Synthesis and biological aspects of mycolic acids: An important target against Mycobacterium tuberculosis

TheScientificWorldJournal

Volumn 8, Issue , 2008, Pages 720-751

  De Souza, Marcus Vinícius Nora ^a   Ferreira, Marcelle De Lima ^a,b   Pinheiro, Alessandra Campbell ^a,c   Saraiva, Maurício Frota ^d   De Almeida, Mauro Vieira ^d   Valle, Marcelo Siqueira ^d  

^a INSTITUTO OSWALDO CRUZ   (Brazil)

^b FLUMINENSE FEDERAL UNIVERSITY   (Brazil)

^c FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^d FEDERAL UNIVERSITY OF JUIZ DE FORA   (Brazil)

Author keywords

Drug discovery; Mycolic acid; Tuberculosis

Indexed keywords

(1,3 DIOXO 1,3 DIHYDRO 2H ISOINDOL 2 YL)METHYLETHYLHEPTYLPHOSPHONATE; 1 (4 BUTYLPHENYL) 3 (4 BUTOXYPHENYL)THIOUREA; 1 (4 BUTYLPHENYL) 3 (4 PROPOXYPHENYL)THIOUREA; 6,7 DIHYDRO 2 NITRO 6 (4 TRIFLUOROMETHOXYBENZYLOXY) 5H IMIDAZO[2,1 B][1,3]OXAZINE; ARABINOGALACTAN; ETHAMBUTOL; ETHAMBUTOL DERIVATIVE; ETHIONAMIDE; ETHYL 3 PHENOXYBENZYLBUTYLPHOSPHONATE; ISONIAZID; ISONIAZID DERIVATIVE; MYCOLIC ACID; MYCOLIC ACID DERIVATIVE; NITROFURANYLAMIDE DERIVATIVE; PEPTIDOGLYCAN; PHOSPHONIC ACID DERIVATIVE; RIFAMPICIN; SQ 109; THIOLACTOMYCIN; THIOLACTOMYCIN 1; TUBERCULOSTATIC AGENT;

ACYLATION; ANTIBACTERIAL ACTIVITY; BACTERIAL CELL WALL; BACTERIAL GROWTH; BACTERIAL SURVIVAL; BROMINATION; CHEMICAL BOND; CHEMICAL MODIFICATION; CHEMICAL STRUCTURE; CYCLIZATION; DEHYDRATION; DEPROTECTION REACTION; DRUG MECHANISM; DRUG POTENCY; DRUG SOLUBILITY; ESTERIFICATION; FATTY ACID SYNTHESIS; HOST PATHOGEN INTERACTION; HUMAN; HYDROGENATION; HYDROPHOBICITY; IMMUNE SYSTEM; LIPOPHILICITY; MACROPHAGE; MINIMUM INHIBITORY CONCENTRATION; MYCOBACTERIUM SMEGMATIS; MYCOBACTERIUM TUBERCULOSIS; NEOPLASM; NONHUMAN; OXIDATION; POLYMERIZATION; REDUCTION; REVIEW; SIMMONS SMITH REACTION; STRUCTURE ANALYSIS; TUBERCULOSIS;

ANTITUBERCULAR AGENTS; DRUG DESIGN; MYCOBACTERIUM TUBERCULOSIS; MYCOLIC ACIDS;

BACTERIA (MICROORGANISMS); MYCOBACTERIUM TUBERCULOSIS;

EID: 48849107674     PISSN: None     EISSN: 1537744X     Source Type: Journal    
DOI: 10.1100/tsw.2008.99     Document Type: Review

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