메뉴 건너뛰기




Volumn 22, Issue 7, 2005, Pages 1038-1049

Disease system analysis: Basic disease progression models in degenerative disease

Author keywords

Biomarkers; Clinical endpoints; Disease progression analysis; Disease system analysis; Indirect response model

Indexed keywords

BIOLOGICAL MARKER;

EID: 23744516690     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-005-5641-5     Document Type: Article
Times cited : (72)

References (52)
  • 1
    • 0031003468 scopus 로고    scopus 로고
    • Learning versus confirming in clinical drug development
    • L. B. Sheiner. 1997 Learning versus confirming in clinical drug development Clin. Pharmacol. Ther. 61 275 291
    • (1997) Clin. Pharmacol. Ther. , vol.61 , pp. 275-291
    • Sheiner., L.B.1
  • 2
    • 0030429755 scopus 로고    scopus 로고
    • Characterization of four basic models of indirect pharmacodynamic responses
    • A. Sharma W. J. Jusko. 1996 Characterization of four basic models of indirect pharmacodynamic responses J. Pharmacokinet. Biopharm. 24 611 635
    • (1996) J. Pharmacokinet. Biopharm. , vol.24 , pp. 611-635
    • Sharma, A.1    Jusko., W.J.2
  • 4
    • 0027769745 scopus 로고
    • Comparison of four basic models of indirect pharmacodynamic responses
    • N. L. Dayneka V. Garg W. J. Jusko. 1993 Comparison of four basic models of indirect pharmacodynamic responses J. Pharmacokinet. Biopharm. 21 457 478
    • (1993) J. Pharmacokinet. Biopharm. , vol.21 , pp. 457-478
    • Dayneka, N.L.1    Garg, V.2    Jusko., W.J.3
  • 5
    • 0027943266 scopus 로고
    • Physiologic indirect response models characterize diverse types of pharmacodynamic effects
    • W. J. Jusko H. C. Ko. 1994 Physiologic indirect response models characterize diverse types of pharmacodynamic effects Clin. Pharmacol. Ther. 56 406 419
    • (1994) Clin. Pharmacol. Ther. , vol.56 , pp. 406-419
    • Jusko, W.J.1    Ko., H.C.2
  • 6
    • 0030842321 scopus 로고    scopus 로고
    • Analysis of drug-receptor interactions in vivo: A new approach in pharmacokinetic-pharmacodynamic modelling
    • P. H. Van der Graaf M. Danhof. 1997 Analysis of drug-receptor interactions in vivo: a new approach in pharmacokinetic-pharmacodynamic modelling Int. J. Clin. Pharmacol. Ther. 35 442 446
    • (1997) Int. J. Clin. Pharmacol. Ther. , vol.35 , pp. 442-446
    • Van Der Graaf, P.H.1    Danhof., M.2
  • 7
    • 0030830382 scopus 로고    scopus 로고
    • Mechanism-based pharmacokinetic-pharmacodynamic modeling of the effects of N6-cyclopentyladenosine analogs on heart rate in rat: Estimation of in vivo operational affinity and efficacy at adenosine A1 receptors
    • P. H. Van Der Graaf E. A. Van Schaick R. A. Math-ot A. P. Ijzerman M. Danhof. 1997 Mechanism-based pharmacokinetic-pharmacodynamic modeling of the effects of N6-cyclopentyladenosine analogs on heart rate in rat: estimation of in vivo operational affinity and efficacy at adenosine A1 receptors J.Pharmacol. Exp. Ther. 283 809 816
    • (1997) J.Pharmacol. Exp. Ther. , vol.283 , pp. 809-816
    • Van Der Graaf, P.H.1    Van Schaick, E.A.2    Math-Ot, R.A.3    Ijzerman, A.P.4    Danhof., M.5
  • 8
    • 0032789519 scopus 로고    scopus 로고
    • Mechanism-based pharmacokinetic-pharmacodynamic modeling of antilipolytic effects of adenosine A(1) receptor agonists in rats: Prediction of tissue-dependent efficacy in vivo
    • P. H. Van der Graaf E. A. Van Schaick S. A. Visser H. J. De De Greef A. P. Ijzerman M. Danhof. 1999 Mechanism-based pharmacokinetic-pharmacodynamic modeling of antilipolytic effects of adenosine A(1) receptor agonists in rats: prediction of tissue-dependent efficacy in vivo J. Pharmacol. Exp. Ther. 290 702 709
