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Volumn 51, Issue 1, 2008, Pages 74-88

Metabolic Reserve of the Heart: The Forgotten Link Between Contraction and Coronary Flow

Author keywords

[No Author keywords available]

Indexed keywords

CARBOHYDRATE; FATTY ACID; GLUCOSE; GLYCOGEN; KETONE; LACTIC ACID; TRIACYLGLYCEROL;

EID: 46849089267     PISSN: 00330620     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pcad.2007.11.005     Document Type: Article
Times cited : (37)

References (132)
  • 1
    • 0014439187 scopus 로고
    • Cardiac muscle: activation and contraction
    • Sonnenblick E.H., and Stam Jr. A.C. Cardiac muscle: activation and contraction. Annu Rev Physiol 31 (1969) 647-674
    • (1969) Annu Rev Physiol , vol.31 , pp. 647-674
    • Sonnenblick, E.H.1    Stam Jr., A.C.2
  • 2
    • 46849106800 scopus 로고
    • Canine myocardial sarcolemma: its preparation and enzymic activity
    • Stam Jr. A.C., Weglicki W.B., Feldman J.C., et al. Canine myocardial sarcolemma: its preparation and enzymic activity. J Mol Cell Cardiol 1 (1970) 117-130
    • (1970) J Mol Cell Cardiol , vol.1 , pp. 117-130
    • Stam Jr., A.C.1    Weglicki, W.B.2    Feldman, J.C.3
  • 3
    • 0014328768 scopus 로고
    • Oxygen consumption of the heart. Newer concepts of its multifactoral determination
    • Sonneblick E.H., Ross Jr. J., and Braunwald E. Oxygen consumption of the heart. Newer concepts of its multifactoral determination. Am J Cardiol 22 (1968) 328-336
    • (1968) Am J Cardiol , vol.22 , pp. 328-336
    • Sonneblick, E.H.1    Ross Jr., J.2    Braunwald, E.3
  • 4
    • 0014502760 scopus 로고
    • The contractile state of the heart as expressed by force-velocity relations
    • Sonneblick E.H., Parmley W., and Parmley C.W. The contractile state of the heart as expressed by force-velocity relations. Am J Cardiol 23 (1969) 488-503
    • (1969) Am J Cardiol , vol.23 , pp. 488-503
    • Sonneblick, E.H.1    Parmley, W.2    Parmley, C.W.3
  • 5
    • 73849161656 scopus 로고
    • Force-velocity relations in mammalian heart muscle
    • Sonnenblick E.H. Force-velocity relations in mammalian heart muscle. Am J Physiol 202 (1962) 931-939
    • (1962) Am J Physiol , vol.202 , pp. 931-939
    • Sonnenblick, E.H.1
  • 6
    • 0000318445 scopus 로고
    • Contractile state of the heart characterized by force-velocity relations in variably afterloaded and isovolumic beats
    • Ross Jr. J., Covell J.W., Sonnenblick E.H., et al. Contractile state of the heart characterized by force-velocity relations in variably afterloaded and isovolumic beats. Circ Res 18 (1965) 149-163
    • (1965) Circ Res , vol.18 , pp. 149-163
    • Ross Jr., J.1    Covell, J.W.2    Sonnenblick, E.H.3
  • 7
    • 0014132503 scopus 로고
    • Contractile state of cardiac muscle obtained from cats with experimentally produced ventricular hypertrophy and heart failure
    • Spann Jr. J.F., Buccino R.A., Sonnenblick E.H., et al. Contractile state of cardiac muscle obtained from cats with experimentally produced ventricular hypertrophy and heart failure. Circ Res 21 (1967) 341-354
    • (1967) Circ Res , vol.21 , pp. 341-354
    • Spann Jr., J.F.1    Buccino, R.A.2    Sonnenblick, E.H.3
  • 8
    • 43949150714 scopus 로고
    • Energy metabolism of the heart: from basic concepts to clinical applications
    • Taegtmeyer H. Energy metabolism of the heart: from basic concepts to clinical applications. Curr Probl Cardiol 19 (1994) 57-116
    • (1994) Curr Probl Cardiol , vol.19 , pp. 57-116
    • Taegtmeyer, H.1
  • 9
    • 0018905978 scopus 로고
    • Evaluation of inotropic contractile reserve in ischemic heart disease using postextrasystolic potentiation
    • Cohn P.F. Evaluation of inotropic contractile reserve in ischemic heart disease using postextrasystolic potentiation. Circulation 61 (1980) 1071-1075
    • (1980) Circulation , vol.61 , pp. 1071-1075
    • Cohn, P.F.1
  • 10
    • 0033101495 scopus 로고    scopus 로고
    • Contractile reserve and coronary blood flow reserve in collateral-dependent myocardium
    • Bonow R.O. Contractile reserve and coronary blood flow reserve in collateral-dependent myocardium. J Am Coll Cardiol 33 (1999) 705-707
    • (1999) J Am Coll Cardiol , vol.33 , pp. 705-707
    • Bonow, R.O.1
  • 11
    • 0025098045 scopus 로고
    • Coronary flow reserve as a physiologic measure of stenosis severity
    • Gould K.L., Kirkeeide R.L., and Buchi M. Coronary flow reserve as a physiologic measure of stenosis severity. J Am Coll Cardiol 15 (1990) 459-474
    • (1990) J Am Coll Cardiol , vol.15 , pp. 459-474
    • Gould, K.L.1    Kirkeeide, R.L.2    Buchi, M.3
  • 12
    • 0033954579 scopus 로고    scopus 로고
    • Prognostic implications of myocardial contractile reserve in patients with ischemic cardiomyopathy
    • Galatro K., and Chaudhry F.A. Prognostic implications of myocardial contractile reserve in patients with ischemic cardiomyopathy. Echocardiography 17 (2000) 61-67
    • (2000) Echocardiography , vol.17 , pp. 61-67
    • Galatro, K.1    Chaudhry, F.A.2
  • 13
    • 3042711537 scopus 로고    scopus 로고
    • Linking gene expression to function: metabolic flexibility in the normal and diseased heart
    • Taegtmeyer H., Golfman L., Sharma S., et al. Linking gene expression to function: metabolic flexibility in the normal and diseased heart. Ann N Y Acad Sci 1015 (2004) 202-213
    • (2004) Ann N Y Acad Sci , vol.1015 , pp. 202-213
    • Taegtmeyer, H.1    Golfman, L.2    Sharma, S.3
  • 14
    • 46849106141 scopus 로고    scopus 로고
    • Newsholme EA, Leech L, Duester G: Fuel management. In: Keep on running: the science of training and performance. pp. 95-112. West Sussex, UK: John Wiley & Sons, Ltd., 1994 pp. 95-11.
    • Newsholme EA, Leech L, Duester G: Fuel management. In: Keep on running: the science of training and performance. pp. 95-112. West Sussex, UK: John Wiley & Sons, Ltd., 1994 pp. 95-11.
