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Volumn 56, Issue 13, 2008, Pages 4987-4994

Screening for nutritive peptides that modify cholesterol 7α-hydroxylase expression

Author keywords

Bile acid synthesis; Casein; Cholesterol 7 hydroxylase; Luciferase reporter gene; Soy protein

Indexed keywords

BILE ACID; CASEIN; CASEIN HYDROLYSATE; CHOLESTEROL; CHOLESTEROL 7ALPHA MONOOXYGENASE; MITOGEN ACTIVATED PROTEIN KINASE; PEPTIDE; PROTEIN HYDROLYSATE; SOYBEAN PROTEIN;

EID: 47849100385     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf072806p     Document Type: Article
Times cited : (14)

References (56)
  • 1
    • 33746102594 scopus 로고    scopus 로고
    • Regulation of lipid metabolism by soy protein and its implication in diseases mediated by lipid disorders
    • Torres, N.; Torre-Villalvazo, I.; Tovar, A. R. Regulation of lipid metabolism by soy protein and its implication in diseases mediated by lipid disorders. J. Nutr. Biochem. 2006, 17, 365-373.
    • (2006) J. Nutr. Biochem , vol.17 , pp. 365-373
    • Torres, N.1    Torre-Villalvazo, I.2    Tovar, A.R.3
  • 2
    • 0027253403 scopus 로고
    • Soybean protein diet and plasma cholesterol: From therapy to molecular mechanisms
    • Sirtori, C. R.; Even, R.; Lovati, M. R. Soybean protein diet and plasma cholesterol: From therapy to molecular mechanisms. Ann. NY. Acad. Sci. 1993, 676, 188-201.
    • (1993) Ann. NY. Acad. Sci , vol.676 , pp. 188-201
    • Sirtori, C.R.1    Even, R.2    Lovati, M.R.3
  • 3
    • 0346726203 scopus 로고    scopus 로고
    • Proteins of white lupin seed, a naturally isoflavone-poor legume, reduce cholesterolemia in rats and increase LDL receptor activity in HepG cells
    • Sirtori, C. R.; Lovati, M. R.; Manzoni, C.; Castiglioni, S.; Duranti, M.; Magni, C.; Morandi, S.; D'Agostina, A.; Arnoldi, A. Proteins of white lupin seed, a naturally isoflavone-poor legume, reduce cholesterolemia in rats and increase LDL receptor activity in HepG cells. J. Nutr. 2004, 134, 18-23.
    • (2004) J. Nutr , vol.134 , pp. 18-23
    • Sirtori, C.R.1    Lovati, M.R.2    Manzoni, C.3    Castiglioni, S.4    Duranti, M.5    Magni, C.6    Morandi, S.7    D'Agostina, A.8    Arnoldi, A.9
  • 4
    • 0037387360 scopus 로고    scopus 로고
    • Peanut consumption improves indices of cardiovascular disease risk in healthy adults
    • Alper, C. M.; Mattes, R. D. Peanut consumption improves indices of cardiovascular disease risk in healthy adults. J. Am. Coll. Nutr. 2003, 22, 133-141.
    • (2003) J. Am. Coll. Nutr , vol.22 , pp. 133-141
    • Alper, C.M.1    Mattes, R.D.2
  • 5
    • 0035956303 scopus 로고    scopus 로고
    • Legume consumption and risk of coronary heart disease in US men and women: NHANES I epidemiologic follow-up study
    • Bazzano, L. A.; He, J.; Ogden, L. G.; Loria, C.; Vupputuri, S.; Myers, L.; Whelton, P. K. Legume consumption and risk of coronary heart disease in US men and women: NHANES I epidemiologic follow-up study. Arch. Intern. Med. 2001, 161, 2573-2578.
    • (2001) Arch. Intern. Med , vol.161 , pp. 2573-2578
    • Bazzano, L.A.1    He, J.2    Ogden, L.G.3    Loria, C.4    Vupputuri, S.5    Myers, L.6    Whelton, P.K.7
  • 6
    • 0027034687 scopus 로고
    • Food legumes in human nutrition: A personal perspective
    • Deshpande, S. S. Food legumes in human nutrition: A personal perspective. Crit. Rev. Food Sci. Nutr. 1992, 32, 333-363.
