-
1
-
-
0035821279
-
Pathophysiology of chronic heart failure
-
Francis GS. Pathophysiology of chronic heart failure. Am J Med 2001; 110: 37S-46S.
-
(2001)
Am J Med
, vol.110
-
-
Francis, G.S.1
-
2
-
-
0034649248
-
Congestive heart failure: Fifty years of progress
-
IV-14, IV-23
-
Braunwald E, Bristow MR. Congestive heart failure: Fifty years of progress. Circulation 2000; 102(Suppl): IV-14 - IV-23.
-
(2000)
Circulation
, vol.102
, Issue.SUPPL.
-
-
Braunwald, E.1
Bristow, M.R.2
-
3
-
-
0036702666
-
Calcium cycling in congestive heart failure
-
Hasenfuss G, Pieske B. Calcium cycling in congestive heart failure. J Mol Cell Cardiol 2002; 34: 951-969.
-
(2002)
J Mol Cell Cardiol
, vol.34
, pp. 951-969
-
-
Hasenfuss, G.1
Pieske, B.2
-
6
-
-
0035916903
-
Decreased sarcoplasmic reticulum calcium content is responsible for defective excitation-contraction coupling in canine heart failure
-
Hobai IA, O'Rourke B. Decreased sarcoplasmic reticulum calcium content is responsible for defective excitation-contraction coupling in canine heart failure. Circulation 2001; 103: 1577-1584.
-
(2001)
Circulation
, vol.103
, pp. 1577-1584
-
-
Hobai, I.A.1
O'Rourke, B.2
-
7
-
-
0035827719
-
Arrhythmogenesis and contractile dysfunction in heart failure: Roles of sodium-calcium exchange, inward rectifier potassium current, and residual beta-adrenergic responsiveness
-
Pogwizd SM, Schlotthauer K, Li L, Yuan W, Bers DM. Arrhythmogenesis and contractile dysfunction in heart failure: Roles of sodium-calcium exchange, inward rectifier potassium current, and residual beta-adrenergic responsiveness. Circ Res 2001; 88: 1159-1167.
-
(2001)
Circ Res
, vol.88
, pp. 1159-1167
-
-
Pogwizd, S.M.1
Schlotthauer, K.2
Li, L.3
Yuan, W.4
Bers, D.M.5
-
8
-
-
0344284562
-
Cellular basis of abnormal calcium transients of failing human ventricular myocytes
-
Piacentino V 3rd, Weber CR, Chen X, Weisser-Thomas J, Margulies KB, Bers DM, et al. Cellular basis of abnormal calcium transients of failing human ventricular myocytes. Circ Res 2003; 92: 651-658.
-
(2003)
Circ Res
, vol.92
, pp. 651-658
-
-
Piacentino 3rd, V.1
Weber, C.R.2
Chen, X.3
Weisser-Thomas, J.4
Margulies, K.B.5
Bers, D.M.6
-
11
-
-
3242692393
-
Macromolecular complexes regulating cardiac ryanodine receptor function (Review)
-
Bers DM. Macromolecular complexes regulating cardiac ryanodine receptor function (Review). J Mol Cell Cardiol 2004; 37: 417-429.
-
(2004)
J Mol Cell Cardiol
, vol.37
, pp. 417-429
-
-
Bers, D.M.1
-
12
-
-
17944398302
-
Calcium-induced release of calcium from the cardiac sarcoplasmic reticulum (Review)
-
Fabiato A. Calcium-induced release of calcium from the cardiac sarcoplasmic reticulum (Review). Am J Physiol 1983; 245: C1-C14.
-
(1983)
Am J Physiol
, vol.245
-
-
Fabiato, A.1
-
13
-
-
0037049977
-
Cardiac excitation-contraction coupling
-
Bers DM. Cardiac excitation-contraction coupling. Nature 2002; 415: 198-205.
-
(2002)
Nature
, vol.415
, pp. 198-205
-
-
Bers, D.M.1
-
14
-
-
0001078987
-
Alterations of calcium-regulatory proteins in heart failure
-
Hasenfuss G. Alterations of calcium-regulatory proteins in heart failure. Cardiovasc Res 1998; 37: 279-289.
-
(1998)
Cardiovasc Res
, vol.37
, pp. 279-289
-
-
Hasenfuss, G.1
-
15
-
-
0032497272
-
Increased availability and open probability of single L-type calcium channels from failing compared with nonfailing human ventricle
-
Shröder F, Handrock R, Beuckelmann DJ, Hirt S, Hullin R, Priebe L, et al. Increased availability and open probability of single L-type calcium channels from failing compared with nonfailing human ventricle. Circulation 1998; 98: 969-976.
-
(1998)
Circulation
, vol.98
, pp. 969-976
-
-
Shröder, F.1
Handrock, R.2
Beuckelmann, D.J.3
Hirt, S.4
Hullin, R.5
Priebe, L.6
-
17
-
-
0032723892
-
2+ sparks, and local control of excitation-contraction coupling in normal heart muscle
-
2+ sparks, and local control of excitation-contraction coupling in normal heart muscle. Circ Res 1999; 85: 770-776.
-
(1999)
Circ Res
, vol.85
, pp. 770-776
-
-
Wier, W.G.1
Balke, C.W.2
-
18
-
-
0030023975
-
High frequency-induced upregulation of human cardiac calcium currents
-
Piot C, Lemaire S, Albat B, Seguin J, Nargeot J, Richard S. High frequency-induced upregulation of human cardiac calcium currents. Circulation 1996; 93: 120-128.
-
(1996)
Circulation
, vol.93
, pp. 120-128
-
-
Piot, C.1
Lemaire, S.2
Albat, B.3
Seguin, J.4
Nargeot, J.5
Richard, S.6
-
19
-
-
0343526373
-
Facilitation of L-type calcium currents by diastolic depolarization in cardiac cells: Impairment in heart failure
-
Barrere-Lemaire S, Piot C, Leclercq F, Nargeot J, Richard S. Facilitation of L-type calcium currents by diastolic depolarization in cardiac cells: Impairment in heart failure. Cardiovasc Res 2000; 47: 336-349.