  • 15
    • 16644390946 scopus 로고    scopus 로고
    • Energy system contribution to 100-m and 200-m track running events
    • Duffield R., Dawson B., and Goodman C. Energy system contribution to 100-m and 200-m track running events. J Sci Med Sport 7 (2004) 302-313
    • (2004) J Sci Med Sport , vol.7 , pp. 302-313
    • Duffield, R.1    Dawson, B.2    Goodman, C.3
  • 16
    • 0038823577 scopus 로고    scopus 로고
    • 31P-MRS characterization of sprint and endurance trained athletes
    • Johansen L., and Quistorff B. 31P-MRS characterization of sprint and endurance trained athletes. Int J Sports Med 24 (2003) 183-189
    • (2003) Int J Sports Med , vol.24 , pp. 183-189
    • Johansen, L.1    Quistorff, B.2
  • 18
    • 49749165001 scopus 로고
    • The phosphorylase b to a converting enzyme of rabbit skeletal muscle
    • Krebs E.G., and Fischer E.H. The phosphorylase b to a converting enzyme of rabbit skeletal muscle. Biochim Biophys Acta 20 (1956) 150-157
    • (1956) Biochim Biophys Acta , vol.20 , pp. 150-157
    • Krebs, E.G.1    Fischer, E.H.2
  • 19
    • 0034095332 scopus 로고    scopus 로고
    • Myocardial substrate metabolism influences left ventricular energetics in vivo
    • Korvald C., Elvenes O.P., and Myrmel T. Myocardial substrate metabolism influences left ventricular energetics in vivo. Am J Physiol Heart Circ Physiol 278 (2000) H1345-H1351
    • (2000) Am J Physiol Heart Circ Physiol , vol.278
    • Korvald, C.1    Elvenes, O.P.2    Myrmel, T.3
  • 20
    • 0022895234 scopus 로고
    • Marathon fatigue: the role of plasma fatty acids, muscle glycogen and blood glucose
    • Callow M., Morton A., and Guppy M. Marathon fatigue: the role of plasma fatty acids, muscle glycogen and blood glucose. Eur J Appl Physiol Occup Physiol 55 (1986) 654-661
    • (1986) Eur J Appl Physiol Occup Physiol , vol.55 , pp. 654-661
    • Callow, M.1    Morton, A.2    Guppy, M.3
  • 21
    • 0022362465 scopus 로고
    • Applied physiology of marathon running
    • Sjodin B., and Svedenhag J. Applied physiology of marathon running. Sports Med 2 (1985) 83-99
    • (1985) Sports Med , vol.2 , pp. 83-99
    • Sjodin, B.1    Svedenhag, J.2
  • 22
    • 0024450189 scopus 로고
    • Effect of training and 15-, 25-, and 42-km contests on the skeletal muscle content of adenine and guanine nucleotides, creatine phosphate, and glycogen
    • van der Vusse G.J., Janssen G.M., Coumans W.A., et al. Effect of training and 15-, 25-, and 42-km contests on the skeletal muscle content of adenine and guanine nucleotides, creatine phosphate, and glycogen. Int J Sports Med 3 10 Suppl (1989) S146-S152
    • (1989) Int J Sports Med , vol.3 , Issue.10 SUPPL
    • van der Vusse, G.J.1    Janssen, G.M.2    Coumans, W.A.3
  • 23
    • 0020553120 scopus 로고
    • Effect of a 42.2-km footrace and subsequent rest or exercise on muscle glycogen and enzymes
    • Sherman W.M., Costill D.L., Fink W.J., et al. Effect of a 42.2-km footrace and subsequent rest or exercise on muscle glycogen and enzymes. J Appl Physiol 55 (1983) 1219-1224
    • (1983) J Appl Physiol , vol.55 , pp. 1219-1224
    • Sherman, W.M.1    Costill, D.L.2    Fink, W.J.3
  • 24
    • 0345376265 scopus 로고    scopus 로고
    • Effect of exercise intensity, duration and mode on post-exercise oxygen consumption
    • Borsheim E., and Bahr R. Effect of exercise intensity, duration and mode on post-exercise oxygen consumption. Sports Med 33 (2003) 1037-1060
    • (2003) Sports Med , vol.33 , pp. 1037-1060
    • Borsheim, E.1    Bahr, R.2
  • 25
    • 0022475891 scopus 로고
    • Magnitude and duration of excess postexercise oxygen consumption in healthy young subjects
    • Maehlum S., Grandmontagne M., Newsholme E.A., et al. Magnitude and duration of excess postexercise oxygen consumption in healthy young subjects. Metabolism 35 (1986) 425-429
    • (1986) Metabolism , vol.35 , pp. 425-429
    • Maehlum, S.1    Grandmontagne, M.2    Newsholme, E.A.3
  • 26
    • 0028287972 scopus 로고
    • Exercise induces rapid increases in GLUT4 expression, glucose transport capacity, and insulin-stimulated glycogen storage in muscle
    • Ren J.M., Semenkovich C.F., Gulve E.A., et al. Exercise induces rapid increases in GLUT4 expression, glucose transport capacity, and insulin-stimulated glycogen storage in muscle. J Biol Chem 269 (1994) 14396-14401
    • (1994) J Biol Chem , vol.269 , pp. 14396-14401
    • Ren, J.M.1    Semenkovich, C.F.2    Gulve, E.A.3
  • 27
    • 0031877032 scopus 로고    scopus 로고
    • Glycogen supercompensation masks the effect of a training-induced increase in GLUT-4 on muscle glucose transport
    • Host H.H., Hansen P.A., Nolte L.A., et al. Glycogen supercompensation masks the effect of a training-induced increase in GLUT-4 on muscle glucose transport. J Appl Physiol 85 (1998) 133-138
    • (1998) J Appl Physiol , vol.85 , pp. 133-138
    • Host, H.H.1    Hansen, P.A.2    Nolte, L.A.3
  • 28
    • 0141839096 scopus 로고    scopus 로고
    • Prevention of glycogen supercompensation prolongs the increase in muscle GLUT4 after exercise
    • Garcia-Roves P.M., Han D.H., Song Z., et al. Prevention of glycogen supercompensation prolongs the increase in muscle GLUT4 after exercise. Am J Physiol Endocrinol Metab 285 (2003) E729-E736
    • (2003) Am J Physiol Endocrinol Metab , vol.285
    • Garcia-Roves, P.M.1    Han, D.H.2    Song, Z.3
  • 29
    • 0037095899 scopus 로고    scopus 로고
    • Influence of pre-exercise muscle glycogen content on exercise-induced transcriptional regulation of metabolic genes
    • Pilegaard H., Keller C., Steensberg A., et al. Influence of pre-exercise muscle glycogen content on exercise-induced transcriptional regulation of metabolic genes. J Physiol 541 (2002) 261-271
    • (2002) J Physiol , vol.541 , pp. 261-271
    • Pilegaard, H.1    Keller, C.2    Steensberg, A.3
  • 30
    • 22144434964 scopus 로고    scopus 로고
    • Transcriptional coactivator PGC-1 alpha controls the energy state and contractile function of cardiac muscle
    • Arany Z., He H., Lin J., et al. Transcriptional coactivator PGC-1 alpha controls the energy state and contractile function of cardiac muscle. Cell Metab 1 (2005) 259-271
    • (2005) Cell Metab , vol.1 , pp. 259-271
    • Arany, Z.1    He, H.2    Lin, J.3
  • 31
    • 22744446447 scopus 로고    scopus 로고
    • Substrate availability and transcriptional regulation of metabolic genes in human skeletal muscle during recovery from exercise
    • Pilegaard H., Osada T., Andersen L.T., et al. Substrate availability and transcriptional regulation of metabolic genes in human skeletal muscle during recovery from exercise. Metabolism 54 (2005) 1048-1055
    • (2005) Metabolism , vol.54 , pp. 1048-1055
    • Pilegaard, H.1    Osada, T.2    Andersen, L.T.3
  • 32
    • 0014695989 scopus 로고
    • Metabolic fuels during and after severe exercise in athletes and non-athletes
    • Johnson R., Walton J., Krebs H., et al. Metabolic fuels during and after severe exercise in athletes and non-athletes. Lancet 2 (1969) 452-455
    • (1969) Lancet , vol.2 , pp. 452-455
    • Johnson, R.1    Walton, J.2    Krebs, H.3
  • 33
    • 0032508696 scopus 로고    scopus 로고