    • (1992) Crit. Rev. Food Sci. Nutr , vol.32 , pp. 333-363
    • Deshpande, S.S.1
  • 7
    • 0031009803 scopus 로고    scopus 로고
    • Effects of legume consumption on serum cholesterol, biliary lipids, and sterol metabolism in humans
    • Duane, W. C. Effects of legume consumption on serum cholesterol, biliary lipids, and sterol metabolism in humans. J. Lipid Res. 1997, 38, 1120-1128.
    • (1997) J. Lipid Res , vol.38 , pp. 1120-1128
    • Duane, W.C.1
  • 8
    • 0027404994 scopus 로고
    • Comparative effects of four legume species on plasma lipids and faecal steroid excretion in hypercholesterolaemic pigs
    • Kingman, S. M.; Walker, A. F.; Low, A. G.; Sambrook, I. E.; Owen, R. W.; Cole, T. J. Comparative effects of four legume species on plasma lipids and faecal steroid excretion in hypercholesterolaemic pigs. Br. J. Nutr. 1993, 69, 409-421.
    • (1993) Br. J. Nutr , vol.69 , pp. 409-421
    • Kingman, S.M.1    Walker, A.F.2    Low, A.G.3    Sambrook, I.E.4    Owen, R.W.5    Cole, T.J.6
  • 9
    • 10044242290 scopus 로고    scopus 로고
    • Dietary raw peas (Pisum sativum L.) reduce plasma total and LDL cholesterol and hepatic esterified cholesterol in intact and ileorectal anastomosed pigs fed cholesterol-rich diets
    • Martins, J. M.; Riottot, M.; de Abreu, M. C.; Lanca, M. J.; Viegas-Crespo, A. M.; Almeida, J. A.; Freire, J. B.; Bento, O. P. Dietary raw peas (Pisum sativum L.) reduce plasma total and LDL cholesterol and hepatic esterified cholesterol in intact and ileorectal anastomosed pigs fed cholesterol-rich diets. J. Nutr. 2004, 134, 3305-3312.
    • (2004) J. Nutr , vol.134 , pp. 3305-3312
    • Martins, J.M.1    Riottot, M.2    de Abreu, M.C.3    Lanca, M.J.4    Viegas-Crespo, A.M.5    Almeida, J.A.6    Freire, J.B.7    Bento, O.P.8
  • 10
    • 0038397146 scopus 로고    scopus 로고
    • Food-derived bioactive peptides - Opportunities for designing future foods
    • Korhonen, H.; Pihlanto, A. Food-derived bioactive peptides - Opportunities for designing future foods. Curr. Pharm. Des. 2003, 9, 1297-1308.
    • (2003) Curr. Pharm. Des , vol.9 , pp. 1297-1308
    • Korhonen, H.1    Pihlanto, A.2
  • 11
    • 0030749136 scopus 로고    scopus 로고
    • Biochemical properties of regulatory peptides derived from milk proteins
    • Meisel, H. Biochemical properties of regulatory peptides derived from milk proteins. Biopolymers 1997, 43, 119-128.
    • (1997) Biopolymers , vol.43 , pp. 119-128
    • Meisel, H.1
  • 12
    • 0032861381 scopus 로고    scopus 로고
    • Bioactive peptides encrypted in milk proteins: Proteolytic activation and thropho-functional properties
    • Meisel, H.; Bockelmann, W. Bioactive peptides encrypted in milk proteins: Proteolytic activation and thropho-functional properties. Antonie Van Leeuwenhoek 1999, 76, 207-215.
    • (1999) Antonie Van Leeuwenhoek , vol.76 , pp. 207-215
    • Meisel, H.1    Bockelmann, W.2
  • 13
    • 0024825103 scopus 로고
    • Biologically active peptides in milk proteins
    • Meisel, H.; Frister, H.; Schlimme, E. Biologically active peptides in milk proteins. Z. Ernahrungswiss 1989, 28, 267-278.
