메뉴 건너뛰기




Volumn 26, Issue 10, 2008, Pages 1125-1133

What would you do if you could sequence everything?

Author keywords

[No Author keywords available]

Indexed keywords

ACID RESISTANCE; NUCLEIC ACIDS; THROUGHPUT;

EID: 53649101617     PISSN: 10870156     EISSN: 15461696     Source Type: Journal    
DOI: 10.1038/nbt1494     Document Type: Review
Times cited : (149)

References (112)
  • 1
    • 33750953227 scopus 로고    scopus 로고
    • Whole-genome re-sequencing
    • Bentley, D.R. Whole-genome re-sequencing. Curr. Opin. Genet. Dev. 16, 545-552 (2006).
    • (2006) Curr. Opin. Genet. Dev , vol.16 , pp. 545-552
    • Bentley, D.R.1
  • 2
    • 47249146817 scopus 로고    scopus 로고
    • Genomes for all
    • Church, G.M. Genomes for all. Sci. Am. 294, 46-54 (2006).
    • (2006) Sci. Am , vol.294 , pp. 46-54
    • Church, G.M.1
  • 3
    • 38049138721 scopus 로고    scopus 로고
    • Physical approaches to DNA sequencing and detection
    • Zwolak, M. & DiVentra, M. Physical approaches to DNA sequencing and detection. Rev. Mod. Phys. 80, 141-165 (2008).
    • (2008) Rev. Mod. Phys , vol.80 , pp. 141-165
    • Zwolak, M.1    DiVentra, M.2
  • 4
    • 39649117755 scopus 로고    scopus 로고
    • The impact of next-generation sequencing technology on genetics
    • Mardis, E.R. The impact of next-generation sequencing technology on genetics. Trends Genet. 24, 133-141 (2008).
    • (2008) Trends Genet , vol.24 , pp. 133-141
    • Mardis, E.R.1
  • 5
    • 41749104588 scopus 로고    scopus 로고
    • Single-Molecule DNA Sequencing of a Viral Genome
    • Harris, T.D. et al. Single-Molecule DNA Sequencing of a Viral Genome. Science 320, 106-109 (2008).
    • (2008) Science , vol.320 , pp. 106-109
    • Harris, T.D.1
  • 6
    • 2042437650 scopus 로고    scopus 로고
    • Initial sequencing and analysis of the human genome
    • International Human Genome Sequencing Consortium
    • International Human Genome Sequencing Consortium. Initial sequencing and analysis of the human genome. Nature 409, 860-921 (2001).
    • (2001) Nature , vol.409 , pp. 860-921
  • 7
    • 47149117454 scopus 로고    scopus 로고
    • Drosophila 12 Genomes Consortium. Evolution of genes and genomes on the Drosophila phylogeny
    • Drosophila 12 Genomes Consortium. Evolution of genes and genomes on the Drosophila phylogeny. Nature 450, 203-218 (2007).
    • (2007) Nature , vol.450 , pp. 203-218
  • 8
    • 38749149152 scopus 로고    scopus 로고
    • Whole-genome sequencing and variant discovery in C. elegans
    • Hillier, L.W. et al. Whole-genome sequencing and variant discovery in C. elegans. Nat. Methods 5, 183-188 (2008).
    • (2008) Nat. Methods , vol.5 , pp. 183-188
    • Hillier, L.W.1
  • 9
    • 42249087308 scopus 로고    scopus 로고
    • The complete genome of an individual by massively parallel DNA sequencing
    • Wheeler, D.A. et al. The complete genome of an individual by massively parallel DNA sequencing. Nature 452, 872-876 (2008).
    • (2008) Nature , vol.452 , pp. 872-876
    • Wheeler, D.A.1
  • 11
    • 40749097777 scopus 로고    scopus 로고
    • Genetic basis of fitness differences in natural populations
    • Ellegren, H. & Sheldon, B.C. Genetic basis of fitness differences in natural populations. Nature 452, 169-175 (2008).
    • (2008) Nature , vol.452 , pp. 169-175
    • Ellegren, H.1    Sheldon, B.C.2
  • 12
    • 40849096166 scopus 로고    scopus 로고
    • The road to genome-wide association studies
    • Kruglyak, L. The road to genome-wide association studies. Nat. Rev. Genet. 9, 314-318 (2008).
    • (2008) Nat. Rev. Genet , vol.9 , pp. 314-318
    • Kruglyak, L.1
  • 13
    • 0035865322 scopus 로고    scopus 로고
    • A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms
    • Sachidanandam, R. et al. A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms. Nature 409, 928-933 (2001).
    • (2001) Nature , vol.409 , pp. 928-933
    • Sachidanandam, R.1
  • 14
    • 79959524146 scopus 로고    scopus 로고
    • A haplotype map of the human genome
    • International HapMap Consortium
    • International HapMap Consortium. A haplotype map of the human genome. Nature 437, 1299-1320 (2005).
    • (2005) Nature , vol.437 , pp. 1299-1320
  • 15
    • 35348983887 scopus 로고    scopus 로고
    • A second generation human haplotype map of over 3.1 million SNPs
    • International HapMap Consortium
    • International HapMap Consortium. A second generation human haplotype map of over 3.1 million SNPs. Nature 449, 851-861 (2007).
    • (2007) Nature , vol.449 , pp. 851-861
  • 16
    • 84969213492 scopus 로고    scopus 로고
    • Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
    • Wellcome Trust Case Control Consortium
    • Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 447, 661-678 (2007).
