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Volumn 89, Issue 6, 2003, Pages 1222-1234

Non-apoptogenic killing of hela cervical carcinoma cells after short exposure to the alkylating agent N-methyl-N′-nitro-N-nitrosoguanidine (MNNG)

Author keywords

AIF translocation; Apoptosis; Caspase 3 activation; Comet assay; Cytochrome c; Degradation of PARP 1; Inactivation of PARP 1; Necrosis; P53 activation; Single cell gel electrophoresis

Indexed keywords

ALKYLATING AGENT; CASPASE 3; CISPLATIN; CYTOCHROME C; DPQ; ETOPOSIDE; METHYLNITRONITROSOGUANIDINE; N (5,6 DIHYDRO 6 OXO 2 PHENANTHRIDINYL) 2 DIMETHYLAMINOACETAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN P53;

EID: 0042195867     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcb.10586     Document Type: Article
Times cited : (18)

References (30)
  • 1
    • 0021997074 scopus 로고
    • Poly(ADP-ribose) in the cellular response to DNA damage
    • Berger NA. 1985. Poly(ADP-ribose) in the cellular response to DNA damage. Radiat Res 101:4-15.
    • (1985) Radiat Res , vol.101 , pp. 4-15
    • Berger, N.A.1
  • 2
    • 0037051095 scopus 로고    scopus 로고
    • p53: An ubiquitous target of anticancer drugs
    • Blagosklonny MV. 2002. p53: An ubiquitous target of anticancer drugs. Int J Cancer 98:161-166.
    • (2002) Int J Cancer , vol.98 , pp. 161-166
    • Blagosklonny, M.V.1
  • 3
    • 0034680776 scopus 로고    scopus 로고
    • Nuclear translocation of mismatch repair proteins MSH2 and MSH6 as a response of cells at alkylating agents
    • Christmann M, Kaina B. 2000. Nuclear translocation of mismatch repair proteins MSH2 and MSH6 as a response of cells at alkylating agents. J Biol Chem 275:36256-36262.
    • (2000) J Biol Chem , vol.275 , pp. 36256-36262
    • Christmann, M.1    Kaina, B.2
  • 4
    • 2942707103 scopus 로고
    • Papillomavirus sequences integrate near cellular oncogenes in some cervical carcinomas
    • Durst M, Croce CM, Gissmann L, Schwarz E, Huebner K. 1987. Papillomavirus sequences integrate near cellular oncogenes in some cervical carcinomas. Proc Natl Acad Sci USA 84:1070-1074.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 1070-1074
    • Durst, M.1    Croce, C.M.2    Gissmann, L.3    Schwarz, E.4    Huebner, K.5
  • 6
    • 0033576675 scopus 로고    scopus 로고
    • More than one way to die: Apoptosis, necrosis and reactive oxygen damage
    • Fiers W, Beyaert R, Declercq W, Vandenabeele P. 1999. More than one way to die: Apoptosis, necrosis and reactive oxygen damage. Oncogene 18:7719-7730.
    • (1999) Oncogene , vol.18 , pp. 7719-7730
    • Fiers, W.1    Beyaert, R.2    Declercq, W.3    Vandenabeele, P.4
  • 7
    • 0033910863 scopus 로고    scopus 로고
    • Apoptosis-related activities measured with isolated mitochondria and digitonin-permeabilized cells
    • Fiskum G, Kowaltowksi AJ, Andreyev AY, Kushnareva YE, Starkov AA. 2000. Apoptosis-related activities measured with isolated mitochondria and digitonin-permeabilized cells. Methods Enzymol 322:222-234.
    • (2000) Methods Enzymol , vol.322 , pp. 222-234
    • Fiskum, G.1    Kowaltowksi, A.J.2    Andreyev, A.Y.3    Kushnareva, Y.E.4    Starkov, A.A.5
  • 8
    • 0026550131 scopus 로고
    • Efficiency of binding the retinoblastoma protein correlates with the transforming capacity of the E7 oncoproteins of the human papillomaviruses
