Synthesis and evaluation of nitrofuranylamides as novel antituberculosis agents

Journal of Medicinal Chemistry

Volumn 47, Issue 21, 2004, Pages 5276-5283

  Tangallapally, Rajendra P ^a   Yendapally, Raghunandan ^a   Lee, Robin E ^a   Hevener, Kirk ^a   Jones, Victoria C ^b   Lenaerts, Anne J M ^b   McNeil, Michael R ^b   Wang, Yuehong ^c   Franzblau, Scott ^c   Lee, Richard E ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^b Department of Environmental and Radiological Health Sciences   (United States)

^c UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

(2,3 DIHYDROINDOL 1 YL)(5 NITROFURAN 2 YL)METHANONE; 5 BENZENESULFINYLFURAN 2 CARBOXYLIC ACID (3 METHOXYPHENYL)AMIDE; 5 BENZENESULFONYLFURAN 2 CARBOXYLIC ACID (3 METHOXYPHENYL)AMIDE; 5 NITROFURAN 2 CARBOXYLIC ACID (1 PHENYLETHYL)AMIDE; 5 NITROFURAN 2 CARBOXYLIC ACID (3 BENZYLOXYPHENYL)AMIDE; 5 NITROFURAN 2 CARBOXYLIC ACID (3 HYDROXYPHENYL)AMIDE; 5 NITROFURAN 2 CARBOXYLIC ACID (4 METHOXYBENZOTHIAZOL 2 YL)AMIDE; 5 NITROFURAN 2 CARBOXYLIC ACID (6 METHOXYPYRIMIDIN 4 YL)AMIDE; 5 NITROFURAN 2 CARBOXYLIC ACID (PYRIDIN 2 YLMETHYL)AMIDE; 5 NITROFURAN 2 CARBOXYLIC ACID 2 CHLOROBENZYLAMIDE; 5 NITROFURAN 2 CARBOXYLIC ACID 2 METHOXYBENZYLAMIDE; 5 NITROFURAN 2 CARBOXYLIC ACID 2,3 DIMETHOXYBENZYLAMIDE; 5 NITROFURAN 2 CARBOXYLIC ACID 2,4 DIMETHOXYBENZYLAMIDE; 5 NITROFURAN 2 CARBOXYLIC ACID 3 BROMOPHENYLAMIDE; 5 NITROFURAN 2 CARBOXYLIC ACID 3 CHLOROPHENYLAMIDE; 5 NITROFURAN 2 CARBOXYLIC ACID 3 FLUOROPHENYLAMIDE; 5 NITROFURAN 2 CARBOXYLIC ACID 3 METHOXYPHENYLAMIDE; 5 NITROFURAN 2 CARBOXYLIC ACID 3,4 DIMETHOXYBENZYLAMIDE; 5 NITROFURAN 2 CARBOXYLIC ACID 3,4,5 TRIMETHOXYBENZYLAMIDE; 5 NITROFURAN 2 CARBOXYLIC ACID 4 CYANOPHENYLAMIDE; 5 NITROFURAN 2 CARBOXYLIC ACID 4 METHOXYBENZYLAMIDE; 5 NITROFURAN 2 CARBOXYLIC ACID 4 METHOXYPHENYLAMIDE; 5 NITROFURAN 2 CARBOXYLIC ACID [2 (3,4 DIMETHOXYPHENYL)ETHYL]AMIDE; 5 NITROFURAN 2 CARBOXYLIC ACID [2 (4 METHOXYPHENYL)ETHYL]AMIDE; 5 NITROFURAN 2 CARBOXYLIC ACID PHENETHYLAMIDE; 5 NITROFURAN 2 CARBOXYLIC ACID PHENYLAMIDE; ISOMERASE; NITROFURANYLAMIDE DERIVATIVE; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG; URIDINE DIPHOSPHATE GALACTOSE MUTASE;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; IN VIVO STUDY; MINIMUM INHIBITORY CONCENTRATION; MOUSE; MYCOBACTERIUM; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; STRUCTURE ACTIVITY RELATION; TUBERCULOSIS;

AMIDES; ANIMALS; ANTITUBERCULAR AGENTS; DATABASES, FACTUAL; FURANS; INTRAMOLECULAR TRANSFERASES; MICE; MICE, INBRED C57BL; MICROBIAL SENSITIVITY TESTS; MYCOBACTERIUM TUBERCULOSIS; STRUCTURE-ACTIVITY RELATIONSHIP; TUBERCULOSIS, PULMONARY;

EID: 4744373628     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm049972y     Document Type: Article

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