    • (2007) Nature , vol.447 , pp. 661-678
  • 17
    • 40549109924 scopus 로고    scopus 로고
    • Susceptibility to coronary artery disease and diabetes is encoded by distinct, tightly linked SNPs in the ANRIL locus on chromosome 9p
    • Broadbent, H.M. et al. Susceptibility to coronary artery disease and diabetes is encoded by distinct, tightly linked SNPs in the ANRIL locus on chromosome 9p. Hum. Mol. Genet. 17, 806-814 (2008).
    • (2008) Hum. Mol. Genet , vol.17 , pp. 806-814
    • Broadbent, H.M.1
  • 18
    • 41049109562 scopus 로고    scopus 로고
    • Singleton SNPs in the human genome and implications for genome-wide association studies
    • Ke, X., Taylor, M.S. & Cardon, L.R. Singleton SNPs in the human genome and implications for genome-wide association studies. Eur. J. Hum. Genet. 16, 506-515 (2008).
    • (2008) Eur. J. Hum. Genet , vol.16 , pp. 506-515
    • Ke, X.1    Taylor, M.S.2    Cardon, L.R.3
  • 19
    • 3843056691 scopus 로고    scopus 로고
    • Multiple rare alleles contribute to low plasma levels of HDL cholesterol
    • Cohen, J.C. et al. Multiple rare alleles contribute to low plasma levels of HDL cholesterol. Science 305, 869-872 (2004).
    • (2004) Science , vol.305 , pp. 869-872
    • Cohen, J.C.1
  • 20
    • 33847759937 scopus 로고    scopus 로고
    • Schizophrenia: A common disease caused by multiple rare alleles
    • McClellan, J.M., Susser, E. & King, M.-C. Schizophrenia: a common disease caused by multiple rare alleles. Br. J. Psychol. 190, 194-199 (2007).
    • (2007) Br. J. Psychol , vol.190 , pp. 194-199
    • McClellan, J.M.1    Susser, E.2    King, M.-C.3
  • 21
    • 25844490588 scopus 로고    scopus 로고
    • The new cytogenetics: Blurring the boundaries with molecular biology
    • Speicher, M.R. & Carter, N.P. The new cytogenetics: blurring the boundaries with molecular biology. Nat. Rev. Genet. 6, 782-792 (2005).
    • (2005) Nat. Rev. Genet , vol.6 , pp. 782-792
    • Speicher, M.R.1    Carter, N.P.2
  • 22
    • 4444291843 scopus 로고    scopus 로고
    • Detection of large-scale variation in the human genome
    • Iafrate, A.J. et al. Detection of large-scale variation in the human genome. Nat. Genet. 36, 949-951 (2004).
    • (2004) Nat. Genet , vol.36 , pp. 949-951
    • Iafrate, A.J.1
  • 23
    • 33746741125 scopus 로고    scopus 로고
    • Copy number variation: New insights in genome diversity
    • Freeman, J.L. et al. Copy number variation: new insights in genome diversity. Genome Res. 16, 949-961 (2006).
    • (2006) Genome Res , vol.16 , pp. 949-961
    • Freeman, J.L.1
  • 24
    • 33751345434 scopus 로고    scopus 로고
    • Genome-wide detection of human copy number variations using high-density DNA oligonucleotide arrays
    • Komura, D. et al. Genome-wide detection of human copy number variations using high-density DNA oligonucleotide arrays. Genome Res. 16, 1575-1584 (2006).
    • (2006) Genome Res , vol.16 , pp. 1575-1584
    • Komura, D.1
  • 25
    • 33751329250 scopus 로고    scopus 로고
    • Global variation in copy number in the human genome
    • Redon, R. et al. Global variation in copy number in the human genome. Nature 444, 444-454 (2006).
    • (2006) Nature , vol.444 , pp. 444-454
    • Redon, R.1
  • 26
    • 35648976118 scopus 로고    scopus 로고
    • The diploid genome sequence of an individual human
    • Levy, S. et al. The diploid genome sequence of an individual human. PLoS Biol. 5, e254 (2007).
    • (2007) PLoS Biol , vol.5
    • Levy, S.1
  • 27
    • 33746363353 scopus 로고    scopus 로고
    • Structural variants: Changing the landscape of chromosomes and design of disease studies
    • Feuk, L., Marshall, C.R., Wintle, R.F., & Scherer, S.W. Structural variants: changing the landscape of chromosomes and design of disease studies. Hum. Mol. Genet. 15 Spec No 1, R57-R66 (2006).
    • (2006) Hum. Mol. Genet , vol.15 , Issue.SPEC 1
    • Feuk, L.1    Marshall, C.R.2    Wintle, R.F.3    Scherer, S.W.4
  • 28
    • 34347353237 scopus 로고    scopus 로고
    • Copy-number variation and association studies of human disease
    • McCarroll, S.A. & Althshuler, D.M. Copy-number variation and association studies of human disease. Nat. Genet. 39, S37-S42 (2008).
    • (2008) Nat. Genet , vol.39
    • McCarroll, S.A.1    Althshuler, D.M.2
  • 29
    • 33749993417 scopus 로고    scopus 로고
    • The consensus coding sequences of human breast and colorectal cancers
    • Sjoblom, T. et al. The consensus coding sequences of human breast and colorectal cancers. Science 314, 268-274 (2006).