    • (1989) Z. Ernahrungswiss , vol.28 , pp. 267-278
    • Meisel, H.1    Frister, H.2    Schlimme, E.3
  • 14
    • 33846953603 scopus 로고    scopus 로고
    • Yak milk casein as a functional ingredient: Preparation and identification of angiotensin-I- converting enzyme inhibitory peptides
    • Jiang, J.; Chen, S.; Ren, F.; Luo, Z.; Zeng, S. S. Yak milk casein as a functional ingredient: Preparation and identification of angiotensin-I- converting enzyme inhibitory peptides. J. Dairy Res. 2007, 74, 18-25.
    • (2007) J. Dairy Res , vol.74 , pp. 18-25
    • Jiang, J.1    Chen, S.2    Ren, F.3    Luo, Z.4    Zeng, S.S.5
  • 15
    • 0037032432 scopus 로고    scopus 로고
    • Angiotensin-I-converting enzyme inhibitory peptides from tryptic hydrolysate of bovine alphaS2-casein
    • Tauzin, J.; Miclo, L.; Gaillard, J. L. Angiotensin-I-converting enzyme inhibitory peptides from tryptic hydrolysate of bovine alphaS2-casein. FEBS Lett. 2002, 531, 369-374.
    • (2002) FEBS Lett , vol.531 , pp. 369-374
    • Tauzin, J.1    Miclo, L.2    Gaillard, J.L.3
  • 16
    • 21444434772 scopus 로고    scopus 로고
    • Optimization of angiotensin I-converting enzyme (ACE) inhibition by rice dregs hydrolysates using response surface methodology
    • He, G. Q.; Xuan, G. D.; Ruan, H.; Chen, Q. H.; Xu, Y. Optimization of angiotensin I-converting enzyme (ACE) inhibition by rice dregs hydrolysates using response surface methodology. J. Zhejiang Univ. Sci. B 2005, 6, 508-513.
    • (2005) J. Zhejiang Univ. Sci. B , vol.6 , pp. 508-513
    • He, G.Q.1    Xuan, G.D.2    Ruan, H.3    Chen, Q.H.4    Xu, Y.5
  • 17
    • 11144233214 scopus 로고    scopus 로고
    • A novel angiotensin I converting enzyme inhibitory peptide from Alaska pollack (Theragra chalcogramma) frame protein hydrolysate
    • Je, J. Y.; Park, P. J.; Kwon, J. Y.; Kim, S. K. A novel angiotensin I converting enzyme inhibitory peptide from Alaska pollack (Theragra chalcogramma) frame protein hydrolysate. J. Agric. Food Chem. 2004, 52, 7842-7845.
    • (2004) J. Agric. Food Chem , vol.52 , pp. 7842-7845
    • Je, J.Y.1    Park, P.J.2    Kwon, J.Y.3    Kim, S.K.4
  • 18
    • 33746531279 scopus 로고    scopus 로고
    • Angiotensin I-converting enzyme inhibitory peptide derived from glycinin, the 11S globulin of soybean (Glycine max)
    • Mallikarjun Gouda, K. G.; Gowda, L. R.; Rao, A. G.; Prakash, V. Angiotensin I-converting enzyme inhibitory peptide derived from glycinin, the 11S globulin of soybean (Glycine max). J. Agric. Food Chem. 2006, 54, 4568-4573.
    • (2006) J. Agric. Food Chem , vol.54 , pp. 4568-4573
    • Mallikarjun Gouda, K.G.1    Gowda, L.R.2    Rao, A.G.3    Prakash, V.4
  • 20
    • 0029820968 scopus 로고    scopus 로고
    • Peptide transporters in the intestine and the kidney
    • Leibach, F. H.; Ganapamy, V. Peptide transporters in the intestine and the kidney. Annu. Rev. Nutr. 1996, 16, 99-119.
    • (1996) Annu. Rev. Nutr , vol.16 , pp. 99-119
    • Leibach, F.H.1    Ganapamy, V.2
  • 21
    • 0035136393 scopus 로고    scopus 로고
    • Hypotensive and physiological effect of angiotensin converting enzyme inhibitory peptides derived from soy protein on spontaneously hypertensive rats
    • Wu, J.; Ding, X. Hypotensive and physiological effect of angiotensin converting enzyme inhibitory peptides derived from soy protein on spontaneously hypertensive rats. J. Agric. Food Chem. 2001, 49, 501-506.
