Diminished basal phosphorylation level of phospholamban in the postinfarction remodeled rat ventricle: Role of β-adrenergic pathway, G(i) protein, phosphodiesterase, and phosphatases

Circulation Research

Volumn 85, Issue 9, 1999, Pages 848-855

  Huang, Boyu ^a   Wang, Su ^b   Qin, Dayi ^a   Boutjdir, Mohamed ^a   El Sherif, Nabil ^a  

^a SUNY DOWNSTATE MEDICAL CENTER   (United States)

^b NATIONAL INSTITUTE ON AGING   (United States)

Author keywords

Phosphatase; Phospholamban; Postmyocardial infarction; Sarcoplasmic reticulum

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); ADENYLATE CYCLASE; BETA ADRENERGIC RECEPTOR; CYCLIC AMP DEPENDENT PROTEIN KINASE; GUANINE NUCLEOTIDE BINDING PROTEIN; OKADAIC ACID; PHOSPHATASE; PHOSPHODIESTERASE; PHOSPHOLAMBAN; PHOSPHOPROTEIN PHOSPHATASE; PROTEIN KINASE (CALCIUM,CALMODULIN);

ADRENERGIC SYSTEM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM TRANSPORT; CONTROLLED STUDY; DRESSLER SYNDROME; ENZYME ACTIVITY; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART MUSCLE RELAXATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; RECEPTOR DENSITY; SARCOPLASMIC RETICULUM;

EID: 0032724685     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.85.9.848     Document Type: Article

References (56)