    • (2006) Science , vol.314 , pp. 268-274
    • Sjoblom, T.1
  • 30
    • 36248962105 scopus 로고    scopus 로고
    • The genomic landscapes of human breast and colorectal cancers
    • Wood, L.D. et al. The genomic landscapes of human breast and colorectal cancers. Science 318, 1108-1113 (2007).
    • (2007) Science , vol.318 , pp. 1108-1113
    • Wood, L.D.1
  • 31
    • 44649115241 scopus 로고    scopus 로고
    • Functional Classification Analysis of Somatically Mutated Genes in Human Breast and Colorectal Cancers
    • Chittenden, T. et al. Functional Classification Analysis of Somatically Mutated Genes in Human Breast and Colorectal Cancers. Genomics 91, 508-511 (2008).
    • (2008) Genomics , vol.91 , pp. 508-511
    • Chittenden, T.1
  • 32
    • 34547642493 scopus 로고    scopus 로고
    • Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer
    • Tomlins, S.A. et al. Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer. Nature 448, 595-599 (2007).
    • (2007) Nature , vol.448 , pp. 595-599
    • Tomlins, S.A.1
  • 33
    • 38749145172 scopus 로고    scopus 로고
    • Quantitative monitoring by polymerase colony assay of known mutations resistant to ABL kinase inhibitors
    • Nardi, V. et al. Quantitative monitoring by polymerase colony assay of known mutations resistant to ABL kinase inhibitors. Oncogene 27, 775-782 (2008).
    • (2008) Oncogene , vol.27 , pp. 775-782
    • Nardi, V.1
  • 34
    • 34547829263 scopus 로고    scopus 로고
    • DNA bar coding and pyrosequencing to identify rare HIV drug resistance mutations
    • Hoffmann, C. et al. DNA bar coding and pyrosequencing to identify rare HIV drug resistance mutations. Nucleic Acids Res. 35, e91 (2007).
    • (2007) Nucleic Acids Res , vol.35
    • Hoffmann, C.1
  • 35
    • 34547643929 scopus 로고    scopus 로고
    • Characterization of mutation spectra with ultra-deep pyrosequencing: Application to HIV-1 drug resistance
    • Wang, C., Mitsuya, Y., Gharizadeh, B., Ronaghi, M. & Shafer, R.W. Characterization of mutation spectra with ultra-deep pyrosequencing: application to HIV-1 drug resistance. Genome Res. 17, 1195-1201 (2007).
    • (2007) Genome Res , vol.17 , pp. 1195-1201
    • Wang, C.1    Mitsuya, Y.2    Gharizadeh, B.3    Ronaghi, M.4    Shafer, R.W.5
  • 36
    • 47249120117 scopus 로고    scopus 로고
    • XDR-TB genome sequencing: A glimpse of the microbiology of the future
    • Loman, N.J. & Pallen, M.J. XDR-TB genome sequencing: a glimpse of the microbiology of the future. Future Microbiol. 3, 111-113 (2008).
    • (2008) Future Microbiol , vol.3 , pp. 111-113
    • Loman, N.J.1    Pallen, M.J.2
  • 37
    • 48349124258 scopus 로고    scopus 로고
    • High-throughput sequencing provides insights into genome variation and evolution in Salmonella Typhi
    • Holt, K.E. et al. High-throughput sequencing provides insights into genome variation and evolution in Salmonella Typhi. Nat. Genet. 40, 987-993 (2008).
    • (2008) Nat. Genet , vol.40 , pp. 987-993
    • Holt, K.E.1
  • 38
    • 39749113080 scopus 로고    scopus 로고
    • Clonal integration of a polyomavirus in human Merkel cell carcinoma
    • Feng, H., Shuda, M., Chang, Y. & Moore, P.S. Clonal integration of a polyomavirus in human Merkel cell carcinoma. Science 319, 1096-1100 (2007).
    • (2007) Science , vol.319 , pp. 1096-1100
    • Feng, H.1    Shuda, M.2    Chang, Y.3    Moore, P.S.4
  • 39
    • 40449115382 scopus 로고    scopus 로고
    • A new arenavirus in a cluster of fatal transplant-associated diseases
    • Palacios, G. et al. A new arenavirus in a cluster of fatal transplant-associated diseases. N. Engl. J. Med. 358, 991-998 (2008).
    • (2008) N. Engl. J. Med , vol.358 , pp. 991-998
    • Palacios, G.1
  • 40
    • 35348853758 scopus 로고    scopus 로고
    • A metagenomic survey of microbes in honey bee colony collapse disorder
    • Cox-Foster, D.L. et al. A metagenomic survey of microbes in honey bee colony collapse disorder. Science 318, 283-287 (2007).
    • (2007) Science , vol.318 , pp. 283-287
    • Cox-Foster, D.L.1
  • 41
    • 33750431080 scopus 로고    scopus 로고
    • Symbiosis insights through metagenomic analysis of a microbial consortium
    • Woyke, T. et al. Symbiosis insights through metagenomic analysis of a microbial consortium. Nature 443, 950-955 (2006).
    • (2006) Nature , vol.443 , pp. 950-955
    • Woyke, T.1
  • 42
    • 34547540925 scopus 로고    scopus 로고
    • Dissecting biological "dark matter" with single-cell genetic analysis of rare and uncultivated TM7 microbes from the human mouth
    • Marcy, Y. et al. Dissecting biological "dark matter" with single-cell genetic analysis of rare and uncultivated TM7 microbes from the human mouth. Proc. Natl. Acad. Sci. USA 104, 11889-11894 (2007).
