Fatty acids attenuate insulin regulation of 5′-AMP-activated protein kinase and insulin cardioprotection after ischemia

Circulation Research

Volumn 99, Issue 1, 2006, Pages 61-68

  Folmes, Clifford D L ^a   Clanachan, Alexander S ^a   Lopaschuk, Gary D ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Fatty acid oxidation; Glucose oxidation; Glycolysis; Ischemia reperfusion; Proton production

Indexed keywords

ADENOSINE PHOSPHATE; FATTY ACID; INSULIN; PALMITIC ACID; PROTEIN KINASE; 5' AMP ACTIVATED PROTEIN KINASE; 5'-AMP-ACTIVATED PROTEIN KINASE; CARDIOTONIC AGENT; GLUCOSE; HYPERGLYCEMIC AGENT; MULTIENZYME COMPLEX; PALMITIC ACID DERIVATIVE; PROTEIN SERINE THREONINE KINASE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; GLUCOSE OXIDATION; GLUCOSE TRANSPORT; GLYCOLYSIS; HEART CONTRACTION; HEART MUSCLE METABOLISM; HEART PERFUSION; HEART PROTECTION; INSULIN SYNTHESIS; ISCHEMIA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTON TRANSPORT; REPERFUSION; ANIMAL; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; IN VITRO STUDY; METABOLISM; MOUSE STRAIN; OXIDATION REDUCTION REACTION;

ANIMALS; CARDIOTONIC AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; GLUCOSE; GLYCOLYSIS; INSULIN; INSULIN ANTAGONISTS; MICE; MICE, INBRED STRAINS; MULTIENZYME COMPLEXES; MYOCARDIAL ISCHEMIA; MYOCARDIAL REPERFUSION; OXIDATION-REDUCTION; PALMITATES; PROTEIN-SERINE-THREONINE KINASES;

EID: 33746198000     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000229656.05244.11     Document Type: Article

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