Synthesis and antimycobacterial activity of ferrocenyl ethambutol analogues and ferrocenyl diamines

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 9, 2005, Pages 2301-2303

  Razafimahefa, Dorothée ^a,b   Ralambomanana, Dimby Andrianina ^a,b   Hammouche, Lies ^c   Pélinski, Lydie ^b   Lauvagie, Sylvia ^b   Bebear, Christiane ^c   Brocard, Jacques ^b   Maugein, Jeanne ^c  

^a Faculte de Medecine d'Antananarivo   (Madagascar)

^b UNIV LILLE   (France)

^c HAUT LÉVÊQUE HOSPITAL   (France)

Author keywords

Anti tuberculosis activity; Diamines; Diamino alcohols; Ethambutol; Ferrocene

Indexed keywords

FERROCENE DERIVATIVE;

ARTICLE; CHEMICAL PROCEDURES; CONCENTRATION RESPONSE; DRUG POTENCY; DRUG SYNTHESIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN;

MYCOBACTERIUM; MYCOBACTERIUM TUBERCULOSIS;

EID: 17144430510     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.03.004     Document Type: Article

References (13)

1. C.J.L. Murray, K. Styblo, and A. Rouillon D.T. Jamison W.H. Mosely Disease Control Priorities in Developing Countries 1993 Oxford University Press New York 233
2. World Health Organization, Report On Global Tuberculosis Control, 2000 Geneva
3. A.D. Harries, and D. Mahler TB/HIV A Clinical Manual 1996 World Health Organization Geneve
4. C. Whalen, C.R. Horsburgh, and D. Hom Am. J. Respir. Crit. Care Med. 151 1995 129
5. J. Luna-Herrera, M.V. Reddy, and P.R.J. Gangadharam Antimicrob. Agents Chemother. 39 1995 440
6. L.E. Seitz, W.J. Suling, and R.C. Reynolds J. Med. Chem. 45 2002 5604
7. C. Jagannath, M.R. Emanuele, and R.L. Hunter Int. J. Antimicrob. Agents 15 2000 55
8. J.E. Kristiansen, and L. Amaral J. Antimicrob. Chemother. 40 1997 319
9. C. Biot, G. Glorian, L.A. Maciejewski, J. Brocard, O. Domarle, G. Blampain, P. Millet, A.J. Georges, H. Abessolo, D. Dive, and J. Lebibi J. Med. Chem. 40 1997 3715
10. C. Biot Curr. Med. Chem. 3 2004 135
11. S. Picart-Goetgheluck, O. Delacroix, L. Maciejewski, and J. Brocard Synthesis 10 2000 1421
12. The compounds 6a-c were not completely dissolved in MeOH or DMSO for biological tests
13. R.E. Lee, M. Protopopova, E. Crooks, R.A. Slayden, M. Terrot, and C.E. Barry III J. Comb. Chem. 5 2003 172