Pharmacokinetic/pharmacodynamic modelling in diabetes mellitus

Clinical Pharmacokinetics

Volumn 47, Issue 7, 2008, Pages 417-448

  Landersdorfer, Cornelia B ^a   Jusko, William J ^a  

^a UNIVERSITY AT BUFFALO   (United States)

Author keywords

Alpha glucosidase inhibitors, pharmacodynamics; Antihyperglycaemics, pharmacodynamics; Biomarkers; Carbohydrate metabolism; CD26 antigen antagonists, pharmacodynamics; Diabetes mellitus; Diagnostic Tests

Indexed keywords

ALPHA GLUCOSIDASE INHIBITOR; AMYLIN; ANTIDIABETIC AGENT; DIPEPTIDYL PEPTIDASE IV INHIBITOR; EXENDIN 4; GLIBENCLAMIDE; GLICLAZIDE; GLIMEPIRIDE; GLUCAGON LIKE PEPTIDE 1; GLUCOSE; GLUCOSE TRANSPORTER 4; GLYCEROL; GLYCOGEN; INSULIN; INSULIN SENSITIZING AGENT; LEPTIN; LIRAGLUTIDE; MEGLITINIDE; METFORMIN; NATEGLINIDE; PIOGLITAZONE; PRAMLINTIDE; REPAGLINIDE; ROSIGLITAZONE; SITAGLIPTIN; SULFONYLUREA; TOLBUTAMIDE; TRIACYLGLYCEROL; UNINDEXED DRUG; VILDAGLIPTIN;

DIAGNOSTIC TEST; DISEASE COURSE; DRUG EFFECT; DRUG MECHANISM; GLUCONEOGENESIS; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; GLUCOSE INFUSION; GLYCEROL BLOOD LEVEL; GLYCOGEN LIVER LEVEL; GLYCOGENOLYSIS; HEALTH CARE COST; HORMONAL REGULATION; HUMAN; HYPERGLYCEMIA; INSULIN DEFICIENCY; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN INFUSION; INSULIN RELEASE; INSULIN TREATMENT; INTRAVENOUS GLUCOSE TOLERANCE TEST; MATHEMATICAL MODEL; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET BETA CELL; PHARMACODYNAMICS; PHARMACOKINETICS; PRIORITY JOURNAL; REVIEW; TRIACYLGLYCEROL BLOOD LEVEL;

ANIMALS; BIOLOGICAL MARKERS; BLOOD GLUCOSE; DIABETES MELLITUS; DISEASE PROGRESSION; HUMANS; HYPOGLYCEMIC AGENTS; INSULIN; MODELS, STATISTICAL;

EID: 45549108317     PISSN: 03125963     EISSN: 03125963     Source Type: Journal    
DOI: 10.2165/00003088-200847070-00001     Document Type: Review

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