1. Anversa P, Beghi C, Kikkawa Y, Olivetti G. Myocardial infarction in rats. Infarct size, myocyte hypertrophy, and capillary growth. Circ Res. 1986; 58:26-37.
2. Pfeffer JM, Pfeffer MA, Fletcher PJ, Braunwald E. Progressive ventricular remodeling in rat with myocardial infarction. Am J Physiol. 1991; 260:H1406-H1414.
3. Swynghedauw B, ed. Cardiac Hypertrophy and Failure. Paris, France: INSERM/John Libbey; 1990.
4. Gidh-Jain M, Huang B, Jain P, Gick G, El-Sherif N. Alterations in cardiac gene expression during ventricular remodeling following experimental myocardial infarction. J Mol Cell Cardiol. 1998;30:627-637.
5. Morgan JP. Abnormal intracellular modulation of calcium as a major cause of cardiac contractile dysfunction. N Engl J Med. 1991;325: 625-632.
6. Gwathmey JK, Copelas L, MacKinnon R, Schoen FJ, Feldman MD, Grossman W, Morgan JP. Abnormal intracellular calcium handling in myocardium from patients with end-stage heart failure. Circ Res. 1987; 61:70-76.
7. del Monte F, O'Gara P, Poole-Wilson PA, Yacoub M, Harding SE. Cell geometry and contractile abnormalities of myocytes from failing human left ventricle. Cardiovasc Res. 1995;30:281-290.
8. Davies CH, Harding SE, Poole-Wilson PA. Cellular mechanisms of contractile dysfunction in human heart failure. Eur Heart J. 1996;17: 189-198.
9. Hicks MJ, Shigekawa M, Katz AM. Mechanism by which cyclic adenosine 3′:5′-monophosphate-dependent protein kinase stimulates calcium transport in cardiac sarcoplasmic reticulum. Circ Res. 1979;44:384-391.
10. 2+-ATPase with phospholamban in phospholipid vesicle. J Biol Chem. 1990;265:1702-1709.
11. Feldman AM, Ray PE, Silan CM, Mercer JA, Minobe W, Bristow MR. Selective gene expression on failing human heart: quantification of steady-state levels of messenger RNA in endomyocardial biopsies using the polymerase chain reaction. Circulation. 1991;83:1866-1872.
12. 2+-ATPase gene expression in the human ventricle during end-stage heart failure. J Clin Invest. 1990;85:305-309.
13. Arai M, Alpert NR, MacLennan DH, Barton P, Periasamy M. Alterations in sarcoplasmic reticulum gene expression in human heart failure: a possible mechanism for alterations in systolic and diastolic properties of the failing myocardium. Circ Res. 1992;72:463-469.
14. Zarain-Herzberg A, Afzal N, Elimban V, Dhalla NS. Decreased expression of cardiac sarcoplasmic reticulum Ca(2+)-pump ATPase in congestive heart failure due to myocardial infarction. Mol Cell Biochem. 1996;163-164:285-290.
15. Hasenfuss G, Reinecke H, Studer R, Meyer M, Pieske B, Holtz J, Holubarsch C, Posival H, Just H, Drexler H. Relation between myocardial function and expression of sarcoplasmic reticulum Ca2+-ATPase in failing and nonfailing human myocardium. Circ Res. 1994;75:434-442.
16. 2+-transporting ATPase, phospholamban and calsequestrin levels in nonfailing and failing human heart. Circulation. 1994;90:653-657.
17. 2+-ATPase in failing and nonfailing human hearts. Cardiovasc Res. 1996;31:625-632.
18. 2+-ATPase, phospholamban, and calsequestrin in terminally failing human myocardium. J Mol Med. 1998;76:434-441.
19. 2+ uptake and Ca(2+)-ATPase activity of cardiac sarcoplasmic reticulum from dilated cardiomyopathy patients compared with patients with nonfailing hearts. Circulation. 1995;92: 3220-3228.
20. Pfeffer JM, Pfeffer MA, Fletcher PJ, Braunwald E. Ventricular performance in rats with myocardial infarction and failure. Am J Med. 1984; 76:99-103.
21. i transients in hypertensive and postinfarction myocytes. Am J Physiol. 1995;269: C632-C640.
22. Qin D, Zhang ZH, Caref EB, Boutjdir M, Jain P, El-Sherif N. Cellular and ionic basis of arrhythmias in postinfarction remodeled ventricular myocardium. Circ Res. 1996;79:461-473.
23. Stachelin M, Hertel C. [3H]CGP-12177, a beta-adrenergic ligand suitable for measuring cell surface receptors. J Recept Res. 1983;3:35-43.
24. 3H]CGP-12177) binding in adult rat ventricular myocytes: lack of regulation by β-agonists at physiological concentrations. Pflügers Arch. 1992;421:440-446.
25. Munson PJ, Rodbard D. Ligand, a versatile computerized approach for characterization of ligand-binding systems. Anal Biochem. 1980;107: 220-239.
26. Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 1970;227:680-685.
27. Bradford MM. A rapid and sensitive method for quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem. 1976;72:248-254.
28. Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem. 1987;162:156-159.
29. Hwang KS, Nadal-Ginard B. Cloning phospholamban cDNA from rat aortic smooth muscle. Adv Exp Med Biol. 1991;304:387-395.