    • Fatty acids activate transcription of the muscle carnitine palmitoyltransferase I gene in cardiac myocytes via the peroxisome proliferator-activated receptor alpha
    • Brandt J.M., Djouadi F., and Kelly D.P. Fatty acids activate transcription of the muscle carnitine palmitoyltransferase I gene in cardiac myocytes via the peroxisome proliferator-activated receptor alpha. J Biol Chem 273 (1998) 23786-23792
    • (1998) J Biol Chem , vol.273 , pp. 23786-23792
    • Brandt, J.M.1    Djouadi, F.2    Kelly, D.P.3
  • 34
    • 34248589911 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma coactivator-1 (PGC-1) regulatory cascade in cardiac physiology and disease
    • Finck B.N., and Kelly D.P. Peroxisome proliferator-activated receptor gamma coactivator-1 (PGC-1) regulatory cascade in cardiac physiology and disease. Circulation 115 (2007) 2540-2548
    • (2007) Circulation , vol.115 , pp. 2540-2548
    • Finck, B.N.1    Kelly, D.P.2
  • 35
    • 33750881942 scopus 로고    scopus 로고
    • Role of glycogen synthase kinase-3 in insulin resistance and type 2 diabetes
    • Henriksen E.J., and Dokken B.B. Role of glycogen synthase kinase-3 in insulin resistance and type 2 diabetes. Curr Drug Targets 7 (2006) 1435-1441
    • (2006) Curr Drug Targets , vol.7 , pp. 1435-1441
    • Henriksen, E.J.1    Dokken, B.B.2
  • 36
    • 33745870108 scopus 로고    scopus 로고
    • Chronic selective glycogen synthase kinase-3 inhibition enhances glucose disposal and muscle insulin action in prediabetic obese Zucker rats
    • Dokken B.B., and Henriksen E.J. Chronic selective glycogen synthase kinase-3 inhibition enhances glucose disposal and muscle insulin action in prediabetic obese Zucker rats. Am J Physiol Endocrinol Metab 291 (2006) E207-E213
    • (2006) Am J Physiol Endocrinol Metab , vol.291
    • Dokken, B.B.1    Henriksen, E.J.2
  • 37
    • 0037405647 scopus 로고    scopus 로고
    • Modulation of muscle insulin resistance by selective inhibition of GSK-3 in Zucker diabetic fatty rats
    • Henriksen E.J., Kinnick T.R., Teachey M.K., et al. Modulation of muscle insulin resistance by selective inhibition of GSK-3 in Zucker diabetic fatty rats. Am J Physiol Endocrinol Metab 284 (2003) E892-E900
    • (2003) Am J Physiol Endocrinol Metab , vol.284
    • Henriksen, E.J.1    Kinnick, T.R.2    Teachey, M.K.3
  • 38
    • 46849104558 scopus 로고    scopus 로고
    • Carnitine palmitoyltransferase I (Cpt I) overexpression protects L6e9 muscle cells from fatty acid-induced insulin resistance
    • Sebastian D., Herrero L., Serra D., et al. Carnitine palmitoyltransferase I (Cpt I) overexpression protects L6e9 muscle cells from fatty acid-induced insulin resistance. Am J Physiol Endocrinol Metab (2006)
    • (2006) Am J Physiol Endocrinol Metab
    • Sebastian, D.1    Herrero, L.2    Serra, D.3
  • 39
    • 3042551249 scopus 로고    scopus 로고
    • Increased beta-oxidation in muscle cells enhances insulin-stimulated glucose metabolism and protects against fatty acid-induced insulin resistance despite intramyocellular lipid accumulation
    • Perdomo G., Commerford S.R., Richard A.M., et al. Increased beta-oxidation in muscle cells enhances insulin-stimulated glucose metabolism and protects against fatty acid-induced insulin resistance despite intramyocellular lipid accumulation. J Biol Chem 279 (2004) 27177-27186
    • (2004) J Biol Chem , vol.279 , pp. 27177-27186
    • Perdomo, G.1    Commerford, S.R.2    Richard, A.M.3
  • 40
    • 33751195101 scopus 로고    scopus 로고
    • AMP-activated protein kinase and the regulation of glucose transport
    • Fujii N., Jessen N., and Goodyear L.J. AMP-activated protein kinase and the regulation of glucose transport. Am J Physiol Endocrinol Metab 291 (2006) E867-E877
    • (2006) Am J Physiol Endocrinol Metab , vol.291
    • Fujii, N.1    Jessen, N.2    Goodyear, L.J.3
  • 41
    • 10744228615 scopus 로고    scopus 로고
    • Insulin signalling and resistance in patients with chronic heart failure
    • Kemppainen J., Tsuchida H., Stolen K., et al. Insulin signalling and resistance in patients with chronic heart failure. J Physiol 550 (2003) 305-315
    • (2003) J Physiol , vol.550 , pp. 305-315
    • Kemppainen, J.1    Tsuchida, H.2    Stolen, K.3
  • 42
    • 0029910598 scopus 로고    scopus 로고
    • Cardiac and skeletal muscle insulin resistance in patients with coronary heart disease. A study with positron emission tomography
    • Paternostro G., Camici P.G., Lammertsma A.A., et al. Cardiac and skeletal muscle insulin resistance in patients with coronary heart disease. A study with positron emission tomography. J Clin Invest 98 (1996) 2094-2099
    • (1996) J Clin Invest , vol.98 , pp. 2094-2099
    • Paternostro, G.1    Camici, P.G.2    Lammertsma, A.A.3
  • 43
    • 33845201058 scopus 로고    scopus 로고
    • Myocardial glucose transport and utilization in patients with type 2 diabetes mellitus, left ventricular dysfunction, and coronary artery disease
    • Dutka D.P., Pitt M., Pagano D., et al. Myocardial glucose transport and utilization in patients with type 2 diabetes mellitus, left ventricular dysfunction, and coronary artery disease. J Am Coll Cardiol 48 (2006) 2225-2231
    • (2006) J Am Coll Cardiol , vol.48 , pp. 2225-2231
    • Dutka, D.P.1    Pitt, M.2    Pagano, D.3
  • 44
    • 0036788287 scopus 로고    scopus 로고
    • Independent association of type 2 diabetes and coronary artery disease with myocardial insulin resistance
    • Iozzo P., Chareonthaitawee P., Dutka D., et al. Independent association of type 2 diabetes and coronary artery disease with myocardial insulin resistance. Diabetes 51 (2002) 3020-3024
    • (2002) Diabetes , vol.51 , pp. 3020-3024
    • Iozzo, P.1    Chareonthaitawee, P.2    Dutka, D.3
  • 45
    • 0019362976 scopus 로고
    • Energy cycles in health and disease
    • Racker E. Energy cycles in health and disease. Curr Top Cell Regul 18 (1981) 361-375
    • (1981) Curr Top Cell Regul , vol.18 , pp. 361-375
    • Racker, E.1
  • 46
    • 0032491520 scopus 로고    scopus 로고
    • Regulation of energy metabolism of the heart during acute increase in heart work
    • Goodwin G.W., Taylor C.S., and Taegtmeyer H. Regulation of energy metabolism of the heart during acute increase in heart work. J Biol Chem 273 (1998) 29530-29539
    • (1998) J Biol Chem , vol.273 , pp. 29530-29539
    • Goodwin, G.W.1    Taylor, C.S.2    Taegtmeyer, H.3
  • 47
    • 3142543633 scopus 로고    scopus 로고
    • Glycogen in the heart-an expanded view
    • Taegtmeyer H. Glycogen in the heart-an expanded view. J Mol Cell Cardiol 37 (2004) 7-10
    • (2004) J Mol Cell Cardiol , vol.37 , pp. 7-10
    • Taegtmeyer, H.1
  • 48
    • 0033711215 scopus 로고    scopus 로고
    • Improved energy homeostasis of the heart in the metabolic state of exercise
    • Goodwin G.W., and Taegtmeyer H. Improved energy homeostasis of the heart in the metabolic state of exercise. Am J Physiol Heart Circ Physiol 279 (2000) H1490-H1501
    • (2000) Am J Physiol Heart Circ Physiol , vol.279
    • Goodwin, G.W.1    Taegtmeyer, H.2
  • 49
    • 0036302960 scopus 로고    scopus 로고
    • Inhibition of glycogen synthase kinase 3 improves insulin action and glucose metabolism in human skeletal muscle