-
(2000)
Cardiovasc Res
, vol.47
, pp. 336-349
-
-
Barrere-Lemaire, S.1
Piot, C.2
Leclercq, F.3
Nargeot, J.4
Richard, S.5
-
21
-
-
1842294625
-
Defective excitation-contraction coupling in experimental cardiac hypertrophy and heart failure
-
Gomez AM, Valdivia HH, Cheng H, Lederer MR, Santana LF, Cannell MB, et al. Defective excitation-contraction coupling in experimental cardiac hypertrophy and heart failure. Science 1997; 276: 800-806.
-
(1997)
Science
, vol.276
, pp. 800-806
-
-
Gomez, A.M.1
Valdivia, H.H.2
Cheng, H.3
Lederer, M.R.4
Santana, L.F.5
Cannell, M.B.6
-
22
-
-
0032054635
-
Calcium content of the sarcoplasmic reticulum in isolated ventricular myocytes from patients with terminal heart failure
-
Lindner M, Erdmann E, Beuckelmann DJ. Calcium content of the sarcoplasmic reticulum in isolated ventricular myocytes from patients with terminal heart failure. J Mol Cell Cardiol 1998; 30: 743-749.
-
(1998)
J Mol Cell Cardiol
, vol.30
, pp. 743-749
-
-
Lindner, M.1
Erdmann, E.2
Beuckelmann, D.J.3
-
26
-
-
0035827726
-
Coupled gating between cardiac calcium release channels (ryanodine receptors)
-
Marx SO, Gaburjakova J, Gaburjakova M, Henrikson C, Ondrias K, Marks AR. Coupled gating between cardiac calcium release channels (ryanodine receptors). Circ Res 2001; 88: 1151-1158.
-
(2001)
Circ Res
, vol.88
, pp. 1151-1158
-
-
Marx, S.O.1
Gaburjakova, J.2
Gaburjakova, M.3
Henrikson, C.4
Ondrias, K.5
Marks, A.R.6
-
28
-
-
3242692393
-
Macromolecular complexes regulating cardiac ryanodine receptor function
-
Bers DM. Macromolecular complexes regulating cardiac ryanodine receptor function. J Mol Cell Cardiol 2004; 37: 417-429.
-
(2004)
J Mol Cell Cardiol
, vol.37
, pp. 417-429
-
-
Bers, D.M.1
-
29
-
-
0034640113
-
PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): Defective regulation in failing hearts
-
Marx SO, Reiken S, Hisamatsu Y, Jayaraman T, Burkhoff D, Rosemblit N, et al. PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): Defective regulation in failing hearts. Cell 2000; 101: 365-376.
-
(2000)
Cell
, vol.101
, pp. 365-376
-
-
Marx, S.O.1
Reiken, S.2
Hisamatsu, Y.3
Jayaraman, T.4
Burkhoff, D.5
Rosemblit, N.6
-
30
-
-
0024318429
-
Primary structure and expression from complementary DNA of skeletal muscle ryanodine receptor
-
Takeshima H, Nishimura S, Matsumoto T, Ishida H, Kangawa K, Minamino N, et al. Primary structure and expression from complementary DNA of skeletal muscle ryanodine receptor. Nature 1989; 339: 439-445.
-
(1989)
Nature
, vol.339
, pp. 439-445
-
-
Takeshima, H.1
Nishimura, S.2
Matsumoto, T.3
Ishida, H.4
Kangawa, K.5
Minamino, N.6
-
32
-
-
0026471048
-
Primary structure and distribution of a novel ryanodine receptor/calcium release channel from rabbit brain
-
Hakamata Y, Nakai J, Takeshima H, Imoto K. Primary structure and distribution of a novel ryanodine receptor/calcium release channel from rabbit brain. FEBS Lett 1992; 312: 229-235.
-
(1992)
FEBS Lett
, vol.312
, pp. 229-235
-
-
Hakamata, Y.1
Nakai, J.2
Takeshima, H.3
Imoto, K.4
-
33
-
-
0028349030
-
Structure and development of E-C coupling units in skeletal muscle
-
Franzini-Armstrong C, Jorgensen AO. Structure and development of E-C coupling units in skeletal muscle. Annu Rev Physiol 1994; 56: 509-534.
-
(1994)
Annu Rev Physiol
, vol.56
, pp. 509-534
-
-
Franzini-Armstrong, C.1
Jorgensen, A.O.2
-
36
-
-
23844456403
-
Abnormal ryanodine receptor function in heart failure (Review)
-
Yano M, Yamamoto T, Ikemoto N, Matsuzaki M. Abnormal ryanodine receptor function in heart failure (Review). Pharmacol Ther 2005; 107: 377-391.
-
(2005)
Pharmacol Ther
, vol.107
, pp. 377-391
-
-
Yano, M.1
Yamamoto, T.2
Ikemoto, N.3
Matsuzaki, M.4
-
37
-
-
0030770826
-
Complex formation between junctin, triadin, calsequestrin, and the ryanodine receptor: Proteins of the cardiac junctional sarcoplasmic reticulum membrane
-
Zhang L, Kelley J, Schmeisser G, Kobayashi YM, Jones LR. Complex formation between junctin, triadin, calsequestrin, and the ryanodine receptor: Proteins of the cardiac junctional sarcoplasmic reticulum membrane. J Biol Chem 1997; 272: 23389-23397.
-
(1997)
J Biol Chem
, vol.272
, pp. 23389-23397
-
-
Zhang, L.1
Kelley, J.2
Schmeisser, G.3
Kobayashi, Y.M.4
Jones, L.R.5
-
38
-
-
0034973680
-
Ryanodine receptors/calcium release channels in heart failure and sudden cardiac death (Review)
-
Marks AR. Ryanodine receptors/calcium release channels in heart failure and sudden cardiac death (Review). J Mol Cell Cardiol 2001; 33: 615-624.
-
(2001)
J Mol Cell Cardiol
, vol.33
, pp. 615-624
-
-
Marks, A.R.1
-
39
-
-
26244467287
-
Phosphodiesterase 4D deficiency in the ryanodine-receptor complex promotes heart failure and arrhythmias
-
Lehnart SE, Wehrens XH, Reiken S, Warrier S, Belevych AE, Harvey RD, et al. Phosphodiesterase 4D deficiency in the ryanodine-receptor complex promotes heart failure and arrhythmias. Cell 2005; 123: 25-35.