30. 2+-ATPase mRNA. FEBS Lett. 1989;249:35-41.
31. Danielson P, Forss-Petter S, Brow M, Calavette L, Douglass J, Milner R, Sutcliffe J. p1B15: a cDNA clone of the rat mRNA encoding cyclophilin. DNA. 1988;7:261-267.
32. + channel genes in left ventricular remodeled myocardium after experimental myocardial infarction. Circ Res. 1996;79: 669-675.
33. Neumann J, Gupta RC, Schmitz W, Scholz H, Nairn AC, Watanabe AM. Evidence for isoproterenol-induced phosphorylation of phosphatase inhibitor-1 in the intact heart. Circ Res. 1991;69:1450-1457.
34. Ahmad Z, Green FJ, Subuhi HS, Watanabe AM. Autonomic regulation of type 1 protein phosphatase in cardiac muscle. J Biol Chem. 1989;264: 3859-3863.
35. 2+, contraction, and potential in cardiac myocytes. Am J Physiol. 1990;258: H574-H586.
36. Zimmermann N, Boknik P, Gams E, Gsell S, Jones LR, Maas R, Neumann J, Scholz H. Mechanisms of the contractile effects of 2,3-butanedione-monoxime in the mammalian heart. Naunyn Schmiedebergs Arch Pharmacol. 1996;354:431-436.
37. Wera S, Hemmings BA. Serine/threonine protein phosphatases. Biochem J. 1995;311(Pt 1):17-29.
38. MacDougall LK, Jones LR, Cohen P. Identification of the major protein phosphatases in mammalian cardiac muscle which dephosphorylate phospholamban. Eur J Biochem. 1991;196:725-734.
39. Neumann J, Eschenhagen T, Jones LR, Linck B, Schmitz W, Scholz H, Zimmermann N. Increased expression of cardiac phosphatases in patients with end-stage heart failure. J Mol Cell Cardiol. 1997;29:265-272.
40. Luo W, Chu G, Sato Y, Zhou Z, Kadambi VJ, Kranias EG. Transgenic approaches to define the functional role of dual site phospholamban phosphorylation. J Biol Chem. 1998;273:4734-4739.
41. s or phosphorylating proteins. J Mol Cell Cardiol. 1999;31:1185-1201.
42. i during pacing-induced heart failure. Circulation. 1996;94:102-107.
43. Feldman AM, Cates AE, Veazey WB, Hershberger RE, Bristow MR, Baughman KL, Baumgartner WA, Van Dop C. Increase of the 40,000-mol wt pertussis toxin substrate (G protein) in the failing human heart. J Clin Invest. 1988;82:189-197.
44. Gupta RC, Neumann J, Watanabe AM, Sabbah HN. Muscarinic-cholinoceptor mediated attenuation of phospholamban phosphorylation induced by inhibition of phosphodiesterase in ventricular cardiomyocytes: evidence against a cAMP-dependent effect. Mol Cell Biochem. 1998;187:155-161.
45. Gupta RC, Neumann J, Watanabe AM. Comparison of adenosine and muscarinic receptor-mediated effects on protein phosphatase inhibitor-1 activity in the heart. J Pharmacol Exp Ther. 1993;266:16-22.
46. Steenart NAE, Ganim JR, Di Salvo JD, Kranias EG. The phospholamban phosphatase associated with cardiac sarcoplasmic reticulum is a type 1 enzyme. Arch Biochem Biophys. 1991;297:17-24.
47. Sulakhe PV, Vo XT, Morris TE, Pato MD, Khandelwal RL. Protein phosphorylation in rat cardiac microsomes: effects of inhibitors of protein kinase A and of phosphatases. Mol Cell Biochem. 1997;175:109-115.
48. Yamamoto J, Ohyanagi M, Morita M. Iwasaki T. Beta-adrenoceptor-G protein-adenylate cyclase complex in rat hearts with ischemic heart failure produced by coronary artery ligation. J Mol Cell Cardiol. 1994; 26:617-626.
49. Luo W, Grupp IL, Harrer J, Ponniah S, Grupp G, Duffy JJ, Doetschman T, Kranias EG. Targeted ablation of the phospholamban gene is associated with markedly enhanced myocardial contractility and loss of β-agonist stimulation. Circ Res. 1994;75:401-409.
50. Kranias EG, Solaro RJ. Phosphorylation of troponin I and phospholamban during catecholamine stimulation of rabbit heart. Nature. 1982; 298:182-184.
51. 2+-ATPase activity in guinea pig ventricles. J Biol Chem. 1983;258: 464-471.
52. Wegner AD, Simmerman HKB, Lindemann JP, Jones LR. Phospholamban phosphorylation in intact ventricles. J Biol Chem. 1989;264: 11468-11474.
53. Koss KL, Kranias EG. Phospholamban: a prominent regulator of myocardial contractility. Circ Res. 1996;79:1059-1063.
54. Mundina de Weilenmann C, Vittone L, deCingolani G, Mattiazi A. Dissociation between contraction and relaxation: the possible role of phospholamban phosphorylation. Basic Res Cardiol. 1987;82:507-516.
55. Garvey JL, Kranias EG, Solaro RJ. Phosphorylation of C-protein, troponin I and phospholamban in isolated rabbit hearts. Biochem J. 1988;249:709-714.
56. Gupta RC, Neumann J, Watanabe AM, Lesch M, Sabbah HN. Evidence for presence and hormonal regulation of protein phosphatase inhibitor-1 in ventricular cardiomyocyte. Am J Physiol. 1996;270(4 pt 2):H1159-H1164.