    • Nikoulina S.E., Ciaraldi T.P., Mudaliar S., et al. Inhibition of glycogen synthase kinase 3 improves insulin action and glucose metabolism in human skeletal muscle. Diabetes 51 (2002) 2190-2198
    • (2002) Diabetes , vol.51 , pp. 2190-2198
    • Nikoulina, S.E.1    Ciaraldi, T.P.2    Mudaliar, S.3
  • 50
    • 2642541582 scopus 로고    scopus 로고
    • Exercise regulates Akt and glycogen synthase kinase-3 activities in human skeletal muscle
    • Sakamoto K., Arnolds D.E., Ekberg I., et al. Exercise regulates Akt and glycogen synthase kinase-3 activities in human skeletal muscle. Biochem Biophys Res Commun 319 (2004) 419-425
    • (2004) Biochem Biophys Res Commun , vol.319 , pp. 419-425
    • Sakamoto, K.1    Arnolds, D.E.2    Ekberg, I.3
  • 51
    • 0142052855 scopus 로고    scopus 로고
    • Akt signaling in skeletal muscle: regulation by exercise and passive stretch
    • Sakamoto K., Aschenbach W.G., Hirshman M.F., et al. Akt signaling in skeletal muscle: regulation by exercise and passive stretch. Am J Physiol Endocrinol Metab 285 (2003) E1081-E1088
    • (2003) Am J Physiol Endocrinol Metab , vol.285
    • Sakamoto, K.1    Aschenbach, W.G.2    Hirshman, M.F.3
  • 52
    • 0037125980 scopus 로고    scopus 로고
    • Akt induces enhanced myocardial contractility and cell size in vivo in transgenic mice
    • Condorelli G., Drusco A., Stassi G., et al. Akt induces enhanced myocardial contractility and cell size in vivo in transgenic mice. Proc Natl Acad Sci U S A 99 (2002) 12333-12338
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 12333-12338
    • Condorelli, G.1    Drusco, A.2    Stassi, G.3
  • 53
    • 0033851801 scopus 로고    scopus 로고
    • Effect of endurance training on lipid metabolism in women: a potential role for PPARalpha in the metabolic response to training
    • Horowitz J.F., Leone T.C., Feng W., et al. Effect of endurance training on lipid metabolism in women: a potential role for PPARalpha in the metabolic response to training. Am J Physiol Endocrinol Metab 279 (2000) E348-E355
    • (2000) Am J Physiol Endocrinol Metab , vol.279
    • Horowitz, J.F.1    Leone, T.C.2    Feng, W.3
  • 54
    • 0036903174 scopus 로고    scopus 로고
    • Adaptations of skeletal muscle to exercise: rapid increase in the transcriptional coactivator PGC-1
    • Baar K., Wende A.R., Jones T.E., et al. Adaptations of skeletal muscle to exercise: rapid increase in the transcriptional coactivator PGC-1. FASEB J 16 (2002) 1879-1886
    • (2002) FASEB J , vol.16 , pp. 1879-1886
    • Baar, K.1    Wende, A.R.2    Jones, T.E.3
  • 55
    • 0037322888 scopus 로고    scopus 로고
    • Exercise induces transient transcriptional activation of the PGC-1alpha gene in human skeletal muscle
    • Pilegaard H., Saltin B., and Neufer P.D. Exercise induces transient transcriptional activation of the PGC-1alpha gene in human skeletal muscle. J Physiol 546 (2003) 851-858
    • (2003) J Physiol , vol.546 , pp. 851-858
    • Pilegaard, H.1    Saltin, B.2    Neufer, P.D.3
  • 56
    • 0033803048 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma coactivator-1 promotes cardiac mitochondrial biogenesis
    • Lehman J.J., Barger P.M., Kovacs A., et al. Peroxisome proliferator-activated receptor gamma coactivator-1 promotes cardiac mitochondrial biogenesis. J Clin Invest 106 (2000) 847-856
    • (2000) J Clin Invest , vol.106 , pp. 847-856
    • Lehman, J.J.1    Barger, P.M.2    Kovacs, A.3
  • 57
    • 0018991609 scopus 로고
    • Myocardial oxygen and carbohydrate consumption in fetal lambs in utero and in adult sheep
    • Fisher D.J., Heymann M.A., and Rudolph A.M. Myocardial oxygen and carbohydrate consumption in fetal lambs in utero and in adult sheep. Am J Physiol 238 (1980) H399-H405
    • (1980) Am J Physiol , vol.238
    • Fisher, D.J.1    Heymann, M.A.2    Rudolph, A.M.3
  • 58
    • 0034702930 scopus 로고    scopus 로고
    • Perinatal changes in myocardial metabolism in lambs
    • Bartelds B., Knoester H., Smid G.B., et al. Perinatal changes in myocardial metabolism in lambs. Circulation 102 (2000) 926-931
    • (2000) Circulation , vol.102 , pp. 926-931
    • Bartelds, B.1    Knoester, H.2    Smid, G.B.3
  • 60
    • 0020161018 scopus 로고
    • Ultrastructural and enzymatic development of fetal guinea pig heart
    • Rolph T., Jones C., and Parry D. Ultrastructural and enzymatic development of fetal guinea pig heart. Am J Physiol 243 (1982) H87-H93
    • (1982) Am J Physiol , vol.243
    • Rolph, T.1    Jones, C.2    Parry, D.3
  • 61
    • 0019515849 scopus 로고
    • Myocardial consumption of oxygen and carbohydrates in newborn sheep
    • Fisher D., Heymann M., and Rudolph A. Myocardial consumption of oxygen and carbohydrates in newborn sheep. Pediatr Res 15 (1981) 843-846
    • (1981) Pediatr Res , vol.15 , pp. 843-846
    • Fisher, D.1    Heymann, M.2    Rudolph, A.3
  • 62
    • 3543028031 scopus 로고    scopus 로고
    • Abnormal cardiac development in the absence of heart glycogen
    • Pederson B.A., Chen H., Schroeder J.M., et al. Abnormal cardiac development in the absence of heart glycogen. Mol Cell Biol 24 (2004) 7179-7187
    • (2004) Mol Cell Biol , vol.24 , pp. 7179-7187
    • Pederson, B.A.1    Chen, H.2    Schroeder, J.M.3
  • 63
    • 0026322397 scopus 로고
    • Glycolysis is predominant source of ATP production immediately after birth
    • Lopaschuk G.D., Spafford M.A., and Marsh D.R. Glycolysis is predominant source of ATP production immediately after birth. Am J Physiol 261 (1991) H1698-H1705
    • (1991) Am J Physiol , vol.261
    • Lopaschuk, G.D.1    Spafford, M.A.2    Marsh, D.R.3
  • 64
    • 0036118922 scopus 로고    scopus 로고
    • Transcriptional activation of energy metabolic switches in the developing and hypertrophied heart
    • Lehman J.J., and Kelly D.P. Transcriptional activation of energy metabolic switches in the developing and hypertrophied heart. Clin Exp Pharmacol Physiol 29 (2002) 339-345
    • (2002) Clin Exp Pharmacol Physiol , vol.29 , pp. 339-345
    • Lehman, J.J.1    Kelly, D.P.2
  • 65
    • 0037232725 scopus 로고    scopus 로고
    • Relative importance of malonyl CoA and carnitine in maturation of fatty acid oxidation in newborn rabbit heart
    • Onay-Besikci A., Campbell F.M., Hopkins T.A., et al. Relative importance of malonyl CoA and carnitine in maturation of fatty acid oxidation in newborn rabbit heart. Am J Physiol Heart Circ Physiol 284 (2003) H283-H289
    • (2003) Am J Physiol Heart Circ Physiol , vol.284
    • Onay-Besikci, A.1    Campbell, F.M.2    Hopkins, T.A.3
  • 66
    • 0030923761 scopus 로고    scopus 로고
    • A role for Sp and nuclear receptor transcription factors in a cardiac hypertrophic growth program
    • Sack M.N., Disch D.L., Rockman H.A., et al. A role for Sp and nuclear receptor transcription factors in a cardiac hypertrophic growth program. Proc Natl Acad Sci U S A 94 (1997) 6438-6443
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 6438-6443
    • Sack, M.N.1    Disch, D.L.2    Rockman, H.A.3
  • 67
    • 0031761451 scopus 로고    scopus 로고
    • Unloaded heart in vivo replicates fetal gene expression of cardiac hypertrophy
    • Depre C., Shipley G.L., Chen W., et al. Unloaded heart in vivo replicates fetal gene expression of cardiac hypertrophy. Nat Med 4 (1998) 1269-1275
