12-Lipoxygenase Metabolites of Arachidonic Acid Mediate Metabotropic Glutamate Receptor-Dependent Long-Term Depression at Hippocampal CA3-CA1 Synapses

Journal of Neuroscience

Volumn 23, Issue 36, 2003, Pages 11427-11435

  Feinmark, Steven J ^a   Begum, Roxana ^a   Tsvetkov, Evgeny ^c   Goussakov, Ivan ^c   Funk, Colin D ^b   Siegelbaum, Steven A ^a   Bolshakov, Vadim Y ^c  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

12 Lipoxygenase; Arachidonic acid; Hippocampus; LTD; Metabotropic glutamate receptors; Retrograde messenger; Synaptic transmission

Indexed keywords

12 HYDROXYICOSATETRAENOIC ACID; ARACHIDONATE 12 LIPOXYGENASE; ARACHIDONIC ACID; METABOTROPIC RECEPTOR;

ANIMAL TISSUE; ARACHIDONIC ACID METABOLISM; ARTICLE; ENZYME INHIBITION; HIPPOCAMPUS; HOMOLOGOUS RECOMBINATION; LONG TERM DEPRESSION; LONG TERM POTENTIATION; MOUSE; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SYNAPTIC TRANSMISSION;

EID: 0346218111     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.23-36-11427.2003     Document Type: Article

References (43)