    • (1999) J. Pharmacol. Exp. Ther. , vol.290 , pp. 702-709
    • Van Der Graaf, P.H.1    Van Schaick, E.A.2    Visser, S.A.3    De De Greef, H.J.4    Ijzerman, A.P.5    Danhof., M.6
  • 10
    • 0036721222 scopus 로고    scopus 로고
    • Mechanism-based pharmacokinetic-pharmacodynamic modeling of concentration-dependent hysteresis and biphasic electroencephalogram effects of alphaxalone in rats
    • S. A. Visser C. J. Smulders B. P. Reijers P. H. Van der Graaf L. A. Peletier M. Danhof. 2002 Mechanism-based pharmacokinetic-pharmacodynamic modeling of concentration-dependent hysteresis and biphasic electroencephalogram effects of alphaxalone in rats J. Pharmacol. Exp. Ther. 302 1158 1167
    • (2002) J. Pharmacol. Exp. Ther. , vol.302 , pp. 1158-1167
    • Visser, S.A.1    Smulders, C.J.2    Reijers, B.P.3    Van Der Graaf, P.H.4    Peletier, L.A.5    Danhof., M.6
  • 12
    • 0036137066 scopus 로고    scopus 로고
    • A competitive interaction model predicts the effect of WAY-100,635 on the time course of R-(+)-8-hydroxy-2-(di-n-propylamino)tetralin-induced hypothermia
    • K. P. Zuideveld N. Treijtel H. J. Maas J. M. Gubbens-Stibbe L. A. Peletier P. H. van Der Graaf M. Danhof. 2002 A competitive interaction model predicts the effect of WAY-100,635 on the time course of R-(+)-8-hydroxy-2-(di- n-propylamino)tetralin-induced hypothermia J. Pharmacol. Exp. Ther. 300 330 338
    • (2002) J. Pharmacol. Exp. Ther. , vol.300 , pp. 330-338
    • Zuideveld, K.P.1    Treijtel, N.2    Maas, H.J.3    Gubbens-Stibbe, J.M.4    Peletier, L.A.5    Van Der Graaf, P.H.6    Danhof., M.7
  • 14
    • 0028141439 scopus 로고
    • The effect of tacrine and lecithin in Alzheimer's disease. a population pharmacodynamic analysis of five clinical trials
    • N. H. Holford K. Peace. 1994 The effect of tacrine and lecithin in Alzheimer's disease. A population pharmacodynamic analysis of five clinical trials Eur. J. Clin. Pharmacol. 47 17 23
    • (1994) Eur. J. Clin. Pharmacol. , vol.47 , pp. 17-23
    • Holford, N.H.1    Peace., K.2
  • 15
    • 0026452038 scopus 로고
    • Methodologic aspects of a population pharmacodynamic model for cognitive effects in Alzheimer patients treated with tacrine
    • N. H. Holford K. Peace. 1992 Methodologic aspects of a population pharmacodynamic model for cognitive effects in Alzheimer patients treated with tacrine Proc. Natl. Acad. Sci. USA 89 11466 11470
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 11466-11470
    • Holford, N.H.1    Peace., K.2
  • 16
    • 0026471544 scopus 로고
    • Results and validation of a population pharmacodynamic model for cognitive effects in Alzheimer patients treated with tacrine
    • N. H. Holford K. E. Peace. 1992 Results and validation of a population pharmacodynamic model for cognitive effects in Alzheimer patients treated with tacrine Proc. Natl. Acad. Sci. USA 89 11471 11475
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 11471-11475
    • Holford, N.H.1    Peace., K.E.2
  • 17
    • 33645182348 scopus 로고    scopus 로고
    • Understanding disease progression using clinical pharmacology
    • M. Danhof, M. Karlsson, and R. J. Powell (eds.) Leiden/Amsterdam Center for Drug Research, Leiden. Advances in Simultaneous Pharmacokinetic/ Pharmacodynamic Modelling, 4th International Symposium, 24-27 April, Noordwijkerhout
    • N. H. G. Holford. Understanding disease progression using clinical pharmacology. In M. Danhof, M. Karlsson, and R. J. Powell (eds.), Measurement and Kinetics of in vivo Drug Effects, Leiden/Amsterdam Center for Drug Research, Leiden. Advances in Simultaneous Pharmacokinetic/Pharmacodynamic Modelling, 4th International Symposium, 24-27 April, Noordwijkerhout, 2002.
