Diabetes alters sphingolipid metabolism in the retina: A potential mechanism of cell death in diabetic retinopathy

Diabetes

Volumn 55, Issue 12, 2006, Pages 3573-3580

  Fox, Todd E ^a   Han, Xianlin ^b   Kelly, Samuel ^c   Merrill Jr , Alfred H ^c   Martin, Rex E ^d   Anderson, Robert E ^d   Gardner, Thomas W ^a   Kester, Mark ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^d UNIVERSITY OF OKLAHOMA HEALTH SCIENCES CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CERAMIDE; CERAMIDE GLUCOSYLTRANSFERASE; CERAMIDE GLUCOSYLTRANSFERASE INHIBITOR; GLUCOSAMINE; GLUCOSE; GLUCOSYLCERAMIDE; INSULIN; INTERLEUKIN 1BETA; S6 KINASE; SPHINGOLIPID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DEATH; CONTROLLED STUDY; DIABETES MELLITUS; DIABETIC RETINOPATHY; ELECTROSPRAY MASS SPECTROMETRY; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; GLUCOSE BLOOD LEVEL; INSULIN SENSITIVITY; INSULIN TREATMENT; LIPID METABOLISM; LIPOGENESIS; MALE; NONHUMAN; PATHOGENESIS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RETINA; RETINA NERVE CELL; STREPTOZOCIN DIABETES; TANDEM MASS SPECTROMETRY;

ANIMALS; CELL DEATH; CELL LINE; CELL SURVIVAL; CERAMIDES; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC RETINOPATHY; GLUCOSYLTRANSFERASES; GLYCOSPHINGOLIPIDS; MALE; RATS; RATS, SPRAGUE-DAWLEY; REFERENCE VALUES; RETINA; SPHINGOLIPIDS;

EID: 33845547166     PISSN: 00121797     EISSN: 00121797     Source Type: Journal    
DOI: 10.2337/db06-0539     Document Type: Article

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