1. Bolshakov VY, Siegelbaum SA (1994) Postsynaptic induction and presynaptic expression of hippocampal long-term depression. Science 264:1148-1152.
2. Bolshakov VY, Siegelbaum SA (1995) Hippocampal long-term depression: arachidonic acid as a potential retrograde messenger. Neuropharmacology 34:1581-1587.
3. Bolshakov VY, Carboni L, Cobb M, Siegelbaum SA, Belardetti F (2000) Dual MAP kinase pathways mediate opposing forms of long-term plasticity at CA3-CA1 synapses. Nat Neurosci 3:1107-1113.
4. 2 by 38-kDa mitogen-activated protein kinase in collagen-stimulated human platelets. Eur J Biochem 245:751-759.
5. + channels by a 12-lipoxygenase metabolite of arachidonic acid. Nature 342:553-555.
6. Cowan WM, Sudhof TC, Stevens CF (2001) Synapses. Baltimore: Johns Hopkins UP.
7. Chen XS, Kurre U, Jenkins NA, Copeland NG, Funk CD cDNA cloning, expression, mutagenesis of C-terminalisoleucine, genomic structure, and chromosomal localizations of murine 12-lipoxygenases (1994) J Biol Chem 269:13979-13987.
8. Cho H, Ueda M, Tamaoka M, Hamaguchi M, Aisaka K, Kiso YH, Inoue T, Ogino R, Tatsuoka T, Ishihara T, Noguchi T, Morita I, Murota S (1991) Novel caffeic acid derivatives: extremely potent inhibitors of 12-lipoxygenase. J Med Chem 34:1503-1505.
9. Drapeau C, Pellerin L, Wolfe LS, Avoli M (1990) Long-term changes of synaptic transmission induced by arachidonic acid in the CA1 subfield of the rat hippocampus. Neurosci Lett 115:286-292.
10. Dudek SM, Bear MF (1992) Homosynaptic long-term depression in area CA1 of hippocampus and effects of N-methyl-D-aspartate receptor blockade. Proc Natl Acad Sci USA 89:4363-4367.
11. Fitzjohn SM, Kingston AE, Lodge D, Collingridge GL (1999) DHPG-induced LTD in area CA1 of juvenile rat hippocampus; characterization and sensitivity to novel mGluR antagonists. Neuropharmacology 38:1577-1583.
12. Fitzsimonds RM, Poo MM (1998) Retrograde signaling in the development and modification of synapses. Physiol Rev 78:143-170.
13. 2+ accumulation evoked by depolarization of hippocampal mossy fiber nerve endings. J Neurochem 56:1079-1082.
14. Gasparini F, Lingenhohl K, Stoehr N, Flor PJ, Heinrich M, Vranesic I, Biollaz M, Allgeier H, Heckendorn R, Urwyler S, Varney MA, Johnson EC, Hess SD, Rao SP, Sacaan AI, Santori EM, Velicelebi G, Kuhn R (1999) 2-Methyl-6-(phenylethynyl)-pyridine (MPEP), a potent, selective and systemically active mGlu5 receptor antagonist. Neuropharmacology 38:1493-1503.
15. Hervieu GJ, Cluderay JE, Gray CW, Green PJ, Ranson JL, Randall AD, Meadows HJ (2001) Distribution and expression of TREK-1, a two-pore-domain potassium channel, in the adult rat CNS. Neuroscience 103:899-919.
16. Hii CS, Huang ZH, Bilney A, Costabile M, Murray AW, Rathjen DA, Der CJ, Ferrante A (1998) Stimulation of p38 phosphorylation and activity by arachidonic acid in HeLa cells, HL60 promyelocytic leukemic cells, and human neutrophils. Evidence for cell type-specific activation of mitogen-activated protein kinases. J Biol Chem 273:19277-19282.
17. 2 in vascular smooth muscle cells. J Pharmacol Exp Ther 304:761-772.
18. 2 messenger RNA mainly in neurons in the rat brain. Neuroscience 92:1061-1077.
19. Lujan R, Nusser Z, Roberts JD, Shigemoto R, Somogyi P (1996) Perisynaptic localization of metabotropic glutamate receptors mGluR1 and mGluR5 on dendrites and dendritic spines in the rat hippocampus. Eur J Neurosci 8:1488-1500.
20. Manzoni OJ, Williams JT (1999) Presynaptic regulation of glutamate release in the ventral tegmental area during morphine withdrawal. J Neurosci 19:6629-6636.
21. Medhurst AD, Rennie G, Chapman CG, Meadows H, Duckworth MD, Kelsell RE, Gloger II, Pangalos MN (2001) Distribution analysis of human two pore domain potassium channels in tissues of the central nervous system and periphery. Brain Res Mol Brain Res 86:101-114.
22. Mulkey RM, Malenka RC (1992) Mechanisms underlying induction of homosynaptic long-term depression in area CA1 of the hippocampus. Neuron 9:967-975.
23. Normandin M, Gagné J, Bernard I, Élie R, Miceli D, Baudry M, Massicotte G (1996) Involvement of the 12-lipoxygenase pathway of arachidonic acid metabolism in homosynaptic long-term depression of the rat hippocampus. Brain Res 730:40-46.
24. O'Dell TJ, Hawkins RD, Kandel ER, Arancio O (1991) Tests of the roles of two diffusible substances in long-term potentiation: evidence for nitric oxide as a possible early retrograde messenger. Proc Natl Acad Sci USA 88:11285-11289.
25. Oliet SH, Malenka RC, Nicoll RA (1997) Two distinct forms of long-term depression coexist in CA1 hippocampal pyramidal cells. Neuron 18:969-982.
26. + channels. Curr Opin Cell Biol 13:422-428.
27. Pin JP, Duvoisin R (1995) The metabotropic glutamate receptors: structure and functions. Neuropharmacology 34:1-26.
28. Piomelli D, Shapiro E, Feinmark SJ, Schwartz JH (1987a) Metabolites of arachidonic acid in the nervous system of Aplysia: possible mediators of synaptic modulation. J Neurosci 7:3675-3686.
29. Piomelli D, Volterra A, Dale N, Siegelbaum SA, Kandel ER, Schwartz JH, Belardetti F (1987b) Lipoxygenase metabolites of arachidonic acid as second messengers for presynaptic inhibition of Aplysia sensory cells. Nature 328:38-43.
30. Rouach N, Nicoll RA (2003) Endocannabinoids contribute to short-term but not long-term mGluR-induced depression in the hippocampus. Eur J Neurosci 18:1017-1020.
31. Rush AM, Wu J, Rowan MJ, Anwyl R (2002) Group I metabotropic glutamate receptor (mGluR)-dependent long-term depression mediated via p38 mitogen-activated protein kinase is inhibited by previous high-frequency stimulation and activation of mGluRs and protein kinase C in the rat dentate gyrus in vitro. J Neurosci 22:6121-6128.
32. Sanes JR, Lichtman JW (1999) Can molecules explain long-term potentiation?. Nat Neurosci 2:597-604.
33. 2 activation is not required for long-term synaptic depression. Eur J Pharmacol 273:R7-9.
34. Steel DJ, Tieman TL, Schwartz JH, Feinmark SJ (1997) Identification of an 8-lipoxygenase pathway in nervous tissue of Aplysia californica. J Biol Chem 272:18673-18681.
35. Sun D, Funk CD (1996) Disruption of 12/15-Lipoxygenase expression in peritoneal macrophages. J Biol Chem 271:24055-24062.
36. Talley EM, Solorzano G, Lei Q, Kim D, Bayliss DA (2001) CNS distribution of members of the two-pore-domain (KCNK) potassium channel family. J Neurosci 21:7491-7505.
37. Watanabe AM, Carlisle HJ, O'Dell TJ (2002) Postsynaptic induction and presynaptic expression of group I mGluR-dependent LTD in the hippocampal CA1 region. J Neurophysiol 87:1395-1403.
38. Watanabe T, Medina JF, Haeggstrom JZ, Rådmark O, Samuelsson B (1993) Molecular cloning of a 12-lipoxygenase cDNA from rat brain. Eur J Biochem 212:605-612.
39. Williams JH, Errington ML, Lynch MA, Bliss TVP (1989) Arachidonic acid induces a long-term activity-dependent enhancement of synaptic transmission in the hippocampus. Nature 341:739-742.
40. 2 from cytosol to membranes in rat brain induced by calcium ions. Biochem Biophys Res Commun 170:484-490.
41. Zakharenko SS, Zablow L, Siegelbaum SA (2002) Altered presynaptic vesicle release and cycling during mGluR-dependent LTD. Neuron 35:1099-1110.
42. Zhu JJ, Qin Y, Zhao M, Van Aelst L, Malinow R (2002) Ras and Rap control AMPA receptor trafficking during synaptic plasticity. Cell 110:443-455.
43. Zink MH, Oltman CL, Lu T, Katakam PV, Kaduce TL, Lee H, Dellsperger KC, Spector AA, Myers PR, Weintraub NL (2001) 12-lipoxygenase in porcine coronary microcirculation: implications for coronary vasoregulation. Am J Physiol 280:H693-H704.