    • (1998) Nat Med , vol.4 , pp. 1269-1275
    • Depre, C.1    Shipley, G.L.2    Chen, W.3
  • 68
    • 0035846554 scopus 로고    scopus 로고
    • Metabolic gene expression in fetal and failing human heart
    • Razeghi P., Young M.E., Alcorn J.L., et al. Metabolic gene expression in fetal and failing human heart. Circulation 104 (2001) 2923-2931
    • (2001) Circulation , vol.104 , pp. 2923-2931
    • Razeghi, P.1    Young, M.E.2    Alcorn, J.L.3
  • 69
    • 0023885409 scopus 로고
    • Effects of moderate hypertension on cardiac function and metabolism in the rabbit
    • Taegtmeyer H., and Overturf M.L. Effects of moderate hypertension on cardiac function and metabolism in the rabbit. Hypertension 11 (1988) 416-426
    • (1988) Hypertension , vol.11 , pp. 416-426
    • Taegtmeyer, H.1    Overturf, M.L.2
  • 70
    • 0034467428 scopus 로고    scopus 로고
    • PPAR signaling in the control of cardiac energy metabolism
    • Barger P.M., and Kelly D.P. PPAR signaling in the control of cardiac energy metabolism. Trends Cardiovasc Med 10 (2000) 238-245
    • (2000) Trends Cardiovasc Med , vol.10 , pp. 238-245
    • Barger, P.M.1    Kelly, D.P.2
  • 71
    • 0036773047 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor alpha (PPARalpha) signaling in the gene regulatory control of energy metabolism in the normal and diseased heart
    • Finck B.N., and Kelly D.P. Peroxisome proliferator-activated receptor alpha (PPARalpha) signaling in the gene regulatory control of energy metabolism in the normal and diseased heart. J Mol Cell Cardiol 34 (2002) 1249-1257
    • (2002) J Mol Cell Cardiol , vol.34 , pp. 1249-1257
    • Finck, B.N.1    Kelly, D.P.2
  • 72
    • 33644660537 scopus 로고    scopus 로고
    • PGC-1 coactivators: inducible regulators of energy metabolism in health and disease
    • Finck B.N., and Kelly D.P. PGC-1 coactivators: inducible regulators of energy metabolism in health and disease. J Clin Invest 116 (2006) 615-622
    • (2006) J Clin Invest , vol.116 , pp. 615-622
    • Finck, B.N.1    Kelly, D.P.2
  • 73
    • 0033933236 scopus 로고    scopus 로고
    • Deactivation of peroxisome proliferator-activated receptor-alpha during cardiac hypertrophic growth
    • Barger P.M., Brandt J.M., Leone T.C., et al. Deactivation of peroxisome proliferator-activated receptor-alpha during cardiac hypertrophic growth. J Clin Invest 105 (2000) 1723-1730
    • (2000) J Clin Invest , vol.105 , pp. 1723-1730
    • Barger, P.M.1    Brandt, J.M.2    Leone, T.C.3
  • 74
    • 0029939625 scopus 로고    scopus 로고
    • Transcriptional control of a nuclear gene encoding a mitochondrial fatty acid oxidation enzyme in transgenic mice: role for nuclear receptors in cardiac and brown adipose expression
    • Disch D.L., Rader T.A., Cresci S., et al. Transcriptional control of a nuclear gene encoding a mitochondrial fatty acid oxidation enzyme in transgenic mice: role for nuclear receptors in cardiac and brown adipose expression. Mol Cell Biol 16 (1996) 4043-4051
    • (1996) Mol Cell Biol , vol.16 , pp. 4043-4051
    • Disch, D.L.1    Rader, T.A.2    Cresci, S.3
  • 75
    • 3042718647 scopus 로고    scopus 로고
    • Regulation of cell size and contractile function by AKT in cardiomyocytes
    • Latronico M.V., Costinean S., Lavitrano M.L., et al. Regulation of cell size and contractile function by AKT in cardiomyocytes. Ann N Y Acad Sci 1015 (2004) 250-260
    • (2004) Ann N Y Acad Sci , vol.1015 , pp. 250-260
    • Latronico, M.V.1    Costinean, S.2    Lavitrano, M.L.3
  • 76
    • 0036172127 scopus 로고    scopus 로고
    • Fas receptor signaling inhibits glycogen synthase kinase 3 beta and induces cardiac hypertrophy following pressure overload
    • Badorff C., Ruetten H., Mueller S., et al. Fas receptor signaling inhibits glycogen synthase kinase 3 beta and induces cardiac hypertrophy following pressure overload. J Clin Invest 109 (2002) 373-381
    • (2002) J Clin Invest , vol.109 , pp. 373-381
    • Badorff, C.1    Ruetten, H.2    Mueller, S.3
  • 77
    • 0034597147 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3beta is a negative regulator of cardiomyocyte hypertrophy
    • Haq S., Choukroun G., Kang Z.B., et al. Glycogen synthase kinase-3beta is a negative regulator of cardiomyocyte hypertrophy. J Cell Biol 151 (2000) 117-130
    • (2000) J Cell Biol , vol.151 , pp. 117-130
    • Haq, S.1    Choukroun, G.2    Kang, Z.B.3
  • 78
    • 2442714120 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3beta regulates growth, calcium homeostasis, and diastolic function in the heart
    • Michael A., Haq S., Chen X., et al. Glycogen synthase kinase-3beta regulates growth, calcium homeostasis, and diastolic function in the heart. J Biol Chem 279 (2004) 21383-21393
    • (2004) J Biol Chem , vol.279 , pp. 21383-21393
    • Michael, A.1    Haq, S.2    Chen, X.3
  • 79
    • 0035902451 scopus 로고    scopus 로고
    • Akt activation preserves cardiac function and prevents injury after transient cardiac ischemia in vivo
    • Matsui T., Tao J., del Monte F., et al. Akt activation preserves cardiac function and prevents injury after transient cardiac ischemia in vivo. Circulation 104 (2001) 330-335
    • (2001) Circulation , vol.104 , pp. 330-335
    • Matsui, T.1    Tao, J.2    del Monte, F.3
  • 80
    • 0030984321 scopus 로고    scopus 로고
    • New insights into the role and mechanism of glycogen synthase activation by insulin
    • Lawrence J.C., and Roach P.J. New insights into the role and mechanism of glycogen synthase activation by insulin. Diabetes 46 (1997) 541-547
    • (1997) Diabetes , vol.46 , pp. 541-547
    • Lawrence, J.C.1    Roach, P.J.2
  • 81
    • 26844561663 scopus 로고    scopus 로고
    • Decreased contractile and metabolic reserve in peroxisome proliferator-activated receptor-alpha-null hearts can be rescued by increasing glucose transport and utilization
    • Luptak I., Balschi J.A., Xing Y., et al. Decreased contractile and metabolic reserve in peroxisome proliferator-activated receptor-alpha-null hearts can be rescued by increasing glucose transport and utilization. Circulation 112 (2005) 2339-2346
    • (2005) Circulation , vol.112 , pp. 2339-2346
    • Luptak, I.1    Balschi, J.A.2    Xing, Y.3
  • 82
    • 0037151104 scopus 로고    scopus 로고
    • Phenotypic spectrum caused by transgenic overexpression of activated Akt in the heart
    • Matsui T., Li L., Wu J., et al. Phenotypic spectrum caused by transgenic overexpression of activated Akt in the heart. J Biol Chem 277 (2002) 22896-22901
    • (2002) J Biol Chem , vol.277 , pp. 22896-22901
    • Matsui, T.1    Li, L.2    Wu, J.3
  • 83
    • 0021916285 scopus 로고
    • The economy of isometric force development, myosin isoenzyme pattern and myofibrillar ATPase activity in normal and hypothyroid rat myocardium
    • Holubarsch C., Goulette R.P., Litten R.Z., et al. The economy of isometric force development, myosin isoenzyme pattern and myofibrillar ATPase activity in normal and hypothyroid rat myocardium. Circ Res 56 (1985) 78-86
    • (1985) Circ Res , vol.56 , pp. 78-86
    • Holubarsch, C.1    Goulette, R.P.2    Litten, R.Z.3
  • 84
    • 0037117651 scopus 로고    scopus 로고
