Insulin secretion rates estimated by two mathematical methods in pancreas-kidney transplant recipients

American Journal of Physiology - Endocrinology and Metabolism

Volumn 274, Issue 4 37-4, 1998, Pages

  Christiansen, Erik ^a   Kjems, Lise L ^c   Vølund, Aage ^b   Tibell, Annika ^d   Binder, Christian ^a   Madsbad, Sten ^c  

^a STENO DIABETES CENTER   (Denmark)

^b NOVO NORDISK A S   (Denmark)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

^d KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Glucagon test; Kidney transplantation C peptide; Kinetics; Oral glucose tolerance test; Pancreas kidney transplantation

Indexed keywords

C PEPTIDE; GLUCAGON; GLUCOSE; INSULIN;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HYPERINSULINEMIA; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN RELEASE; KIDNEY TRANSPLANTATION; MALE; MATHEMATICAL MODEL; ORAL GLUCOSE TOLERANCE TEST; PANCREAS TRANSPLANTATION; PRIORITY JOURNAL; RECIPIENT;

EID: 0031968524     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.1998.274.4.e716     Document Type: Article

References (30)

1. Andersen, L., B. Dinesen, P. N. Jørgensen, F. Poulsen, and M. E. Røder. Enzyme immunoassay of intact insulin in serum and plasma. Clin. Chem. 39: 578-582, 1993.
2. Blackman, J. D., K. S. Polonsky, J. B. Jaspan, J. Sturis, E. Van Cauter, and R. J. Thistlethwaite, Jr. Insulin secretory profiles and C-peptide clearance kinetics at 6 months and 2 years after kidney-pancreas transplantation. Diabetes 41: 1346-1354, 1992.
3. Christiansen, E., H. B. Andersen, K. Rasmussen, N. J. Christensen, K. Olgaard, P. Kirkegaard, B. Tronier, A. Vølund, P. Damsbo, F. Burcharth, and S. Madsbad. Pancreatic β-cell function and glucose metabolism in human pancreas and kidney transplantation. Am. J. Physiol. 264 (Endocrinol. Metab. 27): E441-E449, 1993.
4. Christiansen, E., A. Tibell, C. G. Groth, K. Rasmussen, O. Pedersen, F. Burcharth, N. J. Christensen, A. Vølund, and S. Madsbad. Limitations in the use of insulin or C-peptide alone in the assessment of β-cell function in pancreas transplant recipients. Transplant. Proc. 26: 467-468, 1994.
5. Christiansen, E., A. Tibell., S. Madsbad, K. Rasmussen, and G. Tydén. Defects in quantitative and qualitative β-cell function following successful segmental pancreas transplantation. Transplant. Proc. 25: 1186-1189, 1993.
6. Christiansen, E., A. Tibell, A. Vølund, J. J. Holst, K. Rasmussen, L. Schäffer, and S. Madsbad. Metabolism of oral glucose in pancreas transplant recipients with normal and impaired glucose tolerance. J. Clin. Endocrinol Metab. 82: 2299-2307, 1997.
7. Christiansen, E., A. Tibell, A. Vølund, K. Rasmussen, C. G. Groth, J. J. Holst, O. Pedersen, N. J. Christensen, and S. Madsbad. Pancreatic endocrine function in recipients of segmental and whole pancreas transplantation. J. Clin. Endocrinol. Metab. 81: 3972-3979, 1996.
8. Christiansen, E., A. Tibell, A. Vølund, K. Rasmussen, G. Tydén, O. Pedersen, N. J. Christensen, and S. Madsbad. Insulin secretion, insulin action and non-insulin-dependent glucose uptake in pancreas transplant recipients. J. Clin. Endocrinol. Metab. 79: 1561-1569, 1994.
9. Christiansen, E., H. Vestergaard, A. Tibell, O. Hother Nielsen, J. J. Holst, O. Pedersen, and S. Madsbad. Impaired insulin-stimulated nonoxidative glucose metabolism in pancreaskidney transplant recipients. Dose-response effects of insulin on glucose turnover. Diabetes 45: 1267-1275, 1996.
10. Diem, P., M. Abid, J. B. Redmon, D. E. R. Sutherland, and R. P. Robertson. Systemic venous drainage of pancreas allografts as independent cause of hyperinsulinemia in type 1 diabetic recipients. Diabetes 39: 534-540, 1990.
11. Eaton, R. P., R. C. Allen, D. S. Schade, K. M. Erickson, and J. Standefer. Prehepatic insulin production in man: kinetic analysis using peripheral connecting peptide behavior. J. Endocrinol. Metab. 51: 520-528, 1980.
12. Heding, L. G. Specific and direct radioimmunoassay for human C-peptide in serum. Diabetologia 11: 547-548, 1975.
