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Volumn 29, Issue 5, 1997, Pages 365-385

Autophagic proteolysis: Control and specificity

Author keywords

[No Author keywords available]

Indexed keywords

AUTOPHAGY; CELL ENERGY; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN PHOSPHORYLATION; REVIEW; SIGNAL TRANSDUCTION;

EID: 0030957959     PISSN: 00182214     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1026486801018     Document Type: Review
Times cited : (217)

References (200)
  • 1
    • 0020402944 scopus 로고
    • Uptake and degradation of proteins by isolated rat liver lysosomes. Suggestion of a microautophagic pathway of proteolysis
    • AHLBERG, J., MARZELLA, L. & GLAUMANN, H. (1982) Uptake and degradation of proteins by isolated rat liver lysosomes. Suggestion of a microautophagic pathway of proteolysis. Lab. Invest. 47, 523-32.
    • (1982) Lab. Invest. , vol.47 , pp. 523-532
    • Ahlberg, J.1    Marzella, L.2    Glaumann, H.3
  • 2
    • 0026787605 scopus 로고
    • Cytoskeletal elements are required for the formation and maturation of autophagic vacuoles
    • APLIN, A., JASIANOWSKI, T., TUTTLE, D. L., LENK, S. E. & DUNN, W. A. (1992) Cytoskeletal elements are required for the formation and maturation of autophagic vacuoles. J. Cell. Physiol. 152, 458-66.
    • (1992) J. Cell. Physiol. , vol.152 , pp. 458-466
    • Aplin, A.1    Jasianowski, T.2    Tuttle, D.L.3    Lenk, S.E.4    Dunn, W.A.5
  • 4
    • 0024601010 scopus 로고
    • PDGF-dependent tyrosine phosphorylation stimulates production of novel polyphosphoinositides in intact cells
    • AUGER, K. R., SERUNIAN, L. A., SOLTOFF, S. P., LIBBY, P. & CANTLEY, L. C. (1989) PDGF-dependent tyrosine phosphorylation stimulates production of novel polyphosphoinositides in intact cells. Cell 57, 167-75.
    • (1989) Cell , vol.57 , pp. 167-175
    • Auger, K.R.1    Serunian, L.A.2    Soltoff, S.P.3    Libby, P.4    Cantley, L.C.5
  • 5
    • 0028230738 scopus 로고
    • Ultrastructural analysis of the autophagic process in yeast. Detection of autophagosomes and their characterization
    • BABA, M., TAKESHIGE, K., BABA, N. & OHSUMI, Y. (1994) Ultrastructural analysis of the autophagic process in yeast. Detection of autophagosomes and their characterization. J. Cell Biol. 124, 903-13.
    • (1994) J. Cell Biol. , vol.124 , pp. 903-913
    • Baba, M.1    Takeshige, K.2    Baba, N.3    Ohsumi, Y.4
  • 6
    • 0030009316 scopus 로고    scopus 로고
    • The acidosis of chronic renal failure activates muscle proteolysis in rats by augmenting transcription of genes encoding proteins of the ATP-dependent ubiquitin-proteasome pathway
    • BAILEY, J. L., WANG, X., ENGLAND, B. K., PRICE, S. R., DING, X. & MITCH, W. E. (1996) The acidosis of chronic renal failure activates muscle proteolysis in rats by augmenting transcription of genes encoding proteins of the ATP-dependent ubiquitin-proteasome pathway. J. Clin. Invest. 97, 1447-53.
    • (1996) J. Clin. Invest. , vol.97 , pp. 1447-1453
    • Bailey, J.L.1    Wang, X.2    England, B.K.3    Price, S.R.4    Ding, X.5    Mitch, W.E.6
  • 8
    • 0025863586 scopus 로고
    • Swelling of rat hepatocytes activates acetylCoA carboxylase in parallel to glycogen synthase
    • BAQUET, A., MAISIN, L. & HUE, L. (1991a) Swelling of rat hepatocytes activates acetylCoA carboxylase in parallel to glycogen synthase. Biochem. J. 278, 887-90.
    • (1991) Biochem. J. , vol.278 , pp. 887-890
    • Baquet, A.1    Maisin, L.2    Hue, L.3
  • 11
    • 0029077946 scopus 로고
    • Disruption of the cytokeratin cytoskeleton and inhibition of hepatic autophagy by okadaic acid
    • BLANKSON, H., HOLEN, I. & SEGLEN, P. O. (1995) Disruption of the cytokeratin cytoskeleton and inhibition of hepatic autophagy by okadaic acid. Exp. Cell Res. 218, 522-30.
    • (1995) Exp. Cell Res. , vol.218 , pp. 522-530
    • Blankson, H.1    Holen, I.2    Seglen, P.O.3
  • 12
    • 8244244231 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase activity is essential for autophagy - A mechanism for 3-methyladenine action
    • Abstract 101. Turku, Finland
    • BLOMMAART, E. F. C. & MEIJER, A. J. (1996) Phosphatidylinositol 3-kinase activity is essential for autophagy - a mechanism for 3-methyladenine action. 11th International Conference on Proteolysis and Protein Turnover. Abstract 101. Turku, Finland.
    • (1996) 11th International Conference on Proteolysis and Protein Turnover
    • Blommaart, E.F.C.1    Meijer, A.J.2
  • 13
    • 0027470686 scopus 로고
    • Effects of intracellular amino acid concentrations, cyclic AMP, and dexamethasone on lysosomal proteolysis in primary cultures of perinatal rat hepatocytes
    • BLOMMAART, P. J. E., ZONNEVELD, D., MEIJER, A. J. & LAMERS, W. H. (1993) Effects of intracellular amino acid concentrations, cyclic AMP, and dexamethasone on lysosomal proteolysis in primary cultures of perinatal rat hepatocytes. J. Biol. Chem. 268, 1610-17.
    • (1993) J. Biol. Chem. , vol.268 , pp. 1610-1617
    • Blommaart, P.J.E.1    Zonneveld, D.2    Meijer, A.J.3    Lamers, W.H.4
  • 14
    • 0028899789 scopus 로고
    • Phosphorylation of ribosomal protein S6 is inhibitory for autophagy in isolated rat hepatocytes
    • BLOMMAART, E. F. C., LUIKEN, J. J. F. P., BLOMMAART, P. J. E., VAN WOERKOM, G. M. & MEIJER, A. J. (1995) Phosphorylation of ribosomal protein S6 is inhibitory for autophagy in isolated rat hepatocytes. J. Biol. Chem. 270, 2320-6.
    • (1995) J. Biol. Chem. , vol.270 , pp. 2320-2326
    • Blommaart, E.F.C.1    Luiken, J.J.F.P.2    Blommaart, P.J.E.3    Van Woerkom, G.M.4    Meijer, A.J.5
  • 15
    • 8044257699 scopus 로고    scopus 로고
    • The phosphatidylinositol 3-kinase inhibitors wortmannin and LY294002 inhibit autophagy in isolated rat hepatocytes
    • BLOMMAART, E. F. C., KRAUSE, U., SCHELLENS, J. P. M., VREELING-SINDELÀROVA, H. & MEIJER, A. J. (1997) The phosphatidylinositol 3-kinase inhibitors wortmannin and LY294002 inhibit autophagy in isolated rat hepatocytes. Eur. J. Biochem. 243, 240-6.
    • (1997) Eur. J. Biochem. , vol.243 , pp. 240-246
    • Blommaart, E.F.C.1    Krause, U.2    Schellens, J.P.M.3    Vreeling-Sindelàrova, H.4    Meijer, A.J.5
  • 16
    • 0028838845 scopus 로고
    • A target for phosphoinositide 3-kinase: Akt/PKB
    • BOS, J. L. (1995) A target for phosphoinositide 3-kinase: Akt/PKB. Trends Biochem. Sci. 20, 441-2.
    • (1995) Trends Biochem. Sci. , vol.20 , pp. 441-442
    • Bos, J.L.1
  • 17
    • 0029148577 scopus 로고
    • Role for phosphatidylinositol 3-kinase in the sorting and transport of newly synthesized lysosomal enzymes in mammalian cells
    • BROWN, W. J., DE WALD, D. B., EMR, S. D., PLUNTER, H. & BALCH, W. E. (1995) Role for phosphatidylinositol 3-kinase in the sorting and transport of newly synthesized lysosomal enzymes in mammalian cells. J. Cell Biol. 130, 781-96.
    • (1995) J. Cell Biol. , vol.130 , pp. 781-796
    • Brown, W.J.1    De Wald, D.B.2    Emr, S.D.3    Plunter, H.4    Balch, W.E.5
  • 18
    • 0028566190 scopus 로고
    • Involvement of microtubules in the link between cell volume and pH of acidic cellular compartments in rat and human hepatocytes
    • BUSCH, G. L., SCHREIBER, R., DARTSCH, P. C., VÖLKL, H., DAHL, S. V., HÄUSSINGER, D. & LANG, F. (1994) Involvement of microtubules in the link between cell volume and pH of acidic cellular compartments in rat and human hepatocytes. Proc. Natl. Acad. Sci. USA 91, 9165-9.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 9165-9169
    • Busch, G.L.1    Schreiber, R.2    Dartsch, P.C.3    Völkl, H.4    Dahl, S.V.5    Häussinger, D.6    Lang, F.7
  • 20
    • 0028867855 scopus 로고
    • Wortmannin inhibits transcytosis of dimeric IgA by the polymeric immunoglobulin receptor
    • CARDONE, M. & MOSTOV, K. (1995) Wortmannin inhibits transcytosis of dimeric IgA by the polymeric immunoglobulin receptor. FEBS Lett. 376, 74-6.
    • (1995) FEBS Lett. , vol.376 , pp. 74-76
    • Cardone, M.1    Mostov, K.2
  • 22
    • 0024402231 scopus 로고
    • A combination of intracellular leucine with either glutamate or aspartate inhibits autophagic proteolysis in isolated rat hepatocytes
    • CARO, L. H. P., PLOMP, P. J. A. M., LEVERVE, X. M. & MEIJER, A. J. (1989) A combination of intracellular leucine with either glutamate or aspartate inhibits autophagic proteolysis in isolated rat hepatocytes. Eur. J. Biochem. 181, 717-20.
    • (1989) Eur. J. Biochem. , vol.181 , pp. 717-720
    • Caro, L.H.P.1    Plomp, P.J.A.M.2    Leverve, X.M.3    Meijer, A.J.4
  • 23
    • 0028308412 scopus 로고
    • Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation
    • CHEATHAM, B., VLAHOS, C. J., CHEATHAM, L., WANG, L., BLENIS, J. & KAHN, C. R. (1994) Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation. Mol. Cell. Biol. 14, 4902-11.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 4902-4911
    • Cheatham, B.1    Vlahos, C.J.2    Cheatham, L.3    Wang, L.4    Blenis, J.5    Kahn, C.R.6
  • 24
    • 0025804582 scopus 로고
    • Regulated import and degradation of a cytosolic protein in the yeast vacuole
    • CHIANG, H. L. & SCHEKMAN, R. (1991) Regulated import and degradation of a cytosolic protein in the yeast vacuole. Nature 350, 313-18.
    • (1991) Nature , vol.350 , pp. 313-318
    • Chiang, H.L.1    Schekman, R.2
  • 25
    • 0029875385 scopus 로고    scopus 로고
    • Selective uptake of cytosolic, peroxisomal, and plasma membrane proteins into the yeast lysosome for degradation
    • CHIANG, H. L., SCHEKMAN, R. & HAMAMOTO, S. (1996) Selective uptake of cytosolic, peroxisomal, and plasma membrane proteins into the yeast lysosome for degradation. J. Biol. Chem. 271, 9934-41.
