 276 32 2001 30150 30160
18. 2 translocation Adv Enzyme Regul 43 2003 229 244
19. 2 binds with high affinity and specificity to phosphatidylinositol 4,5-bisphosphate resulting in dramatic increases in activity J Biol Chem 273 4 1998 2184 2191
20. 2 regulation J Biol Chem 275 26 2000 20146 20156
21. 2 Biochemistry 37 23 1998 8516 8526
22. 2 in regulating arachidonic acid release in macrophages J Biol Chem 273 14 1998 8203 8211
23. 2 by phosphatidylinositol bisphosphate levels J Immunol 164 10 2000 5398 5402
24. 2 C2 domain for interfacial activity J Biol Chem 278 26 2003 23842 23850
25. 2 J Biol Chem 277 26 2002 23838 23846
26. 2 Biochim Biophys Ata 1488 1-2 2000 124 138
27. 2 J Biol Chem 276 43 2001 39653 39660
28. 2 is necessary but not sufficient for arachidonic acid release in P388D(1) macrophages Biochem Biophys Res Com 267 1 2000 145 148
29. 2 J Cell Biol 145 6 1999 1219 1232
30. 2 by MNK1-related protein kinases J Biol Chem 275 48 2000 37542 37551
31. J.D. McKinney, and C.L. Waller Polychlorinated biphenyls as hormonally active structural analogues Environ Health Perspect 102 1994 290 297
32. K. Nesaretnam, R.R. Corcoran, and P. Darbre 3,4,3′,4′,- Tetrachlorobiphenyl acts as an estrogen in vitro and in vivo Mol Endocrinol 10 1996 923 936
33. G.G.J.M. Kuiper, J.G. Lemmen, B. Carlsson, J.C. Corton, S.H. Safe, and P.T. Van der Saag Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor β Endocrinol 139 1998 4252 4263
34. D. Davis, and S. Safe Immunosuppresive activities of polychlorinated biphenyls in C57BL/6N mice: structure-activity relationship as Ah receptor agonist and partial antagonists Toxicology 63 1990 97 111
35. W. Shain, B. Bush, and R. Seegal Neurotoxocity of polychlorinated biphenyls: structure-activity relationship of individual congeners Toxicol Appl Pharmacol 111 1991 33 42
36. B. Lake, M. Collins, R. Harris, and S. Gangolli The induction of hepatic and extrahepatic xenobiotic metabolism in the rat and ferret by a polychlorinated biphenyl mixture (Aroclor 1254) Xenobiotica 9 12 1979 723 731
37. P. Grandjean, and P. Weihe Arachidonic acid status during pregnancy is associated with polychlorinated biphenyl exposure Am J Clinical Nutrition 77 3 2003 715 719
38. 2 is involved in the mechanism of activation of neutrophils by polychlorinated biphenyls Environ Health Perspect 104 1996 52 58
39. 2 regulate the release of arachidonic acid for eicosanoid production and superoxide anion generation in neutrophils J Immunol 160 2 1998 953 960
40. 2 enzymes J Pharmacol Exp Therapeutic 289 2 1999 1112 1120
41. 2+ influx by 2,2′,4,6-tetrachlorobiphenyl in PC12 cells Toxicol Appl Pharmacol 178 1 2002 37 43
42. 2 by organochlorine compounds Chem Res Toxicol 15 2 2002 153 159
43. P.R.S. Kodavanti, and E.C. Derr-Yellin Differential effects of polybrominated diphenyl ethers and polychlorinated biphenyls on [3H] arachidonic acid release in rat cerebellar granule neurons Toxicol Sci 68 2 2002 451 457
44. 2+/calmodulin during activation of rat neutrophils by polychlorinated biphenyls Biochem Pharmacol 62 8 2001 1125 1132
45. P.R.S. Kodavanti, and H.A. Tilson Structure-activity relationships of potentially neurotoxic PCB congeners in the rat Neurotoxicology 18 1997 425 441
46. 2 by the polychlorinated biphenyl mixture Aroclor 1242 Toxicol Appl Pharmacol 163 1 2000 9 16
47. 2 by organochlorine compounds Toxicol Sci 53 1 2000 40 47
48. 2alpha blocks arachidonic acid release in a variety of mammalian cells Biochim Biophys Acta 1513 2 2001 160 166
49. 2 J Med Chem 43 6 2000 1041 1044
50. G. Sundström Polychlorinated biphenyls II. Synthesis of some tetra- and pentachlorobiphenyls Acta Chem Scand 27 1973 600 624
