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Annals of the New York Academy of Sciences
Volumn 1079, Issue , 2006, Pages 369-373
Mechanisms mediating anti-CD3 antibody efficacy: Insights from a mathematical model of type 1 diabetes
Author keywords

145 2C11; Antigen presenting cells; b cells; Diabetes remission; Glucose control; Systems biology
Indexed keywords

CD3 ANTIBODY;
EID: 33845714124     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1196/annals.1375.057     Document Type: Conference Paper
Times cited : (5)
References (8)
  • 1
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    • A single course of anti-CD3 monoclonal antibody hOKT3 {gamma} 1(Ala-Ala) results in improvement in C-peptide responses and clinical parameters for at least 2 years after onset of type 1 diabetes
    • HEROLD, K.C., S.E. GITELMAN, U. MASHARANI, et al. 2005. A single course of anti-CD3 monoclonal antibody hOKT3 {gamma} 1(Ala-Ala) results in improvement in C-peptide responses and clinical parameters for at least 2 years after onset of type 1 diabetes. Diabetes 54: 1763-1769.
    • (2005) Diabetes , vol.54 , pp. 1763-1769
    • Herold, K.C.1    Gitelman, S.E.2    Masharani, U.3
  • 2
    • 20544443927 scopus 로고    scopus 로고
    • Insulin needs after CD3-antibody therapy in new-onset type 1 diabetes
    • KEYMEULEN, B., E. VANDEMEULEBROUCKE, A.G. ZIEGLER, et al. 2005. Insulin needs after CD3-antibody therapy in new-onset type 1 diabetes. N. Engl. J. Med. 352: 2598-2608.
    • (2005) N. Engl. J. Med. , vol.352 , pp. 2598-2608
    • Keymeulen, B.1    Vandemeulebroucke, E.2    Ziegler, A.G.3
  • 3
    • 0141796312 scopus 로고    scopus 로고
    • TGF-beta-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes
    • BELGHITH, M., J.A. BLUESTONE, S. BARRIOT, et al. 2003. TGF-beta-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes. Nat. Med. 9: 1202-1208.
    • (2003) Nat. Med. , vol.9 , pp. 1202-1208
    • Belghith, M.1    Bluestone, J.A.2    Barriot, S.3
  • 4
    • 0024457594 scopus 로고
    • Neonatal injection of CD3 antibody into nonobese diabetic mice reduces the incidence of insulitis and diabetes
    • HAYWARD, A.R. & M. SHREIBER. 1989. Neonatal injection of CD3 antibody into nonobese diabetic mice reduces the incidence of insulitis and diabetes. J. Immunol. 143: 1555-1559.
    • (1989) J. Immunol. , vol.143 , pp. 1555-1559
    • Hayward, A.R.1    Shreiber, M.2
  • 5
    • 23844525846 scopus 로고    scopus 로고
    • A comprehensive review of interventions in the NOD mouse and implications for translation
    • SHODA, L.K., D.L. YOUNG, S. RAMANUJAN, et al. 2005. A comprehensive review of interventions in the NOD mouse and implications for translation. Immunity 23: 115-126.
    • (2005) Immunity , vol.23 , pp. 115-126
    • Shoda, L.K.1    Young, D.L.2    Ramanujan, S.3
  • 6
    • 0027958044 scopus 로고
    • Anti-CD3 antibody induces long-term remission of overt autoimmunity in nonobese diabetic mice
    • CHATENOUD, L., E. THERVET, J. PRIMO & J.F. BACH. 1994. Anti-CD3 antibody induces long-term remission of overt autoimmunity in nonobese diabetic mice. Proc. Natl. Acad. Sci. USA 91: 123-127.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 123-127
    • Chatenoud, L.1    Thervet, E.2    Primo, J.3    Bach, J.F.4
  • 7
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    • CD3 antibody-induced dominant self tolerance in overtly diabetic NOD mice
    • CHATENOUD, L., J. PRIMO & J.F. BACH. 1997. CD3 antibody-induced dominant self tolerance in overtly diabetic NOD mice. J. Immunol. 158: 2947-2954.
    • (1997) J. Immunol. , vol.158 , pp. 2947-2954
    • Chatenoud, L.1    Primo, J.2    Bach, J.F.3

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.