    • Adaptation and maladaptation of the heart in diabetes: part II: potential mechanisms
    • Young M.E., McNulty P., and Taegtmeyer H. Adaptation and maladaptation of the heart in diabetes: part II: potential mechanisms. Circulation 105 (2002) 1861-1870
    • (2002) Circulation , vol.105 , pp. 1861-1870
    • Young, M.E.1    McNulty, P.2    Taegtmeyer, H.3
  • 85
    • 41749100066 scopus 로고    scopus 로고
    • Proposed regulation of gene expression by glucose in rodent heart
    • Young M.E., Yan J., Razeghi P., et al. Proposed regulation of gene expression by glucose in rodent heart. Gene Reg Sys Biol 1 (2007) 251-262
    • (2007) Gene Reg Sys Biol , vol.1 , pp. 251-262
    • Young, M.E.1    Yan, J.2    Razeghi, P.3
  • 86
    • 0035976932 scopus 로고    scopus 로고
    • Reactivation of peroxisome proliferator-activated receptor alpha is associated with contractile dysfunction in hypertrophied rat heart
    • Young M.E., Laws F.A., Goodwin G.W., et al. Reactivation of peroxisome proliferator-activated receptor alpha is associated with contractile dysfunction in hypertrophied rat heart. J Biol Chem 276 (2001) 44390-44395
    • (2001) J Biol Chem , vol.276 , pp. 44390-44395
    • Young, M.E.1    Laws, F.A.2    Goodwin, G.W.3
  • 87
    • 0031104921 scopus 로고    scopus 로고
    • Regression of cardiac hypertrophy normalizes glucose metabolism and left ventricular function during reperfusion
    • Wambolt R.B., Henning S.L., English D.R., et al. Regression of cardiac hypertrophy normalizes glucose metabolism and left ventricular function during reperfusion. J Mol Cell Cardiol 29 (1997) 939-948
    • (1997) J Mol Cell Cardiol , vol.29 , pp. 939-948
    • Wambolt, R.B.1    Henning, S.L.2    English, D.R.3
  • 88
    • 19044396142 scopus 로고    scopus 로고
    • Downregulation of metabolic gene expression in failing human heart before and after mechanical unloading
    • Razeghi P., Young M.E., Ying J., et al. Downregulation of metabolic gene expression in failing human heart before and after mechanical unloading. Cardiology 97 (2002) 203-209
    • (2002) Cardiology , vol.97 , pp. 203-209
    • Razeghi, P.1    Young, M.E.2    Ying, J.3
  • 89
    • 31944439065 scopus 로고    scopus 로고
    • Atrophic remodeling of the transplanted rat heart
    • Sharma S., Ying J., Razeghi P., et al. Atrophic remodeling of the transplanted rat heart. Cardiology 105 (2006) 128-136
    • (2006) Cardiology , vol.105 , pp. 128-136
    • Sharma, S.1    Ying, J.2    Razeghi, P.3
  • 90
    • 0032781007 scopus 로고    scopus 로고
    • Regulation of cardiovascular development and physiology by hypoxia-inducible factor 1
    • Semenza G.L., Agani F., Iyer N., et al. Regulation of cardiovascular development and physiology by hypoxia-inducible factor 1. Ann N Y Acad Sci 30 (1999) 262-268
    • (1999) Ann N Y Acad Sci , vol.30 , pp. 262-268
    • Semenza, G.L.1    Agani, F.2    Iyer, N.3
  • 91
    • 0035920140 scopus 로고    scopus 로고
    • Hypoxia inhibits the PPAR{alpha}/RXR gene regulatory pathway in cardiac myocytes. A mechanism for O{sub2}-dependent modulation of mitochondrial fatty acid oxidation
    • Huss J.M., Levy F.H., and Kelly D.P. Hypoxia inhibits the PPAR{alpha}/RXR gene regulatory pathway in cardiac myocytes. A mechanism for O{sub2}-dependent modulation of mitochondrial fatty acid oxidation. J Biol Chem 276 (2001) 27605-27612
    • (2001) J Biol Chem , vol.276 , pp. 27605-27612
    • Huss, J.M.1    Levy, F.H.2    Kelly, D.P.3
  • 92
    • 0035860177 scopus 로고    scopus 로고
    • Hypoxia in vivo decreases peroxisome proliferator-activated receptor alpha-regulated gene expression in rat heart
    • Razeghi P., Young M.E., Abbasi S., et al. Hypoxia in vivo decreases peroxisome proliferator-activated receptor alpha-regulated gene expression in rat heart. Biochem Biophys Res Commun 287 (2001) 5-10
    • (2001) Biochem Biophys Res Commun , vol.287 , pp. 5-10
    • Razeghi, P.1    Young, M.E.2    Abbasi, S.3
  • 93
    • 0345505276 scopus 로고    scopus 로고
    • Hypoxia-induced switches of myosin heavy chain iso-gene expression in rat heart
    • Razeghi P., Essop M.F., Huss J.M., et al. Hypoxia-induced switches of myosin heavy chain iso-gene expression in rat heart. Biochem Biophys Res Commun 303 (2003) 1024-1027
    • (2003) Biochem Biophys Res Commun , vol.303 , pp. 1024-1027
    • Razeghi, P.1    Essop, M.F.2    Huss, J.M.3
  • 94
    • 0037040856 scopus 로고    scopus 로고
    • Phosphorylation of glycogen synthase kinase-3beta during preconditioning through a phosphatidylinositol-3-kinase-dependent pathway is cardioprotective
    • Tong H., Imahashi K., Steenbergen C., et al. Phosphorylation of glycogen synthase kinase-3beta during preconditioning through a phosphatidylinositol-3-kinase-dependent pathway is cardioprotective. Circ Res 90 (2002) 377-379
    • (2002) Circ Res , vol.90 , pp. 377-379
    • Tong, H.1    Imahashi, K.2    Steenbergen, C.3
  • 95
    • 33746837190 scopus 로고    scopus 로고
    • Erythropoietin affords additional cardioprotection to preconditioned hearts by enhanced phosphorylation of glycogen synthase kinase-3 beta
    • Nishihara M., Miura T., Miki T., et al. Erythropoietin affords additional cardioprotection to preconditioned hearts by enhanced phosphorylation of glycogen synthase kinase-3 beta. Am J Physiol Heart Circ Physiol 291 (2006) H748-H755
    • (2006) Am J Physiol Heart Circ Physiol , vol.291
    • Nishihara, M.1    Miura, T.2    Miki, T.3
  • 96
    • 0037704228 scopus 로고    scopus 로고
    • Persistent stunning induces myocardial hibernation and protection: flow/function and metabolic mechanisms
    • Kim S.J., Peppas A., Hong S.K., et al. Persistent stunning induces myocardial hibernation and protection: flow/function and metabolic mechanisms. Circ Res 92 (2003) 1233-1239
    • (2003) Circ Res , vol.92 , pp. 1233-1239
    • Kim, S.J.1    Peppas, A.2    Hong, S.K.3
  • 97
    • 22544438179 scopus 로고    scopus 로고
    • Downregulation of peroxisome proliferator-activated receptor-alpha gene expression in a mouse model of ischemic cardiomyopathy is dependent on reactive oxygen species and prevents lipotoxicity
    • Dewald O., Sharma S., Adrogue J., et al. Downregulation of peroxisome proliferator-activated receptor-alpha gene expression in a mouse model of ischemic cardiomyopathy is dependent on reactive oxygen species and prevents lipotoxicity. Circulation 112 (2005) 407-415
    • (2005) Circulation , vol.112 , pp. 407-415
    • Dewald, O.1    Sharma, S.2    Adrogue, J.3
  • 98
    • 33746198000 scopus 로고    scopus 로고
    • Fatty acids attenuate insulin regulation of 5'-AMP-activated protein kinase and insulin cardioprotection after ischemia
    • Folmes C.D., Clanachan A.S., and Lopaschuk G.D. Fatty acids attenuate insulin regulation of 5'-AMP-activated protein kinase and insulin cardioprotection after ischemia. Circ Res 99 (2006) 61-68
    • (2006) Circ Res , vol.99 , pp. 61-68
    • Folmes, C.D.1    Clanachan, A.S.2    Lopaschuk, G.D.3
  • 99
    • 0033512660 scopus 로고    scopus 로고
    • Fatty acid oxidation in the reperfused ischemic heart
    • Kantor P.F., Dyck J.R., and Lopaschuk G.D. Fatty acid oxidation in the reperfused ischemic heart. Am J Med Sci 318 (1999) 3-14
