Inhibition of poly(adenosine diphosphate-ribose) polymerase (PARP) in experimental models of neurologic diseases: Cell death prevention

Retina

Volumn 25, Issue 8 SUPPL., 2005, Pages

  Dawson, Valina L ^a,b,c  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Departments of Physiology and Neuroscience   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; ENZYME INHIBITOR; NEUROPROTECTIVE AGENT;

APOPTOSIS; BRAIN ISCHEMIA; CELL DEATH; CELL SURVIVAL; CONFERENCE PAPER; DIABETIC NEUROPATHY; DIABETIC RETINOPATHY; DRUG ACTIVITY; ENZYME INHIBITION; INTOXICATION; KNOCKOUT MOUSE; MULTIPLE SCLEROSIS; NERVE TRANSECTION; NEUROLOGIC DISEASE; NEUROPROTECTION; NONHUMAN; OPTIC NERVE DISEASE; PARKINSON DISEASE; REPERFUSION INJURY; STROKE; TRAUMATIC BRAIN INJURY; ANIMAL; DISEASE MODEL; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; HUMAN; NECROSIS; PATHOLOGY; REVIEW;

ANIMALS; APOPTOSIS; CELL SURVIVAL; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; HUMANS; NECROSIS; NERVOUS SYSTEM DISEASES; NEUROPROTECTIVE AGENTS; POLY(ADP-RIBOSE) POLYMERASES;

EID: 33644875285     PISSN: 0275004X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00006982-200512001-00012     Document Type: Conference Paper

References (2)

1. Chang P, Jacobson MK, Mitchison TJ. Poly(ADP-ribose) is required for spindle assembly and structure. Nature 2004;432:645-649.
2. Crocker IP, Kenny LC, Thornton WA, et al. Excessive stimulation of poly(ADP-ribosyl)ation contributes to endothelial dysfunction in pre-eclampsia. Br J Pharmacol 2005;144:772-780.