    • (2001) J. Agric. Food Chem , vol.49 , pp. 501-506
    • Wu, J.1    Ding, X.2
  • 23
    • 0034657529 scopus 로고    scopus 로고
    • Intestinal absorption of peptides through the enterocytes
    • Ziv, E.; Bendayan, M. Intestinal absorption of peptides through the enterocytes. Microsc. Res. Tech. 2000, 49, 346-352.
    • (2000) Microsc. Res. Tech , vol.49 , pp. 346-352
    • Ziv, E.1    Bendayan, M.2
  • 24
    • 0027972645 scopus 로고
    • Biochemical and morpho-cytochemical evidence for the intestinal absorption of insulin in control and diabetic rats. Comparison between the effectiveness of duodenal and colon mucosa
    • Bendayan, M.; Ziv, E.; Gingras, D.; Ben-Sasson, R.; Bar-On, H.; Kidron, M. Biochemical and morpho-cytochemical evidence for the intestinal absorption of insulin in control and diabetic rats. Comparison between the effectiveness of duodenal and colon mucosa. Diabetologia 1994, 37, 119-126.
    • (1994) Diabetologia , vol.37 , pp. 119-126
    • Bendayan, M.1    Ziv, E.2    Gingras, D.3    Ben-Sasson, R.4    Bar-On, H.5    Kidron, M.6
  • 25
    • 0025259450 scopus 로고
    • Morpho-cytochemical and biochemical evidence for insulin absorption by the rat ileal epithelium
    • Bendayan, M.; Ziv, E.; Ben-Sasson, R.; Bar-On, H.; Kidron, M. Morpho-cytochemical and biochemical evidence for insulin absorption by the rat ileal epithelium. Diabetologia 1990, 33, 197-204.
    • (1990) Diabetologia , vol.33 , pp. 197-204
    • Bendayan, M.1    Ziv, E.2    Ben-Sasson, R.3    Bar-On, H.4    Kidron, M.5
  • 26
    • 25644446113 scopus 로고    scopus 로고
    • Assessment of cardiovascular risk-PROCAM and new algorithms
    • Assmann, G. Assessment of cardiovascular risk-PROCAM and new algorithms. Biomed. Tech. (Berlin) 2005, 50, 227-232.
    • (2005) Biomed. Tech. (Berlin) , vol.50 , pp. 227-232
    • Assmann, G.1
  • 27
    • 0036062231 scopus 로고    scopus 로고
    • Effects of high- and low-isoflavone (phytoestrogen) soy foods on inflammatory biomarkers and proinflammatory cytokines in middle-aged men and women
    • Jenkins, D. J.; Kendall, C. W.; Connelly, P. W.; Jackson, C. J.; Parker, T.; Faulkner, D.; Vidgen, E. Effects of high- and low-isoflavone (phytoestrogen) soy foods on inflammatory biomarkers and proinflammatory cytokines in middle-aged men and women. Metabolism 2002, 51, 919-924.
    • (2002) Metabolism , vol.51 , pp. 919-924
    • Jenkins, D.J.1    Kendall, C.W.2    Connelly, P.W.3    Jackson, C.J.4    Parker, T.5    Faulkner, D.6    Vidgen, E.7
  • 28
    • 0036009146 scopus 로고    scopus 로고
    • Regulation of cholesterol-7alpha-hydroxylase: BAREly missing a SHP
    • Davis, R. A.; Miyake, J. H.; Hui, T. Y.; Spann, N. J. Regulation of cholesterol-7alpha-hydroxylase: BAREly missing a SHP. J. Lipid Res. 2002, 43, 533-543.
    • (2002) J. Lipid Res , vol.43 , pp. 533-543
    • Davis, R.A.1    Miyake, J.H.2    Hui, T.Y.3    Spann, N.J.4
  • 30
    • 17244375261 scopus 로고    scopus 로고
    • Kinase/phosphatase regulation of CYP7A1
    • Stroup, D. Kinase/phosphatase regulation of CYP7A1. Front Biosci. 2005, 10, 1678-1692.