    • Heck DV, Yee CL, Howley PM, Munger K. 1992. Efficiency of binding the retinoblastoma protein correlates with the transforming capacity of the E7 oncoproteins of the human papillomaviruses. Proc Natl Acad Sci USA 89:4442-4446.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 4442-4446
    • Heck, D.V.1    Yee, C.L.2    Howley, P.M.3    Munger, K.4
  • 9
    • 0034599103 scopus 로고    scopus 로고
    • A public domain image analysis program for the single cell gel electrophoresis (Comet) assay
    • Helma C, Uhl M. 2000. A public domain image analysis program for the single cell gel electrophoresis (Comet) assay. Mutat Res 466:9-15.
    • (2000) Mutat Res , vol.466 , pp. 9-15
    • Helma, C.1    Uhl, M.2
  • 10
    • 0035081855 scopus 로고    scopus 로고
    • Segregation of nucleolar components coincides with caspase-3 activation in cisplatin-treated HeLa cells
    • Horky M, Wurzer G, Kotala V, Anton M, Vojtesek B, Vacha J, Wesierska-Gadek J. 2001. Segregation of nucleolar components coincides with caspase-3 activation in cisplatin-treated HeLa cells. J Cell Sci 114:663-670.
    • (2001) J Cell Sci , vol.114 , pp. 663-670
    • Horky, M.1    Wurzer, G.2    Kotala, V.3    Anton, M.4    Vojtesek, B.5    Vacha, J.6    Wesierska-Gadek, J.7
  • 12
    • 0032533856 scopus 로고    scopus 로고
    • Functional interaction of p53 with poly(ADP-ribose) polymerase (PARP) during apoptosis following DNA damage: Covalent poly(ADP-ribosyl)ation of p53 by exogenous PARP and noncovalent binding of p53 to the Mr 85,000 proteolytic fragment
    • Kumari SR, Mendoza-Alvarez H, Alvarez-Gonzalez R. 1998. Functional interaction of p53 with poly(ADP-ribose) polymerase (PARP) during apoptosis following DNA damage: covalent poly(ADP-ribosyl)ation of p53 by exogenous PARP and noncovalent binding of p53 to the Mr 85,000 proteolytic fragment. Cancer Res 58:5075-5078.
    • (1998) Cancer Res , vol.58 , pp. 5075-5078
    • Kumari, S.R.1    Mendoza-Alvarez, H.2    Alvarez-Gonzalez, R.3
  • 13
    • 0036682299 scopus 로고    scopus 로고
    • Action of a novel anticancer agent, CHS 828, on mouse fibroblasts: Increased sensitivity of cells lacking poly(ADP-ribose) polymerase-1
    • Lövborg H, Wojciechowski J, Larsson R, Wesierska-Gadek J. 2002. Action of a novel anticancer agent, CHS 828, on mouse fibroblasts: Increased sensitivity of cells lacking poly(ADP-ribose) polymerase-1. Cancer Res 62:4206-4211.
    • (2002) Cancer Res , vol.62 , pp. 4206-4211
    • Lövborg, H.1    Wojciechowski, J.2    Larsson, R.3    Wesierska-Gadek, J.4
  • 14
    • 0034667383 scopus 로고    scopus 로고
    • 6-methylguanine is Bcl-2 and caspase-9/3 regulated and Fas/caspase-8 independent
    • 6-methylguanine is Bcl-2 and caspase-9/3 regulated and Fas/caspase-8 independent. Cancer Res 60:5815-5824.
    • (2000) Cancer Res , vol.60 , pp. 5815-5824
    • Ochs, K.1    Kaina, B.2
  • 15
    • 0035295778 scopus 로고    scopus 로고
    • Mitochondria in apoptosis and human disease
    • Olson M, Kornbluth S. 2001. Mitochondria in apoptosis and human disease. Curr Mol Med 1:91-122.
    • (2001) Curr Mol Med , vol.1 , pp. 91-122
    • Olson, M.1    Kornbluth, S.2
  • 16
    • 0029664534 scopus 로고    scopus 로고