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 11889-11894
    • Marcy, Y.1
  • 43
    • 44349119350 scopus 로고    scopus 로고
    • Diverse syntrophic partnerships from deep-sea methane vents revealed by direct cell capture and metagenomics
    • Pernthaler, A. et al. Diverse syntrophic partnerships from deep-sea methane vents revealed by direct cell capture and metagenomics. Proc. Natl. Acad. Sci. USA 105, 7052-7057 (2008).
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 7052-7057
    • Pernthaler, A.1
  • 44
    • 41649109613 scopus 로고    scopus 로고
    • Functional metagenomic profiling of nine biomes
    • Dinsdale, E.A. et al. Functional metagenomic profiling of nine biomes. Nature 452, 629-632 (2008).
    • (2008) Nature , vol.452 , pp. 629-632
    • Dinsdale, E.A.1
  • 45
    • 45449111362 scopus 로고    scopus 로고
    • Systems toxicology' approach identifies coordinated metabolic responses to copper in a terrestrial non-model invertebrate, the earthworm Lumbricus rubellus
    • Bundy, J.G. et al. 'Systems toxicology' approach identifies coordinated metabolic responses to copper in a terrestrial non-model invertebrate, the earthworm Lumbricus rubellus. BMC Biol. 6, 25 (2008).
    • (2008) BMC Biol , vol.6 , pp. 25
    • Bundy, J.G.1
  • 46
    • 53649098239 scopus 로고    scopus 로고
    • Genomics technology for assessing soil pollution
    • van Straalen, N.M. & Roelofs, D. Genomics technology for assessing soil pollution. J. Biol. 7, 19 (2008).
    • (2008) J. Biol , vol.7 , pp. 19
    • van Straalen, N.M.1    Roelofs, D.2
  • 47
    • 35348968286 scopus 로고    scopus 로고
    • The human microbiome project
    • Turnbaugh, P.J. et al. The human microbiome project. Nature 449, 804-810 (2007).
    • (2007) Nature , vol.449 , pp. 804-810
    • Turnbaugh, P.J.1
  • 48
    • 38349135680 scopus 로고    scopus 로고
    • High-resolution mapping of DNA hypermethylation and hypomethylation in lung cancer
    • Rauch, T.A. et al. High-resolution mapping of DNA hypermethylation and hypomethylation in lung cancer. Proc. Natl. Acad. Sci. USA 105, 252-257 (2007).
    • (2007) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 252-257
    • Rauch, T.A.1
  • 49
    • 37649022627 scopus 로고    scopus 로고
    • Integrated epigenomic analyses of neuronal MeCP2 reveal a role for long-range interaction with active genes
    • Yasui, D.H. et al. Integrated epigenomic analyses of neuronal MeCP2 reveal a role for long-range interaction with active genes. Proc. Natl. Acad. Sci. USA 104, 19416-19421 (2007).
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 19416-19421
    • Yasui, D.H.1
  • 50
    • 42649089780 scopus 로고    scopus 로고
    • The methylome: Approaches for global DNA methylation profiling
    • Beck, S. & Rakyan, V.K. The methylome: approaches for global DNA methylation profiling. Trends Genet. 24, 231-237 (2008).
    • (2008) Trends Genet , vol.24 , pp. 231-237
    • Beck, S.1    Rakyan, V.K.2
  • 51
    • 0036144883 scopus 로고    scopus 로고
    • Methylation-specific oligonucleotide microarray: A new potential for high-throughput methylation analysis
    • Gitan, R.S., Shi, H., Chen, C.M., Yan, P.S. & Huang, T.H. Methylation-specific oligonucleotide microarray: a new potential for high-throughput methylation analysis. Genome Res. 12, 158-164 (2002).
    • (2002) Genome Res , vol.12 , pp. 158-164
    • Gitan, R.S.1    Shi, H.2    Chen, C.M.3    Yan, P.S.4    Huang, T.H.5
  • 52
    • 23044499067 scopus 로고    scopus 로고
    • Distinct epigenetic changes in the stromal cells of breast cancers
    • Hu, M. et al. Distinct epigenetic changes in the stromal cells of breast cancers. Nat. Genet. 37, 899-905 (2005).
    • (2005) Nat. Genet , vol.37 , pp. 899-905
    • Hu, M.1
  • 53
    • 33745056414 scopus 로고    scopus 로고
    • Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer
    • Agrelo, R. et al. Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer. Proc. Natl. Acad. Sci. USA 103, 8822-8827 (2006).
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 8822-8827
    • Agrelo, R.1
  • 54
    • 33646367930 scopus 로고    scopus 로고
    • Quantitative assessment of DNA methylation: Potential applications for disease diagnosis, classification, and prognosis in clinical settings
    • Brena, R.M., Huang, T.H. & Plass, C. Quantitative assessment of DNA methylation: potential applications for disease diagnosis, classification, and prognosis in clinical settings. J. Mol. Med. 84, 365-377 (2006).
    • (2006) J. Mol. Med , vol.84 , pp. 365-377
    • Brena, R.M.1    Huang, T.H.2    Plass, C.3
  • 55
    • 23044514669 scopus 로고    scopus 로고
    • Epigenetic differences arise during the lifetime of monozygotic twins
    • Fraga, M.F. et al. Epigenetic differences arise during the lifetime of monozygotic twins. Proc. Natl. Acad. Sci. USA 102, 10604-10609 (2005).
