Integrated Ca2+ management in cardiac myocytes

Annals of the New York Academy of Sciences

Volumn 1015, Issue , 2004, Pages 28-38

  Shannon, Thomas R ^a,b   Bers, Donald M ^a  

^a LOYOLA UNIVERSITY CHICAGO   (United States)

^b RUSH UNIVERSITY   (United States)

Author keywords

Ca cycling; Excitation contraction coupling; Membrane transport; Ryanodine receptors; Sarcoplasmic reticulum

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); CALCIUM ION; SODIUM CALCIUM EXCHANGE PROTEIN; CALCIUM;

CALCIUM CURRENT; CALCIUM HOMEOSTASIS; CALCIUM TRANSPORT; CONFERENCE PAPER; CYTOSOL; DIASTOLE; EXCITATION CONTRACTION COUPLING; HEART ARRHYTHMIA; HEART FAILURE; HEART FUNCTION; HEART MUSCLE CELL; HUMAN; NONHUMAN; REGULATORY MECHANISM; SARCOLEMMA; SARCOPLASMIC RETICULUM; SYSTOLE; ANIMAL; CYTOLOGY; HEART MUSCLE; ION TRANSPORT; METABOLISM; NON-PROGRAMMATIC; REVIEW;

NON-PROGRAMMATIC;

ANIMALS; CALCIUM; ION TRANSPORT; MYOCARDIUM; SARCOPLASMIC RETICULUM;

EID: 3042711556     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1196/annals.1302.003     Document Type: Conference Paper

References (54)