-
(2005)
Cell
, vol.123
, pp. 25-35
-
-
Lehnart, S.E.1
Wehrens, X.H.2
Reiken, S.3
Warrier, S.4
Belevych, A.E.5
Harvey, R.D.6
-
40
-
-
0037133555
-
Propranolol prevents the development of heart failure by restoring FKBP12.6-mediated stabilization of ryanodine receptor
-
Doi M, Yano M, Kobayashi S, Kohno M, Tokuhisa T, Okuda S, et al. Propranolol prevents the development of heart failure by restoring FKBP12.6-mediated stabilization of ryanodine receptor. Circulation 2002; 105: 1374-1379.
-
(2002)
Circulation
, vol.105
, pp. 1374-1379
-
-
Doi, M.1
Yano, M.2
Kobayashi, S.3
Kohno, M.4
Tokuhisa, T.5
Okuda, S.6
-
41
-
-
1542373630
-
2+-release channel (ryanodine receptor) does not dissociate 12.6-kDa FK506-binding protein (FKBP12.6)
-
2+-release channel (ryanodine receptor) does not dissociate 12.6-kDa FK506-binding protein (FKBP12.6). Circ Res 2004; 94: 487-495.
-
(2004)
Circ Res
, vol.94
, pp. 487-495
-
-
Xiao, B.1
Sutherland, C.2
Walsh, M.P.3
Chen, S.R.4
-
42
-
-
0345803003
-
Characterization of recombinant skeletal muscle (Ser-2843) and cardiac muscle (Ser-2809) ryanodine receptor phosphorylation mutants
-
Stange M, Xu L, Balshaw D, Yamaguchi N, Meissner G. Characterization of recombinant skeletal muscle (Ser-2843) and cardiac muscle (Ser-2809) ryanodine receptor phosphorylation mutants. J Biol Chem 2003; 278: 51693-51702.
-
(2003)
J Biol Chem
, vol.278
, pp. 51693-51702
-
-
Stange, M.1
Xu, L.2
Balshaw, D.3
Yamaguchi, N.4
Meissner, G.5
-
43
-
-
33646771721
-
Ser-2030, but not Ser-2808, is the major phosphorylation site in cardiac ryanodine receptors responding to protein kinase A activation upon beta-adrenergic stimulation in normal and failing hearts
-
Xiao B, Zhong G, Obayashi M, Yang D, Chen K, Walsh MP, et al. Ser-2030, but not Ser-2808, is the major phosphorylation site in cardiac ryanodine receptors responding to protein kinase A activation upon beta-adrenergic stimulation in normal and failing hearts. Biochem J 2006; 396: 7-16.
-
(2006)
Biochem J
, vol.396
, pp. 7-16
-
-
Xiao, B.1
Zhong, G.2
Obayashi, M.3
Yang, D.4
Chen, K.5
Walsh, M.P.6
-
46
-
-
31444432542
-
Ryanodine receptor/calcium elease channel PKA phosphorylation: A critical mediator of heart failure progression
-
Wehrens XH, Lehnart SE, Reiken S, Vest JA, Wronska A, Marks AR. Ryanodine receptor/calcium elease channel PKA phosphorylation: A critical mediator of heart failure progression. Proc Natl Acad Sci USA 2006; 103: 511-518.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 511-518
-
-
Wehrens, X.H.1
Lehnart, S.E.2
Reiken, S.3
Vest, J.A.4
Wronska, A.5
Marks, A.R.6
-
47
-
-
35448984962
-
Intact beta-adrenergic response and unmodified progression toward heart failure in mice with genetic ablation of a major protein kinase A phosphorylation site in the cardiac ryanodine receptor
-
Benkusky NA, Weber CS, Scherman JA, Farrell EF, Hacker TA, John MC, et al. Intact beta-adrenergic response and unmodified progression toward heart failure in mice with genetic ablation of a major protein kinase A phosphorylation site in the cardiac ryanodine receptor. Circ Res 2007; 101: 819-829.
-
(2007)
Circ Res
, vol.101
, pp. 819-829
-
-
Benkusky, N.A.1
Weber, C.S.2
Scherman, J.A.3
Farrell, E.F.4
Hacker, T.A.5
John, M.C.6
-
48
-
-
35449001639
-
Regulation of ryanodine receptors in the heart
-
Lehnart S, Marks AR. Regulation of ryanodine receptors in the heart. Circ Res 2007; 101: 746-749.
-
(2007)
Circ Res
, vol.101
, pp. 746-749
-
-
Lehnart, S.1
Marks, A.R.2
-
49
-
-
0038643573
-
The deltaC isoform of CaMKII is activated in cardiac hypertrophy and induces dilated cardiomyopathy and heart failure
-
Zhang T, Maier LS, Dalton ND, Miyamoto S, Ross J Jr, Bers DM, et al. The deltaC isoform of CaMKII is activated in cardiac hypertrophy and induces dilated cardiomyopathy and heart failure. Circ Res 2003; 92: 912-919.
-
(2003)
Circ Res
, vol.92
, pp. 912-919
-
-
Zhang, T.1
Maier, L.S.2
Dalton, N.D.3
Miyamoto, S.4
Ross Jr, J.5
Bers, D.M.6
-
51
-
-
0037155056
-
Protein kinase A phos-phorylation of the ryanodine receptor does not affect calcium sparks in mouse ventricular myocytes
-
Li Y, Kranias EG, Mignery GA, Bers DM. Protein kinase A phos-phorylation of the ryanodine receptor does not affect calcium sparks in mouse ventricular myocytes. Circ Res 2002; 90: 309-316.
-
(2002)
Circ Res
, vol.90
, pp. 309-316
-
-
Li, Y.1
Kranias, E.G.2
Mignery, G.A.3
Bers, D.M.4
-
52
-
-
33747431210
-
2+/calmodulin-dependent protein kinase II phosphorylation of ryanodine receptor does affect calcium sparks in mouse ventricular myocytes
-
2+/calmodulin-dependent protein kinase II phosphorylation of ryanodine receptor does affect calcium sparks in mouse ventricular myocytes. Circ Res 2006; 99: 398-406.