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 10604-10609
    • Fraga, M.F.1
  • 56
    • 29244457579 scopus 로고    scopus 로고
    • A blueprint for a Human Epigenome Project: The AACR Human Epigenome Workshop
    • Jones, P.A. & Martienssen, R. A blueprint for a Human Epigenome Project: the AACR Human Epigenome Workshop. Cancer Res. 65, 11241-11246 (2005).
    • (2005) Cancer Res , vol.65 , pp. 11241-11246
    • Jones, P.A.1    Martienssen, R.2
  • 57
    • 31544478804 scopus 로고    scopus 로고
    • Momentum building for human epigenome project
    • Garber, K. Momentum building for human epigenome project. J. Natl. Cancer Inst. 98, 84-86 (2006).
    • (2006) J. Natl. Cancer Inst , vol.98 , pp. 84-86
    • Garber, K.1
  • 58
    • 33745602221 scopus 로고    scopus 로고
    • The necessity of a human epigenome project
    • Esteller, M. The necessity of a human epigenome project. Carcinogenesis 27, 1121-1125 (2006).
    • (2006) Carcinogenesis , vol.27 , pp. 1121-1125
    • Esteller, M.1
  • 59
    • 33751505540 scopus 로고    scopus 로고
    • DNA methylation profiling of human chromosomes 6, 20 and 22
    • Eckhardt, F. et al. DNA methylation profiling of human chromosomes 6, 20 and 22. Nat. Genet. 38, 1378-1385 (2006).
    • (2006) Nat. Genet , vol.38 , pp. 1378-1385
    • Eckhardt, F.1
  • 60
    • 33748629119 scopus 로고    scopus 로고
    • Genome-wide high-resolution mapping and functional analysis of DNA methylation in Arabidopsis
    • Zhang, X. et al. Genome-wide high-resolution mapping and functional analysis of DNA methylation in Arabidopsis. Cell 126, 1189-1201 (2006).
    • (2006) Cell , vol.126 , pp. 1189-1201
    • Zhang, X.1
  • 61
    • 43749099875 scopus 로고    scopus 로고
    • Nucleosome organization in the Drosophila genome
    • Mavrich, T.N. et al. Nucleosome organization in the Drosophila genome. Nature 453, 358-362 (2008).
    • (2008) Nature , vol.453 , pp. 358-362
    • Mavrich, T.N.1
  • 62
    • 46449103738 scopus 로고    scopus 로고
    • A high-resolution, nucleosome position map of C. elegans reveals a lack of universal sequence-dictated positioning
    • Valouev, A. et al. A high-resolution, nucleosome position map of C. elegans reveals a lack of universal sequence-dictated positioning. Genome Res. 18, 1051-1063 (2008).
    • (2008) Genome Res , vol.18 , pp. 1051-1063
    • Valouev, A.1
  • 63
    • 33646510364 scopus 로고    scopus 로고
    • Genome-wide analysis of protein-DNA interactions
    • Kim, T.H. & Ren, B. Genome-wide analysis of protein-DNA interactions. Annu. Rev. Genomics Hum. Genet. 7, 81-102 (2006).
    • (2006) Annu. Rev. Genomics Hum. Genet , vol.7 , pp. 81-102
    • Kim, T.H.1    Ren, B.2
  • 64
    • 48749124117 scopus 로고    scopus 로고
    • ChIPping away at gene regulation
    • 337-343
    • Massie, C.E. & Mills, I.G. ChIPping away at gene regulation. EMBO Rep. 9, 337-343 (2008).
    • (2008) EMBO Rep , vol.9
    • Massie, C.E.1    Mills, I.G.2
  • 65
    • 44349096486 scopus 로고    scopus 로고
    • Chromatin state maps: New technologies, new insights
    • Mendenhall, E.M. & Bernstein, B.E. Chromatin state maps: new technologies, new insights. Curr. Opin. Genet. Dev. 18, 109-115 (2008).
    • (2008) Curr. Opin. Genet. Dev , vol.18 , pp. 109-115
    • Mendenhall, E.M.1    Bernstein, B.E.2
  • 66
    • 34547633677 scopus 로고    scopus 로고
    • Genome-wide profiles of STAT1 DNA association using chromatin immunoprecipitation and massively parallel sequencing
    • Robertson, G. et al. Genome-wide profiles of STAT1 DNA association using chromatin immunoprecipitation and massively parallel sequencing. Nat. Methods 4, 651-657 (2007).
    • (2007) Nat. Methods , vol.4 , pp. 651-657
    • Robertson, G.1
  • 67
    • 34250332235 scopus 로고    scopus 로고
    • Mapping of transcription factor binding regions in mammalian cells by ChIP: Comparison of array- and sequencing-based technologies
    • Euskirchen, G.M. et al. Mapping of transcription factor binding regions in mammalian cells by ChIP: comparison of array- and sequencing-based technologies. Genome Res. 17, 898-909 (2007).
    • (2007) Genome Res , vol.17 , pp. 898-909
    • Euskirchen, G.M.1
  • 68
    • 34250159524 scopus 로고    scopus 로고
    • Genome-wide mapping of in vivo protein-DNA interactions
    • Johnson, D.S., Mortazavi, A., Myers, R.M. & Wold, B. Genome-wide mapping of in vivo protein-DNA interactions. Science 316, 1497-1502 (2007).