    • (1996) J. Biol. Chem. , vol.271 , pp. 9934-9941
    • Chiang, H.L.1    Schekman, R.2    Hamamoto, S.3
  • 26
    • 0028788935 scopus 로고
    • The 70 kDa S6 kinase: Regulation of a kinase with multiple roles in mitogenic signalling
    • CHOU, M. M. & BLENIS, J. (1995) The 70 kDa S6 kinase: regulation of a kinase with multiple roles in mitogenic signalling. Curr. Biol. 7, 806-14.
    • (1995) Curr. Biol. , vol.7 , pp. 806-814
    • Chou, M.M.1    Blenis, J.2
  • 27
    • 0028223809 scopus 로고
    • Specificity of leucine effect on protein degradation in perfused rat heart
    • CHUA, B. H. L. (1994) Specificity of leucine effect on protein degradation in perfused rat heart. J. Mol. Cell. Cardiol. 26, 743-51.
    • (1994) J. Mol. Cell. Cardiol. , vol.26 , pp. 743-751
    • Chua, B.H.L.1
  • 28
    • 0028178928 scopus 로고
    • PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase
    • CHUNG, J., GRAMMER, T. C., LEMON, K. P., KAZLAUSKAS, A. & BLENIS, J. (1994) PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase. Nature 370, 71-5.
    • (1994) Nature , vol.370 , pp. 71-75
    • Chung, J.1    Grammer, T.C.2    Lemon, K.P.3    Kazlauskas, A.4    Blenis, J.5
  • 29
    • 0028979563 scopus 로고
    • Phosphatidylinositol 3-kinase regulation of fluid phase endocytosis
    • CLAGUE, M. J., THORPE, C. & JONES, A. T. (1995) Phosphatidylinositol 3-kinase regulation of fluid phase endocytosis. FEBS Lett. 367, 272-4.
    • (1995) FEBS Lett. , vol.367 , pp. 272-274
    • Clague, M.J.1    Thorpe, C.2    Jones, A.T.3
  • 30
    • 0028260280 scopus 로고
    • Inhibition of the translocation of GLUT1 and GLUT4 in 3T3-L1 cells by the phosphatidylinositol 3-kinase inhibitor, wortmannin
    • CLARKE, J. F., YOUNG, P. W., YONEZAWA, K., KASUGA, M. & HOLMAN, G. D. (1994) Inhibition of the translocation of GLUT1 and GLUT4 in 3T3-L1 cells by the phosphatidylinositol 3-kinase inhibitor, wortmannin. Biochem. J. 300, 631-5.
    • (1994) Biochem. J. , vol.300 , pp. 631-635
    • Clarke, J.F.1    Young, P.W.2    Yonezawa, K.3    Kasuga, M.4    Holman, G.D.5
  • 31
    • 0021321990 scopus 로고
    • Lysosomes are associated with microtubules and not with intermediate filaments in fibroblasts
    • COLLOT, M., LOUVARD, D. & SINGER, S. J. (1984) Lysosomes are associated with microtubules and not with intermediate filaments in fibroblasts. Proc. Natl. Acad. Sci. USA 81, 788-92.
    • (1984) Proc. Natl. Acad. Sci. USA , vol.81 , pp. 788-792
    • Collot, M.1    Louvard, D.2    Singer, S.J.3
  • 32
    • 0029837453 scopus 로고    scopus 로고
    • A receptor for the selective uptake and degradation of proteins by lysosomes
    • CUERVO, A. M. & DICE, J. F. (1996) A receptor for the selective uptake and degradation of proteins by lysosomes. Science 273, 501-3.
    • (1996) Science , vol.273 , pp. 501-503
    • Cuervo, A.M.1    Dice, J.F.2
  • 33
    • 0028848119 scopus 로고
    • Activation of a selective pathway of lysosomal proteolysis in rat liver by prolonged starvation
    • CUERVO, A. M., KNECHT, E., TERLECKI, S. R. & DICE, J. F. (1995) Activation of a selective pathway of lysosomal proteolysis in rat liver by prolonged starvation. Am. J. Physiol. 269, C1200-8.
    • (1995) Am. J. Physiol. , vol.269
    • Cuervo, A.M.1    Knecht, E.2    Terlecki, S.R.3    Dice, J.F.4
  • 34
  • 35
    • 0029123267 scopus 로고
    • Wortmannin causes mistargeting of procathepsin D. The involvement of a phosphatidylinositol 3-kinase in vesicular transport to lysosomes
    • DAVIDSON, H. W. (1995) Wortmannin causes mistargeting of procathepsin D. The involvement of a phosphatidylinositol 3-kinase in vesicular transport to lysosomes. J. Cell. Biol. 130, 797-805.
    • (1995) J. Cell. Biol. , vol.130 , pp. 797-805
    • Davidson, H.W.1
  • 36
    • 0022568933 scopus 로고
    • Quantitative changes in the lysosomal vacuolar system of rat hepatocytes during short-term starvation. A morphometric analysis with special reference to macro- and micro-autophagy
    • DE WAAL, E. J., VREELING-SINDELÁROVÁ, H., SCHELLENS, J. P. M., HOUTKOPER, J. M. & JAMES, J. (1986) Quantitative changes in the lysosomal vacuolar system of rat hepatocytes during short-term starvation. A morphometric analysis with special reference to macro- and micro-autophagy. Cell Tissue Res. 234, 641-8.
    • (1986) Cell Tissue Res. , vol.234 , pp. 641-648
    • De Waal, E.J.1    Vreeling-Sindelárová, H.2    Schellens, J.P.M.3    Houtkoper, J.M.4    James, J.5
  • 37
    • 0025294506 scopus 로고
    • Peptide sequences that target cytosolic proteins for lysosomal proteolysis
    • DICE, J. F. (1990) Peptide sequences that target cytosolic proteins for lysosomal proteolysis. Trends Biochem. Sci. 15, 305-9.
    • (1990) Trends Biochem. Sci. , vol.15 , pp. 305-309
    • Dice, J.F.1
  • 38
    • 0028328655 scopus 로고
    • Rapamycin selectively inhibits the growth of childhood rhabdomyosarcoma cells through inhibition of signaling via the type I insulin-like growth factor receptor
    • DILLING, M. B., DIAS, P., SHAPIRO, D. N., GERMAIN, G. S., JOHNSON, R. K. & HOUGHTON, P. J. (1994) Rapamycin selectively inhibits the growth of childhood rhabdomyosarcoma cells through inhibition of signaling via the type I insulin-like growth factor receptor. Cancer Res. 54, 903-7.
    • (1994) Cancer Res. , vol.54 , pp. 903-907
    • Dilling, M.B.1    Dias, P.2    Shapiro, D.N.3    Germain, G.S.4    Johnson, R.K.5    Houghton, P.J.6
  • 39
    • 0024463635 scopus 로고
    • Ubiquitin-protein conjugates accumulate in the lysosomal system of fibroblasts treated with cysteine proteinase inhibitors
    • DOHERTY, F. J., OSBORNE, N. U., WASSELL, J. A., HEGGIE, P. E., LASZLO, L. & MAYER, R. J. (1989) Ubiquitin-protein conjugates accumulate in the lysosomal system of fibroblasts treated with cysteine proteinase inhibitors. Biochem. J. 263, 47-55.
    • (1989) Biochem. J. , vol.263 , pp. 47-55
    • Doherty, F.J.1    Osborne, N.U.2    Wassell, J.A.3    Heggie, P.E.4    Laszlo, L.5    Mayer, R.J.6
  • 40
    • 0025363276 scopus 로고
    • Studies on the mechanisms of autophagy: Formation of the autophagic vacuole
    • DUNN, W. A. (1990a) Studies on the mechanisms of autophagy: formation of the autophagic vacuole. J. Cell Biol. 110, 1923-33.
    • (1990) J. Cell Biol. , vol.110 , pp. 1923-1933
    • Dunn, W.A.1
  • 41
    • 0025340880 scopus 로고
    • Studies on the mechanisms of autophagy: Maturation of the autophagic vacuole
    • DUNN, W. A. (1990b) Studies on the mechanisms of autophagy: maturation of the autophagic vacuole. J. Cell Biol. 110, 1935-45.
    • (1990) J. Cell Biol. , vol.110 , pp. 1935-1945
    • Dunn, W.A.1
  • 42
    • 0028222874 scopus 로고
    • Autophagy and related mechanisms of lysosome-mediated protein degradation
    • DUNN, W. A. (1994) Autophagy and related mechanisms of lysosome-mediated protein degradation. Trends Cell Biol. 4, 139-43.
    • (1994) Trends Cell Biol. , vol.4 , pp. 139-143
    • Dunn, W.A.1
  • 43
    • 0029024435 scopus 로고
    • The effects of wortmannin, a potent inhibitor of phosphatidylinositol 3-kinase, on insulin stimulated glucose transport, GLUT4 translocation, antilipolysis, and DNA synthesis
    • EVANS, J. L., HONER, C. M., WOMELSDORF, B. E., KAPLAN, E. L. & BELL, P. A. (1995) The effects of wortmannin, a potent inhibitor of phosphatidylinositol 3-kinase, on insulin stimulated glucose transport, GLUT4 translocation, antilipolysis, and DNA synthesis. Cell Signalling 7, 365-76.
    • (1995) Cell Signalling , vol.7 , pp. 365-376
    • Evans, J.L.1    Honer, C.M.2    Womelsdorf, B.E.3    Kaplan, E.L.4    Bell, P.A.5
  • 44
    • 0026544023 scopus 로고
    • Cytoskeletal changes in hepatocytes induced by microcystis toxins and their relation to hyperphosphorylation of cell proteins
    • FALCONER, I. R. & YEUNG, D. S. (1992) Cytoskeletal changes in hepatocytes induced by microcystis toxins and their relation to hyperphosphorylation of cell proteins. Chem. Biol. Interactions 81, 181-96.
    • (1992) Chem. Biol. Interactions , vol.81 , pp. 181-196
    • Falconer, I.R.1    Yeung, D.S.2
  • 45
    • 0028856914 scopus 로고
    • Ultrastructural and immunocytochemical characterization of autophagic vacuoles in isolated hepatocytes: Effects of vinblastine and asparagine on vacuole distributions
    • FENGSRUD, M., ROOS, N., BERG, T., LIOU, W. L., SLOT, J. W. & SEGLEN, P. O. (1995) Ultrastructural and immunocytochemical characterization of autophagic vacuoles in isolated hepatocytes: effects of vinblastine and asparagine on vacuole distributions. Exp. Cell Res. 221, 504-19.
    • (1995) Exp. Cell Res. , vol.221 , pp. 504-519
    • Fengsrud, M.1    Roos, N.2    Berg, T.3    Liou, W.L.4    Slot, J.W.5    Seglen, P.O.6
  • 46
    • 0029915988 scopus 로고    scopus 로고
    • Progressive cellular dehydration and proteolysis in critically ill patients
    • FINN, P. J., PLANK, L. D., CLARK, M. A., CONNOLLY, A. B. & HILL, G. L. (1996) Progressive cellular dehydration and proteolysis in critically ill patients. Lancet 347, 654-6.
    • (1996) Lancet , vol.347 , pp. 654-656
    • Finn, P.J.1    Plank, L.D.2    Clark, M.A.3    Connolly, A.B.4    Hill, G.L.5
  • 47
    • 0029044483 scopus 로고
    • Vanadate inhibition of hepatocytic autophagy - Calcium-modulated and osmolality-modulated antagonism by asparagine
    • FOSSE, H., BERG, T. O., OREILLY, D. S. J. & SEGLEN, P. O. (1995) Vanadate inhibition of hepatocytic autophagy - calcium-modulated and osmolality-modulated antagonism by asparagine. Eur. J. Biochem. 230, 17-24.
    • (1995) Eur. J. Biochem. , vol.230 , pp. 17-24
    • Fosse, H.1    Berg, T.O.2    Oreilly, D.S.J.3    Seglen, P.O.4
  • 48
    • 0029867412 scopus 로고    scopus 로고
    • The metabolism of sphingo(glyco)lipids is correlated with the differentiation-dependent autophagic pathway in HT-29 cells
    • GHIDONI, R., HOURI, J. J. , GIULIANI, A., OGIER-DENIS, E., PAROLARI E., BOTTI, S., BAUVY, C. & CODOGNO, P. (1996) The metabolism of sphingo(glyco)lipids is correlated with the differentiation-dependent autophagic pathway in HT-29 cells. Eur. J. Biochem. 237, 454-9.