-
(2006)
Circ Res
, vol.99
, pp. 398-406
-
-
Guo, T.1
Zhang, T.2
Mestril, R.3
Bers, D.M.4
-
54
-
-
0035907337
-
FKBP12 binding modulates ryanodine receptor channel gating
-
Gaburjakova M, Gaburjakova J, Reiken S, Huang F, Marx SO, Rosemblit N, et al. FKBP12 binding modulates ryanodine receptor channel gating. J Biol Chem 2001; 276: 16931-16935.
-
(2001)
J Biol Chem
, vol.276
, pp. 16931-16935
-
-
Gaburjakova, M.1
Gaburjakova, J.2
Reiken, S.3
Huang, F.4
Marx, S.O.5
Rosemblit, N.6
-
56
-
-
0037853208
-
Three-dimensional localization of divergent region 3 of the ryanodine receptor to the clamp-shaped structures adjacent to the FKBP binding sites
-
Zhang J, Liu Z, Masumiya H, Wang R, Jiang D, Li F, et al. Three-dimensional localization of divergent region 3 of the ryanodine receptor to the clamp-shaped structures adjacent to the FKBP binding sites. J Biol Chem 2003; 278: 14211-14218.
-
(2003)
J Biol Chem
, vol.278
, pp. 14211-14218
-
-
Zhang, J.1
Liu, Z.2
Masumiya, H.3
Wang, R.4
Jiang, D.5
Li, F.6
-
57
-
-
14044276304
-
Interaction of FKBP12.6 with the cardiac ryanodine receptor C-terminal domain
-
Zissimopoulos S, Lai FA. Interaction of FKBP12.6 with the cardiac ryanodine receptor C-terminal domain. J Biol Chem 2005; 280: 5475-5485.
-
(2005)
J Biol Chem
, vol.280
, pp. 5475-5485
-
-
Zissimopoulos, S.1
Lai, F.A.2
-
58
-
-
34548483659
-
Three-dimensional localization of serine 2808, a phosphorylation site in cardiac ryanodine receptor
-
Meng X, Xiao B, Cai S, Huang X, Li F, Bolstad J, et al. Three-dimensional localization of serine 2808, a phosphorylation site in cardiac ryanodine receptor. J Biol Chem 2007; 282: 25929-25939.
-
(2007)
J Biol Chem
, vol.282
, pp. 25929-25939
-
-
Meng, X.1
Xiao, B.2
Cai, S.3
Huang, X.4
Li, F.5
Bolstad, J.6
-
59
-
-
0035895322
-
Mutations in the cardiac ryanodine receptor gene (hRyR2) underlie catecholaminergic polymorphic ventricular tachycardia
-
Priori SG, Napolitano C, Tiso N, Memmi M, Vignati G, Bloise R, et al. Mutations in the cardiac ryanodine receptor gene (hRyR2) underlie catecholaminergic polymorphic ventricular tachycardia. Circulation 2001; 103: 196-200.
-
(2001)
Circulation
, vol.103
, pp. 196-200
-
-
Priori, S.G.1
Napolitano, C.2
Tiso, N.3
Memmi, M.4
Vignati, G.5
Bloise, R.6
-
60
-
-
0035969990
-
Mutations of the cardiac ryanodine receptor (RyR2) gene in familial polymorphic ventricular tachycardia
-
Laitinen PJ, Brown KM, Piippo K, Swan H, Devaney JM, Brahmbhatt B, et al. Mutations of the cardiac ryanodine receptor (RyR2) gene in familial polymorphic ventricular tachycardia. Circulation 2001; 103: 485-490.
-
(2001)
Circulation
, vol.103
, pp. 485-490
-
-
Laitinen, P.J.1
Brown, K.M.2
Piippo, K.3
Swan, H.4
Devaney, J.M.5
Brahmbhatt, B.6
-
61
-
-
0035253502
-
Identification of mutations in the cardiac ryanodine receptor gene in families affected with arrhythmogenic right ventricular cardiomyopathy type 2 (ARVD2)
-
Tiso N, Stephan DA, Nava A, Bagattin A, Devaney JM, Stanchi F, et al. Identification of mutations in the cardiac ryanodine receptor gene in families affected with arrhythmogenic right ventricular cardiomyopathy type 2 (ARVD2). Hum Mol Genet 2001; 10: 189-194.
-
(2001)
Hum Mol Genet
, vol.10
, pp. 189-194
-
-
Tiso, N.1
Stephan, D.A.2
Nava, A.3
Bagattin, A.4
Devaney, J.M.5
Stanchi, F.6
-
62
-
-
0036514152
-
Regulation of calcium release by interdomain interaction within ryanodine receptors
-
Ikemoto N, Yamamoto T. Regulation of calcium release by interdomain interaction within ryanodine receptors. Front Biosci 2002; 7: d671-d683.
-
(2002)
Front Biosci
, vol.7
-
-
Ikemoto, N.1
Yamamoto, T.2
-
63
-
-
0036291245
-
Peptide probe study of the critical regulatory domain of the cardiac ryanodine receptor
-
Yamamoto T, Ikemoto N. Peptide probe study of the critical regulatory domain of the cardiac ryanodine receptor. Biochem Biophys Res Commun 2002; 291: 1102-1108.
-
(2002)
Biochem Biophys Res Commun
, vol.291
, pp. 1102-1108
-
-
Yamamoto, T.1
Ikemoto, N.2
-
64
-
-
27844535779
-
Localization of a disease-associated mutation site in the three-dimensional structure of the cardiac muscle ryanodine receptor
-
Liu Z, Wang R, Zhang J, Chen SR, Wagenknecht T. Localization of a disease-associated mutation site in the three-dimensional structure of the cardiac muscle ryanodine receptor. J Biol Chem 2005; 280: 37941-37947.
