Poly (ADP-ribose) polymerase activity regulates apoptosis in HeLa cells after alkylating DNA damage

Cancer Biology and Therapy

Volumn 7, Issue 6, 2008, Pages 934-941

  Liu, Xuesong ^a   Luo, Xu ^b   Shi, Yan ^a   Zhu, Gui Dong ^a   Penning, Thomas ^a   Giranda, Vincent L ^a   Luo, Yan ^a  

^a ABBOTT LABORATORIES   (United States)

^b NEBRASKA MEDICAL CENTER   (United States)

Author keywords

ABT 888; Apoptosis; ATP; MNNG; Necrosis; PARP

Indexed keywords

1,5 ISOQUINOLINEDIOL; 3 AMINOBENZAMIDE; 8 HYDROXY 2 METHYL 4(3H) QUINAZOLINONE; ABT 888; ADENOSINE TRIPHOSPHATE; BENZYLOXYCARBONYLVALYLALANYLASPARTIC ACID; CASPASE 3; CASPASE INHIBITOR; CYTOCHROME C; DIMETHYL SULFOXIDE; METHYLNITRONITROSOGUANIDINE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; OLIGOMYCIN; PROTEIN BAK; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; SMALL INTERFERING RNA; 2 ((R) 2 METHYLPYRROLIDIN 2 YL) 1H BENZIMIDAZOLE 4 CARBOXAMIDE; 2-((R)-2-METHYLPYRROLIDIN-2-YL)-1H-BENZIMIDAZOLE-4-CARBOXAMIDE; ALKYLATING AGENT; BENZIMIDAZOLE DERIVATIVE; NICOTINAMIDE ADENINE DINUCLEOTIDE;

APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; CYTOSOL; DNA ALKYLATION; DNA DAMAGE; DOWN REGULATION; DRUG MECHANISM; DRUG POTENTIATION; ENZYME ACTIVITY; ENZYME INHIBITION; FIBROBLAST; HELA CELL; HUMAN; HUMAN CELL; MITOCHONDRION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SECRETION; REGULATORY MECHANISM; ANIMAL; CHEMISTRY; GENE EXPRESSION REGULATION; METABOLISM; MOUSE;

ALKYLATING AGENTS; ANIMALS; APOPTOSIS; BENZIMIDAZOLES; CYTOCHROMES C; DNA DAMAGE; FIBROBLASTS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HELA CELLS; HUMANS; METHYLNITRONITROSOGUANIDINE; MICE; NAD; OLIGOMYCINS; POLY(ADP-RIBOSE) POLYMERASES;

EID: 46749100904     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.7.6.5933     Document Type: Article

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