    • (1996) Eur. J. Biochem. , vol.237 , pp. 454-459
    • Ghidoni, R.1    Houri, J.J.2    Giuliani, A.3    Ogier-Denis, E.4    Parolari, E.5    Botti, S.6    Bauvy, C.7    Codogno, P.8
  • 49
    • 0024299286 scopus 로고
    • Prelysosomal convergence of autophagic and endocytic pathways
    • GORDON, P. B. & SEGLEN, P. O. (1988) Prelysosomal convergence of autophagic and endocytic pathways. Biochem. Biophys. Res. Commun. 151, 40-7.
    • (1988) Biochem. Biophys. Res. Commun. , vol.151 , pp. 40-47
    • Gordon, P.B.1    Seglen, P.O.2
  • 50
    • 0026559695 scopus 로고
    • Prelysosomal and lysosomal connections between autophagy and endocytosis
    • GORDON, P. B., HOYVIK, H. & SEGLEN, P. O. (1992) Prelysosomal and lysosomal connections between autophagy and endocytosis. Biochem. J. 283, 361-9.
    • (1992) Biochem. J. , vol.283 , pp. 361-369
    • Gordon, P.B.1    Hoyvik, H.2    Seglen, P.O.3
  • 51
    • 0027495705 scopus 로고
    • Dependence of hepatocytic autophagy on intracellularly sequestered calcium
    • GORDON, P. B., HOLEN, I., FOSSE, M., ROTNES, J. S. & SEGLEN, P. O. (1993) Dependence of hepatocytic autophagy on intracellularly sequestered calcium. J. Biol. Chem. 268, 26107-12.
    • (1993) J. Biol. Chem. , vol.268 , pp. 26107-26112
    • Gordon, P.B.1    Holen, I.2    Fosse, M.3    Rotnes, J.S.4    Seglen, P.O.5
  • 52
    • 0028957045 scopus 로고
    • Protection by naringin and some other flavonoids of hepatocytic autophagy and endocytosis against inhibition by okadaic acid
    • GORDON, P. B., HOLEN, I. & SEGLEN, P. O. (1995) Protection by naringin and some other flavonoids of hepatocytic autophagy and endocytosis against inhibition by okadaic acid. J. Biol. Chem. 270, 5830-8.
    • (1995) J. Biol. Chem. , vol.270 , pp. 5830-5838
    • Gordon, P.B.1    Holen, I.2    Seglen, P.O.3
  • 53
    • 0025818893 scopus 로고
    • The ubiquitin-activating enzyme, E1, is required for stress-induced lysosomal degradation of cellular proteins
    • GROPPER, R., BRANDT, R. A., ELIAS, S., BEARER, C. F., MAYER, A., SCHWARTZ, A. L. & CIECHANOVER, A. (1991) The ubiquitin-activating enzyme, E1, is required for stress-induced lysosomal degradation of cellular proteins. J. Biol. Chem. 266, 3602-10.
    • (1991) J. Biol. Chem. , vol.266 , pp. 3602-3610
    • Gropper, R.1    Brandt, R.A.2    Elias, S.3    Bearer, C.F.4    Mayer, A.5    Schwartz, A.L.6    Ciechanover, A.7
  • 54
    • 0030045693 scopus 로고
    • The TOR signalling pathway and growth control in yeast
    • HALL, M. N. (1995) The TOR signalling pathway and growth control in yeast. Biochem. Soc. Trans. 24, 234-9.
    • (1995) Biochem. Soc. Trans. , vol.24 , pp. 234-239
    • Hall, M.N.1
  • 55
    • 0025905285 scopus 로고
    • Control of hepatic proteolysis by amino acids. The role of cell volume
    • HALLBRUCKER, C., VOM DAHL, S., LANG, F. & HÄUSSINGER, D. (1991a) Control of hepatic proteolysis by amino acids. The role of cell volume. Eur. J. Biochem. 197, 717-24.
    • (1991) Eur. J. Biochem. , vol.197 , pp. 717-724
    • Hallbrucker, C.1    Vom Dahl, S.2    Lang, F.3    Häussinger, D.4
  • 57
    • 0030048284 scopus 로고    scopus 로고
    • The role of cellular hydration in the regulation of cell function
    • HÄUSSINGER, D. (1996) The role of cellular hydration in the regulation of cell function. Biochem. J. 313, 697-710.
    • (1996) Biochem. J. , vol.313 , pp. 697-710
    • Häussinger, D.1
  • 58
    • 0025719586 scopus 로고
    • Cell volume in the regulation of hepatic function: A mechanism for metabolic control
    • HÄUSSINGER, D. & LANG, F. (1991) Cell volume in the regulation of hepatic function: a mechanism for metabolic control. Biochim. Biophys. Acta 1071, 331-50.
    • (1991) Biochim. Biophys. Acta , vol.1071 , pp. 331-350
    • Häussinger, D.1    Lang, F.2
  • 60
    • 0027310314 scopus 로고
    • Cellular hydration state, an important determinant of protein catabolism in health and disease
    • HÄUSSINGER, D., ROTH, E., LANG, F. & GEROK, W. (1993) Cellular hydration state, an important determinant of protein catabolism in health and disease. Lancet 341, 1330-2.
    • (1993) Lancet , vol.341 , pp. 1330-1332
    • Häussinger, D.1    Roth, E.2    Lang, F.3    Gerok, W.4
  • 62
    • 0026663539 scopus 로고
    • The ubiquitin system for protein degradation
    • HERSHKO, A. & CIECHANOVER, A. (1992) The ubiquitin system for protein degradation. Ann. Rev. Biochem. 61, 761-807.
    • (1992) Ann. Rev. Biochem. , vol.61 , pp. 761-807
    • Hershko, A.1    Ciechanover, A.2
  • 63
    • 0029867623 scopus 로고    scopus 로고
    • Proteasomes: Destruction as a programme
    • HILT, W. & WOLF, D. H. (1996) Proteasomes: destruction as a programme. Trends Biochem. Sci. 21, 96-102.
    • (1996) Trends Biochem. Sci. , vol.21 , pp. 96-102
    • Hilt, W.1    Wolf, D.H.2
  • 64
    • 0024594966 scopus 로고
    • Membrane mechanisms in volume and pH regulation in vertebrate cells
    • HOFFMANN, E. K. & SIMONSEN, L. O. (1989) Membrane mechanisms in volume and pH regulation in vertebrate cells. Physiol. Rev. 69, 315-82.
    • (1989) Physiol. Rev. , vol.69 , pp. 315-382
    • Hoffmann, E.K.1    Simonsen, L.O.2
  • 65
    • 0026645413 scopus 로고
    • Protein kinase-dependent effects of okadaic acid on hepatocytic autophagy and cytoskeletal integrity
    • HOLEN, I., GORDON, P. B. & SEGLEN, P. O. (1992) Protein kinase-dependent effects of okadaic acid on hepatocytic autophagy and cytoskeletal integrity. Biochem. J. 284, 633-6.
    • (1992) Biochem. J. , vol.284 , pp. 633-636
    • Holen, I.1    Gordon, P.B.2    Seglen, P.O.3
  • 66
    • 0027296748 scopus 로고
    • Inhibition of hepatic autophagy by okadaic acid and other protein phosphatase inhibitors
    • HOLEN, I., GORDON, P. B. & SEGLEN, P. O. (1993) Inhibition of hepatic autophagy by okadaic acid and other protein phosphatase inhibitors. Eur. J. Biochem. 215, 113-22.
    • (1993) Eur. J. Biochem. , vol.215 , pp. 113-122
    • Holen, I.1    Gordon, P.B.2    Seglen, P.O.3
  • 67
    • 0029046985 scopus 로고
    • Inhibition of autophagy and multiple steps in asialoglycoprotein endocytosis by inhibitors of tyrosine protein kinases (tyrphostins)
    • HOLEN, I., STRØMHAUG, P. E., GORDON, P. B., FENGSRUD, M., BERG, T. O. & SEGLEN, P. O. (1995) Inhibition of autophagy and multiple steps in asialoglycoprotein endocytosis by inhibitors of tyrosine protein kinases (tyrphostins). J. Biol. Chem. 270, 12823-31.
    • (1995) J. Biol. Chem. , vol.270 , pp. 12823-12831
    • Holen, I.1    Strømhaug, P.E.2    Gordon, P.B.3    Fengsrud, M.4    Berg, T.O.5    Seglen, P.O.6
  • 68
    • 0027772643 scopus 로고
    • Autophagic degradation of N-linked glycoproteins is downregulated in differentiated human colon adenocarcinoma cells
    • HOURI, J. J., OGIER-DENIS, E., TRUGNAN, G. & CODOGNO, P. (1993) Autophagic degradation of N-linked glycoproteins is downregulated in differentiated human colon adenocarcinoma cells. Biochem. Biophys. Res. Commun. 197, 805-11.
    • (1993) Biochem. Biophys. Res. Commun. , vol.197 , pp. 805-811
    • Houri, J.J.1    Ogier-Denis, E.2    Trugnan, G.3    Codogno, P.4
  • 69
    • 0029036657 scopus 로고
    • Differentiation-dependent autophagy controls the fate of newly synthesized N-linked glycoproteins in the colon adenocarcinoma HT-29 cell line
    • HOURI, J. J., OGIER-DENIS, E., DE STEFANIS, D., BAUVY, C., BACCINO, F., ISIDORO, C. & CODOGNO, P. (1995) Differentiation-dependent autophagy controls the fate of newly synthesized N-linked glycoproteins in the colon adenocarcinoma HT-29 cell line. Biochem. J. 309, 521-7.
    • (1995) Biochem. J. , vol.309 , pp. 521-527
    • Houri, J.J.1    Ogier-Denis, E.2    De Stefanis, D.3    Bauvy, C.4    Baccino, F.5    Isidoro, C.6    Codogno, P.7
  • 70
    • 0022447864 scopus 로고
    • Use of a hydrolysable probe, [14C]lactose, to distinguish between pre-lysosomal and lysosomal steps in the autophagic pathway
    • HØYVIK, H., GORDON, P. B. & SEGLEN, P. O. (1986) Use of a hydrolysable probe, [14C]lactose, to distinguish between pre-lysosomal and lysosomal steps in the autophagic pathway. Exp. Cell Res. 166, 1-14.
    • (1986) Exp. Cell Res. , vol.166 , pp. 1-14
    • Høyvik, H.1    Gordon, P.B.2    Seglen, P.O.3
  • 71
    • 0025858399 scopus 로고
    • Inhibition of autophagic-lysosomal delivery and autophagic lactolysis by asparagine
    • HØYVIK, H., GORDON, P. B., BERG, T. O., STRØMHAUG, P. E. & SEGLEN, P. O (1991) Inhibition of autophagic-lysosomal delivery and autophagic lactolysis by asparagine. J. Cell Biol. 113, 1305-12.
    • (1991) J. Cell Biol. , vol.113 , pp. 1305-1312
    • Høyvik, H.1    Gordon, P.B.2    Berg, T.O.3    Strømhaug, P.E.4    Seglen, P.O.5
  • 72
    • 0026584608 scopus 로고
    • Isolation and some properties of a 34-kDa-membrane protein that may be responsible for ribosome binding in rat liver rough microsomes
    • ICHIMURA, T., OHSUMI, T., SHINDO, Y., OHWADA, T., YAGAME, H., MOMOSE, Y., OMATA, S. & SUGANO, H. (1992) Isolation and some properties of a 34-kDa-membrane protein that may be responsible for ribosome binding in rat liver rough microsomes. FEBS Lett. 296, 7-10.