    • (2005) Front Biosci , vol.10 , pp. 1678-1692
    • Stroup, D.1
  • 31
    • 34548321724 scopus 로고    scopus 로고
    • Activation of bile acid biosynthesis by the p38 mitogen-activated protein kinase (MAPK): Hepatocyte nuclear factor-4alpha phosphorylation by the p38 MAPK is required for cholesterol 7alpha-hydroxylase expression
    • Xu, Z.; Tavares-Sanchez, O. L.; Li, Q.; Fernando, J.; Rodriguez, C. M.; Studer, E. J.; Pandak, W. M.; Hylemon, P. B.; Gil, G. Activation of bile acid biosynthesis by the p38 mitogen-activated protein kinase (MAPK): Hepatocyte nuclear factor-4alpha phosphorylation by the p38 MAPK is required for cholesterol 7alpha-hydroxylase expression. J. Biol. Chem. 2007, 282, 24607-24614.
    • (2007) J. Biol. Chem , vol.282 , pp. 24607-24614
    • Xu, Z.1    Tavares-Sanchez, O.L.2    Li, Q.3    Fernando, J.4    Rodriguez, C.M.5    Studer, E.J.6    Pandak, W.M.7    Hylemon, P.B.8    Gil, G.9
  • 32
    • 33749386425 scopus 로고    scopus 로고
    • Insulin regulation of cholesterol 7alpha-hydroxylase expression in human hepatocytes: Roles of forkhead box O1 and sterol regulatory element-binding protein Ic
    • Li, T.; Kong, X.; Owsley, E.; Ellis, E.; Strom, S.; Chiang, J. Y. Insulin regulation of cholesterol 7alpha-hydroxylase expression in human hepatocytes: Roles of forkhead box O1 and sterol regulatory element-binding protein Ic. J. Biol. Chem. 2006, 281, 28745-28754.
    • (2006) J. Biol. Chem , vol.281 , pp. 28745-28754
    • Li, T.1    Kong, X.2    Owsley, E.3    Ellis, E.4    Strom, S.5    Chiang, J.Y.6
  • 33
    • 0028965012 scopus 로고
    • Insulin suppresses bile acid synthesis in cultured rat hepatocytes by down-regulation of cholesterol 7 alpha-hydroxylase and sterol 27-hydroxylase gene transcription
    • Twisk, J.; Hoekman, M. F.; Lehmann, E. M.; Meijer, P.; Mager, W. H.; Princen, H. M. Insulin suppresses bile acid synthesis in cultured rat hepatocytes by down-regulation of cholesterol 7 alpha-hydroxylase and sterol 27-hydroxylase gene transcription. Hepatology 1995, 21, 501-510.
    • (1995) Hepatology , vol.21 , pp. 501-510
    • Twisk, J.1    Hoekman, M.F.2    Lehmann, E.M.3    Meijer, P.4    Mager, W.H.5    Princen, H.M.6
  • 34
    • 0021682572 scopus 로고
    • Cholesterol 7 alpha-hydroxylase of rat liver: An insulin sensitive enzyme
    • Subbiah, M. T.; Yunker, R. L. Cholesterol 7 alpha-hydroxylase of rat liver: An insulin sensitive enzyme. Biochem. Biophys. Res. Commun. 1984, 124, 896-902.
    • (1984) Biochem. Biophys. Res. Commun , vol.124 , pp. 896-902
    • Subbiah, M.T.1    Yunker, R.L.2
  • 35
    • 0029834337 scopus 로고    scopus 로고
    • Transcriptional regulation of the human cholesterol 7 alpha-hydroxylase gene (CYP7A) in HepG2 cells
    • Wang, D. P.; Stroup, D.; Marrapodi, M.; Crestani, M.; Galli, G.; Chiang, J. Y. Transcriptional regulation of the human cholesterol 7 alpha-hydroxylase gene (CYP7A) in HepG2 cells. J. Lipid Res. 1996, 37, 1831-1841.