    • (2007) Science , vol.316 , pp. 1497-1502
    • Johnson, D.S.1    Mortazavi, A.2    Myers, R.M.3    Wold, B.4
  • 69
    • 34249026300 scopus 로고    scopus 로고
    • High-resolution profiling of histone methylations in the human genome
    • Barski, A. et al. High-resolution profiling of histone methylations in the human genome. Cell 129, 823-837 (2007).
    • (2007) Cell , vol.129 , pp. 823-837
    • Barski, A.1
  • 70
    • 33846006550 scopus 로고    scopus 로고
    • Genome-wide prediction of conserved and nonconserved enhancers by histone acetylation patterns
    • Roh, T.Y., Wei, G., Farrell, C.M. & Zhao, K. Genome-wide prediction of conserved and nonconserved enhancers by histone acetylation patterns. Genome Res. 17, 74-81 (2007).
    • (2007) Genome Res , vol.17 , pp. 74-81
    • Roh, T.Y.1    Wei, G.2    Farrell, C.M.3    Zhao, K.4
  • 71
    • 43149122898 scopus 로고    scopus 로고
    • Monoubiquitinated H2B is associated with the transcribed region of highly expressed genes in human cells
    • Minsky, N. et al. Monoubiquitinated H2B is associated with the transcribed region of highly expressed genes in human cells. Nat. Cell Biol. 10, 483-488 (2008).
    • (2008) Nat. Cell Biol , vol.10 , pp. 483-488
    • Minsky, N.1
  • 72
    • 34547624303 scopus 로고    scopus 로고
    • Genome-wide maps of chromatin state in pluripotent and lineage-committed cells
    • Mikkelsen, T.S. et al. Genome-wide maps of chromatin state in pluripotent and lineage-committed cells. Nature 448, 553-560 (2007).
    • (2007) Nature , vol.448 , pp. 553-560
    • Mikkelsen, T.S.1
  • 73
    • 49649125042 scopus 로고    scopus 로고
    • Genome-scale DNA methylation maps of pluirpotent and differentiated cells
    • Meissner, A. et al. Genome-scale DNA methylation maps of pluirpotent and differentiated cells. Nature 454, 766-770 (2008).
    • (2008) Nature , vol.454 , pp. 766-770
    • Meissner, A.1
  • 74
    • 25144525014 scopus 로고    scopus 로고
    • Core transcriptional regulatory circuitry in human embryonic stem cells
    • Boyer, L.A. et al. Core transcriptional regulatory circuitry in human embryonic stem cells. Cell 122, 947-956 (2005).
    • (2005) Cell , vol.122 , pp. 947-956
    • Boyer, L.A.1
  • 75
    • 33646865180 scopus 로고    scopus 로고
    • Control of developmental regulators by Polycomb in human embryonic stem cells
    • Lee, T.I. et al. Control of developmental regulators by Polycomb in human embryonic stem cells. Cell 125, 301-313 (2006).
    • (2006) Cell , vol.125 , pp. 301-313
    • Lee, T.I.1
  • 76
    • 33646547951 scopus 로고    scopus 로고
    • Systems biology approaches identify ATF3 as a negative regulator of Toll-like receptor 4
    • Gilchrist, M. et al. Systems biology approaches identify ATF3 as a negative regulator of Toll-like receptor 4. Nature 441, 173-178 (2006).
    • (2006) Nature , vol.441 , pp. 173-178
    • Gilchrist, M.1
  • 77
    • 23644453736 scopus 로고    scopus 로고
    • Three microarray platforms: An analysis of their concordance in profiling gene expression
    • Petersen, D. et al. Three microarray platforms: an analysis of their concordance in profiling gene expression. BMC Genomics 6, 63 (2005).
    • (2005) BMC Genomics , vol.6 , pp. 63
    • Petersen, D.1
  • 78
    • 34250305146 scopus 로고    scopus 로고
    • Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project
    • Encode Project Consortium
    • Encode Project Consortium. Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature 447, 799-816 (2007).
    • (2007) Nature , vol.447 , pp. 799-816
  • 79
    • 0037012881 scopus 로고    scopus 로고
    • Large-scale transcriptional activity in chromosomes 21 and 22
    • Kapranov, P. et al. Large-scale transcriptional activity in chromosomes 21 and 22. Science 296, 916-919 (2002).
    • (2002) Science , vol.296 , pp. 916-919
    • Kapranov, P.1
  • 80
    • 21044431735 scopus 로고    scopus 로고
    • Transcriptional maps of 10 human chromosomes at 5-nucleotide resolution
    • Cheng, J. et al. Transcriptional maps of 10 human chromosomes at 5-nucleotide resolution. Science 308, 1149-1154 (2005).
    • (2005) Science , vol.308 , pp. 1149-1154
    • Cheng, J.1
  • 81
    • 22244442468 scopus 로고    scopus 로고
    • Examples of the complex architecture of the human transcriptome revealed by RACE and high-density tiling arrays
    • Kapranov, P. et al. Examples of the complex architecture of the human transcriptome revealed by RACE and high-density tiling arrays. Genome Res. 15, 987-997 (2005).
    • (2005) Genome Res , vol.15 , pp. 987-997
    • Kapranov, P.1
  • 82
    • 0141493493 scopus 로고    scopus 로고
    • Control of leaf morphogenesis by microRNAs
    • Palatnik, J.F. et al. Control of leaf morphogenesis by microRNAs. Nature 425, 257-263 (2003).