    • (1992) FEBS Lett. , vol.296 , pp. 7-10
    • Ichimura, T.1    Ohsumi, T.2    Shindo, Y.3    Ohwada, T.4    Yagame, H.5    Momose, Y.6    Omata, S.7    Sugano, H.8
  • 73
    • 0028207001 scopus 로고
    • Rapamycin selectively represses translation of the 'polypyrimidine tract' mRNA family
    • JEFFERIES, H. B. J., REINHARD, C., KOZMA, S. C. & THOMAS, G. (1994) Rapamycin selectively represses translation of the 'polypyrimidine tract' mRNA family. Proc. Natl. Acad. Sci. USA 91, 4441-5.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 4441-4445
    • Jefferies, H.B.J.1    Reinhard, C.2    Kozma, S.C.3    Thomas, G.4
  • 74
    • 0029067696 scopus 로고
    • Ubiquitin and the enigma of intracellular protein degradation
    • JENNISSEN, H. P. (1995) Ubiquitin and the enigma of intracellular protein degradation. Eur. J. Biochem. 231, 1-30.
    • (1995) Eur. J. Biochem. , vol.231 , pp. 1-30
    • Jennissen, H.P.1
  • 75
    • 0029151540 scopus 로고
    • Phosphatidylinositol 3-kinase activity is required for early endosome fusion
    • JONES, A. T. & CLAGUE, M. J. (1995) Phosphatidylinositol 3-kinase activity is required for early endosome fusion. Biochem. J. 311, 31-4.
    • (1995) Biochem. J. , vol.311 , pp. 31-34
    • Jones, A.T.1    Clague, M.J.2
  • 76
    • 0028107099 scopus 로고
    • De novo autophagic vacuole formation in hepatocytes permeabilized by Staphylococcus aureus α-toxin. Inhibition by nonhydrolysable GTP analogs
    • KADOWAKI, M., VENERANDO, R., MIOTTO, G. & MORTIMORE, G E. (1994) De novo autophagic vacuole formation in hepatocytes permeabilized by Staphylococcus aureus α-toxin. Inhibition by nonhydrolysable GTP analogs. J. Biol. Chem. 269, 3703-10.
    • (1994) J. Biol. Chem. , vol.269 , pp. 3703-3710
    • Kadowaki, M.1    Venerando, R.2    Miotto, G.3    Mortimore, G.E.4
  • 77
    • 0027953913 scopus 로고
    • Binding of ribosomes to the rough endoplasmic reticulum mediated by the Sec61p-complex
    • KALIES, K.-U., GÖRLICH, D. & RAPOPORT, T. A. (1994) Binding of ribosomes to the rough endoplasmic reticulum mediated by the Sec61p-complex. J. Cell Biol. 126, 925-34.
    • (1994) J. Cell Biol. , vol.126 , pp. 925-934
    • Kalies, K.-U.1    Görlich, D.2    Rapoport, T.A.3
  • 78
    • 0027412618 scopus 로고
    • Insulin-stimulated phosphatidyl-inositol 3-kinase. Association with a 185-kDa tyrosine phosphorylated protein (IRS-1) and localization in a low density membrane vesicle
    • KELLY, K. L. & RUDERMAN, N. B. (1993) Insulin-stimulated phosphatidyl-inositol 3-kinase. Association with a 185-kDa tyrosine phosphorylated protein (IRS-1) and localization in a low density membrane vesicle. J. Biol. Chem. 268, 4391-8.
    • (1993) J. Biol. Chem. , vol.268 , pp. 4391-4398
    • Kelly, K.L.1    Ruderman, N.B.2
  • 80
    • 0020584354 scopus 로고
    • Sequestration of cytoplasmic enzymes in autophagic vacuole-lysosomal system induced by injection with leupeptin
    • KOMINAMI, E., HASHIDA, S., KHAIRALLAH, E. A. & KATUNUMA, N. (1983) Sequestration of cytoplasmic enzymes in autophagic vacuole-lysosomal system induced by injection with leupeptin. J. Biol. Chem. 258, 6093-100.
    • (1983) J. Biol. Chem. , vol.258 , pp. 6093-6100
    • Kominami, E.1    Hashida, S.2    Khairallah, E.A.3    Katunuma, N.4
  • 81
    • 0025051251 scopus 로고
    • Nonselective autophagy of cytosolic enzymes by isolated rat hepatocytes
    • KOPITZ, J., KISEN, G. Ø., GORDON, P. B., BOHLEY, P. & SEGLEN, P. O. (1990) Nonselective autophagy of cytosolic enzymes by isolated rat hepatocytes. J. Cell Biol. 111, 941-53.
    • (1990) J. Cell Biol. , vol.111 , pp. 941-953
    • Kopitz, J.1    Kisen, G.Ø.2    Gordon, P.B.3    Bohley, P.4    Seglen, P.O.5
  • 82
    • 0019417043 scopus 로고
    • Inhibition of autophagic vacuole formation and protein degradation by amino acids in isolated rat hepatocytes
    • KOVÁCS, A. L., GRINDE, B. & SEGLEN, P. O. (1981) Inhibition of autophagic vacuole formation and protein degradation by amino acids in isolated rat hepatocytes. Exp. Cell Res. 133, 431-6.
    • (1981) Exp. Cell Res. , vol.133 , pp. 431-436
    • Kovács, A.L.1    Grinde, B.2    Seglen, P.O.3
  • 83
    • 0020040519 scopus 로고
    • Accumulation of autophagosomes after inhibition of hepatocyte protein degradation by vinblastin, leupeptin or a lysosomotropic amine
    • KOVÁCS, A. L., REITH, A, & SEGLEN, P. O. (1982) Accumulation of autophagosomes after inhibition of hepatocyte protein degradation by vinblastin, leupeptin or a lysosomotropic amine. Exp. Cell Res. 137, 191-201.
    • (1982) Exp. Cell Res. , vol.137 , pp. 191-201
    • Kovács, A.L.1    Reith, A.2    Seglen, P.O.3
  • 84
    • 0026494420 scopus 로고
    • Serine/threonine kinases in the propagation of the early mitogenic response
    • KOZMA, S. C. & THOMAS, G. (1992) Serine/threonine kinases in the propagation of the early mitogenic response. Rev. Physiol. Biochem. Pharmacol. 119, 123-55.
    • (1992) Rev. Physiol. Biochem. Pharmacol. , vol.119 , pp. 123-155
    • Kozma, S.C.1    Thomas, G.2
  • 85
    • 0029938846 scopus 로고    scopus 로고
    • Protein kinase signaling pathway triggered by cell swelling is involved in the activation of glycogen synthase and acetyl-CoA carboxylase in isolated rat hepatocytes
    • KRAUSE, U., RIDER, M. H. & HUE, L. (1996) Protein kinase signaling pathway triggered by cell swelling is involved in the activation of glycogen synthase and acetyl-CoA carboxylase in isolated rat hepatocytes. J. Biol. Chem. 271, 16668-73.
    • (1996) J. Biol. Chem. , vol.271 , pp. 16668-16673
    • Krause, U.1    Rider, M.H.2    Hue, L.3
  • 86
    • 0024599971 scopus 로고
    • +, lactate and glucose fluxes during cell volume regulation in perfused rat liver
    • +, lactate and glucose fluxes during cell volume regulation in perfused rat liver. Pflügers Arch. 413, 209-16.
    • (1989) Pflügers Arch. , vol.413 , pp. 209-216
    • Lang, F.1    Stehle, T.2    Häussinger, D.3
  • 87
    • 0023665218 scopus 로고
    • Amino acid and hormonal control of macromolecular turnover in perfused rat liver. Evidence for selective autophagy
    • LARDEUX, B. R. & MORTIMORE, G. E. (1987) Amino acid and hormonal control of macromolecular turnover in perfused rat liver. Evidence for selective autophagy. J. Biol. Chem. 262, 14514-19.
    • (1987) J. Biol. Chem. , vol.262 , pp. 14514-14519
    • Lardeux, B.R.1    Mortimore, G.E.2
  • 88
    • 0025098673 scopus 로고
    • Ubiquitinated protein conjugates are specifically enriched in the lysosomal system of fibroblasts
    • LASZLO, L., DOHERTY, F. J., OSBORNE, N. U. & MAYER, R. J. (1990) Ubiquitinated protein conjugates are specifically enriched in the lysosomal system of fibroblasts. FEBS Lett. 261, 365-8.
    • (1990) FEBS Lett. , vol.261 , pp. 365-368
    • Laszlo, L.1    Doherty, F.J.2    Osborne, N.U.3    Mayer, R.J.4
  • 89
    • 0029076816 scopus 로고
    • Nascent polypeptide-associated complex protein prevents mistargeting of nascent chains to the endoplasmic reticulum
    • LAURING, B., SAKAI, H., KREIBICH, G. & WIEDMANN, M. (1995) Nascent polypeptide-associated complex protein prevents mistargeting of nascent chains to the endoplasmic reticulum. Proc. Natl. Acad. Sci. USA 92, 5411-15.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 5411-5415
    • Lauring, B.1    Sakai, H.2    Kreibich, G.3    Wiedmann, M.4
  • 90
    • 0026754019 scopus 로고
    • Autophagic vacuoles rapidly fuse with pre-existing lysosomes in cultured hepatocytes
    • LAWRENCE, B. P. & BROWN, W. J. (1992) Autophagic vacuoles rapidly fuse with pre-existing lysosomes in cultured hepatocytes. J. Cell Sci. 102, 515-26.
    • (1992) J. Cell Sci. , vol.102 , pp. 515-526
    • Lawrence, B.P.1    Brown, W.J.2
  • 91
    • 0026690834 scopus 로고
    • Ubiquitin-activating enzyme, E1, is associated with maturation of autophagic vacuoles
    • LENK, S. E., DUNN, W. A., TRAUSCH, J. S., CIECHANOVER, A. & SCHWARTZ, A. L. (1992) Ubiquitin-activating enzyme, E1, is associated with maturation of autophagic vacuoles. J. Cell Biol. 118, 301-8.
    • (1992) J. Cell Biol. , vol.118 , pp. 301-308
    • Lenk, S.E.1    Dunn, W.A.2    Trausch, J.S.3    Ciechanover, A.4    Schwartz, A.L.5
  • 94
    • 0028952161 scopus 로고
    • Muscle wasting associated with cancer cachexia is linked to an important activation of the ATP-dependent ubiquitin-mediated proteolysis
    • LLOVERA, M., GARCIA-MARTINEZ, C., AGELL, N., LOPEZ-SORIANO, F. J. & ARGILES, J. M. (1995) Muscle wasting associated with cancer cachexia is linked to an important activation of the ATP-dependent ubiquitin-mediated proteolysis. Int. J. Cancer 61, 138-41.
    • (1995) Int. J. Cancer , vol.61 , pp. 138-141
    • Llovera, M.1    Garcia-Martinez, C.2    Agell, N.3    Lopez-Soriano, F.J.4    Argiles, J.M.5
  • 95
    • 0029886654 scopus 로고    scopus 로고
    • Responses of glutamine transport in cultured rat skeletal muscle to osmotically induced changes in cell volume
    • LOW, S. Y., TAYLOR, P. M. & RENNIE, M. J. (1996) Responses of glutamine transport in cultured rat skeletal muscle to osmotically induced changes in cell volume. J. Physiol. London 492, 877-85.
    • (1996) J. Physiol. London , vol.492 , pp. 877-885
    • Low, S.Y.1    Taylor, P.M.2    Rennie, M.J.3
  • 98
    • 0028234322 scopus 로고
    • Cell swelling and the control of autophagic proteolysis in hepatocytes: Involvement of phosphorylation of ribosomal protein S6?
    • LUIKEN, J. J. F. P., BLOMMAART, E. F. C., BOON, L., VAN WOERKOM, G. M. & MEIJER, A. J. (1994) Cell swelling and the control of autophagic proteolysis in hepatocytes: involvement of phosphorylation of ribosomal protein S6? Biochem. Soc. Trans. 22, 508-11.
