Apoptosis and necrosis: Intracellular ATP level as a determinant for cell death modes

Cell Death and Differentiation

Volumn 4, Issue 6, 1997, Pages 429-434

  Tsujimoto, Yoshihide ^a  

^a OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

Author keywords

Apoptosis; ATP; bcl 2; Caspase; Mitochondria; Necrosis

Indexed keywords

EID: 0000322764     PISSN: 13509047     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cdd.4400262     Document Type: Article

References (30)

1. Akao Y, Otsuki Y, Kataoka S, Ito Y and Tsujimoto Y (1994) Multiple subcellular localization of bcl-2: Detection in nuclear outer membrane, endoplasmic reticulum membrane and mitochondrial membranes. Cancer Res. 54: 2468-2471
2. Alison MR and Sarraf CE (1994) Liver cell death: patterns and mechanisms. Gut 35: 577-581
3. Alnemri ES, Livingston DJ, Nicholson DW, Salvesen G, Thomberry NA, Wong WW and Yuan J (1996) Human ICE/CED-3 protease nomenclature. Cell 87: 171
4. Armstrong RC, Aja T, Xiang J, Gaur S, Krebs JF, Hoang K, Bai X, Korsmeyer SJ, Karanewsky DS, Fritz LC and Tomaselli KJ (1996) Fas-induced activation of the cell death-related protease CPP32 is inhibited by Bcl-2 and by ICE family protease inhibitors. J. Biol. Chem. 271: 16850-16855
5. Boulakia CA, Chen G, Ng FWH, Teodoro JG, Branton PE, Nicholson DW, Poirier GG and Shore GC (1996) Bcl-2 and adenovirus E1B 19 kDA protein prevent E1A-induced processing of CPP32 and cleavage of poly (ADP-ribose) polymerase. Oncogene 12: 529-535
6. Charriaut-Marlangue C, Aggoun-Zouaoui D, Repress A and Ben-Ari Y (1996) Apoptotic features of selective neuronal death in ischemia, epilepsy and gp 120 toxicity. Trends Neurosci. 19: 109-114
7. Chinnaiyan AM, Orth K, O'Rouke K, Duan H, Poirier GG and Dixit VM (1996) Molecular ordering of the cell death pathway: Bcl-2 and Bcl-xL function upstream of the Ced-3-like apoptotic proteases. J. Biol. Chem. 271: 4573-4576
8. Chinnaiyan AM, O'Rourke K, Lane BR and Dixit VM (1997) Interaction of CED-4 with CED-3 and CED-9: A molecular framework for cell death. Science 275: 1122-1126
9. Clem RJ and Miller LK (1994) Induction and inhibition of apoptosis by insect viruses. In: Tomei LD and Cope FO (eds) Apoptosis II: The molecular basis of apoptosis in diseases. pp 89 -110, Cold Spring Harbor Laboratory Press
10. Cory S (1995) Regulation of lymphocyte survival by the bcl-2 gene family. Ann. Rev. Immunol. 13: 513-543
11. Enari M, Talanian RV, Wong WW and Nagata S (1996) Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis. Nature 380: 723-726
12. Eguchi Y, Shimizu S and Tsujimoto Y (1997) Intracellular ATP levels determine cell death fate by apoptosis or necrosis. Cancer Res. in press
13. Hawkins HK, Ericsson JLE, Biberfeld P and Trump BF (1972) Lysosome and phagosome stability in lethal cell injury. Morphologic tracer studies in cell injury due to inhibition of energy metabolism, immune cytolysis and photosensitization. Am. J. Pathol. 68: 255-258
14. Hay BA, Wassarman DA and Rubin GM (1995) Drosophila homologs of Baculovirus inhibitor of apoptosis proteins function to block cell death. Cell 83: 1253-1262
15. Hockenbery D, Nunez G, Milliman C, Schreber RD and Korsmeyer SJ (1990) Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature 348: 334-336
16. Jacobson MD, Burne JF, King MP, Miyashita T, Reed JC and Raff MC (1993) Bcl-2 blocks apoptosis in cells lacking mitochondrial DNA. Nature 361: 365-369
17. Kane DJ, Sarafian TA, Anton R, Hahn H, Gralla EB, Valentine JS, Ord T and Bredesen DE (1993) Bcl-2 inhibition of neural death: Decreased generation of reactive oxygen species. Science 262: 1274-1277
18. Kane DJ, Ord T, Anton R and Bredesen DE (1995) Expression of bcl-2 inhibits necrotic neural cell death. J. Neurosci. Res. 40: 269-275
19. Kass GE, Ericksson JE, Weis M, Orrenius S and Chow SC (1996) Chromatin condensation during apoptosis requires ATP. Biochem. J. 318: 749-752
20. Kluck RM, Bossy-Wefzel E, Green DR and Newmeyer DD (1997) The release of cytochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis. Science 275: 1132-1136
21. Kroemer G (1997) Mitochondrial implication in apoptosis. Towards an endosymbiont hypothesis of apoptosis evolution. Cell Death and Differ. 4: 443-456
22. Kumar S (1995) ICE-like proteases in apoptosis. TIBS 20: 198-202
23. Ledda-Columbano GM and Columbano A (1991 ) Apoptosis and hepatocarcinogenesis, In: Tomei LD and Cope FO (eds), Apoptosis: The molecular basis of cell death. pp 101-119. Cold Spring Harbor Laboratory Press
24. Leist M, Single B, Castoldi AF, Kenle S and Nicotera P (1997) Intracellular ATP concentration: a switch deciding between apoptosis and necrosis. J. Exp. Med. in press
25. Liu X, Kim CN, Yang J, Lemmerson R and Wang X (1996) Induction of apoptotic program in cell-free extracts: Requirement for dATP and cytochrome c. Cell 86: 147-157
26. Martin SJ and Green DR (1995) Protease activation during apoptosis: death by a thousand cuts? Cell 82: 349-352
27. Monaghan P, Robertson D, Amos TAS, Dyer MJS, Mason DY and Greaves MF (1992) Ultrastructural localization of Bcl-2 protein. J. Histochem. Cytochem. 40: 1819-1825
28. Nagata S (1997) Apoptosis by death factor. Cell 88: 1-20
29. Nicotera P and Leist M (1997) Energy supply and the shape of death in neurons and lymphoid cells. Cell Death and Differ. 4: 435-442
30. Shimizu S, Eguchi Y, Kosaka H, Kamiike W, Matsuda H and Tsujimoto Y (1995) Prevention of hypoxia-induced cell death by Bcl-2 and Bcl-xL. Nature 374: 811-813