1. BERS, D.M. 2001. Excitation-Contraction Coupling and Cardiac Contractile Force, 2nd edit.Kluwer Academic Publishers. Dordrecht.
2. BASSANI, J.W.M., R.A. BASSANI & D.M. BERS. 1994. Relaxation in rabbit and rat cardiac cells: species-dependent differences in cellular mechanisms. J. Physiol. 476: 279-293.
3. PIACENTINO, III, V., C.R. WEBER, X. CHEN, et al. 2003. Cellular basis of abnormal calcium transients of failing human ventricular myocytes. Circ. Res. 92: 651-658.
4. 2+. transient in rat ventricular myocytes. J. Physiol. 468: 35-52.
5. FEHER, J.J. & F.N. BRIGGS. 1984. Unidirectional calcium and nucleotide fluxes in sarcoplasmic reticulum. II. Experimental results. Biophys. J, 45: 1135-1144.
6. TAKENAKA, H., P.N. ADLER & A.M. KATZ. 1982. Calcium fluxes across the membrane of sarcoplasmic reticulum vesicles. J. Biol. Chem. 257: 12649-12656.
7. BALKE, C., W.T.M. EGAN & W.G. WIER. 1994. Processes that remove calcium from the cytoplasm during excitation-contraction coupling in intact rat heart cells. J. Physiol. 474: 447-462.
8. 2+ content and membrane current in isolated rat ventricular myocytes. J. Physiol. 507: 759-769.
9. BASSANI, J.W.M., W. YUAN & D.M. BERS. 1995. Fractional SR Ca release is regulated by trigger Ca and SR Ca content in cardiac myocytes. Am. J. Physiol. 268: 1313-1329.
10. GINSBURG, K.S., C.R. WEBER & D.M. BERS. 1998. Control of maximum sarcoplasmic reticulum Ca load in intact ferret ventricular myocytes: effects of thapsigargin and isoproternol. J. Gen. Physiol. 111: 491-504.
11. SHANNON, T.R. & D.M. BERS. 1997. Assessment of intra-SR free [Ca] and buffering in rat heart. Biophys. J. 73: 1524-1531.
12. SHANNON, T.R., K.S. GINSBURG & D.M. BERS. 2000. Reverse mode of the SR Ca-pump and load-dependent cytosolic Ca decline in voltage clamped cardiac ventricular myocytes. Biophys. J. 78: 322-333.
13. 2+ transport. Biochemistry 39: 14176-14182.
14. SHANNON, T., G. CHU, E. KRANIAS, et al. 2001. Phospholamban decreases the energetic efficiency of the sarcoplasmic reticulum Ca-pump. J. Biol. Chem. 276: 7195-7201.
15. BASSANI, R.A. & D.M. BERS. 1995. Rate of diastolic Ca release from the sarcoplasmic reticulum of intact rabbit and rat ventricular myocytes. Biophys. J. 68: 2015-2022.
16. 2+- sensitive leak in rat ventricular myocytes. Biophys. J. 81: 785-798.
17. GYRKE, S., V. LUKYANENKO & I. GYRKE. 1997. Dual effects of tetracaine on spontaneous calcium release in rat ventricular myocytes. J. Physiol. 500: 297-309.
18. OVEREND, C.L., D.A. EISNER & S.C. O'NEILL. 1997. The effect of tetracaine on spontaneous Ca2+ release and sarcoplasmic reticulum calcium content in rat ventricular myocytes. J. Physiol. 502: 471-479.
19. SHANNON, T.R., K.S. GINSBURG & D.M. BERS. 2002. Quantitative assessment of SR Ca leak-load relationships. Circ. Res. 91: 594-600.
20. 2+. J. Membrane Biol. 137: 215-226.
21. 2+. sensing sites. Biophys. J. 75: 2801-2810.
22. 2+ current in cardiac cells. Am. J. Physiol. 268: H916-H920.
23. SONG, L.S., M.D. STERN, E.G. LAKATTA, et al. 1997. Partial depletion of sarcoplasmic reticulum calcium does not prevent calcium sparks in rat ventricular myocytes. J. Physiol. 505: 665-675.
24. 2+ release by voltage-clamp pulse duration in potentiated guinea-pig ventricular myocytes. J. Physiol. 480: 423-438.
25. 2+ release involving ryanodine receptors. Mol. Pharmacol. 52: 1124-1130.
26. SANTANA, L.F., E.G. KRANIAS & W.J. LEDERER. 1997. Calcium sparks and excitation contraction coupling in phospholamban-deficient mouse ventricular myocytes. J. Physiol. 503: 21-29.
27. SPENCER, C.I. & J.R. BERLIN. 1995. Control of sarcoplasmic reticulum calcium release during calcium loading in isolated rat ventricular myocytes. J. Physiol. 488: 267-279.
28. SPENCER, C.I. & J.R. BERLIN. 1997. Calcium-induced release of strontium ions from the sarcoplasmic reticulum of rat cardiac ventricular myocytes. J. Physiol. 504: 565-578.
29. 2+]i-transients in phospholamban-deficient mouse ventricular cells. Am. J. Physiol. 274: H1800-H1811.
30. SHANNON, T.R., K.S. GINSBURG & D.M. BERS. 2000. Potentiation of fractional SR Ca release by total and free intra-SR Ca concentration. Biophys. J. 78: 334-343.
31. 2+ fluxes in rat ventricular myocytes. J. Physiol. 522: 259-270.
32. 2+ release causes myocyte depolarization, underlying mechanism and threshold for triggered action potentials. Circ. Res. 87: 774-780.
33. COLQUHOUN, D., E. NEHER, H. REUTER & C.F. STEVENS. 1981. Inward current channels activated by intracellular Ca in cultured cardiac cells. Nature 294: 752-754.
34. CANNELL, M.B. & W.J. LEDERER. 1986. The arrhythmogenic current ITI in the absence of electrogenic sodium-calcium exchange in sheep cardiac Purkinje fibres. J. Physiol. 374: 201-219.
35. FEDIDA, D., D. NOBLE, A.C. RANKIN & A.J. SPINDLER. 1987. The arrhythmogenic transient inward current Iti and related contraction in isolated guinea-pig ventricular myocytes. J. Physiol. 392: 523-542.
36. 2+.]i transients in single rabbit heart Purkinje cells. J. Physiol. 483: 319-330.
37. SHANNON, T.R., T. GUO & D.M. BERS. 2003. Ca scraps: local depletions of free [Ca] in cardiac sarcoplasmic reticulum during contractions leave substantial Ca reserve. Circ. Res. 93: 40-45.
38. CHENG, H,. W.J. LEDERER & M.B. CANNELL. 1993. Calcium sparks: elementary events underlying excitation-contraction coupling in heart muscle. Science 262: 740-744.
39. 2+ load, and rest on Ca2+ spark frequency in ventricular myocytes. Am. J. Physiol. 272: 657-668.
40. BERS, D.M. 2002. Cardiac excitation-contraction coupling. Nature 415: 198-205.
41. STERN, M.D. 1992. Theory of excitation-contraction coupling in cardiac muscle. Biophys. J. 63: 497-517.
42. 2+]i waves in cardiac myocytes. Am. J. Physiol. 270: C148-C159.
43. DELPRINCIPE, F., M. EGGER & E. NIGGLI. 1999. Calcium signalling in cardiac muscle: refractoriness revealed by coherent activation. Nat. Cell Biol. 6: 323-329.
44. 2+. exchanger protein levels and diastolic function of failing human myocardium. Circulation 99: 641-648.
45. O'ROURKE, B., D.A. KASS, G.F. TOMASELLI, et al. 1999. Mechanisms of altered excitation-contraction coupling in canine tachycardia-induced heart failure I: experimental studies. Circ. Res. 84: 562-570.
46. 2+ content in isolated failing and nonfailing human myocardium. Circ. Res. 85: 38-46.
47. 2+. exchanger expression and function in an arrhythmogenic rabbit model of heart failure. Circ. Res. 85: 1009-1019.
48. POGWIZD, S.M., K. SCHLOTTHAUER, L. LI, et al. 2001. Arrhythmogenesis and contractile dysfunction in heart failure: roles of sodium-calcium exchange, inward rectifier potassium current, and residual beta-adrenergic responsiveness. Circ. Res. 88: 1095-1096.
49. HOBAI, I.A. & B. O'ROURKE. 2001. Decreased sarcoplasmic reticulum calcium content is responsible for defective excitation-contraction coupling in canine heart failure. Circulation 103: 1577-1584.
50. MARX, S.O., S. REIKEN, Y. HISAMATSU, et al. 2000. PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts. Cell 101: 365-376.
51. 2+. release, but normal ryanodine receptors, in canine and human heart failure. Circ. Res. 91: 1015-1022.
52. LI, Y., E. KRANIAS, G. MIGNERY, et al. 2002. Protein kinase A phosphorylation of the ryanodine receptor does not affect calcium sparks in mouse ventricular myocytes. Circ. Res. 90: 309-316.
53. SHANNON, T.R., S.M. POGWIZD & D.M. BERS. 2003. Elevated sarcoplasmic reticulum Ca leak in intact ventricular myocytes from rabbits in heart failure. Circ. Res. 93: 592-594.
54. SHANNON, T.R. & D.M. BERS. 2001. A mathematical model describes the SR load-dependence of Ca dynamics in cardiac myocytes. Biophys. J. 80: A594.