    • (1994) Biochem. Soc. Trans. , vol.22 , pp. 508-511
    • Luiken, J.J.F.P.1    Blommaart, E.F.C.2    Boon, L.3    Van Woerkom, G.M.4    Meijer, A.J.5
  • 99
    • 0030059716 scopus 로고    scopus 로고
    • The role of the intralysosomal pH in the control of autophagic proteolytic flux in rat hepatocytes
    • LUIKEN, J. J. F. P., AERTS, J. M. F. G. & MEIJER, A. J. (1996) The role of the intralysosomal pH in the control of autophagic proteolytic flux in rat hepatocytes. Eur. J. Biochem. 235, 564-73.
    • (1996) Eur. J. Biochem. , vol.235 , pp. 564-573
    • Luiken, J.J.F.P.1    Aerts, J.M.F.G.2    Meijer, A.J.3
  • 100
    • 0023202836 scopus 로고
    • Cytochrome P-450 and NADPH-cytochrome P-450 reductase are degraded in the autolysosomes in rat liver
    • MASAKI, R., YAMAMOTO, A. & TASHIRO, Y. (1987) Cytochrome P-450 and NADPH-cytochrome P-450 reductase are degraded in the autolysosomes in rat liver. J. Cell Biol. 104, 1207-15.
    • (1987) J. Cell Biol. , vol.104 , pp. 1207-1215
    • Masaki, R.1    Yamamoto, A.2    Tashiro, Y.3
  • 101
    • 0022491780 scopus 로고
    • Intracellular protein catabolism: State of the art
    • MAYER, R. J. & DOHERTY, F. (1986) Intracellular protein catabolism: state of the art. FEBS Lett. 198, 181-93.
    • (1986) FEBS Lett. , vol.198 , pp. 181-193
    • Mayer, R.J.1    Doherty, F.2
  • 103
    • 0029000181 scopus 로고
    • Increase in levels of polyubiquitin and proteasome mRNA in skeletal muscle during starvation and denervation atrophy
    • MEDINA, R., WING, S. S. & GOLDBERG, A. L. (1995) Increase in levels of polyubiquitin and proteasome mRNA in skeletal muscle during starvation and denervation atrophy. Biochem. J. 307, 631-7.
    • (1995) Biochem. J. , vol.307 , pp. 631-637
    • Medina, R.1    Wing, S.S.2    Goldberg, A.L.3
  • 104
    • 0029645963 scopus 로고
    • Inhibition of autophagic proteolysis by cell swelling in hepatocytes
    • MEIJER, A. J. (1995) Inhibition of autophagic proteolysis by cell swelling in hepatocytes. Biochem. J. 312, 987-8.
    • (1995) Biochem. J. , vol.312 , pp. 987-988
    • Meijer, A.J.1
  • 105
    • 0025361955 scopus 로고
    • Nitrogen metabolism and ornithine cycle function
    • MEIJER, A. J., LAMERS, W. H. & CHAMULEAU, R. A. F. M. (1990) Nitrogen metabolism and ornithine cycle function. Physiol. Rev. 70, 701-48.
    • (1990) Physiol. Rev. , vol.70 , pp. 701-748
    • Meijer, A.J.1    Lamers, W.H.2    Chamuleau, R.A.F.M.3
  • 108
    • 0023546546 scopus 로고
    • Calcium-dependent proteases: An enzyme system active at cellular membranes?
    • MELLGREN, K. L. (1987) Calcium-dependent proteases: an enzyme system active at cellular membranes? FASEB J. 1, 110-5.
    • (1987) FASEB J. , vol.1 , pp. 110-115
    • Mellgren, K.L.1
  • 109
    • 0026566936 scopus 로고
    • Control of hepatic proteolysis by leucine and isovaleryl-L-carnitine through a common locus. Evidence for a possible mechanism of recognition at the plasma membrane
    • MIOTTO, G., VENERANDO, R., KHURANA, K. K., SILIPRANDI, N. & MORTIMORE, G. E. (1992) Control of hepatic proteolysis by leucine and isovaleryl-L-carnitine through a common locus. Evidence for a possible mechanism of recognition at the plasma membrane. J. Biol. Chem. 267, 22066-72.
    • (1992) J. Biol. Chem. , vol.267 , pp. 22066-22072
    • Miotto, G.1    Venerando, R.2    Khurana, K.K.3    Siliprandi, N.4    Mortimore, G.E.5
  • 111
    • 0028908804 scopus 로고
    • Activation of pp70/85 S6 kinases in interleukin-2-responsive lymphoid cells is mediated by phosphatidylinositol 3-kinase and inhibited by cyclic AMP
    • MONFAR, M., LEMON, K. P., GRAMMER, T. C., CHEATHAM, L., CHUNG, J., VLAHOS, C. J. & BLENIS, J. (1995) Activation of pp70/85 S6 kinases in interleukin-2-responsive lymphoid cells is mediated by phosphatidylinositol 3-kinase and inhibited by cyclic AMP. Mol. Cell. Biol. 15, 326-37.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 326-337
    • Monfar, M.1    Lemon, K.P.2    Grammer, T.C.3    Cheatham, L.4    Chung, J.5    Vlahos, C.J.6    Blenis, J.7
  • 112
    • 0027773079 scopus 로고
    • Stimulation of translation in 3T3-L1 cells in response to insulin and phorbol ester is directly correlated with increased phosphate labelling of initiation factor (eiF-)4F and ribosomal protein S6
    • MORLEY, S. J. & TRAUGH, J. A. (1993) Stimulation of translation in 3T3-L1 cells in response to insulin and phorbol ester is directly correlated with increased phosphate labelling of initiation factor (eiF-)4F and ribosomal protein S6. Biochimie 75, 985-9.
    • (1993) Biochimie , vol.75 , pp. 985-989
    • Morley, S.J.1    Traugh, J.A.2
  • 113
    • 0020510501 scopus 로고
    • Quantitative correlation between proteolysis and macro- and microautophagy in mouse hepatocytes during starvation and refeeding
    • MORTIMORE, G. E., HUTSON, N. J. & SURMACZ, C. A. (1983) Quantitative correlation between proteolysis and macro- and microautophagy in mouse hepatocytes during starvation and refeeding. Proc. Natl. Acad. Sci. USA 80, 2179-83.
    • (1983) Proc. Natl. Acad. Sci. USA , vol.80 , pp. 2179-2183
    • Mortimore, G.E.1    Hutson, N.J.2    Surmacz, C.A.3
  • 114
    • 0023646042 scopus 로고
    • Multiphasic control of hepatic protein degradation by regulatory amino acids. General features and hormonal regulation
    • MORTIMORE, G. E., PÖSÖ, A. R., KADOWAKI, M. & WERT, J. J. JR. (1987) Multiphasic control of hepatic protein degradation by regulatory amino acids. General features and hormonal regulation. J. Biol. Chem. 262, 16322-7.
    • (1987) J. Biol. Chem. , vol.262 , pp. 16322-16327
    • Mortimore, G.E.1    Pösö, A.R.2    Kadowaki, M.3    Wert Jr., J.J.4
  • 115
    • 0023858711 scopus 로고
    • Regulation of microautophagy and basal protein turnover in rat liver. Effects of short-term starvation
    • MORTIMORE, G. E., LARDEUX, B. R. & ADAMS, C. E. (1988a) Regulation of microautophagy and basal protein turnover in rat liver. Effects of short-term starvation. J. Biol. Chem. 263, 2506-12.
    • (1988) J. Biol. Chem. , vol.263 , pp. 2506-2512
    • Mortimore, G.E.1    Lardeux, B.R.2    Adams, C.E.3
  • 116
    • 0024232662 scopus 로고
    • Modulation of the amino acid control of hepatic protein degradation by caloric deprivation
    • MORTIMORE, G. E., WERT, J. J. & ADAMS, C. E. (1988b) Modulation of the amino acid control of hepatic protein degradation by caloric deprivation. J. Biol. Chem. 263, 19545-51.
    • (1988) J. Biol. Chem. , vol.263 , pp. 19545-19551
    • Mortimore, G.E.1    Wert, J.J.2    Adams, C.E.3
  • 118
    • 0026027591 scopus 로고
    • Amino acid control of proteolysis in perfused livers of synchronously fed rats
    • MORTIMORE, G. E., KHURANA, K. K. & MIOTTO, G. (1991) Amino acid control of proteolysis in perfused livers of synchronously fed rats. J. Biol. Chem. 266, 1021-8.
    • (1991) J. Biol. Chem. , vol.266 , pp. 1021-1028
    • Mortimore, G.E.1    Khurana, K.K.2    Miotto, G.3
  • 120
    • 0029351229 scopus 로고
    • Ubiquitin in homeostasis, development and disease
    • MULLER, S. & SCHWARTZ, L. M. (1995) Ubiquitin in homeostasis, development and disease. BioEssays 17, 677-84.
    • (1995) BioEssays , vol.17 , pp. 677-684
    • Muller, S.1    Schwartz, L.M.2
  • 121
    • 0027535742 scopus 로고
    • Activation of the zeta isozyme of protein kinase C by phosphatidylinositol 3,4,5-trisphosphate
    • NAKANISHI, H. N., BREWER, K. A. & EXTON, J. H. (1993) Activation of the zeta isozyme of protein kinase C by phosphatidylinositol 3,4,5-trisphosphate. J. Biol. Chem. 268, 13-16.
    • (1993) J. Biol. Chem. , vol.268 , pp. 13-16
    • Nakanishi, H.N.1    Brewer, K.A.2    Exton, J.H.3
  • 122
    • 0029788522 scopus 로고    scopus 로고
    • Phorbol esters stimulate phosphatidylinositol 3,4,5-trisphosphate production in 3T3-L1 adipocytes - Implications for stimulation of glucose transport
    • NAVÉ, B. T., SIDDLE, K. & SHEPHERD, P. R. (1996) Phorbol esters stimulate phosphatidylinositol 3,4,5-trisphosphate production in 3T3-L1 adipocytes - implications for stimulation of glucose transport. Biochem. J. 318, 203-5.
    • (1996) Biochem. J. , vol.318 , pp. 203-205
    • Navé, B.T.1    Siddle, K.2    Shepherd, P.R.3
  • 123
    • 0029931135 scopus 로고    scopus 로고
    • Glutamine nutrition and metabolism: Where do we go from here?
    • NEU, J., SHENOY, V. & CHAKRABARTI, R. (1996) Glutamine nutrition and metabolism: where do we go from here? FASEB J. 10, 829-37.
    • (1996) FASEB J. , vol.10 , pp. 829-837
    • Neu, J.1    Shenoy, V.2    Chakrabarti, R.3
  • 124
    • 0026451081 scopus 로고
    • Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C
    • NISHIZUKA, Y. (1992) Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C. Science 258, 607-14.
    • (1992) Science , vol.258 , pp. 607-614
    • Nishizuka, Y.1
  • 127
    • 0027743432 scopus 로고
    • Molecular cloning and subcellular localization of three GTP-binding proteins of the Rab subfamily
    • OLKKONEN, V. M., DUPREE, P., KILLISCH, I., LUTCKE, A., ZERIAL, M. & SIMONS, K. (1993) Molecular cloning and subcellular localization of three GTP-binding proteins of the Rab subfamily. J. Cell Sci. 106, 1249-61.
    • (1993) J. Cell Sci. , vol.106 , pp. 1249-1261
    • Olkkonen, V.M.1    Dupree, P.2    Killisch, I.3    Lutcke, A.4    Zerial, M.5    Simons, K.6
  • 128
    • 0023654289 scopus 로고
    • Phosphorylation of ribosomal protein S6 by cAMP dependent protein kinase and mitogen-stimulated S6 kinase differentially alters translation of globin mRNA
    • PALEN, E. & TRAUGH, J. A. (1987) Phosphorylation of ribosomal protein S6 by cAMP dependent protein kinase and mitogen-stimulated S6 kinase differentially alters translation of globin mRNA. J. Biol. Chem. 262, 3518-23.