    • (1996) J. Lipid Res , vol.37 , pp. 1831-1841
    • Wang, D.P.1    Stroup, D.2    Marrapodi, M.3    Crestani, M.4    Galli, G.5    Chiang, J.Y.6
  • 36
    • 47849127761 scopus 로고    scopus 로고
    • Physiological-like food protein hydrolysates: A strategy to identify peptides modulating atherosclerosis-relevant factors
    • Schoeps, R.; Koerting, R.; Nass, N.; Schmelzer, C. E. H. Physiological-like food protein hydrolysates: A strategy to identify peptides modulating atherosclerosis-relevant factors. NAFAS 2005, 3, 59-64.
    • (2005) NAFAS , vol.3 , pp. 59-64
    • Schoeps, R.1    Koerting, R.2    Nass, N.3    Schmelzer, C.E.H.4
  • 37
    • 0033434080 scopus 로고    scopus 로고
    • Probability-based protein identification by searching sequence databases using mass spectrometry data
    • Perkins, D. N.; Pappin, D. J.; Creasy, D. M.; Cottrell, J. S. Probability-based protein identification by searching sequence databases using mass spectrometry data. Electrophoresis 1999, 20, 3551-3567.
    • (1999) Electrophoresis , vol.20 , pp. 3551-3567
    • Perkins, D.N.1    Pappin, D.J.2    Creasy, D.M.3    Cottrell, J.S.4
  • 39
    • 7044222048 scopus 로고    scopus 로고
    • Mass spectrometric characterization of peptides derived by peptic cleavage of bovine beta-casein
    • Schmelzer, C. E.; Schops, R.; Ulbrich-Hofmann, R.; Neubert, R. H.; Raith, K. Mass spectrometric characterization of peptides derived by peptic cleavage of bovine beta-casein. J. Chromatogr. A 2004, 1055, 87-92.
    • (2004) J. Chromatogr. A , vol.1055 , pp. 87-92
    • Schmelzer, C.E.1    Schops, R.2    Ulbrich-Hofmann, R.3    Neubert, R.H.4    Raith, K.5
  • 40
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • Mosmann, T. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J. Immunol. Methods 1983, 65, 55-63.
    • (1983) J. Immunol. Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 41
    • 0034660683 scopus 로고    scopus 로고
    • A noncommercial dual luciferase enzyme assay system for reporter gene analysis
    • Dyer, B. W.; Ferrer, F. A.; Klinedinst, D. K.; Rodriguez, R. A noncommercial dual luciferase enzyme assay system for reporter gene analysis. Anal. Biochem. 2000, 282, 158-161.
    • (2000) Anal. Biochem , vol.282 , pp. 158-161
    • Dyer, B.W.1    Ferrer, F.A.2    Klinedinst, D.K.3    Rodriguez, R.4
  • 42
    • 1842478225 scopus 로고    scopus 로고
    • Hypotensive peptides from milk proteins
    • FitzGerald, R. J.; Murray, B. A.; Walsh, D. J. Hypotensive peptides from milk proteins. J. Nutr. 2004, 134, 980S-988S.
    • (2004) J. Nutr , vol.134
    • FitzGerald, R.J.1    Murray, B.A.2    Walsh, D.J.3
  • 43
  • 44
    • 0036712560 scopus 로고    scopus 로고
    • Tovar, A. R.; Murguia, F.; Cruz, C.; Hernandez-Pando, R.; Aguilar-Salinas, C. A.; Pedraza-Chaverri, J.; Correa-Rotter, R.; Torres, N. A soy protein diet alters hepatic lipid metabolism gene expression and reduces serum lipids and renal fibrogenic cytokines in rats with chronic nephrotic syndrome. J. Nutr. 2002, 132, 2562-2569.
    • Tovar, A. R.; Murguia, F.; Cruz, C.; Hernandez-Pando, R.; Aguilar-Salinas, C. A.; Pedraza-Chaverri, J.; Correa-Rotter, R.; Torres, N. A soy protein diet alters hepatic lipid metabolism gene expression and reduces serum lipids and renal fibrogenic cytokines in rats with chronic nephrotic syndrome. J. Nutr. 2002, 132, 2562-2569.