-
(2005)
J Biol Chem
, vol.280
, pp. 37941-37947
-
-
Liu, Z.1
Wang, R.2
Zhang, J.3
Chen, S.R.4
Wagenknecht, T.5
-
65
-
-
21544451389
-
Defective regulation of interdomain interactions within the ryanodine receptor plays a key role in the pathogenesis of heart failure
-
Oda T, Yano M, Yamamoto T, Tokuhisa T, Okuda S, Doi M, et al. Defective regulation of interdomain interactions within the ryanodine receptor plays a key role in the pathogenesis of heart failure. Circulation 2005; 111: 3400-3410.
-
(2005)
Circulation
, vol.111
, pp. 3400-3410
-
-
Oda, T.1
Yano, M.2
Yamamoto, T.3
Tokuhisa, T.4
Okuda, S.5
Doi, M.6
-
67
-
-
4444252601
-
Functional heterogeneity of ryanodine receptor mutations associated with sudden cardiac death
-
Thomas NL, George CH, Lai FA. Functional heterogeneity of ryanodine receptor mutations associated with sudden cardiac death. Cardiovasc Res 2004; 64: 52-60.
-
(2004)
Cardiovasc Res
, vol.64
, pp. 52-60
-
-
Thomas, N.L.1
George, C.H.2
Lai, F.A.3
-
68
-
-
0023818533
-
2+ binding effects on protein conformation and protein interactions of canine cardiac calsequestrin
-
2+ binding effects on protein conformation and protein interactions of canine cardiac calsequestrin. J Biol Chem 1988; 263: 1376-1381.
-
(1988)
J Biol Chem
, vol.263
, pp. 1376-1381
-
-
Mitchell, R.D.1
Simmerman, H.K.2
Jones, L.R.3
-
69
-
-
1942423621
-
The role of calsequestrin, triadin, and junctin in conferring cardiac ryanodine receptor responsiveness to luminal calcium
-
Györke I, Hester N, Jones LR, Györke S. The role of calsequestrin, triadin, and junctin in conferring cardiac ryanodine receptor responsiveness to luminal calcium. Biophys J 2004; 86: 2121-2128.
-
(2004)
Biophys J
, vol.86
, pp. 2121-2128
-
-
Györke, I.1
Hester, N.2
Jones, L.R.3
Györke, S.4
-
70
-
-
2442657710
-
A missense mutation in CASQ2 is associated with autosomal recessive catecholamine-induced polymorphic ventricular tachycardia in Bedouin families from Israel
-
Lahat H, Pras E, Eldar M. A missense mutation in CASQ2 is associated with autosomal recessive catecholamine-induced polymorphic ventricular tachycardia in Bedouin families from Israel. Ann Med 2004; 36: 87-91.
-
(2004)
Ann Med
, vol.36
, pp. 87-91
-
-
Lahat, H.1
Pras, E.2
Eldar, M.3
-
71
-
-
33745032863
-
Abnormal interactions of calsequestrin with the ryanodine receptor calcium release channel complex linked to exercise-induced sudden cardiac death
-
Terentyev D, Nori A, Santoro M, Viatchenko-Karpinski S, Kubalova Z, Gyorke I, et al. Abnormal interactions of calsequestrin with the ryanodine receptor calcium release channel complex linked to exercise-induced sudden cardiac death. Circ Res 2006; 98: 1151-1158.
-
(2006)
Circ Res
, vol.98
, pp. 1151-1158
-
-
Terentyev, D.1
Nori, A.2
Santoro, M.3
Viatchenko-Karpinski, S.4
Kubalova, Z.5
Gyorke, I.6
-
72
-
-
33748512585
-
Clinical phenotype and functional characterization of CASQ2 mutations associated with catecholaminergic polymorphic ventricular tachycardia
-
di Barletta MR, Viatchenko-Karpinski S, Nori A, Memmi M, Terentyev D, Turcato F, et al. Clinical phenotype and functional characterization of CASQ2 mutations associated with catecholaminergic polymorphic ventricular tachycardia. Circulation 2006; 114: 1012-1019.
-
(2006)
Circulation
, vol.114
, pp. 1012-1019
-
-
di Barletta, M.R.1
Viatchenko-Karpinski, S.2
Nori, A.3
Memmi, M.4
Terentyev, D.5
Turcato, F.6
-
73
-
-
0037131020
-
Absence of calsequestrin 2 causes severe forms of catecholaminergic polymorphic ventricular tachycardia
-
Postma AV, Denjoy I, Hoorntje TM, Lupoglazoff JM, Da Costa A, Sebillon P, et al. Absence of calsequestrin 2 causes severe forms of catecholaminergic polymorphic ventricular tachycardia. Circ Res 2002; 91: e21-e26.
-
(2002)
Circ Res
, vol.91
-
-
Postma, A.V.1
Denjoy, I.2
Hoorntje, T.M.3
Lupoglazoff, J.M.4
Da Costa, A.5
Sebillon, P.6
-
74
-
-
33748292955
-
2+ release, and catecholaminergic polymorphic ventricular tachycardia
-
2+ release, and catecholaminergic polymorphic ventricular tachycardia. J Clin Invest 2006; 116: 2510-2520.
-
(2006)
J Clin Invest
, vol.116
, pp. 2510-2520
-
-
Knollmann, B.C.1
Chopra, N.2
Hlaing, T.3
Akin, B.4
Yang, T.5
Ettensohn, K.6
-
75
-
-
34447133403
-
Calsequestrin 2 (CASQ2) mutations increase expression of calreticulin and ryanodine receptors, causing catecholaminergic polymorphic ventricular tachycardia
-
Song L, Alcalai R, Arad M, Wolf CM, Toka O, Conner DA, et al. Calsequestrin 2 (CASQ2) mutations increase expression of calreticulin and ryanodine receptors, causing catecholaminergic polymorphic ventricular tachycardia. J Clin Invest 2007; 117: 1814-1823.
-
(2007)
J Clin Invest
, vol.117
, pp. 1814-1823
-
-
Song, L.1
Alcalai, R.2
Arad, M.3
Wolf, C.M.4
Toka, O.5
Conner, D.A.6
-
77
-
-
0037162348
-
Rate dependence of [Na+]i and contractility in nonfailing and failing human myocardium
-
Pieske B, Maier LS, Piacentino V 3rd, Weisser J, Hasenfuss G, Houser S. Rate dependence of [Na+]i and contractility in nonfailing and failing human myocardium. Circulation 2002; 106: 447-453.
