12-Hydroxyeicosatetrenoate (12-HETE) attenuates AMPA receptor-mediated neurotoxicity: Evidence for a G-protein-coupled HETE receptor

Journal of Neuroscience

Volumn 22, Issue 1, 2002, Pages 257-264

  Hampson, Aidan J ^a,c   Grimaldi, Maurizio ^b,d  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^b NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^c Cortex Pharmaceuticals ^*  (United States)

^d UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

Author keywords

AMPA; Eicosanoid; Excitotoxicity; G protein; Glutamate; HETE; Hydroxyeicosatetraenoic acid; Ischemia; Lipoxygenase; VSCCs

Indexed keywords

12 HYDROXYICOSATETRAENOIC ACID; ADENYLATE CYCLASE; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; AMPA RECEPTOR; ARACHIDONIC ACID; CALCIUM CHANNEL L TYPE; CALCIUM CHANNEL N TYPE; EXCITOTOXIN; G PROTEIN COUPLED RECEPTOR; GLUTAMIC ACID; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE TRIPHOSPHATE; ICOSANOID; LIPOXYGENASE; PERTUSSIS TOXIN; POTASSIUM CHANNEL;

ANIMAL CELL; ARTICLE; BRAIN CELL; BRAIN ISCHEMIA; CALCIUM TRANSPORT; CHIRALITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; FETUS; NEUROMODULATION; NEUROTOXICITY; NEUROTRANSMITTER RELEASE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; RAT; STEREOCHEMISTRY;

EID: 0036137948     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.22-01-00257.2002     Document Type: Article

References (49)

1. Glutamate toxicity in neuron-enriched and neuron-astrocyte co-cultures: Effect of the glutamate uptake inhibitor L-trans-pyrrolidine-2,4-dicarboxylate
2. Neuroprotective interaction effects of NMDA and AMPA receptor antagonists in an in vitro model of cerebral ischemia
3. Ischemic brain edema following occlusion of the middle cerebral artery in the rat, II. Alteration of the eicosanoid synthesis profile of brain microvessels
4. Ischemic preconditioning and brain tolerance: Temporal histological and functional outcomes, protein synthesis requirement, and interleukin-1 receptor antagonist and early gene expression
5. Is pharmacological neuroprotection dependent on reduced glutamate release?
6. Interactions of presynaptic Ca2+ channels and snare proteins in neurotransmitter release
7. Bidirectional modulation of AMPA receptor properties by exogenous phospholipase A2 in the hippocampus
8. Lipoxygenase metabolism of arachidonic acid in ischemic preconditioning and PKC-induced protection in heart
9. Pharmacology of glutamate neurotoxicity in cortical cell culture: Attenuation by NMDA antagonists
10. Metabotropic glutamate receptor modulation of excitotoxicity in the neostriatum: Role of calcium channels
11. AMPA receptor activation is rapidly toxic to cortical astrocytes when desensitization is blocked
12. A quick and simple method for the quantitation of lactate dehydrogenase release in measurements of cellular cytotoxicity and tumor necrosis factor (TNF) activity
13. NMDA receptors activate the arachidonic acid cascade system in striatal neurons
14. Therapeutic potential of ischaemic preconditioning
15. Role of calcium channel subtypes in calcium transients in hippocampal CA3 neurons
16. Increased plasma PGE2, 6-keto-PGF1 alpha, and 12-HETE levels following experimental concussive brain injury
17. Mitochondria in neurodegeneration: Acute ischemia and chronic neurodegenerative diseases
18. 12-Lipoxygenase products attenuate the glutamate release and Ca2+ accumulation evoked by depolarization of hippocampal mossy fiber nerve endings
19. Free fatty acids in the rat brain in moderate and severe hypoxia
20. Ionic requirements for neurotoxic effects of excitatory amino acid analogues in rat cerebellar slices
21. Functional and molecular diversity of PACAP/VIP receptors in cortical neurons and type I astrocytes
22. A new generation of Ca2+ indicators with greatly improved fluorescence properties
23. Dual effects of anandamide on NMDA receptor-mediated responses and neurotransmission
24. Selective neuron loss after cerebral ischemia in the rat: Possible role of transmitter glutamate
25. Receptor-mediated modulation of voltage-dependent Ca2+ channels via heterotrimeric G-proteins in neurons
26. Preconditioning in vivo ischemia inhibits anoxic long-term potentiation and functionally protects CA1 neurons in the gerbil
27. L-type voltage-gated calcium channels modulate kainic acid neurotoxicity in cerebellar granule cells
28. Actions of general anaesthetics and arachidonic pathway inhibitors on K+ currents activated by volatile anaesthetics and FMRF amide in molluscan neurones
29. Calcium homeostasis, nimodipine and stroke
30. Presynaptic regulation of glutamate release in the ventral tegmental area during morphine withdrawal
31. Isolation and identification of lipoxygenase products from the rat central nervous system
32. Role of lipoxygenase metabolites in ischemic preconditioning
33. Localization of arachidonate 12-lipoxygenase in canine brain tissues
34. Arachidonate 12-lipoxygenase is localized in neurons, glial cells, and endothelial cells of the canine brain
35. Involvement of the 12-lipoxygenase pathway of arachidonic acid metabolism in homosynaptic long-term depression of the rat hippocampus
36. Relationship between extracellular glutamate concentration and voltage-sensitive calcium channel function in focal cerebral ischemia in the rat
37. An improved colorimetric assay for cell proliferation and viability utilizing the tetrazolium salt XTT
38. Lipid-dependent modulation of Ca2+ availability in isolated mossy fiber nerve endings
39. Calcicludine, a venom peptide of the Kunitz-type protease inhibitor family, is a potent blocker of high-threshold Ca2+ channels with a high affinity for L-type channels in cerebellar granule neurons
40. Direct opening of S-type K+ channels of Aplysia sensory neurons by 12-lipoxygenase metabolites
41. Ca2+-Zn2+ permeable AMPA or kainate receptors: Possible key factors in selective neurodegeneration
42. Formation of 12-lipoxygenase metabolites in rat cerebral cortical slices: Stimulation by calcium ionophore, glutamate and N-methyl-D-aspartate
43. Mammalian arachidonate 12-lipoxygenases
44. The preconditioning phenomenon: A tool for the scientist or a clinical reality?
45. A second leukotriene B(4) receptor, BLT2. A new therapeutic target in inflammation and immunological disorders
46. Hydroxyeicosanoids bind to and activate the low affinity leukotriene B4 receptor, BLT2
47. Roles of arachidonic acid, lipoxygenases and phosphatases in calcium-dependent modulation of M-current in bullfrog sympathetic neurons
48. The priming effect of 12(S)-hydroxyeicosatetraenoic acid on lymphocyte phospholipase D involves specific binding sites
49. Modulation of voltage-dependent calcium channels by G proteins