    • (2003) Nature , vol.425 , pp. 257-263
    • Palatnik, J.F.1
  • 83
    • 20444460289 scopus 로고    scopus 로고
    • MicroRNA expression profiles classify human cancers
    • Lu, J. et al. MicroRNA expression profiles classify human cancers. Nature 435, 834-838 (2005).
    • (2005) Nature , vol.435 , pp. 834-838
    • Lu, J.1
  • 84
    • 24144494563 scopus 로고    scopus 로고
    • The let-7 MicroRNA family members mir-48, mir-84, and mir-241 function together to regulate developmental timing in Caenorhabditis elegans
    • Abbott, A.L. et al. The let-7 MicroRNA family members mir-48, mir-84, and mir-241 function together to regulate developmental timing in Caenorhabditis elegans. Dev. Cell 9, 403-414 (2005).
    • (2005) Dev. Cell , vol.9 , pp. 403-414
    • Abbott, A.L.1
  • 85
    • 33750370444 scopus 로고    scopus 로고
    • MicroRNA signatures in human cancers
    • Calin, G.A. & Croce, C.M. MicroRNA signatures in human cancers. Nat. Rev. Cancer 6, 857-866 (2006).
    • (2006) Nat. Rev. Cancer , vol.6 , pp. 857-866
    • Calin, G.A.1    Croce, C.M.2
  • 86
    • 33747876113 scopus 로고    scopus 로고
    • MicroRNA-cancer connection: The beginning of a new tale
    • Calin, G.A. & Croce, C.M. MicroRNA-cancer connection: the beginning of a new tale. Cancer Res. 66, 7390-7394 (2006).
    • (2006) Cancer Res , vol.66 , pp. 7390-7394
    • Calin, G.A.1    Croce, C.M.2
  • 87
    • 38849107424 scopus 로고    scopus 로고
    • The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis
    • Huang, Q. et al. The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis. Nat. Cell Biol. 10, 202-210 (2008).
    • (2008) Nat. Cell Biol , vol.10 , pp. 202-210
    • Huang, Q.1
  • 88
    • 41649106136 scopus 로고    scopus 로고
    • Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells
    • Morin, R.D. et al. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. Genome Res. 18, 610-621 (2008).
    • (2008) Genome Res , vol.18 , pp. 610-621
    • Morin, R.D.1
  • 89
    • 38049155825 scopus 로고    scopus 로고
    • Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA
    • Yu, W. et al. Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA. Nature 451, 202-206 (2008).
    • (2008) Nature , vol.451 , pp. 202-206
    • Yu, W.1
  • 90
    • 33846252240 scopus 로고    scopus 로고
    • Genome-wide atlas of gene expression in the adult mouse brain
    • Lein, E.S. et al. Genome-wide atlas of gene expression in the adult mouse brain. Nature 445, 168-176 (2007).
    • (2007) Nature , vol.445 , pp. 168-176
    • Lein, E.S.1
  • 91
    • 34247202571 scopus 로고    scopus 로고
    • Gene expression profiles in anatomically and functionally distinct regions of the normal aged human brain
    • Liang, W.S. et al. Gene expression profiles in anatomically and functionally distinct regions of the normal aged human brain. Physiol. Genomics 28, 311-322 (2006).
    • (2006) Physiol. Genomics , vol.28 , pp. 311-322
    • Liang, W.S.1
  • 92
    • 36549053104 scopus 로고    scopus 로고
    • A survey of genetic human cortical gene expression
    • Myers, A.J. et al. A survey of genetic human cortical gene expression. Nat. Genet. 39, 1494-1499 (2007).
    • (2007) Nat. Genet , vol.39 , pp. 1494-1499
    • Myers, A.J.1
  • 93
    • 26444502673 scopus 로고    scopus 로고
    • A microarray configuration to quantify expression levels and relative abundance of splice variants
    • Fehlbaum, P., Guihal, C., Bracco, L. & Cochet, O. A microarray configuration to quantify expression levels and relative abundance of splice variants. Nucleic Acids Res. 33, e47 (2005).
    • (2005) Nucleic Acids Res , vol.33
    • Fehlbaum, P.1    Guihal, C.2    Bracco, L.3    Cochet, O.4
  • 94
    • 38649090044 scopus 로고    scopus 로고
    • Genome-wide analysis of transcript isoform variation in humans
    • Kwan, T. et al. Genome-wide analysis of transcript isoform variation in humans. Nat. Genet. 40, 225-231 (2008).
    • (2008) Nat. Genet , vol.40 , pp. 225-231
    • Kwan, T.1
  • 95
    • 33745899048 scopus 로고    scopus 로고
    • Alternative splicing: New insights from global analyses
    • Blencowe, B.J. Alternative splicing: new insights from global analyses. Cell 126, 37-47 (2006).
    • (2006) Cell , vol.126 , pp. 37-47
    • Blencowe, B.J.1
  • 97
    • 2442679088 scopus 로고    scopus 로고
    • SAGE is far more sensitive than EST for detecting low-abundance transcripts
    • Sun, M. et al. SAGE is far more sensitive than EST for detecting low-abundance transcripts. BMC Genomics 5, 1-4 (2004).
    • (2004) BMC Genomics , vol.5 , pp. 1-4
    • Sun, M.1
  • 98
    • 39549084088 scopus 로고    scopus 로고
    • LongSAGE profiling of nine human embryonic stem cell lines
    • Hirst, M. et al. LongSAGE profiling of nine human embryonic stem cell lines. Genome Biol. 8, R113 (2007).