-
(2002)
Circulation
, vol.106
, pp. 447-453
-
-
Pieske, B.1
Maier, L.S.2
Piacentino 3rd, V.3
Weisser, J.4
Hasenfuss, G.5
Houser, S.6
-
78
-
-
0037188622
-
Intracellular Na(+) concentration is elevated in heart failure but Na/K pump function is unchanged
-
Despa S, Islam MA, Weber CR, Pogwizd SM, Bers DM. Intracellular Na(+) concentration is elevated in heart failure but Na/K pump function is unchanged. Circulation 2002; 105: 2543-2548.
-
(2002)
Circulation
, vol.105
, pp. 2543-2548
-
-
Despa, S.1
Islam, M.A.2
Weber, C.R.3
Pogwizd, S.M.4
Bers, D.M.5
-
79
-
-
0037376584
-
Na+]i handling in the failing human heart (Review)
-
Pieske B, Houser SR. [Na+]i handling in the failing human heart (Review). Cardiovasc Res 2003; 57: 874-886.
-
(2003)
Cardiovasc Res
, vol.57
, pp. 874-886
-
-
Pieske, B.1
Houser, S.R.2
-
80
-
-
85047680836
-
Calcium uptake by cardiac sarcoplasmic reticulum in human dilated cardiomyopathy
-
Limas CJ, Olivari MT, Goldenberg IF, Levine TB, Benditt DG, Simon A. Calcium uptake by cardiac sarcoplasmic reticulum in human dilated cardiomyopathy. Cardiovasc Res 1987; 21: 601-605.
-
(1987)
Cardiovasc Res
, vol.21
, pp. 601-605
-
-
Limas, C.J.1
Olivari, M.T.2
Goldenberg, I.F.3
Levine, T.B.4
Benditt, D.G.5
Simon, A.6
-
82
-
-
0036164778
-
Reduced level of serine16 phosphorylated phospholamban in the failing rat myocardium: A major contributor to reduced SERCA2 activity
-
Sande JB, Sjaastad I, Hoen IB, Bokenes J, Tonnessen T, Holt E, et al. Reduced level of serine16 phosphorylated phospholamban in the failing rat myocardium: A major contributor to reduced SERCA2 activity. Cardiovasc Res 2002; 53: 382-391.
-
(2002)
Cardiovasc Res
, vol.53
, pp. 382-391
-
-
Sande, J.B.1
Sjaastad, I.2
Hoen, I.B.3
Bokenes, J.4
Tonnessen, T.5
Holt, E.6
-
83
-
-
85047679474
-
cAMP concentrations, cAMP dependent protein kinase activity, and phospholamban in non-failing and failing myocardium
-
Bohm M, Reiger B, Schwinger RH, Erdmann E. cAMP concentrations, cAMP dependent protein kinase activity, and phospholamban in non-failing and failing myocardium. Cardiovasc Res 1994; 28: 1713-1719.
-
(1994)
Cardiovasc Res
, vol.28
, pp. 1713-1719
-
-
Bohm, M.1
Reiger, B.2
Schwinger, R.H.3
Erdmann, E.4
-
86
-
-
0030888810
-
Increased expression of cardiac phosphatases in patients with end-stage heart failure
-
Neumann J, Eschenhagen T, Jones LR, Linck B, Schmitz W, Scholz H, et al. Increased expression of cardiac phosphatases in patients with end-stage heart failure. J Mol Cell Cardiol 1997; 29: 265-272.
-
(1997)
J Mol Cell Cardiol
, vol.29
, pp. 265-272
-
-
Neumann, J.1
Eschenhagen, T.2
Jones, L.R.3
Linck, B.4
Schmitz, W.5
Scholz, H.6
-
87
-
-
0032724685
-
Diminished basal phosphorylation level of phospholamban in the postinfarction remodeled rat ventricle: Role of beta-adrenergic pathway, G(i) protein, phosphodiesterase, and phosphatases
-
Huang B, Wang S, Qin D, Boutjdir M, El-Sherif N. Diminished basal phosphorylation level of phospholamban in the postinfarction remodeled rat ventricle: Role of beta-adrenergic pathway, G(i) protein, phosphodiesterase, and phosphatases. Circ Res 1999; 85: 848-855.
-
(1999)
Circ Res
, vol.85
, pp. 848-855
-
-
Huang, B.1
Wang, S.2
Qin, D.3
Boutjdir, M.4
El-Sherif, N.5
-
88
-
-
0344009618
-
Cardiac SR-coupled PP1 activity and expression are increased and inhibitor 1 protein expression is decreased in failing hearts
-
Gupta RC, Mishra S, Rastogi S, Imai M, Habib O, Sabbah HN. Cardiac SR-coupled PP1 activity and expression are increased and inhibitor 1 protein expression is decreased in failing hearts. Am J Physiol Heart Circ Physiol 2003; 285: H2373-H2381.
-
(2003)
Am J Physiol Heart Circ Physiol
, vol.285
-
-
Gupta, R.C.1
Mishra, S.2
Rastogi, S.3
Imai, M.4
Habib, O.5
Sabbah, H.N.6
-
89
-
-
14244249503
-
Reduced inhibitor 1 and 2 activity is associated with increased protein phosphatase type 1 activity in left ventricular myocardium of one-kidney, one-clip hypertensive rats
-
Gupta RC, Mishra S, Yang XP, Sabbah HN. Reduced inhibitor 1 and 2 activity is associated with increased protein phosphatase type 1 activity in left ventricular myocardium of one-kidney, one-clip hypertensive rats. Mol Cell Biochem 2005; 269: 49-57.