    • (2002) Measurement and Kinetics of in Vivo Drug Effects
    • Holford, N.H.G.1
  • 19
    • 0035037328 scopus 로고    scopus 로고
    • Use of biomarkers and surrogate endpoints in drug development and regulatory decision making: Criteria, validation, strategies
    • L. J. Lesko A. J. Atkinson Jr. Jr 2001 Use of biomarkers and surrogate endpoints in drug development and regulatory decision making: criteria, validation, strategies Annu. Rev. Pharmacol. Toxicol. 41 347 366
    • (2001) Annu. Rev. Pharmacol. Toxicol. , vol.41 , pp. 347-366
    • Lesko, L.J.1    Atkinson Jr., A.J.2
  • 20
    • 0037380673 scopus 로고    scopus 로고
    • Biomarkers in drug discovery and development: From target identification through drug marketing
    • W. A. Colburn. 2003 Biomarkers in drug discovery and development: from target identification through drug marketing J. Clin. Pharmacol. 43 329 341
    • (2003) J. Clin. Pharmacol. , vol.43 , pp. 329-341
    • Colburn., W.A.1
  • 21
    • 0141762330 scopus 로고    scopus 로고
    • Biomarkers, validation and pharmacokinetic-pharmacodynamic modelling
    • W. A. Colburn J. W. Lee. 2003 Biomarkers, validation and pharmacokinetic-pharmacodynamic modelling Clin. Pharmacokinet. 42 997 1022
    • (2003) Clin. Pharmacokinet. , vol.42 , pp. 997-1022
    • Colburn, W.A.1    Lee., J.W.2
  • 23
    • 3342964033 scopus 로고    scopus 로고
    • Biomarker discovery and validation: Technologies and integrative approaches
    • S. E. Ilyin S. M. Belkowski C. R. Plata-Salaman. 2004 Biomarker discovery and validation: technologies and integrative approaches Trends Biotechnol. 22 411 416
    • (2004) Trends Biotechnol. , vol.22 , pp. 411-416
    • Ilyin, S.E.1    Belkowski, S.M.2    Plata-Salaman., C.R.3
  • 24
    • 0034491130 scopus 로고    scopus 로고
    • Optimizing the science of drug development: Opportunities for better candidate selection and accelerated evaluation in humans
    • L. J. Lesko M. Rowland C. C. Peck T. F. Blaschke. 2000 Optimizing the science of drug development: opportunities for better candidate selection and accelerated evaluation in humans Pharm. Res. 17 1335 1344
    • (2000) Pharm. Res. , vol.17 , pp. 1335-1344
    • Lesko, L.J.1    Rowland, M.2    Peck, C.C.3    Blaschke., T.F.4
  • 25
    • 0032898755 scopus 로고    scopus 로고
    • Prospective six year follow up of patients withdrawn from a randomised study comparing parenteral gold salt and methotrexate
    • O. Sander G. Herborn E. Bock R. Rau. 1999 Prospective six year follow up of patients withdrawn from a randomised study comparing parenteral gold salt and methotrexate Ann. Rheum. Dis. 58 281 287
    • (1999) Ann. Rheum. Dis. , vol.58 , pp. 281-287
    • Sander, O.1    Herborn, G.2    Bock, E.3    Rau., R.4
  • 27
    • 0242335593 scopus 로고    scopus 로고
    • Serum cartilage oligomeric matrix protein (COMP) decreases in rheumatoid arthritis patients treated with infliximab or etanercept
    • M. Crnkic B. Mansson L. Larsson P. Geborek D. Heinegard T. Saxne. 2003 Serum cartilage oligomeric matrix protein (COMP) decreases in rheumatoid arthritis patients treated with infliximab or etanercept Arthritis Res. Ther. 5 R181 R185
    • (2003) Arthritis Res. Ther. , vol.5
    • Crnkic, M.1    Mansson, B.2    Larsson, L.3    Geborek, P.4    Heinegard, D.5    Saxne., T.6
  • 29
    • 33645180424 scopus 로고    scopus 로고
    • Disease progression in Parkinson's disease - Evidence for protective effects of drug treatment
    • Uppsala, Sweden
    • N. H. Holford, P. L. Chan, and J. Nutt. Disease progression in Parkinson's disease-evidence for protective effects of drug treatment. 13th Population Approach Group Conference, Uppsala, Sweden, http://www.page-meeting. org, 2004.
