12-Lipoxygenase plays a key role in cell death caused by glutathione depletion and arachidonic acid in rat oligodendrocytes

European Journal of Neuroscience

Volumn 20, Issue 8, 2004, Pages 2049-2058

  Wang, Hong ^a   Li, Jianrong ^a   Follett, Pamela L ^a   Zhang, Yumin ^a   Cotanche, Douglas A ^b   Jensen, Frances E ^a   Volpe, Joseph J ^a   Rosenberg, Paul A ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

12 lipoxygenase; Arachidonic acid; Cell death; Glutathione; Oligodendrocyte; Oxidative stress

Indexed keywords

ARACHIDONATE 12 LIPOXYGENASE; ARACHIDONIC ACID; CYSTEINE; DOCEBENONE; GLUTATHIONE; INDOMETACIN; LIPOXYGENASE INHIBITOR; N BENZYL N HYDROXY 5 PHENYLPENTAMIDE; PROSTAGLANDIN SYNTHASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL DEATH; CONTROLLED STUDY; ENCEPHALOMALACIA; ENZYME ACTIVATION; ENZYME MECHANISM; NERVE CELL DIFFERENTIATION; NEUROTOXICITY; NONHUMAN; OLIGODENDROGLIA; OXIDATIVE STRESS; PATHOGENESIS; PRIORITY JOURNAL; RAT; WHITE MATTER;

ANIMALS; ARACHIDONATE 12-LIPOXYGENASE; ARACHIDONIC ACID; CELL DEATH; CELL SURVIVAL; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUTATHIONE; LIPOXYGENASE INHIBITORS; OLIGODENDROGLIA; RATS; RATS, SPRAGUE-DAWLEY;

EID: 4944264699     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2004.03650.x     Document Type: Article

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