-
(2005)
Mol Cell Biochem
, vol.269
, pp. 49-57
-
-
Gupta, R.C.1
Mishra, S.2
Yang, X.P.3
Sabbah, H.N.4
-
90
-
-
0036261564
-
Type 1 phosphatase, a negative regulator of cardiac function
-
Carr AN, Schmidt AG, Suzuki Y, del Monte F, Sato Y, Lanner C, et al. Type 1 phosphatase, a negative regulator of cardiac function. Mol Cell Biol 2002; 22: 4124-4135.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 4124-4135
-
-
Carr, A.N.1
Schmidt, A.G.2
Suzuki, Y.3
del Monte, F.4
Sato, Y.5
Lanner, C.6
-
91
-
-
0347357650
-
Decreased protein and phosphorylation level of the protein phosphatase inhibitor-1 in failing human hearts
-
El-Armouche A, Pamminger T, Ditz D, Zolk O, Eschenhagen T. Decreased protein and phosphorylation level of the protein phosphatase inhibitor-1 in failing human hearts. Cardiovasc Res 2004; 61: 87-93.
-
(2004)
Cardiovasc Res
, vol.61
, pp. 87-93
-
-
El-Armouche, A.1
Pamminger, T.2
Ditz, D.3
Zolk, O.4
Eschenhagen, T.5
-
92
-
-
33845611066
-
Inhibition of protein phosphatase 1 by inhibitor-2 gene delivery ameliorates heart failure progression in genetic cardiomyopathy
-
Yamada M, Ikeda Y, Yano M, Yoshimura K, Nishino S, Aoyama H, et al. Inhibition of protein phosphatase 1 by inhibitor-2 gene delivery ameliorates heart failure progression in genetic cardiomyopathy. Faseb J 2006; 20: 1197-1199.
-
(2006)
Faseb J
, vol.20
, pp. 1197-1199
-
-
Yamada, M.1
Ikeda, Y.2
Yano, M.3
Yoshimura, K.4
Nishino, S.5
Aoyama, H.6
-
93
-
-
0035662009
-
Enhanced PKCβ II translocation and PKC-β II-RACK1 interactions in PKCe-induced heart failure: A role for RACK1
-
Pass JM, Gao J, Jones WK, Wead WB, Wu X, Zhang J, et al. Enhanced PKCβ II translocation and PKC-β II-RACK1 interactions in PKCe-induced heart failure: A role for RACK1. Am J Physiol 2001; 281: H2500-H2510.
-
(2001)
Am J Physiol
, vol.281
-
-
Pass, J.M.1
Gao, J.2
Jones, W.K.3
Wead, W.B.4
Wu, X.5
Zhang, J.6
-
94
-
-
1642388834
-
PKC-alpha regulates cardiac contractility and propensity toward heart failure
-
Braz JC, Gregory K, Pathak A, Zhao W, Sahin B, Klevitsky R, et al. PKC-alpha regulates cardiac contractility and propensity toward heart failure. Nat Med 2004; 10: 248-254.
-
(2004)
Nat Med
, vol.10
, pp. 248-254
-
-
Braz, J.C.1
Gregory, K.2
Pathak, A.3
Zhao, W.4
Sahin, B.5
Klevitsky, R.6
-
95
-
-
0038662725
-
Beta-blockers restore calcium release channel function and improve cardiac muscle performance in human heart failure
-
Reiken S, Wehrens XH, Vest JA, Barbone A, Klotz S, Mancini D, et al. Beta-blockers restore calcium release channel function and improve cardiac muscle performance in human heart failure. Circulation 2003; 107: 2459-2466.
-
(2003)
Circulation
, vol.107
, pp. 2459-2466
-
-
Reiken, S.1
Wehrens, X.H.2
Vest, J.A.3
Barbone, A.4
Klotz, S.5
Mancini, D.6
-
96
-
-
10744228679
-
Valsartan restores sarcoplasmic reticulum function with no appreciable effect on resting cardiac function in pacing-induced heart failure
-
Okuda S, Yano M, Doi M, Oda T, Tokuhisa T, Kohno M, et al. Valsartan restores sarcoplasmic reticulum function with no appreciable effect on resting cardiac function in pacing-induced heart failure. Circulation 2004; 109: 911-919.
-
(2004)
Circulation
, vol.109
, pp. 911-919
-
-
Okuda, S.1
Yano, M.2
Doi, M.3
Oda, T.4
Tokuhisa, T.5
Kohno, M.6
-
97
-
-
0037469180
-
FKBP12.6-mediated stabilization of calcium-release channel (ryanodine receptor) as a novel therapeutic strategy against heart failure
-
Yano M, Kobayashi S, Kohno M, Doi M, Tokuhisa T, Okuda S, et al. FKBP12.6-mediated stabilization of calcium-release channel (ryanodine receptor) as a novel therapeutic strategy against heart failure. Circulation 2003; 107: 477-484.
-
(2003)
Circulation
, vol.107
, pp. 477-484
-
-
Yano, M.1
Kobayashi, S.2
Kohno, M.3
Doi, M.4
Tokuhisa, T.5
Okuda, S.6
-
98
-
-
1842482414
-
Protection from cardiac arrhythmia through ryanodine receptor-stabilizing protein calstabin2
-
Wehrens XH, Lehnart SE, Reiken SR, Deng SX, Vest JA, Cervantes D, et al. Protection from cardiac arrhythmia through ryanodine receptor-stabilizing protein calstabin2. Science 2004; 304: 292-296.
-
(2004)
Science
, vol.304
, pp. 292-296
-
-
Wehrens, X.H.1
Lehnart, S.E.2
Reiken, S.R.3
Deng, S.X.4
Vest, J.A.5
Cervantes, D.6
-
99
-
-
39549096684
-
Identification of target domains of the cardiac ryanodine receptor to correct channel disorder in failing hearts
-
Yamamoto T, Yano M, Xu X, Uchinoumi H, Tateishi H, Mochizuki M, et al. Identification of target domains of the cardiac ryanodine receptor to correct channel disorder in failing hearts. Circulation 2008; 117: 762-772.
