The δc isoform of CaMKII is activated in cardiac hypertrophy and induces dilated cardiomyopathy and heart failure

Circulation Research

Volumn 92, Issue 8, 2003, Pages 912-919

  Zhang, Tong ^a   Maier, Lars S ^c,d   Dalton, Nancy D ^b   Miyamoto, Shigeki ^a   Ross Jr , John ^b   Bers, Donald M ^c   Brown, Joan Heller ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c LOYOLA UNIVERSITY CHICAGO   (United States)

^d UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

Ca2+ calmodulin dependent protein kinase; Dilated cardiomyopathy; Heart failure; Transgenic mice

Indexed keywords

CALCIUM ION; PHOSPHOLAMBAN; PROTEIN KINASE (CALCIUM,CALMODULIN) II; RYANODINE RECEPTOR; CALCIUM; CALCIUM BINDING PROTEIN; CALMODULIN DEPENDENT PROTEIN KINASE II; CALMODULIN-DEPENDENT PROTEIN KINASE II; ISOENZYME; MESSENGER RNA; PROTEIN KINASE (CALCIUM,CALMODULIN);

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; FEMALE; HEART CELL CULTURE; HEART DILATATION; HEART FAILURE; HEART HYPERTROPHY; HEART MUSCLE CONTRACTILITY; IMMUNOCYTOCHEMISTRY; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE; ANIMAL; C57BL MOUSE; CARDIOMEGALY; CELL CULTURE; CELL SIZE; CONGESTIVE CARDIOMYOPATHY; CONGESTIVE HEART FAILURE; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; HEART MUSCLE; HEART VENTRICLE; MALE; METABOLISM; MORTALITY; NON-PROGRAMMATIC; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGY; STENOSIS, OCCLUSION AND OBSTRUCTION; SURVIVAL RATE; WESTERN BLOTTING;

NON-PROGRAMMATIC;

ANIMALS; BLOTTING, WESTERN; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CALCIUM; CALCIUM-BINDING PROTEINS; CARDIOMEGALY; CARDIOMYOPATHY, DILATED; CELL SIZE; CELLS, CULTURED; CONSTRICTION, PATHOLOGIC; ENZYME ACTIVATION; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HEART FAILURE, CONGESTIVE; HEART VENTRICLES; ISOENZYMES; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MYOCARDIUM; PHOSPHORYLATION; RNA, MESSENGER; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SURVIVAL RATE;

EID: 0038643573     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000069686.31472.C5     Document Type: Article

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