13. Katz, H., M. Homan, J. Velosa, R. P. Robertson, and R. Rizza. Effects of pancreas transplantation on postprandial glucose metabolism. N. Engl. J. Med. 325: 1278-1283, 1991.
14. Kjems, L., E. Christiansen, A. Vølund, and S. Madshad. Valid single-day method for calculation on insulin secretion in normal and NIDDM subjects (Abstract). Diabetologia 39, Suppl. 1: 160A, 1996.
15. Luzi, L., A. Secchi, F. Facchini, A. Battezzati, C. Staudacher, D. Spotti, R. Castoldi, G. Ferrari, V. Di Carlo, and G. Pozza. Reduction of insulin resistance by combined kidney-pancreas transplantation in type 1 (insulin-dependent) diabetic patients. Diabetologia 33: 549-556, 1990.
16. Madsbad, S., S. G. Hartling, and O. K. Faber. C-peptide and proinsulin. In: International Textbook in Diabetes Mellitus, edited by K G. M. M. Alberti, R. A. DeFronzo, H. Keen, and P. Zimmet. New York: Wiley, 1992, p. 303-332.
17. Osei, K., M. L. Henry, T. M. O'Dorisio, R. J. Tesi, B. G. Sommer, and R. M. Ferguson. Physiological and pharmacological stimulation of pancreatic islet hormone secretion in type 1 diabetic pancreas allograft recipients. Diabetes 39: 1235-1242, 1990.
18. Pagano, G., P. Cavallo-Perin, B. Cassader, A. Bruno, A. Ozzello, and P. Masciola. An in vivo and in vitro study of the mechanism of prednisone-induced insulin resistance in healthy subjects. J. Clin. Invest. 72: 1814-1820, 1983.
19. Pfeffer, F., M. A. Nauck, S. Benz, A. Gwodzinski, R. Zink, M. Büsing, H. D. Becker, and U. T. Hopt. Determinants of a normal (versus impaired) oral glucose tolerance after combined pancreas-kidney transplantation in IDDM. Diabetologia 39: 462-468, 1996.
20. Polonsky, K. S., B. Frank, W. Pugh, A. Addis, T. Karrison, P. Meier, H. Tager, and A. Rubenstein. The limitations to and valid use of C-peptide as a marker of the secretion of insulin. Diabetes 35: 379-386, 1986.
21. Polonsky, K. S., J. Licinio-Paixao, B. D. Given, W. Pugh, P. Rue, J. Galloway, T. Karrison, and B. Frank. Use of biosynthetic human C-peptide in the measurements of insulin secretion rates in normal volunteers and type 1 diabetic patients. J. Clin. Invest. 77: 98-105, 1986.
22. Polonsky, K. S., and A. Rubenstein. C-peptide as a measure of the secretion and hepatic extraction of insulin. Pitfalls and limitations. Diabetes 33: 486-494, 1984.
23. Radziuk, J., and T. Morishima. Assessment of insulin kinetics in vivo. In: Methods in Diabetes Research. Clinical Methods, edited by W. L. Clark, J. Larner, and S. L. Pohl. New York: Wiley, 1985 p. 91-106.
24. Rudenski, A. S., J. P. Hosker, M. A. Burnett, D. R. Matthews, and R. C. Turner. The beta cell glucose stimulus-response curve in normal humans assessed by insulin and C-peptide secretion rates. Metabolism 37: 526-534, 1988.
25. Teuscher, A. U., E. R. Seaquist, and R. P. Robertson. Diminished insulin secretory reserve in diabetic pancreas transplant and nondiabetic kidney transplant recipients. Diabetes 43: 593-598, 1994.
26. Van Cauter E., F. Mestrez, J. Sturis, and K. S. Polonsky. Estimation of insulin secretion rates from C-peptide levels. Comparison of individual and standard kinetic parameters for C-peptide clearance. Diabetes 41: 368-377, 1992.
27. Vora, J., D. R. Owens, S. Luzio, J. Atiea, R. Ryder, and T. M. Hayes. Renal responses to intravenous somatostatin in insulin-dependent diabetic patients and normal subjects. J. Clin. Endocrinol. Metab. 64: 975-979, 1987.
28. Vølund, A., K. S. Polonsky, and R. N. Bergman. Calculated pattern of intraportal insulin appearance without independent assessment of C-peptide kinetics. Diabetes 36: 1195-1202, 1987.
29. Walton, C., I. F. Godsland, A. J. Proudler, C. Felton, and V. Wynn. Evaluation of four mathematical models of glucose and insulin dynamics with analysis of effects of age and obesity. Am. J. Physiol. 262 (Endocrinol. Metab. 25): E755-E762, 1992.
30. Yamamoto, A, S. Akazawa, Y. Yamaguchi, A. Yokota, H. Yamasaki, T. Nakanishi, D. Tahara, F. Matsuya, Y. Saito, and S. Nagataki. Effects of cyclosporin A and low dosages of steroid on posttransplant diabetes in kidney transplant recipients. Diabetes Care 14: 867-870, 1991.