-
(2008)
Circulation
, vol.117
, pp. 762-772
-
-
Yamamoto, T.1
Yano, M.2
Xu, X.3
Uchinoumi, H.4
Tateishi, H.5
Mochizuki, M.6
-
100
-
-
33746788063
-
Arrhythmogenesis in catecholaminergic polymorphic ventricular tachycardia: Insights from a RyR2 R4496C knock-in mouse model
-
Liu N, Colombi B, Memmi M, Zissimopoulos S, Rizzi N, Negri S, et al. Arrhythmogenesis in catecholaminergic polymorphic ventricular tachycardia: Insights from a RyR2 R4496C knock-in mouse model. Circ Res 2006; 99: 292-298.
-
(2006)
Circ Res
, vol.99
, pp. 292-298
-
-
Liu, N.1
Colombi, B.2
Memmi, M.3
Zissimopoulos, S.4
Rizzi, N.5
Negri, S.6
-
101
-
-
33644877287
-
Correction of defective interdomain interaction within ryanodine receptor by antioxidant is a new therapeutic strategy against heart failure
-
Yano M, Okuda S, Oda T, Tokuhisa T, Tateishi H, Mochizuki M, et al. Correction of defective interdomain interaction within ryanodine receptor by antioxidant is a new therapeutic strategy against heart failure. Circulation 2005; 112: 3633-3643.
-
(2005)
Circulation
, vol.112
, pp. 3633-3643
-
-
Yano, M.1
Okuda, S.2
Oda, T.3
Tokuhisa, T.4
Tateishi, H.5
Mochizuki, M.6
-
103
-
-
12944332074
-
Adenoviral gene transfer of SERCA2a improves left-ventricular function in aortic-banded rats in transition to heart failure
-
Miyamoto MI, del Monte F, Schmidt U, DiSalvo TS, Kang ZB, Matsui T, et al. Adenoviral gene transfer of SERCA2a improves left-ventricular function in aortic-banded rats in transition to heart failure. Proc Natl Acad Sci USA 2000; 97: 793-798.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 793-798
-
-
Miyamoto, M.I.1
del Monte, F.2
Schmidt, U.3
DiSalvo, T.S.4
Kang, Z.B.5
Matsui, T.6
-
108
-
-
52949148660
-
-
Calcium Up-Regulation by Percutaneous Administration of Gene Therapy In Cardiac Disease (CUPID Trial) http://www.celladon.net http://www.celladon.net/ press_may1707.php
-
Calcium Up-Regulation by Percutaneous Administration of Gene Therapy In Cardiac Disease (CUPID Trial) http://www.celladon.net http://www.celladon.net/ press_may1707.php
-
-
-
-
109
-
-
0033615645
-
Chronic phospholamban-sarcoplasmic reticulum calcium ATPase interaction is the critical calcium cycling defect in dilated cardio-myopathy
-
Minamisawa S, Hoshijima M, Chu G, Ward CA, Frank K, Gu Y, et al. Chronic phospholamban-sarcoplasmic reticulum calcium ATPase interaction is the critical calcium cycling defect in dilated cardio-myopathy. Cell 1999; 99: 313-322.
-
(1999)
Cell
, vol.99
, pp. 313-322
-
-
Minamisawa, S.1
Hoshijima, M.2
Chu, G.3
Ward, C.A.4
Frank, K.5
Gu, Y.6
-
110
-
-
0036341380
-
Chronic suppression of heart-failure progression by a pseudo-phosphorylated mutant of phospholamban via in vivo cardiac rAAV gene delivery
-
Hoshijima M, Ikeda Y, Iwanaga Y, Minamisawa S, Date MO, Gu Y, et al. Chronic suppression of heart-failure progression by a pseudo-phosphorylated mutant of phospholamban via in vivo cardiac rAAV gene delivery. Nat Med 2002; 8: 864-871.
-
(2002)
Nat Med
, vol.8
, pp. 864-871
-
-
Hoshijima, M.1
Ikeda, Y.2
Iwanaga, Y.3
Minamisawa, S.4
Date, M.O.5
Gu, Y.6
-
111
-
-
85047689989
-
Chronic phospholamban inhibition prevents progressive cardiac dysfunction and pathological remodeling after infarction in rats
-
Iwanaga Y, Hoshijima M, Gu Y, Iwatate M, Dieterle T, Ikeda Y, et al. Chronic phospholamban inhibition prevents progressive cardiac dysfunction and pathological remodeling after infarction in rats. J Clin Invest 2004; 113: 727-736.
-
(2004)
J Clin Invest
, vol.113
, pp. 727-736
-
-
Iwanaga, Y.1
Hoshijima, M.2
Gu, Y.3
Iwatate, M.4
Dieterle, T.5
Ikeda, Y.6
-
112
-
-
0012300264
-
Re-evaluating sarcoplasmic reticulum function in heart failure
-
Delling U, Sussman MA, Molkentin JD. Re-evaluating sarcoplasmic reticulum function in heart failure. Nat Med 2000; 6: 942-943.
-
(2000)
Nat Med
, vol.6
, pp. 942-943
-
-
Delling, U.1
Sussman, M.A.2
Molkentin, J.D.3
-
113
-
-
0037362850
-
Rescue of cardiomyocyte dysfunction by phospholamban ablation does not prevent ventricular failure in genetic hypertrophy
-
Song Q, Schmidt AG, Hahn HS, Carr AN, Frank B, Pater L, et al. Rescue of cardiomyocyte dysfunction by phospholamban ablation does not prevent ventricular failure in genetic hypertrophy. J Clin Invest 2003; 111: 859-867.
-
(2003)
J Clin Invest
, vol.111
, pp. 859-867
-
-
Song, Q.1
Schmidt, A.G.2
Hahn, H.S.3
Carr, A.N.4
Frank, B.5
Pater, L.6
-
114
-
-
24344499138
-
Enhanced cardiac function in mice overexpressing protein phosphatase Inhibitor-2
-
Kirchhefer U, Baba HA, Boknik P, Breeden KM, Mavila N, Bruchert N, et al. Enhanced cardiac function in mice overexpressing protein phosphatase Inhibitor-2. Cardiovasc Res 2005; 68: 98-108.
-
(2005)
Cardiovasc Res
, vol.68
, pp. 98-108
-
-
Kirchhefer, U.1
Baba, H.A.2
Boknik, P.3
Breeden, K.M.4
Mavila, N.5
Bruchert, N.6
|