51. 14C-labeled and unlabeled coplanar polychlorinated biphenyls Acta Chem Scand 44 1990 1071 1076
52. D.E. Schultz, G. Petrick, and J. Duinker Complete characterization of polychlorinated biphenyl congeners in commercial Aroclor and Clophen mixtures by multidimensional gas chromatography-electron capture detection Environ Sci Technol 23 1989 852 859
53. 2 (88 kDa) in immature and mature myeloid cells and its role in leukotriene synthesis in human granulocytes FEBS Lett 434 3 1998 295 299
54. 2, blocks production of arachidonate and 12-hydroxyeicosatetraenoic acid by calcium ionophore-challenged platelets J Biol Chem 269 22 1994 15619 15624
55. 2 is phosphorylated in collagen- and thrombin-stimulated human platelets independent of protein kinase C and mitogen-activated protein kinase J Biol Chem 270 43 1995 25885 25892
56. 2 by bromoenol lactone and trifluoromethyl ketones J Biol Chem 270 1 1995 445 450
57. 2 J Biol Chem 266 11 1991 7227 7232
58. 2 Biochemistry 32 23 1993 5935 5940
59. 2 inhibit release of free arachidonate in thrombin-stimulated human platelets J Biol Chem 269 22 1994 15625 15630
60. 2 prevents arachidonic acid incorporation and phospholipid remodeling in P388D1 macrophages Proc Natl Acad Sci USA 92 1995 8527 8531
61. 2 is phosphorylated in collagen- and thrombin-stimulated human platelets independent of protein kinase c and mitogen-activated protein kinase J Biol Chem 270 43 1995 25885 25892
62. J.D. Croxtall, Q. Choudhury, J.O. White, and R.J. Flower Tamoxifen inhibits the release of arachidonic acid stimulated by thapsigargin in estrogen receptor-negative A549 cells Biochim Biophys Acta 1349 3 1997 275 284
63. 2 activation J Leuko Biol 65 3 1999 330 336
64. D. Deykin, F.A. Russell, and R. Vaillancourt The use of high pressure liquid chromatography (HPLC) for the separation of radiolabeled arachidonic acid and its metabolites produced by thrombin-treated human platelets Prostaglandins 18 1979 19 27
65. P.W. Wong, W.R. Brackney, and I.N. Pessah Ortho-substituted polychlorinated biphenyls alter microsomal calcium transport by direct interaction with ryanodine receptors of mammalian brain J Biol Chem 272 24 1997 15145 15153
66. 2 in rat renal tubular cell cultures in response to PCBs Cell Signal 13 2001 111 118
67. L. Moro, S. Reineri, D. Piranda, D. Pietrapiana, P. Lova, and A. Bertoni Nongenomic effects of 17beta-estradiol in human platelets: potentiation of thrombin-induced aggregation through estrogen receptor beta and Src kinase Blood 105 2005 115 121
68. M. Jayachandran, and V.M. Miller Human platelets contain estrogen receptor alpha, caveolin-1 and estrogen receptor associated proteins Platelets 14 2003 75 81
69. W.C. Chang, J. Nakao, T. Neichi, H. Orimo, and S. Murota Effects of estradiol on the metabolism of arachidonic acid by aortas and platelets in rats Reprod Toxicol 7 1993 237 248
70. J. Matthews, T. Celius, R. Halgren, and T. Zacharewski Differential estrogen receptor binding of estrogenic substances: a species comparison Toxicol Sci 53 2000 326 339
71. K. Nesaretnam, and P. Darbre 3,5,3′,5′-Tetrachlorobiphenyl is a weak oestrogen agonist in vitro and in vivo J Steroid Biochem 62 1997 409 418
72. R.L. Sutherland, L.C. Murphy, M. San Foo, M.D. Green, and A.M. Whybourne High-affinity anti-oestrogen binding site distinct from the oestrogen receptor Nature 288 1980 273 275
73. R. Natarajan, and J. Nadler Role of lipoxygenases in breast cancer Front Biosci 3 1998 E81 E88
74. B. Liu, R.J. Maher, J.P. De Jonckheere, R.U. Popat, S. Stojakovic, and Y.A. Hannun 12(S)-HETE increases the motility of prostate tumor cells through selective activation of PKC alpha Adv Exp Med Biol 400B 1997 707 718