Streptozotocin-induced changes in cardiac gene expression in the absence of severe contractile dysfunction

Journal of Molecular and Cellular Cardiology

Volumn 32, Issue 6, 2000, Pages 985-996

  Depre, Christophe ^a   Young, Martin E ^a   Ying, Jun ^a   Ahuja, Harleen Singh ^a   Han, Qiuying ^a   Garza, Nicole ^a   Davies, Peter J A ^a   Taegtmeyer, Heinrich ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

Carnitine palmitoyltransferase I; Diabetes; Glucose transporters; Myosin heavy chain isoforms; Quantitative PCR

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); CARNITINE PALMITOYLTRANSFERASE; CREATINE KINASE; GLUCOSE TRANSPORTER; MYOSIN HEAVY CHAIN; STREPTOZOCIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION REGULATION; HEART FAILURE; HEART MUSCLE CONTRACTILITY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; STREPTOZOCIN DIABETES;

ANIMALIA;

EID: 0033841128     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.2000.1139     Document Type: Article

References (62)

1. Regulation of energy substrate metabolism in the diabetic heart
2. Energy metabolism of the heart: From basic concepts to clinical applications
3. The mitochondrial carnitine palmitoyltransferase system. From concept to molecular analysis
4. Regulation of fatty acid oxidation in the mammalian heart in health and disease
5. Effect of diabetes and fasting on GLUT-4 (muscle/fat) glucose-transporter expression in insulin-sensitive tissues
6. Myosin isoenzymic changes in several models of rat cardiac hypertrophy
7. Myosin heavy chain messenger RNA and protein isoform transitions during cardiac hypertrophy
8. Switches in cardiac muscle gene expression as a result of pressure and volume overload
9. Hemodynamic regulation of myosin heavy chain expression
10. Changes in expression of heart carnitine palmitoyltransferase I isoforms with electrical stimulation of cultures rat neonatal cardiac myocytes
11. A role for Sp and nuclear receptor transcription factors in a cardiac hypertrophy growth program
12. Decreased GLUT-4 mRNA content and insulin-sensitive deoxyglucose uptake show insulin resistance in the hypertensive rat heart
13. Unloaded heart in vivo replicates fetal gene expression of cardiac hypertrophy
14. Glucose Oxidation rates in fatty acid-perfused isolated working hearts from diabetic rat
15. Diabetes mellitus induces changes in cardiac myosin of the rat
16. The effects of streptozotocin-induced diabetes in rats on cardiac contractile proteins
17. Defective sarcoplasmic reticular transport in diabetic cardio-myopathy
18. Cardiac sarcoplasmic reticulum function in insulin- or carnitine-treated diabetic rats
19. Subcellular remodeling and heart dysfunction in chronic diabetes
20. Metabolic disturbances in diabetic cardiomyopathy
21. Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction
22. Real time quantitative PCR
23. A novel method for real time quantitative RT-PCR
24. 36B4 cDNA used as an estradiol-independent mRNA control is the cDNA for human acidic ribosomal phosphoprotein PO
25. Targeted overexpression of protein kinase C β2 isoform in myocardium causes cardiomyopathy
26. Rat heart expresses two forms of mitochondrial carnitine palmitoyltransferase I
27. Streptozotocin treatment up-regulates uncoupling protein 3 expression in the rat heart
28. Basis for myocardial mechanical defects associated with non-insulin-dependent diabetes
29. Depressed sarcoplasmic reticular function for diabetic rats
30. Abnormal cardiac function in the streptozotocin-diabetic rat
31. Glucose transporter gene expression: Regulation of transcription and mRNA stability
32. Tumor necrosis factor-α-induced insulin resistance in 3T3-L1 adipocytes is accompanied by a loss of insulin receptor substrate-1 and GLUT4 expression without a loss of insulin receptor-mediated signal transduction
33. Tumor necrosis factor in the heart
34. Cyclooxygenase-2 induction in congestive heart failure
35. Cardiac sarcoplasmic reticulum function and gene expression in chronic diabetes
36. Control of cardiac gene expression by mechanical stress
37. The vascular smooth muscle alpha-actin gene is reactivated during cardiac hypertrophy provoked by load
38. Segregation of atrial-specific and inducible expression of an atrial natriuretic factor transgene in an in vivo murine model of cardiac hypertrophy
39. Proto-oncogene induction and reprogramming of cardiac gene expression produced by pressure overload
40. Modulation of cardiac genes by mechanical stress. The oncogene signalling hypothesis
41. Serum response factor mediates AP-1-dependent induction of the skeletal α-actin promoter in ventricular myocytes
42. The cellular and molecular response of cardiac myocytes to mechanical stress
43. Growth factors, proto-oncogenes, and plasticity of the cardiac phenotype
44. Glucose for the heart
45. Myocyte enhancer factor 2 (MEF2) binding site is essential for C2C12 myotube-specific expression of the rat GLUT4/muscle-adipose facilitative glucose transporter
46. Myocyte enhancer factor 2 (MEF2)-binding site is required for GLUT4 gene expression in transgenic mice
47. Transcription of the rat sarcoplasmic reticulum Ca2 + adenosine triphosphatase gene is increased by 3,5,3'-triiodothyronine receptor isoform-specific interactions with the myocyte-specific enhancer factor-2a
48. Myocyte-specific enhancer factor 2 and thyroid hormone receptor associate and synergistically activate the α-cardiac myosin heavy-chain gene
49. Characterization and expression of human HepG2/erythrocyte glucose-transporter gene
50. Insulin signal transduction and the IRS proteins
51. A role for Raf-1 in the divergent signaling pathways mediating insulin-stimulated glucose transport
52. Acetyl-CoA carboxylase regulation of fatty acid oxidation in the heart
53. Control of human muscle-type carnitine palmitoyltransferase I gene transcription by peroxisome proliferator-activated receptor
54. Cloning and characterization of the promoter for the liver isoform of the rat carnitine palmitoyltransferase I (L-CPT I) gene
55. Hepatic expression of CCAAT/enhancer binding protein alpha: Hormonal and metabolic regulation in rats
56. Molecular basis of cardiac performance: Plasticity of the myocardium generated through protein isoform switches
57. Cardiomyopathy associated with non-insulin-dependent diabetes
58. Myosin heavy chain regulation and myocyte contractile depression after LV hypertrophy in aortic-banded mice
59. Post-transcriptional gene regulatory mechanisms in eukaryotes: An overview
60. Contraction accelerates myosin heavy chain synthesis rates in adult cardiocytes by an increase in the rate of translational initiation
61. Sarco(endo)plasmic reticulum calcium pumps in the cardiovascular system: Function and gene expression
62. Hypertensive-diabetic cardiomyopathy in the rat