  • 45
    • 34247092771 scopus 로고    scopus 로고
    • Isoflavone-poor soy protein alters the lipid metabolism of rats by SREBP-mediated down-regulation of hepatic genes
    • Shukla, A.; Brandsch, C.; Bettzieche, A.; Hirche, F.; Stangl, G. I.; Eder, K. Isoflavone-poor soy protein alters the lipid metabolism of rats by SREBP-mediated down-regulation of hepatic genes. J. Nutr. Biochem. 2007, 18, 313-321.
    • (2007) J. Nutr. Biochem , vol.18 , pp. 313-321
    • Shukla, A.1    Brandsch, C.2    Bettzieche, A.3    Hirche, F.4    Stangl, G.I.5    Eder, K.6
  • 46
    • 0034518420 scopus 로고    scopus 로고
    • The role of orphan nuclear receptors in the regulation of cholesterol homeostasis
    • Repa, J. J.; Mangelsdorf, D. J. The role of orphan nuclear receptors in the regulation of cholesterol homeostasis. Annu. Rev. Cell Dev. Biol. 2000, 16, 459-481.
    • (2000) Annu. Rev. Cell Dev. Biol , vol.16 , pp. 459-481
    • Repa, J.J.1    Mangelsdorf, D.J.2
  • 47
    • 0031758285 scopus 로고    scopus 로고
    • Molecular aspects in feedback regulation of gene expression by cholesterol in mammalian cells
    • Osborne, T. F.; LaMorte, V. J. Molecular aspects in feedback regulation of gene expression by cholesterol in mammalian cells. Methods 1998, 16, 42-48.
    • (1998) Methods , vol.16 , pp. 42-48
    • Osborne, T.F.1    LaMorte, V.J.2
  • 48
    • 47849121328 scopus 로고    scopus 로고
    • Exsulins (casoinsulins): Nutrition-derived cryptic metalloregulated peptides with insulin mimicry and amyloid propensity
    • Wissler, J. H.; Georgi, G.; Luy, B.; Jennissen, H. P.; Boehm, G. Exsulins (casoinsulins): Nutrition-derived cryptic metalloregulated peptides with insulin mimicry and amyloid propensity. Mol. Biol. Cell 2002, Suppl. 13, 392a.
    • (2002) Mol. Biol. Cell , Issue.SUPPL. 13
    • Wissler, J.H.1    Georgi, G.2    Luy, B.3    Jennissen, H.P.4    Boehm, G.5
  • 49
    • 47849104654 scopus 로고    scopus 로고
    • Insulin Mimetic Amino Acid Sequences
    • European Patent EP1434797
    • Wissler, J. H.; Georgi, G.; Boehm, G. Insulin Mimetic Amino Acid Sequences. European Patent EP1434797, 2004.
    • (2004)
    • Wissler, J.H.1    Georgi, G.2    Boehm, G.3
  • 50
    • 26244441014 scopus 로고    scopus 로고
    • The farnesoid X receptor: A molecular link between bile acid and lipid and glucose metabolism
    • Claudel, T.; Staels, B.; Kuipers, F. The farnesoid X receptor: A molecular link between bile acid and lipid and glucose metabolism. Arterioscler. Thromb. Vasc. Biol. 2005, 25, 2020-2030.
    • (2005) Arterioscler. Thromb. Vasc. Biol , vol.25 , pp. 2020-2030
    • Claudel, T.1    Staels, B.2    Kuipers, F.3
  • 51
    • 0032736052 scopus 로고    scopus 로고
    • Nuclear receptor regulation of cholesterol and bile acid metabolism
    • Repa, J. J.; Mangelsdorf, D. J. Nuclear receptor regulation of cholesterol and bile acid metabolism. Curr. Opin. Biotechnol. 1999, 10, 557-563.