    • (2007) Genome Biol , vol.8
    • Hirst, M.1
  • 100
    • 46249103973 scopus 로고    scopus 로고
    • Stem cell transcriptome profiling via massive-scale mRNA sequencing
    • Cloonan, N. et al. Stem cell transcriptome profiling via massive-scale mRNA sequencing. Nat. Methods 5, 613-619 (2008).
    • (2008) Nat. Methods , vol.5 , pp. 613-619
    • Cloonan, N.1
  • 101
    • 48249148300 scopus 로고    scopus 로고
    • Transcriptome analysis for Caenorhabditis elegans based on novel expressed sequence tags
    • Shin, H. et al. Transcriptome analysis for Caenorhabditis elegans based on novel expressed sequence tags. BMC Biol. 6, 30 (2008).
    • (2008) BMC Biol , vol.6 , pp. 30
    • Shin, H.1
  • 102
    • 47949084846 scopus 로고    scopus 로고
    • Profiling the HeLa S3 transcriptome using randomly primed cDNA and massively parallel short-read sequencing
    • Morin, R. et al. Profiling the HeLa S3 transcriptome using randomly primed cDNA and massively parallel short-read sequencing. Biotechniques 45, 81-94 (2008).
    • (2008) Biotechniques , vol.45 , pp. 81-94
    • Morin, R.1
  • 103
    • 45549088326 scopus 로고    scopus 로고
    • The transcriptional landscape of the yeast genome defined by RNA sequencing
    • Nagalakshmi, U. et al. The transcriptional landscape of the yeast genome defined by RNA sequencing. Science 320, 1344-1349 (2008).
    • (2008) Science , vol.320 , pp. 1344-1349
    • Nagalakshmi, U.1
  • 104
    • 46249096804 scopus 로고    scopus 로고
    • Dynamic repertoire of a eukaryotic transcriptome surveyed at single-nucleotide resolution
    • Wilhelm, B.T. et al. Dynamic repertoire of a eukaryotic transcriptome surveyed at single-nucleotide resolution. Nature 453, 1239-1243 (2008).
    • (2008) Nature , vol.453 , pp. 1239-1243
    • Wilhelm, B.T.1
  • 105
    • 33750204290 scopus 로고    scopus 로고
    • Genetics of global gene expression
    • Rockman, M.V. & Kruglyak, L. Genetics of global gene expression. Nat. Rev. Genet. 7, 862-872 (2006).
    • (2006) Nat. Rev. Genet , vol.7 , pp. 862-872
    • Rockman, M.V.1    Kruglyak, L.2
  • 106
    • 0037456823 scopus 로고    scopus 로고
    • Genetics of gene expression surveyed in maize, mouse and man
    • Schadt, E.E. et al. Genetics of gene expression surveyed in maize, mouse and man. Nature 422, 297-302 (2003).
    • (2003) Nature , vol.422 , pp. 297-302
    • Schadt, E.E.1
  • 107
    • 40749105508 scopus 로고    scopus 로고
    • Variations in DNA elucidate molecular networks that cause disease
    • Chen, Y. et al. Variations in DNA elucidate molecular networks that cause disease. Nature 452, 429-435 (2008).
    • (2008) Nature , vol.452 , pp. 429-435
    • Chen, Y.1
  • 108
    • 33744475085 scopus 로고    scopus 로고
    • A regulatory SNP causes a human genetic disease by creating a new transcriptional promoter
    • De Gobbi, M. et al. A regulatory SNP causes a human genetic disease by creating a new transcriptional promoter. Science 312, 1215-1217 (2006).
    • (2006) Science , vol.312 , pp. 1215-1217
    • De Gobbi, M.1
  • 109
    • 42749087226 scopus 로고    scopus 로고
    • Highly integrated single-base resolution maps of the epigenome in Arabidopsis
    • Lister, R. et al. Highly integrated single-base resolution maps of the epigenome in Arabidopsis. Cell 133, 523-536 (2008).
    • (2008) Cell , vol.133 , pp. 523-536
    • Lister, R.1
  • 110
    • 3042855581 scopus 로고    scopus 로고
    • Optimization of probe length and the number of probes per gene for optimal microarray analysis of gene expression
    • Chou, C.C., Chen, C.H., Lee, T.T. & Peck, K. Optimization of probe length and the number of probes per gene for optimal microarray analysis of gene expression. Nucleic Acids Res. 32, e99 (2004).
    • (2004) Nucleic Acids Res , vol.32
    • Chou, C.C.1    Chen, C.H.2    Lee, T.T.3    Peck, K.4
  • 111
    • 46249130709 scopus 로고    scopus 로고
    • The beginning of the end for microarrays?
    • Shendure, J. The beginning of the end for microarrays? Nat. Genet. 5, 585-586 (2008).
    • (2008) Nat. Genet , vol.5 , pp. 585-586
    • Shendure, J.1
  • 112
    • 39649084637 scopus 로고    scopus 로고
    • Bioinformatics challenges of new sequencing technology
    • Pop, M. & Salzburg, S.L. Bioinformatics challenges of new sequencing technology. Trends Genet. 24, 142-149 (2008).
    • (2008) Trends Genet , vol.24 , pp. 142-149
    • Pop, M.1    Salzburg, S.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.