    • (1999) Am J Med Sci , vol.318 , pp. 3-14
    • Kantor, P.F.1    Dyck, J.R.2    Lopaschuk, G.D.3
  • 100
    • 50549202600 scopus 로고
    • The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus
    • Randle P.J., Garland P.B., Hales C.N., et al. The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus. Lancet 1 (1963) 785-789
    • (1963) Lancet , vol.1 , pp. 785-789
    • Randle, P.J.1    Garland, P.B.2    Hales, C.N.3
  • 101
    • 0034687210 scopus 로고    scopus 로고
    • Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia
    • Marsin A.S., Bertrand L., Rider M.H., et al. Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia. Curr Biol 10 (2000) 1247-1255
    • (2000) Curr Biol , vol.10 , pp. 1247-1255
    • Marsin, A.S.1    Bertrand, L.2    Rider, M.H.3
  • 102
    • 0023162235 scopus 로고
    • The role of the sarcoplasmic reticulum in the response of ferret and rat heart muscle to acidosis
    • Orchard C.H. The role of the sarcoplasmic reticulum in the response of ferret and rat heart muscle to acidosis. J Physiol 384 (1987) 431-449
    • (1987) J Physiol , vol.384 , pp. 431-449
    • Orchard, C.H.1
  • 103
    • 0028153565 scopus 로고
    • Acidosis during ischemia promotes adenosine triphosphate resynthesis in post-ischemic rat heart
    • Bak M., and Ingwall J. Acidosis during ischemia promotes adenosine triphosphate resynthesis in post-ischemic rat heart. J Clin Invest 93 (1994) 40-49
    • (1994) J Clin Invest , vol.93 , pp. 40-49
    • Bak, M.1    Ingwall, J.2
  • 104
    • 33644662725 scopus 로고    scopus 로고
    • Chronic activation of PPARalpha is detrimental to cardiac recovery after ischemia
    • Sambandam N., Morabito D., Wagg C., et al. Chronic activation of PPARalpha is detrimental to cardiac recovery after ischemia. Am J Physiol Heart Circ Physiol 290 (2006) H87-H95
    • (2006) Am J Physiol Heart Circ Physiol , vol.290
    • Sambandam, N.1    Morabito, D.2    Wagg, C.3
  • 105
    • 0037428125 scopus 로고    scopus 로고
    • Hibernating myocardium retains metabolic and contractile reserve despite regional reductions in flow, function, and oxygen consumption at rest
    • Fallavollita J.A., Malm B.J., and Canty J.M.J. Hibernating myocardium retains metabolic and contractile reserve despite regional reductions in flow, function, and oxygen consumption at rest. Circ Res 92 (2003) 48-55
    • (2003) Circ Res , vol.92 , pp. 48-55
    • Fallavollita, J.A.1    Malm, B.J.2    Canty, J.M.J.3
  • 106
    • 0037046203 scopus 로고    scopus 로고
    • Adaptation and maladaptation of the heart in diabetes: part I: general concepts
    • Taegtmeyer H., McNulty P., and Young M.E. Adaptation and maladaptation of the heart in diabetes: part I: general concepts. Circulation 105 (2002) 1727-1733
    • (2002) Circulation , vol.105 , pp. 1727-1733
    • Taegtmeyer, H.1    McNulty, P.2    Young, M.E.3
  • 107
    • 0026705751 scopus 로고
    • Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors
    • Kliewer S.A., Umesono K., Noonan D.J., et al. Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors. Nature 358 (1992) 771-774
    • (1992) Nature , vol.358 , pp. 771-774
    • Kliewer, S.A.1    Umesono, K.2    Noonan, D.J.3
  • 108
    • 0032479423 scopus 로고    scopus 로고
    • Expression of putative fatty acid transporter genes are regulated by peroxisome proliferator-activated receptor alpha and gamma activators in a tissue- and inducer-specific manner
    • Motojima K., Passilly P., Peters J.M., et al. Expression of putative fatty acid transporter genes are regulated by peroxisome proliferator-activated receptor alpha and gamma activators in a tissue- and inducer-specific manner. J Biol Chem 273 (1998) 16710-16714
    • (1998) J Biol Chem , vol.273 , pp. 16710-16714
    • Motojima, K.1    Passilly, P.2    Peters, J.M.3
  • 109
    • 0028033268 scopus 로고
    • The peroxisome proliferator-activated receptor regulates mitochondrial fatty acid oxidative enzyme gene expression
    • Gulick T., Cresci S., Caira T., et al. The peroxisome proliferator-activated receptor regulates mitochondrial fatty acid oxidative enzyme gene expression. Proc Natl Acad Sci U S A 91 (1994) 11012-11016
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 11012-11016
    • Gulick, T.1    Cresci, S.2    Caira, T.3
  • 110
    • 0036143320 scopus 로고    scopus 로고
    • The cardiac phenotype induced by PPARalpha overexpression mimics that caused by diabetes mellitus
    • Finck B.N., Lehman J.J., Leone T.C., et al. The cardiac phenotype induced by PPARalpha overexpression mimics that caused by diabetes mellitus. J Clin Invest 109 (2002) 121-130
    • (2002) J Clin Invest , vol.109 , pp. 121-130
    • Finck, B.N.1    Lehman, J.J.2    Leone, T.C.3
  • 111
    • 0033749620 scopus 로고    scopus 로고
    • Signalling aspects of insulin resistance in skeletal muscle: mechanisms induced by lipid oversupply
    • Schmitz-Peiffer C. Signalling aspects of insulin resistance in skeletal muscle: mechanisms induced by lipid oversupply. Cell Signal 12 (2000) 583-594
    • (2000) Cell Signal , vol.12 , pp. 583-594
    • Schmitz-Peiffer, C.1
  • 112
    • 0033588253 scopus 로고    scopus 로고
    • Ceramide generation is sufficient to account for the inhibition of the insulin-stimulated PKB pathway in C2C12 skeletal muscle cells pretreated with palmitate
    • Schmitz-Peiffer C., Craig D.L., and Biden T.J. Ceramide generation is sufficient to account for the inhibition of the insulin-stimulated PKB pathway in C2C12 skeletal muscle cells pretreated with palmitate. J Biol Chem 274 (1999) 24202-24210
    • (1999) J Biol Chem , vol.274 , pp. 24202-24210
    • Schmitz-Peiffer, C.1    Craig, D.L.2    Biden, T.J.3
  • 113
    • 0033755148 scopus 로고    scopus 로고
    • Acyl-CoA inhibition of hexokinase in rat and human skeletal muscle is a potential mechanism of lipid-induced insulin resistance
    • Thompson A.L., and Cooney G.J. Acyl-CoA inhibition of hexokinase in rat and human skeletal muscle is a potential mechanism of lipid-induced insulin resistance. Diabetes 49 (2000) 1761-1765
    • (2000) Diabetes , vol.49 , pp. 1761-1765
    • Thompson, A.L.1    Cooney, G.J.2
  • 114
    • 0032792498 scopus 로고    scopus 로고
    • Mechanism responsible for inactivation of skeletal muscle pyruvate dehydrogenase complex in starvation and diabetes
    • Wu P., Inskeep K., Bowker-Kinley M.M., et al. Mechanism responsible for inactivation of skeletal muscle pyruvate dehydrogenase complex in starvation and diabetes. Diabetes 48 (1999) 1593-1599
    • (1999) Diabetes , vol.48 , pp. 1593-1599
    • Wu, P.1    Inskeep, K.2    Bowker-Kinley, M.M.3
  • 115
    • 0342506484 scopus 로고    scopus 로고
    • Regulation of energy substrate metabolism in the diabetic heart
    • Stanley W.C., Lopaschuk G.D., and McCormack J.G. Regulation of energy substrate metabolism in the diabetic heart. Cardiovasc Res 34 (1997) 25-33
    • (1997) Cardiovasc Res , vol.34 , pp. 25-33
    • Stanley, W.C.1    Lopaschuk, G.D.2    McCormack, J.G.3
  • 116
    • 0021685840 scopus 로고
    • The effects of acute and chronic diabetes on myocardial metabolism in rats
    • Chen V., Ianuzzo C., Fong B., et al. The effects of acute and chronic diabetes on myocardial metabolism in rats. Diabetes 33 (1984) 1078-1084