    • (2004) 13th Population Approach Group Conference
    • Holford, N.H.1    Chan, P.L.2    Nutt, J.3
  • 30
    • 0030696346 scopus 로고    scopus 로고
    • Combination of sulphasalazine and methotrexate versus the single components in early rheumatoid arthritis: A randomized, controlled, double-blind, 52 week clinical trial
    • C. J. Haagsma P. L. van Riel A. J. de Jong L. B. van de Putte 1997 Combination of sulphasalazine and methotrexate versus the single components in early rheumatoid arthritis: a randomized, controlled, double-blind, 52 week clinical trial Br. J. Rheumatol. 36 1082 1088
    • (1997) Br. J. Rheumatol. , vol.36 , pp. 1082-1088
    • Haagsma, C.J.1    Van Riel, P.L.2    De Jong, A.J.3    Van De Putte, L.B.4
  • 31
    • 0036913449 scopus 로고    scopus 로고
    • More efficient clinical trials through use of scientific model-based statistical tests
    • E. N. Jonsson L. B. Sheiner. 2002 More efficient clinical trials through use of scientific model-based statistical tests Clin. Pharmacol. Ther. 72 603 614
    • (2002) Clin. Pharmacol. Ther. , vol.72 , pp. 603-614
    • Jonsson, E.N.1    Sheiner., L.B.2
  • 32
    • 0036039781 scopus 로고    scopus 로고
    • Is intent-to-treat analysis always (ever) enough?
    • L. B. Sheiner. 2002 Is intent-to-treat analysis always (ever) enough? Br. J. Clin. Pharmacol. 54 203 211
    • (2002) Br. J. Clin. Pharmacol. , vol.54 , pp. 203-211
    • Sheiner., L.B.1
  • 33
    • 0028817457 scopus 로고
    • Intention-to-treat analysis and the goals of clinical trials
    • L. B. Sheiner D. B. Rubin. 1995 Intention-to-treat analysis and the goals of clinical trials Clin. Pharmacol. Ther. 57 6 15
    • (1995) Clin. Pharmacol. Ther. , vol.57 , pp. 6-15
    • Sheiner, L.B.1    Rubin., D.B.2
  • 34
    • 0037036227 scopus 로고    scopus 로고
    • Pharmacokinetic-pharmacodynamic modelling of the hypothermic and corticosterone effects of the 5-HT1A receptor agonist flesinoxan
    • K. P. Zuideveld A. van Gestel L. A. Peletier P. H. Van der Graaf M. Danhof. 2002 Pharmacokinetic-pharmacodynamic modelling of the hypothermic and corticosterone effects of the 5-HT1A receptor agonist flesinoxan Eur. J. Pharmacol. 445 43 54
    • (2002) Eur. J. Pharmacol. , vol.445 , pp. 43-54
    • Zuideveld, K.P.1    Van Gestel, A.2    Peletier, L.A.3    Van Der Graaf, P.H.4    Danhof., M.5
  • 35
    • 0037327319 scopus 로고    scopus 로고
    • Population PKPD modelling of the long-term hypoglycaemic effect of gliclazide given as a once-a-day modified release (MR) formulation
    • N. Frey C. Laveille M. Paraire M. Francillard N. H. Holford R. Jochemsen. 2003 Population PKPD modelling of the long-term hypoglycaemic effect of gliclazide given as a once-a-day modified release (MR) formulation Br. J. Clin. Pharmacol. 55 147 157
    • (2003) Br. J. Clin. Pharmacol. , vol.55 , pp. 147-157
    • Frey, N.1    Laveille, C.2    Paraire, M.3    Francillard, M.4    Holford, N.H.5    Jochemsen., R.6
  • 36
    • 1542327580 scopus 로고    scopus 로고
    • Dopamine agonists, receptor selectivity and dyskinesia induction in Parkinson's disease
    • P. Jenner. 2003 Dopamine agonists, receptor selectivity and dyskinesia induction in Parkinson's disease Curr. Opin. Neurol. 16 S3 S7
    • (2003) Curr. Opin. Neurol. , vol.16
    • Jenner., P.1
  • 37
    • 1842856723 scopus 로고    scopus 로고
    • Pharmacology of dopamine agonists in the treatment of Parkinson's disease
    • P. Jenner. 2002 Pharmacology of dopamine agonists in the treatment of Parkinson's disease Neurology 58 S1 S8
    • (2002) Neurology , vol.58
    • Jenner., P.1
  • 38
    • 0037202792 scopus 로고    scopus 로고
    • Dopamine agonist monotherapy in Parkinson's disease
    • C. E. Clarke M. Guttman. 2002 Dopamine agonist monotherapy in Parkinson's disease Lancet 360 1767 1769
    • (2002) Lancet , vol.360 , pp. 1767-1769
    • Clarke, C.E.1    Guttman., M.2
  • 39
    • 2442570592 scopus 로고    scopus 로고
    • Disease modification in Parkinson's disease