    • (1987) J. Biol. Chem. , vol.262 , pp. 3518-3523
    • Palen, E.1    Traugh, J.A.2
  • 129
    • 0016267133 scopus 로고
    • Effect of glucagon:insulin ratios on hepatic metabolism
    • PARRILLA, R., GOODMAN, M. N. & TOEWS, C. J. (1974) Effect of glucagon:insulin ratios on hepatic metabolism. Diabetes 23, 725-31.
    • (1974) Diabetes , vol.23 , pp. 725-731
    • Parrilla, R.1    Goodman, M.N.2    Toews, C.J.3
  • 130
    • 0015216852 scopus 로고
    • Mitochondrial ultrastructure in Reye's syndrome (encephalopathy and fatty degeneration of the viscera)
    • PARTIN, J., SCHUBERT, W. K. & PARTIN, J. S. (1971) Mitochondrial ultrastructure in Reye's syndrome (encephalopathy and fatty degeneration of the viscera). N. Engl. J. Med. 285, 1339-43.
    • (1971) N. Engl. J. Med. , vol.285 , pp. 1339-1343
    • Partin, J.1    Schubert, W.K.2    Partin, J.S.3
  • 131
    • 0017139166 scopus 로고
    • The role of enzyme degradation in enzyme turnover during tissue differentiation
    • PASKIN, N. & MAYER, R. J. (1977) The role of enzyme degradation in enzyme turnover during tissue differentiation. Biochim. Biophys. Acta 474, 1-10.
    • (1977) Biochim. Biophys. Acta , vol.474 , pp. 1-10
    • Paskin, N.1    Mayer, R.J.2
  • 132
    • 0003150311 scopus 로고
    • Functional morphology of the lysosomal apparatus
    • edited by Glaumann, H. & Ballard, F. J., London: Academic Press
    • PFEIFER, U. (1987) Functional morphology of the lysosomal apparatus. In Lysosomes, their role in protein breakdown (edited by Glaumann, H. & Ballard, F. J.), pp. 4-59. London: Academic Press.
    • (1987) Lysosomes, Their Role in Protein Breakdown , pp. 4-59
    • Pfeifer, U.1
  • 133
    • 0017816161 scopus 로고
    • Inhibition by insulin of the formation of autophagic vacuoles. A morphometric approach to the kinetics of intracellular degradation by autophagy
    • PFEIFER, U., WERDE, E. & BERGEEST, H. (1978) Inhibition by insulin of the formation of autophagic vacuoles. A morphometric approach to the kinetics of intracellular degradation by autophagy. J. Cell. Biol. 78, 152-67.
    • (1978) J. Cell. Biol. , vol.78 , pp. 152-167
    • Pfeifer, U.1    Werde, E.2    Bergeest, H.3
  • 135
    • 0024545981 scopus 로고
    • Energy dependence of different steps in the autophagic-lysosomal pathway
    • PLOMP, P. J. A. M., GORDON, P. B., MEIJER, A. J., HØYVIK, H. & SEGLEN, P. O. (1989) Energy dependence of different steps in the autophagic-lysosomal pathway. J. Biol. Chem. 254, 6699-704.
    • (1989) J. Biol. Chem. , vol.254 , pp. 6699-6704
    • Plomp, P.J.A.M.1    Gordon, P.B.2    Meijer, A.J.3    Høyvik, H.4    Seglen, P.O.5
  • 136
    • 0021136882 scopus 로고
    • Requirement for alanine in the amino acid control of deprivation induced protein degradation in liver
    • PÖSÖ, A. R. & MORTIMORE, G. E. (1984) Requirement for alanine in the amino acid control of deprivation induced protein degradation in liver. Proc. Natl. Acad. Sci. USA 81, 4270-4.
    • (1984) Proc. Natl. Acad. Sci. USA , vol.81 , pp. 4270-4274
    • Pösö, A.R.1    Mortimore, G.E.2
  • 137
    • 0029915031 scopus 로고    scopus 로고
    • P70 S6 kinase: An enigma with variations
    • PROUD, C. G. (1996) p70 S6 kinase: an enigma with variations. Trends Biochem Sci 21, 181-5.
    • (1996) Trends Biochem Sci , vol.21 , pp. 181-185
    • Proud, C.G.1
  • 139
  • 140
    • 0022520991 scopus 로고
    • Characteristics of a glutamine carrier in skeletal muscle have important consequences for nitrogen loss in injury, infection and chronic disease
    • RENNIE, M. J., BABIJ, P., TAYLOR, P. M., HUNDAL, H. S., MCLENNAN, P., WATT, P. W., JEPSON, M. M. & MILLWARD, R. J. (1986) Characteristics of a glutamine carrier in skeletal muscle have important consequences for nitrogen loss in injury, infection and chronic disease. Lancet 2, 1008-12.
    • (1986) Lancet , vol.2 , pp. 1008-1012
    • Rennie, M.J.1    Babij, P.2    Taylor, P.M.3    Hundal, H.S.4    Mclennan, P.5    Watt, P.W.6    Jepson, M.M.7    Millward, R.J.8
  • 141
    • 0017257079 scopus 로고
    • Attachment of ribosomes to endoplasmic membranes in mouse pancreas. Degranulation in vivo caused by the inducers of autophagocytosis neutral red, vinblastine, puromycin, and cadmium ions, and prevention by cycloheximide
    • RÉZ, G., KISS, A., BUSECK, M. J. & KOVÁCS, J. (1976) Attachment of ribosomes to endoplasmic membranes in mouse pancreas. Degranulation in vivo caused by the inducers of autophagocytosis neutral red, vinblastine, puromycin, and cadmium ions, and prevention by cycloheximide. Chem. Biol. Interactions 13, 77-87.
    • (1976) Chem. Biol. Interactions , vol.13 , pp. 77-87
    • Réz, G.1    Kiss, A.2    Buseck, M.J.3    Kovács, J.4
  • 142
    • 0028088153 scopus 로고
    • Calpain: New perspectives in molecular diversity and physiological-pathological involvement
    • SAIDO, T. C., SORIMACHI, H. & SUZUKI, K. (1994) Calpain: new perspectives in molecular diversity and physiological-pathological involvement. FASEB J. 8, 814-22.
    • (1994) FASEB J. , vol.8 , pp. 814-822
    • Saido, T.C.1    Sorimachi, H.2    Suzuki, K.3
  • 143
    • 0024678021 scopus 로고
    • Lysosomal movements during heterophagy and autophagy: With special reference to nematolysosome and wrapping lysosome
    • SAKAI, M., ARAKI, N. & OGAWA, K. (1989) Lysosomal movements during heterophagy and autophagy: with special reference to nematolysosome and wrapping lysosome. J. Electron Microsc. Tech. 12, 101-31.
    • (1989) J. Electron Microsc. Tech. , vol.12 , pp. 101-131
    • Sakai, M.1    Araki, N.2    Ogawa, K.3
  • 144
    • 0027389170 scopus 로고
    • 180-kD ribosome receptor is essential for both ribosome binding and protein translocation
    • SAVITZ, A. J. & MEYER, D. I. (1993) 180-kD ribosome receptor is essential for both ribosome binding and protein translocation. J. Cell Biol. 120, 853-63.
    • (1993) J. Cell Biol. , vol.120 , pp. 853-863
    • Savitz, A.J.1    Meyer, D.I.2
  • 145
    • 0026070404 scopus 로고
    • Energy depletion and autophagy. Cytochemical and biochemical studies in isolated rat hepatocytes
    • SCHELLENS, J. P. M. & MEIJER, A. J. (1991) Energy depletion and autophagy. Cytochemical and biochemical studies in isolated rat hepatocytes. Histochem. J. 23, 460-6.
    • (1991) Histochem. J. , vol.23 , pp. 460-466
    • Schellens, J.P.M.1    Meijer, A.J.2
  • 146
    • 0028815630 scopus 로고
    • Catabolite inactivation of fructose-1,6-bisphosphatase of Saccharomyces cerevisiae. Degradation occurs via the ubiquitin pathway
    • SCHORK, S. M., THUMM, M. & WOLF, D. H. (1995) Catabolite inactivation of fructose-1,6-bisphosphatase of Saccharomyces cerevisiae. Degradation occurs via the ubiquitin pathway. J. Biol. Chem. 270, 26446-50.
    • (1995) J. Biol. Chem. , vol.270 , pp. 26446-26450
    • Schork, S.M.1    Thumm, M.2    Wolf, D.H.3
  • 147
    • 0029013875 scopus 로고
    • Characterization of the swelling-induced alkalinization of endocytotic vesicles in fluorescein isothiocyanate-dextran-loaded rat hepatocytes
    • SCHREIBER, R. & HÄUSSINGER, D. (1995) Characterization of the swelling-induced alkalinization of endocytotic vesicles in fluorescein isothiocyanate-dextran-loaded rat hepatocytes. Biochem. J. 309, 19-24.
    • (1995) Biochem. J. , vol.309 , pp. 19-24
    • Schreiber, R.1    Häussinger, D.2
  • 148
    • 0030000362 scopus 로고    scopus 로고
    • Regulation of vesicular pH in liver macrophages and parenchymal cells by ammonia and anisotonicity as assessed by fluorescein isothiocyanate-dextran fluorescence
    • SCHREIBER, R., ZHANG, F. & HÄUSSINGER, D. (1996) Regulation of vesicular pH in liver macrophages and parenchymal cells by ammonia and anisotonicity as assessed by fluorescein isothiocyanate-dextran fluorescence. Biochem. J. 315, 385-92.
    • (1996) Biochem. J. , vol.315 , pp. 385-392
    • Schreiber, R.1    Zhang, F.2    Häussinger, D.3
  • 149
    • 0027905021 scopus 로고
    • Phosphatidy-linositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting
    • SCHU, P. V., TAKEGAWA, K., FRY, M. J., STACK, J. H., WATERFIELD, M. D. & EMR, S. D. (1993) Phosphatidy-linositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting. Science 260, 88-91.
    • (1993) Science , vol.260 , pp. 88-91
    • Schu, P.V.1    Takegawa, K.2    Fry, M.J.3    Stack, J.H.4    Waterfield, M.D.5    Emr, S.D.6
  • 150
    • 0024094086 scopus 로고
    • Immunoelectron microscopic localization of ubiquitin in hepatoma cells
    • SCHWARTZ, A. L., CIECHANOVER, A., BRANDT, R. A. & GEUZE, H. J. (1988) Immunoelectron microscopic localization of ubiquitin in hepatoma cells. EMBO J. 7, 2961-6.
    • (1988) EMBO J. , vol.7 , pp. 2961-2966
    • Schwartz, A.L.1    Ciechanover, A.2    Brandt, R.A.3    Geuze, H.J.4
  • 151
    • 0026535391 scopus 로고
    • Stress-induced alterations in autophagic pathway: Relationship to ubiquitin system
    • SCHWARTZ, A. L., BRANDT, R. A., GEUZE, H. & CIECHANOVER, A. (1992) Stress-induced alterations in autophagic pathway: relationship to ubiquitin system. Am. J. Physiol. 262, C1031-8.
    • (1992) Am. J. Physiol. , vol.262
    • Schwartz, A.L.1    Brandt, R.A.2    Geuze, H.3    Ciechanover, A.4
  • 152
    • 0022384018 scopus 로고
    • Reduced autophagic activity, improved protein balance and enhanced in vitro survival of hepatocytes isolated from carcinogen-treated rats
    • SCHWARZE, P. E. & SEGLEN, P. O. (1985) Reduced autophagic activity, improved protein balance and enhanced in vitro survival of hepatocytes isolated from carcinogen-treated rats. Exp. Cell Res. 157, 15-28.