    • 6-methylguanine-DNA methyltransferase (MGMT) on the cytotoxic and recombinogenic activity of different antineoplastic drugs
    • 6-methylguanine-DNA methyltransferase (MGMT) on the cytotoxic and recombinogenic activity of different antineoplastic drugs. Int J Cancer 65:506-512.
    • (1996) Int J Cancer , vol.65 , pp. 506-512
    • Preuss, I.1    Thust, R.2    Kaina, B.3
  • 17
    • 0035909485 scopus 로고    scopus 로고
    • Contribution of apoptosis to responses in the comet assay
    • Roser S, Pool-Zobel B-L, Rechkemmer G. 2001. Contribution of apoptosis to responses in the comet assay. Mut Res 497:169-175.
    • (2001) Mut Res , vol.497 , pp. 169-175
    • Roser, S.1    Pool-Zobel, B.-L.2    Rechkemmer, G.3
  • 18
    • 0025639158 scopus 로고
    • The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53
    • Scheffner M, Werness BA, Huibregtse JM, Levine AJ, Howley PM. 1990. The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53. Cell 63:1129-1136.
    • (1990) Cell , vol.63 , pp. 1129-1136
    • Scheffner, M.1    Werness, B.A.2    Huibregtse, J.M.3    Levine, A.J.4    Howley, P.M.5
  • 20
    • 0001510491 scopus 로고    scopus 로고
    • The RB and p53 pathways in cancer
    • Sherr CJ, McCormick F. 2002. The RB and p53 pathways in cancer. Cancer Cell 2:103-112.
    • (2002) Cancer Cell , vol.2 , pp. 103-112
    • Sherr, C.J.1    McCormick, F.2
  • 21
    • 0023919963 scopus 로고
    • A simple technique for quantitation of low levels of DNA damage in individual cells
    • Singh NP, McCoy M, Tice RR, Schneider E. 1988. A simple technique for quantitation of low levels of DNA damage in individual cells. Exp Cell Res 175:184-191.
    • (1988) Exp Cell Res , vol.175 , pp. 184-191
    • Singh, N.P.1    McCoy, M.2    Tice, R.R.3    Schneider, E.4
  • 23
    • 0035240260 scopus 로고    scopus 로고
    • Apoptosis: Implications of basic research for clinical oncology
    • Tamm I, Schriever F, Dorken B. 2001. Apoptosis: Implications of basic research for clinical oncology. Lancet Oncol 2:33-42.
    • (2001) Lancet Oncol , vol.2 , pp. 33-42
    • Tamm, I.1    Schriever, F.2    Dorken, B.3
  • 25
    • 0028190116 scopus 로고
    • Apoptosis and programmed cell death in health and disease
    • Vermes I, Haanen C. 1994. Apoptosis and programmed cell death in health and disease. Adv Clin Chem 31:177-246.
    • (1994) Adv Clin Chem , vol.31 , pp. 177-246
    • Vermes, I.1    Haanen, C.2
  • 26
    • 0020530724 scopus 로고
    • A detergent-trypsin method for the preparation of nuclei for flow cytometric DNA analysis
    • Vindelov LL, Christensen IJ, and Nissen NI. 1983. A detergent-trypsin method for the preparation of nuclei for flow cytometric DNA analysis. Cytometry 3:323-327.
    • (1983) Cytometry , vol.3 , pp. 323-327
    • Vindelov, L.L.1    Christensen, I.J.2    Nissen, N.I.3
  • 29
    • 0037056222 scopus 로고    scopus 로고
    • Escape of p53 protein from E6-mediated degradation in HeLa cells after cisplatin therapy
    • Wesierska-Gadek J, Schloffer D, Kotala V, Horky M. 2002. Escape of p53 protein from E6-mediated degradation in HeLa cells after cisplatin therapy. Int J Cancer 101:128-136.
    • (2002) Int J Cancer , vol.101 , pp. 128-136
    • Wesierska-Gadek, J.1    Schloffer, D.2    Kotala, V.3    Horky, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.