    • (1984) Diabetes , vol.33 , pp. 1078-1084
    • Chen, V.1    Ianuzzo, C.2    Fong, B.3
  • 117
    • 0033841128 scopus 로고    scopus 로고
    • Streptozotocin-induced changes in cardiac gene expression in the absence of severe contractile dysfunction
    • Depre C., Young M.E., Ying J., et al. Streptozotocin-induced changes in cardiac gene expression in the absence of severe contractile dysfunction. J Mol Cell Cardiol 32 (2000) 985-996
    • (2000) J Mol Cell Cardiol , vol.32 , pp. 985-996
    • Depre, C.1    Young, M.E.2    Ying, J.3
  • 118
    • 0035085845 scopus 로고    scopus 로고
    • Uncoupling protein 3 transcription is regulated by peroxisome proliferator-activated receptor (alpha) in the adult rodent heart
    • Young M.E., Patil S., Ying J., et al. Uncoupling protein 3 transcription is regulated by peroxisome proliferator-activated receptor (alpha) in the adult rodent heart. FASEB J 15 (2001) 833-845
    • (2001) FASEB J , vol.15 , pp. 833-845
    • Young, M.E.1    Patil, S.2    Ying, J.3
  • 119
    • 0034652225 scopus 로고    scopus 로고
    • Lipotoxic heart disease in obese rats: implications for human obesity
    • Zhou Y.T., Grayburn P., Karim A., et al. Lipotoxic heart disease in obese rats: implications for human obesity. Proc Natl Acad Sci U S A 97 (2000) 1784-1789
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 1784-1789
    • Zhou, Y.T.1    Grayburn, P.2    Karim, A.3
  • 120
    • 0036326045 scopus 로고    scopus 로고
    • Impaired long-chain fatty acid oxidation and contractile dysfunction in the obese Zucker rat heart
    • Young M.E., Guthrie P.H., Razeghi P., et al. Impaired long-chain fatty acid oxidation and contractile dysfunction in the obese Zucker rat heart. Diabetes 51 (2002) 2587-2595
    • (2002) Diabetes , vol.51 , pp. 2587-2595
    • Young, M.E.1    Guthrie, P.H.2    Razeghi, P.3
  • 121
    • 7744234747 scopus 로고    scopus 로고
    • Intramyocardial lipid accumulation in the failing human heart resembles the lipotoxic rat heart
    • Sharma S., Adrogue J.V., Golfman L., et al. Intramyocardial lipid accumulation in the failing human heart resembles the lipotoxic rat heart. FASEB J 18 (2004) 1692-1700
    • (2004) FASEB J , vol.18 , pp. 1692-1700
    • Sharma, S.1    Adrogue, J.V.2    Golfman, L.3
  • 122
    • 0033861608 scopus 로고    scopus 로고
    • Involvement of protein kinase C in human skeletal muscle insulin resistance and obesity
    • Itani S.I., Zhou Q., Pories W.J., et al. Involvement of protein kinase C in human skeletal muscle insulin resistance and obesity. Diabetes 49 (2000) 1353-1358
    • (2000) Diabetes , vol.49 , pp. 1353-1358
    • Itani, S.I.1    Zhou, Q.2    Pories, W.J.3
  • 123
    • 33748419255 scopus 로고    scopus 로고
    • Association of plasma free fatty acids and left ventricular diastolic function in patients with clinically severe obesity
    • Leichman J.G., Aguilar D., King T.M., et al. Association of plasma free fatty acids and left ventricular diastolic function in patients with clinically severe obesity. Am J Clin Nutr 84 (2006) 336-341
    • (2006) Am J Clin Nutr , vol.84 , pp. 336-341
    • Leichman, J.G.1    Aguilar, D.2    King, T.M.3
  • 124
    • 0023275573 scopus 로고
    • Correction of hyperglycemia with phlorizin normalizes tissue sensitivity to insulin in diabetic rats
    • Rossetti L., Smith D., Shulman G.I., et al. Correction of hyperglycemia with phlorizin normalizes tissue sensitivity to insulin in diabetic rats. J Clin Invest 79 (1987) 1510-1515
    • (1987) J Clin Invest , vol.79 , pp. 1510-1515
    • Rossetti, L.1    Smith, D.2    Shulman, G.I.3
  • 125
    • 0034680797 scopus 로고    scopus 로고
    • Glucose down-regulates the expression of the peroxisome proliferator-activated receptor-alpha gene in the pancreatic beta-cell
    • Roduit R., Morin J., Masse F., et al. Glucose down-regulates the expression of the peroxisome proliferator-activated receptor-alpha gene in the pancreatic beta-cell. J Biol Chem 275 (2000) 35799-35806
    • (2000) J Biol Chem , vol.275 , pp. 35799-35806
    • Roduit, R.1    Morin, J.2    Masse, F.3
  • 126
    • 0025822785 scopus 로고
    • Isolation and characterization of the mouse cardiac myosin heavy chain genes
    • Gulick J., Subramaniam A., Neumann J., et al. Isolation and characterization of the mouse cardiac myosin heavy chain genes. J Biol Chem 266 (1991) 9180-9185
    • (1991) J Biol Chem , vol.266 , pp. 9180-9185
    • Gulick, J.1    Subramaniam, A.2    Neumann, J.3
  • 127
    • 0029598487 scopus 로고
    • Identification of a contractile-responsive element in the cardiac alpha-myosin heavy chain gene
    • Ojamaa K., Samarel A.M., and Klein I. Identification of a contractile-responsive element in the cardiac alpha-myosin heavy chain gene. J Biol Chem 270 (1995) 31276-31281
    • (1995) J Biol Chem , vol.270 , pp. 31276-31281
    • Ojamaa, K.1    Samarel, A.M.2    Klein, I.3
  • 128
    • 23044450269 scopus 로고    scopus 로고
    • Activation of PPARgamma enhances myocardial glucose oxidation and improves contractile function in isolated working hearts of ZDF rats
    • Golfman L.S., Wilson C.R., Sharma S., et al. Activation of PPARgamma enhances myocardial glucose oxidation and improves contractile function in isolated working hearts of ZDF rats. Am J Physiol Endocrinol Metab 289 (2005) E328-E336
    • (2005) Am J Physiol Endocrinol Metab , vol.289
    • Golfman, L.S.1    Wilson, C.R.2    Sharma, S.3
  • 129
    • 0029800177 scopus 로고    scopus 로고
    • Fatty acid oxidation enzyme gene expression is downregulated in the failing heart
    • Sack M.N., Rader T.A., Park S., et al. Fatty acid oxidation enzyme gene expression is downregulated in the failing heart. Circulation 94 (1996) 2837-2842
    • (1996) Circulation , vol.94 , pp. 2837-2842
    • Sack, M.N.1    Rader, T.A.2    Park, S.3
  • 130
    • 0037125371 scopus 로고    scopus 로고
    • Altered myocardial fatty acid and glucose metabolism in idiopathic dilated cardiomyopathy
    • Davila-Roman V.G., Vedala G., Herrero P., et al. Altered myocardial fatty acid and glucose metabolism in idiopathic dilated cardiomyopathy. J Am Coll Cardiol. 40 (2002) 271-277
    • (2002) J Am Coll Cardiol. , vol.40 , pp. 271-277
    • Davila-Roman, V.G.1    Vedala, G.2    Herrero, P.3
  • 131
    • 0009970051 scopus 로고
    • Studies on myocardial metabolism. VI. Myocardial metabolism in congestive failure
    • Blain J.M., Schafer H., Siegel A.L., et al. Studies on myocardial metabolism. VI. Myocardial metabolism in congestive failure. Am J Med 20 (1956) 820-833
    • (1956) Am J Med , vol.20 , pp. 820-833
    • Blain, J.M.1    Schafer, H.2    Siegel, A.L.3
  • 132
    • 11144344187 scopus 로고    scopus 로고
    • PPAR-gamma agonist rosiglitazone ameliorates ventricular dysfunction in experimental chronic mitral regurgitation
    • Nemoto S., Razeghi P., Ishiyama M., et al. PPAR-gamma agonist rosiglitazone ameliorates ventricular dysfunction in experimental chronic mitral regurgitation. Am J Physiol Heart Circ Physiol 288 (2005) H77-H82
    • (2005) Am J Physiol Heart Circ Physiol , vol.288
    • Nemoto, S.1    Razeghi, P.2    Ishiyama, M.3


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