    • (1985) Exp. Cell Res. , vol.157 , pp. 15-28
    • Schwarze, P.E.1    Seglen, P.O.2
  • 153
    • 0018746575 scopus 로고
    • Glucagon induced autophagy and proteolysis in rat liver: Mediation by selective deprivation of intracellular amino acids
    • SCHWORER, C. M. & MORTIMORE, G. E. (1979) Glucagon induced autophagy and proteolysis in rat liver: mediation by selective deprivation of intracellular amino acids. Proc. Natl. Acad. Sci. USA 76, 3169-73.
    • (1979) Proc. Natl. Acad. Sci. USA , vol.76 , pp. 3169-3173
    • Schworer, C.M.1    Mortimore, G.E.2
  • 154
    • 0002697457 scopus 로고
    • Regulation of autophagic protein degradation in isolated liver cells
    • edited by Glaumann, H. & Ballard, F. J., London: Academic Press
    • SEGLEN, P. O (1987) Regulation of autophagic protein degradation in isolated liver cells. In Lysosomes, their Role in Protein Breakdown (edited by Glaumann, H. & Ballard, F. J.), pp. 371-414. London: Academic Press.
    • (1987) Lysosomes, Their Role in Protein Breakdown , pp. 371-414
    • Seglen, P.O.1
  • 155
    • 0026584008 scopus 로고
    • Autophagy and other vacuolar protein degradation mechanisms
    • SEGLEN, P. O. & BOHLEY, P. (1992) Autophagy and other vacuolar protein degradation mechanisms. Experientia 48, 158-72.
    • (1992) Experientia , vol.48 , pp. 158-172
    • Seglen, P.O.1    Bohley, P.2
  • 156
    • 0005677775 scopus 로고
    • 3-Methyladenine: Specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes
    • SEGLEN, P. O. & GORDON, P. B. (1982) 3-Methyladenine: specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes. Proc. Natl. Acad. Sci. USA 79, 1889-92.
    • (1982) Proc. Natl. Acad. Sci. USA , vol.79 , pp. 1889-1892
    • Seglen, P.O.1    Gordon, P.B.2
  • 157
    • 0021271399 scopus 로고
    • Amino acid control of autophagic sequestration and protein degradation
    • SEGLEN, P. O. & GORDON, P. B. (1984) Amino acid control of autophagic sequestration and protein degradation. J. Cell Biol. 99, 435-44.
    • (1984) J. Cell Biol. , vol.99 , pp. 435-444
    • Seglen, P.O.1    Gordon, P.B.2
  • 158
    • 0018927246 scopus 로고
    • Amino acid inhibition of the autophagic/lysosomal pathway of protein degradation in isolated rat hepatocytes
    • SEGLEN, P. O., GORDON, P. B. & POLI, A. (1980) Amino acid inhibition of the autophagic/lysosomal pathway of protein degradation in isolated rat hepatocytes. Biochim. Biophys. Acta 630, 103-18.
    • (1980) Biochim. Biophys. Acta , vol.630 , pp. 103-118
    • Seglen, P.O.1    Gordon, P.B.2    Poli, A.3
  • 160
    • 0028110018 scopus 로고
    • VPS34p required for yeast vacuolar protein sorting is a multiple specificity kinase that exhibits both protein kinase and phosphatidylinositol-specific PI 3-kinase activities
    • STACK, J. H. & EMR, S. D. (1994) VPS34p required for yeast vacuolar protein sorting is a multiple specificity kinase that exhibits both protein kinase and phosphatidylinositol-specific PI 3-kinase activities. J. Biol. Chem. 269, 31552-62.
    • (1994) J. Biol. Chem. , vol.269 , pp. 31552-31562
    • Stack, J.H.1    Emr, S.D.2
  • 161
    • 0024492090 scopus 로고
    • Effect of parenteral glutamine peptide supplements on muscle glutamine loss and nitrogen balance after major surgery
    • STEHLE, P., MERTENS, N., PUCHSTEIN, C. H., ZANDER, J., ALBERS, S., LAWIN, P. & FÜRST, P. (1989) Effect of parenteral glutamine peptide supplements on muscle glutamine loss and nitrogen balance after major surgery. Lancet 1, 231-3.
    • (1989) Lancet , vol.1 , pp. 231-233
    • Stehle, P.1    Mertens, N.2    Puchstein, C.H.3    Zander, J.4    Albers, S.5    Lawin, P.6    Fürst, P.7
  • 162
  • 163
    • 0027513693 scopus 로고
    • Evidence for acidity of prelysosomal autophagic/endocytic vacuoles (amphisomes)
    • STRØMHAUG, P. E. & SEGLEN, P. O. (1993) Evidence for acidity of prelysosomal autophagic/endocytic vacuoles (amphisomes). Biochem. J. 291, 115-21.
    • (1993) Biochem. J. , vol.291 , pp. 115-121
    • Strømhaug, P.E.1    Seglen, P.O.2
  • 164
    • 0025830053 scopus 로고
    • Recent progress in characterization of protein kinase cascades for phosphorylation of ribosomal protein S6
    • STURGILL, T. W. & WU, J. (1991) Recent progress in characterization of protein kinase cascades for phosphorylation of ribosomal protein S6. Biochim. Biophys. Acta 1092, 350-7.
    • (1991) Biochim. Biophys. Acta , vol.1092 , pp. 350-357
    • Sturgill, T.W.1    Wu, J.2
  • 165
    • 0026786344 scopus 로고
    • Radial movement of lysosomes along microtubules in permeabilized macrophages
    • SWANSON, J. A., LOCKE, A., ANSEL, P. & HOLLENBECK, P. J. (1992) Radial movement of lysosomes along microtubules in permeabilized macrophages. J. Cell Sci. 103, 201-9.
    • (1992) J. Cell Sci. , vol.103 , pp. 201-209
    • Swanson, J.A.1    Locke, A.2    Ansel, P.3    Hollenbeck, P.J.4
  • 166
    • 0021038243 scopus 로고
    • Different effects of amino acid deprivation on synthesis of intra- and extracellular proteins in rat hepatocytes in primary culture
    • TANAKA, K. & ICHIHARA, A. (1983) Different effects of amino acid deprivation on synthesis of intra- and extracellular proteins in rat hepatocytes in primary culture. J. Biochem. 94, 1339-48.
    • (1983) J. Biochem. , vol.94 , pp. 1339-1348
    • Tanaka, K.1    Ichihara, A.2
  • 167
    • 0028032355 scopus 로고
    • Rapamycin selectively inhibits translation of mRNAs encoding elongation factors and ribosomal proteins
    • TERADA, N., PATEL, H. R., TAKASE, K., KOHNO, K., NAIRN, A. C. & GELFAND, E. W. (1994) Rapamycin selectively inhibits translation of mRNAs encoding elongation factors and ribosomal proteins. Proc. Natl. Acad. Sci. USA 91, 11477-81.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 11477-11481
    • Terada, N.1    Patel, H.R.2    Takase, K.3    Kohno, K.4    Nairn, A.C.5    Gelfand, E.W.6
  • 168
    • 0026808914 scopus 로고
    • Protein and peptide binding and stimulation of in vitro lysosomal proteolysis by the 73-kDa heat shock cognate protein
    • TERLECKI, S. R., CHIANG, H. L., OLSON, T. S. & DICK, J. F. (1992) Protein and peptide binding and stimulation of in vitro lysosomal proteolysis by the 73-kDa heat shock cognate protein. J. Biol. Chem. 267, 9202-9.
    • (1992) J. Biol. Chem. , vol.267 , pp. 9202-9209
    • Terlecki, S.R.1    Chiang, H.L.2    Olson, T.S.3    Dick, J.F.4
  • 169
    • 0028135554 scopus 로고
    • Hsp70s and lysosomal proteolysis
    • TERLECKI, s. R. (1994) Hsp70s and lysosomal proteolysis. Experientia 50, 1021-5.
    • (1994) Experientia , vol.50 , pp. 1021-1025
    • Terlecki, S.R.1
  • 170
    • 0027379661 scopus 로고
    • Polypeptide import and degradation by isolated lysosomes
    • TERLECKl, S. R. & DICE, J. F. (1993) Polypeptide import and degradation by isolated lysosomes. J. Biol. Chem. 268, 23490-5.
    • (1993) J. Biol. Chem. , vol.268 , pp. 23490-23495
    • Terleckl, S.R.1    Dice, J.F.2
  • 171
    • 0023922528 scopus 로고
    • Regulation of protein turnover versus growth state. Studies of the mechanism of initiation of acidic vacuolar proteolysis in cells of stationary ascites hepatoma
    • TESSITORE, L., BONELLI, G., CECCHINI, G., AUTELLI, R., AMENTA, J. S. & BACCINO, F. M. (1988) Regulation of protein turnover versus growth state. Studies of the mechanism of initiation of acidic vacuolar proteolysis in cells of stationary ascites hepatoma. Biochem. J. 251, 483-90.
    • (1988) Biochem. J. , vol.251 , pp. 483-490
    • Tessitore, L.1    Bonelli, G.2    Cecchini, G.3    Autelli, R.4    Amenta, J.S.5    Baccino, F.M.6
  • 173
  • 174
    • 0028855063 scopus 로고
    • Isolation and characterization of mutants impaired in the selective degradation of peroxisomes in the yeast Hansenula polymorpha
    • TITORENKO, V. I., KKIZEK, I., HARDER, W. & VEENHUIS, M. (1995) Isolation and characterization of mutants impaired in the selective degradation of peroxisomes in the yeast Hansenula polymorpha. J. Bacteriol. 177, 357-63.
    • (1995) J. Bacteriol. , vol.177 , pp. 357-363
    • Titorenko, V.I.1    Kkizek, I.2    Harder, W.3    Veenhuis, M.4
  • 175
    • 0025362656 scopus 로고
    • In exocrine pancreas, the basolateral endocytic pathway converges with the autophagic pathway immediately after the early endosome
    • TOOZE, J., HOLLINSHEAD, M., LUDWIG, T., HOWELL, K., HOFLACK, B. & KERN, H. (1990) In exocrine pancreas, the basolateral endocytic pathway converges with the autophagic pathway immediately after the early endosome. J. Cell Biol. 111, 329-45.
    • (1990) J. Cell Biol. , vol.111 , pp. 329-345
    • Tooze, J.1    Hollinshead, M.2    Ludwig, T.3    Howell, K.4    Hoflack, B.5    Kern, H.6
  • 176
    • 0027424777 scopus 로고
    • Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae
    • TSUKADA, M. & OHSUMI, Y. (1993) Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae. FEBS Lett. 333, 169-74.
    • (1993) FEBS Lett. , vol.333 , pp. 169-174
    • Tsukada, M.1    Ohsumi, Y.2
  • 177
    • 0028855325 scopus 로고
    • Divergent modes of autophagy in the methylotrophic yeast Pichia pastoris
    • TUTTLE, D. L. & DUNN, W. A. (1995) Divergent modes of autophagy in the methylotrophic yeast Pichia pastoris. J. Cell Sci. 108, 25-35.
    • (1995) J. Cell Sci. , vol.108 , pp. 25-35
    • Tuttle, D.L.1    Dunn, W.A.2
  • 178
    • 0027207680 scopus 로고
    • Selective autophagy of peroxisomes in methylotrophic yeasts
    • TUTTLE, D. L., LEWIN, A. S. & DUNN, W. A. (1993) Selective autophagy of peroxisomes in methylotrophic yeasts. Eur. J. Cell Biol. 60, 283-90.
    • (1993) Eur. J. Cell Biol. , vol.60 , pp. 283-290
    • Tuttle, D.L.1    Lewin, A.S.2    Dunn, W.A.3
  • 179
    • 0020772844 scopus 로고
    • Degradation and turnover of peroxisomes in the yeast Hansenula polymorpha induced by selective inactivation of peroxisomal enzymes
    • VEENHUIS, M., DOUMA, A., HARDER, W. & OSUMI, M. (1983) Degradation and turnover of peroxisomes in the yeast Hansenula polymorpha induced by selective inactivation of peroxisomal enzymes. Arch. Microbiol. 134, 193-203.