    • A. H. Schapira. 2004 Disease modification in Parkinson's disease Lancet Neurol. 3 362 368
    • (2004) Lancet Neurol. , vol.3 , pp. 362-368
    • Schapira., A.H.1
  • 41
  • 42
    • 1542269162 scopus 로고    scopus 로고
    • The scientific basis for the current treatment of Parkinson's disease
    • C. W. Olanow. 2004 The scientific basis for the current treatment of Parkinson's disease Annu. Rev. Med. 55 41 60
    • (2004) Annu. Rev. Med. , vol.55 , pp. 41-60
    • Olanow., C.W.1
  • 44
    • 10844265575 scopus 로고    scopus 로고
    • A semimechanistic and mechanistic population PK-PD model for biomarker response to ibandronate, a new bisphosphonate for the treatment of osteoporosis
    • G. Pillai R. Gieschke T. Goggin P. Jacqmin R. C. Schimmer J. L. Steimer. 2004 A semimechanistic and mechanistic population PK-PD model for biomarker response to ibandronate, a new bisphosphonate for the treatment of osteoporosis Br. J. Clin. Pharmacol. 58 618 631
    • (2004) Br. J. Clin. Pharmacol. , vol.58 , pp. 618-631
    • Pillai, G.1    Gieschke, R.2    Goggin, T.3    Jacqmin, P.4    Schimmer, R.C.5    Steimer., J.L.6
  • 46
    • 0842267170 scopus 로고    scopus 로고
    • Structure-modifying agents for osteoarthritis: An update
    • P. Richette T. Bardin. 2004 Structure-modifying agents for osteoarthritis: an update Jt. Bone Spine 71 18 23
    • (2004) Jt. Bone Spine , vol.71 , pp. 18-23
    • Richette, P.1    Bardin., T.2
  • 47
    • 33645180987 scopus 로고    scopus 로고
    • Pioglitazone efficacy in NIDDM (diabetes type II) therapy: Unification of two glycemic control markers by a cascading disease progression model
    • M. Danhof, M. Karlsson, and R. J. Powell (eds.) Leiden/Amsterdam Center for Drug Research, Leiden. Advances in Simultaneous Pharmacokinetic/ Pharmacodynamic Modelling, 4th International Symposium, 24-27 April, Noordwijkerhout
    • J. DeJongh, D. Eckland, R. J. Heine, and M. Danhof. Pioglitazone efficacy in NIDDM (diabetes type II) therapy: unification of two glycemic control markers by a cascading disease progression model. In M. Danhof, M. Karlsson, and R. J. Powell (eds.), Measurement and Kinetics of in vivo Drug Effects, Leiden/Amsterdam Center for Drug Research, Leiden. Advances in Simultaneous Pharmacokinetic/Pharmacodynamic Modelling, 4th International Symposium, 24-27 April, Noordwijkerhout, 2002.
    • (2002) Measurement and Kinetics of in Vivo Drug Effects
    • Dejongh, J.1    Eckland, D.2    Heine, R.J.3    Danhof, M.4
  • 49
    • 33645181101 scopus 로고    scopus 로고
    • Disease progression modelling; Application of population analysis to distinguish between symptomatic and protective treatment effects
    • Verona, Italy
    • W. DeWinter, J. DeJongh, B. Ploeger, R. Urquhart, I. Moules, D. Eckland, and M. Danhof. Disease progression modelling; application of population analysis to distinguish between symptomatic and protective treatment effects. 12th Population Approach Group Conference, Verona, Italy, http://www.page-meeting. org, 2003.
    • (2003) 12th Population Approach Group Conference
    • Dewinter, W.1    Dejongh, J.2    Ploeger, B.3    Urquhart, R.4    Moules, I.5    Eckland, D.6    Danhof, M.7
  • 51
    • 0037403960 scopus 로고    scopus 로고
    • Diversity of mechanism-based pharmacodynamic models
    • D. E. Mager E. Wyska W. J. Jusko. 2003 Diversity of mechanism-based pharmacodynamic models Drug Metab. Dispos. 31 510 518
    • (2003) Drug Metab. Dispos. , vol.31 , pp. 510-518
    • Mager, D.E.1    Wyska, E.2    Jusko., W.J.3
  • 52
    • 0031890386 scopus 로고    scopus 로고
    • Characteristics of indirect pharmacodynamic models and applications to clinical drug responses
    • A. Sharma W. J. Jusko. 1998 Characteristics of indirect pharmacodynamic models and applications to clinical drug responses Br. J. Clin. Pharmacol. 45 229 239
    • (1998) Br. J. Clin. Pharmacol. , vol.45 , pp. 229-239
    • Sharma, A.1    Jusko., W.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.