Single-molecule DNA sequencing of a viral genome

Science

Volumn 320, Issue 5872, 2008, Pages 106-109

  Harris, Timothy D ^a   Buzby, Phillip R ^a   Babcock, Hazen ^a   Beer, Eric ^a   Bowers, Jayson ^a   Braslavsky, Ido ^b   Causey, Marie ^a   Colonell, Jennifer ^a   DiMeo, James ^a   Efcavitch, J William ^a   Giladi, Eldar ^a   Gill, Jaime ^a   Healy, John ^a   Jarosz, Mirna ^a   Lapen, Dan ^a   Moulton, Keith ^a   Quake, Stephen R ^c   Steinmann, Kathleen ^a   Thayer, Edward ^a   Tyurina, Anastasia ^a   Ward, Rebecca ^a   Weiss, Howard ^a   Xie, Zheng ^a   more..

^a Helicos BioSciences   (United States)

^b OHIO UNIVERSITY   (United States)

^c Stanford University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; DNA POLYMERASE; NUCLEOTIDE;

COMPARATIVE STUDY; COST-BENEFIT ANALYSIS; DNA; ENZYME ACTIVITY; FLUORESCENCE; GENOME; HOMINID; MICROSCOPY; MUTATION; SOFTWARE; VIRUS;

ARTICLE; COMPUTER PROGRAM; DNA SEQUENCE; FLUORESCENCE; MUTATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; VIRUS; VIRUS GENOME;

ALGORITHMS; BACTERIOPHAGE M13; COMPUTATIONAL BIOLOGY; DNA PRIMERS; DNA, VIRAL; GENOME, VIRAL; MUTATION; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, DNA; SOFTWARE; TEMPLATES, GENETIC;

EID: 41749104588     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1150427     Document Type: Article

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16. We thank M. Mrksich, G. Church, D. Crothers, S. Chu, F. Romesberg, N. Afeyan, P. Milos, E. Lander, and S. Lapidus for many valuable discussions. This work was supported in part by NIH grant R01 HG004144-01. S.R.Q. and I.B. are paid consultants for and own equity in HelicosBioSciences Corp. S.R.Q. and I.B. are also inventors of a licensed patent on single-molecule sequencing that may yield royalty payments.