    • (1999) Curr. Opin. Biotechnol , vol.10 , pp. 557-563
    • Repa, J.J.1    Mangelsdorf, D.J.2
  • 52
    • 23644451052 scopus 로고    scopus 로고
    • Independent repression of bile acid synthesis and activation of c-Jun N-terminal kinase (JNK) by activated hepatocyte fibroblast growth factor receptor 4 (FGFR4) and bile acids
    • Yu, C.; Wang, F.; Jin, C.; Huang, X.; McKeehan, W. L. Independent repression of bile acid synthesis and activation of c-Jun N-terminal kinase (JNK) by activated hepatocyte fibroblast growth factor receptor 4 (FGFR4) and bile acids. J. Biol. Chem. 2005, 280, 17707-17714.
    • (2005) J. Biol. Chem , vol.280 , pp. 17707-17714
    • Yu, C.1    Wang, F.2    Jin, C.3    Huang, X.4    McKeehan, W.L.5
  • 53
    • 1242294416 scopus 로고    scopus 로고
    • Deoxycholic acid activates the c-Jun N-terminal kinase pathway via FAS receptor activation in primary hepatocytes. Role of acidic sphingomyelinase-mediated ceramide generation in FAS receptor activation
    • Gupta, S.; Natarajan, R.; Payne, S. G.; Studer, E. J.; Spiegel, S.; Dent, P.; Hylemon, P. B. Deoxycholic acid activates the c-Jun N-terminal kinase pathway via FAS receptor activation in primary hepatocytes. Role of acidic sphingomyelinase-mediated ceramide generation in FAS receptor activation. J. Biol. Chem. 2004, 279, 5821-5828.
    • (2004) J. Biol. Chem , vol.279 , pp. 5821-5828
    • Gupta, S.1    Natarajan, R.2    Payne, S.G.3    Studer, E.J.4    Spiegel, S.5    Dent, P.6    Hylemon, P.B.7
  • 54
    • 0035844156 scopus 로고    scopus 로고
    • Down-regulation of cholesterol 7alpha-hydroxylase (CYP7A1) gene expression by bile acids in primary rat hepatocytes is mediated by the c-Jun N-terminal kinase pathway
    • Gupta, S.; Stravitz, R. T.; Dent, P.; Hylemon, P. B. Down-regulation of cholesterol 7alpha-hydroxylase (CYP7A1) gene expression by bile acids in primary rat hepatocytes is mediated by the c-Jun N-terminal kinase pathway. J. Biol. Chem. 2001, 276, 15816-15822.
    • (2001) J. Biol. Chem , vol.276 , pp. 15816-15822
    • Gupta, S.1    Stravitz, R.T.2    Dent, P.3    Hylemon, P.B.4
  • 55
    • 4644353365 scopus 로고    scopus 로고
    • Bile acids induce mitochondrial ROS, which promote activation of receptor tyrosine kinases and signaling pathways in rat hepatocytes
    • Fang, Y.; Han, S. I.; Mitchell, C.; Gupta, S.; Studer, E.; Grant, S.; Hylemon, P. B.; Dent, P. Bile acids induce mitochondrial ROS, which promote activation of receptor tyrosine kinases and signaling pathways in rat hepatocytes. Hepatology 2004, 40, 961-971.
    • (2004) Hepatology , vol.40 , pp. 961-971
    • Fang, Y.1    Han, S.I.2    Mitchell, C.3    Gupta, S.4    Studer, E.5    Grant, S.6    Hylemon, P.B.7    Dent, P.8
  • 56
    • 2542418816 scopus 로고    scopus 로고
    • Insulin-activated Erk-mitogen-activated protein kinases phosphorylate sterol regulatory element-binding Protein-2 at serine residues 432 and 455 in vivo
    • Kotzka, J.; Lehr, S.; Roth, G.; Avci, H.; Knebel, B.; Muller-Wieland, D. Insulin-activated Erk-mitogen-activated protein kinases phosphorylate sterol regulatory element-binding Protein-2 at serine residues 432 and 455 in vivo. J. Biol. Chem. 2004, 279, 22404-22411.
    • (2004) J. Biol. Chem , vol.279 , pp. 22404-22411
    • Kotzka, J.1    Lehr, S.2    Roth, G.3    Avci, H.4    Knebel, B.5    Muller-Wieland, D.6


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