    • (1983) Arch. Microbiol. , vol.134 , pp. 193-203
    • Veenhuis, M.1    Douma, A.2    Harder, W.3    Osumi, M.4
  • 180
    • 0028039504 scopus 로고
    • Multiphasic control of proteolysis by leucine and alanine in the isolated rat hepatocyte
    • VENERANDO, R., MIOTTO, G., KADOWAKI, M., SILIPRANDI, N. & MORTIMORE, G. E. (1994) Multiphasic control of proteolysis by leucine and alanine in the isolated rat hepatocyte. Am. J. Physiol. 266, C455-61.
    • (1994) Am. J. Physiol. , vol.266
    • Venerando, R.1    Miotto, G.2    Kadowaki, M.3    Siliprandi, N.4    Mortimore, G.E.5
  • 181
    • 0027495032 scopus 로고
    • Effect of cell volume on acridine orange fluorescence in hepatocytes
    • VÖLKL, H., FRIEDRICH, F., HÄUSSINGER, D. & LANG, F. (1993) Effect of cell volume on acridine orange fluorescence in hepatocytes. Biochem. J. 295, 11-14.
    • (1993) Biochem. J. , vol.295 , pp. 11-14
    • Völkl, H.1    Friedrich, F.2    Häussinger, D.3    Lang, F.4
  • 182
    • 0029645958 scopus 로고
    • Cell hydration and proteolysis control in liver
    • VOM DAHL, S. & HÄUSSINGER, D. (1995) Cell hydration and proteolysis control in liver. Biochem. J. 312, 988-9.
    • (1995) Biochem. J. , vol.312 , pp. 988-989
    • Vom Dahl, S.1    Häussinger, D.2
  • 183
    • 0029033871 scopus 로고
    • Inhibition of proteolysis by cell swelling in the liver requires intact microtubular structures
    • VOM DAHL, S., STOLL, B., GEROK, W. & HÄUSSINGER, D. (1995) Inhibition of proteolysis by cell swelling in the liver requires intact microtubular structures. Biochem. J. 308, 529-36.
    • (1995) Biochem. J. , vol.308 , pp. 529-536
    • Vom Dahl, S.1    Stoll, B.2    Gerok, W.3    Häussinger, D.4
  • 184
    • 0026702507 scopus 로고
    • Effect of phorbol esters on protein kinase C-zeta
    • WAYS, D. K., COOK, P. P., WEBSTER, C. & PARKER, P. J. (1992) Effect of phorbol esters on protein kinase C-zeta. J. Biol. Chem. 267, 4799-805.
    • (1992) J. Biol. Chem. , vol.267 , pp. 4799-4805
    • Ways, D.K.1    Cook, P.P.2    Webster, C.3    Parker, P.J.4
  • 186
    • 0020446680 scopus 로고
    • Differential phosphorylation of ribosomal protein S6 in isolated rat hepatocytes after incubation with insulin and glucagon
    • WETTENHALL, R. E. H., COHEN, P., CAUDWELL, B. & HOLLAND, R. (1982) Differential phosphorylation of ribosomal protein S6 in isolated rat hepatocytes after incubation with insulin and glucagon. FEBS Lett. 148, 207-13.
    • (1982) FEBS Lett. , vol.148 , pp. 207-213
    • Wettenhall, R.E.H.1    Cohen, P.2    Caudwell, B.3    Holland, R.4
  • 188
    • 0027460118 scopus 로고
    • Glucocorticoids activate the ATP-ubiquitin-dependent proteolytic system in skeletal muscle during fasting
    • WING, S. S. & GOLDBERG, A. L. (1993) Glucocorticoids activate the ATP-ubiquitin-dependent proteolytic system in skeletal muscle during fasting. Am. J. Physiol. 264, E668-76.
    • (1993) Am. J. Physiol. , vol.264
    • Wing, S.S.1    Goldberg, A.L.2
  • 189
    • 0025801067 scopus 로고
    • Proteins containing peptide sequences related to Lys-Phe-Glu-Arg-Gln are selectively depleted in liver and heart, but not skeletal muscle, of fasted rats
    • WING, S. S., CHIANG, H. L. GOLDBERG, A. L. & DICE, J. F. (1991) Proteins containing peptide sequences related to Lys-Phe-Glu-Arg-Gln are selectively depleted in liver and heart, but not skeletal muscle, of fasted rats. Biochem. J. 275, 165-9.
    • (1991) Biochem. J. , vol.275 , pp. 165-169
    • Wing, S.S.1    Chiang, H.L.2    Goldberg, A.L.3    Dice, J.F.4
  • 190
    • 0022522767 scopus 로고
    • Liver autophagy in the influenza B virus model of Reye's syndrome in mice
    • WOODFIN, B. M. & DAVIS, L. E. (1986) Liver autophagy in the influenza B virus model of Reye's syndrome in mice. J. Cell. Biochem. 31, 271-5.
    • (1986) J. Cell. Biochem. , vol.31 , pp. 271-275
    • Woodfin, B.M.1    Davis, L.E.2
  • 191
    • 0025217177 scopus 로고
    • Characterization of the isolation membranes and the limiting membranes of autophagosomes in rat hepatocytes by lectin cytochemistry
    • YAMAMOTO, A., MASAKI, R. & TASHIRO, Y. (1990a) Characterization of the isolation membranes and the limiting membranes of autophagosomes in rat hepatocytes by lectin cytochemistry. J. Histochem. Cytochem. 38, 573-80.
    • (1990) J. Histochem. Cytochem. , vol.38 , pp. 573-580
    • Yamamoto, A.1    Masaki, R.2    Tashiro, Y.3
  • 192
    • 0025110120 scopus 로고
    • Absence of cytochrome P-450 and presence of autolysosomal membrane antigens on the isolation membranes and autophagosomal membranes in rat hepatocytes
    • YAMAMOTO, A., MASAKI, R., FUKUI, Y. & TASHIRO, Y. (1990b) Absence of cytochrome P-450 and presence of autolysosomal membrane antigens on the isolation membranes and autophagosomal membranes in rat hepatocytes. J. Histochem. Cytochem. 38, 1571-81.
    • (1990) J. Histochem. Cytochem. , vol.38 , pp. 1571-1581
    • Yamamoto, A.1    Masaki, R.2    Fukui, Y.3    Tashiro, Y.4
  • 193
    • 0028815153 scopus 로고
    • Upstream mechanisms of glycogen synthase activation by insulin and insulin-like growth factor-I. Glycogen synthase activation is antagonized by wortmannin or LY294002 but not by rapamycin or by inhibiting p21ras
    • YAMAMOTO-HONDA, R., TOBE, K., KABURAGI, Y., UEKI, K., ASAI, S., YACHI, M., SHIROUZU, M., YODOI, J., AKANUMA, Y., YOKOYAMA, S., YAZAKI, Y. & KADOWAKI, T. (1995) Upstream mechanisms of glycogen synthase activation by insulin and insulin-like growth factor-I. Glycogen synthase activation is antagonized by wortmannin or LY294002 but not by rapamycin or by inhibiting p21ras. J. Biol. Chem. 270, 2729-34.
    • (1995) J. Biol. Chem. , vol.270 , pp. 2729-2734
    • Yamamoto-Honda, R.1    Tobe, K.2    Kaburagi, Y.3    Ueki, K.4    Asai, S.5    Yachi, M.6    Shirouzu, M.7    Yodoi, J.8    Akanuma, Y.9    Yokoyama, S.10    Yazaki, Y.11    Kadowaki, T.12
  • 194
    • 0025906619 scopus 로고
    • Phosphorylation of keratin intermediate filaments by protein kinase C, by calmodulin-dependent protein kinase and by cAMP-dependent protein kinase
    • YANO, T., TOKUI, T., NISHI, Y., NISHIZAWA, K., SHIBATA, M., KIKUCHI, K., TSUIKI, S., YAMAUCHI, T. & INAGAKI, M. (1991) Phosphorylation of keratin intermediate filaments by protein kinase C, by calmodulin-dependent protein kinase and by cAMP-dependent protein kinase. Eur. J. Biochem. 197, 281-90.
    • (1991) Eur. J. Biochem. , vol.197 , pp. 281-290
    • Yano, T.1    Tokui, T.2    Nishi, Y.3    Nishizawa, K.4    Shibata, M.5    Kikuchi, K.6    Tsuiki, S.7    Yamauchi, T.8    Inagaki, M.9
  • 195
    • 0027665459 scopus 로고
    • Lysosomes in the regulation of hormone secretion in the pituitary-adrenal gland axis
    • YI, J., ZHANG, H. X., ZHANG, L. & TANG, X. M. (1993) Lysosomes in the regulation of hormone secretion in the pituitary-adrenal gland axis. Acta Biol. Exp. Sinica 26, 221-31.
    • (1993) Acta Biol. Exp. Sinica , vol.26 , pp. 221-231
    • Yi, J.1    Zhang, H.X.2    Zhang, L.3    Tang, X.M.4
  • 196
    • 0027306022 scopus 로고
    • Formation of autophagosomes during degradation of excess peroxisomes induced by administration of dioctyl phthalate
    • YOKOTA, S. (1993) Formation of autophagosomes during degradation of excess peroxisomes induced by administration of dioctyl phthalate. Eur. J. Cell Biol. 61, 67-80.
    • (1993) Eur. J. Cell Biol. , vol.61 , pp. 67-80
    • Yokota, S.1
  • 197
    • 0000795231 scopus 로고
    • Degradation of excess peroxisomes by cellular autophagy: Immunocytochemical and biochemical analysis
    • YOKOTA, S., HIMENO, M. & KATO, K. (1994) Degradation of excess peroxisomes by cellular autophagy: immunocytochemical and biochemical analysis. Acta Histochem. Cytochem. 27, 573-9.
    • (1994) Acta Histochem. Cytochem. , vol.27 , pp. 573-579
    • Yokota, S.1    Himeno, M.2    Kato, K.3
  • 198
    • 0028842133 scopus 로고
    • Formation of autophagosomes during degradation of excess peroxisomes induced by di-(2-ethylhexyl)-phthalate treatment. III. Fusion of early autophagosomes with lysosomal compartments
    • YOKOTA, S., HIMENO, M. & KATO, K. (1995) Formation of autophagosomes during degradation of excess peroxisomes induced by di-(2-ethylhexyl)-phthalate treatment. III. Fusion of early autophagosomes with lysosomal compartments. Eur. J. Cell Biol. 66, 15-24.
    • (1995) Eur. J. Cell Biol. , vol.66 , pp. 15-24
    • Yokota, S.1    Himeno, M.2    Kato, K.3
  • 199
    • 0027730391 scopus 로고
    • Formation of autophagosomes during degradation of excess peroxisomes induced by di-(2-ethylhexyl)phthalate treatment. 2. Immunocytochemical analysis of early and late autophagosomes
    • YOKOTA, S., HIMENO, M., ROTH, J., BRADA, D. & KATO, K. (1993) Formation of autophagosomes during degradation of excess peroxisomes induced by di-(2-ethylhexyl)phthalate treatment. 2. Immunocytochemical analysis of early and late autophagosomes. Eur. J. Cell Biol. 62, 372-83.
    • (1993) Eur. J. Cell Biol. , vol.62 , pp. 372-383
    • Yokota, S.1    Himeno, M.2    Roth, J.3    Brada, D.4    Kato, K.5
  • 200
    • 0024551130 scopus 로고
    • Overall proteolysis in perfused and subfractionated chemically induced malignant hepatoma of rat: Effects of amino acids
    • YUCEL, T., AHLBERG, J. & GLAUMANN, H. (1989) Overall proteolysis in perfused and subfractionated chemically induced malignant hepatoma of rat: effects of amino acids. Exp. Mol. Pathol. 50, 38-49.
    • (1989) Exp. Mol. Pathol. , vol.50 , pp. 38-49
    • Yucel, T.1    Ahlberg, J.2    Glaumann, H.3


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