-
1
-
-
0034816964
-
Delineating the genetic basis of systemic lupus erythematosus
-
Wakeland, E. K., Liu, K., Graham, R. R. and Behrens, T. W. 2001. Delineating the genetic basis of systemic lupus erythematosus. Immunity 15:397.
-
(2001)
Immunity
, vol.15
, pp. 397
-
-
Wakeland, E.K.1
Liu, K.2
Graham, R.R.3
Behrens, T.W.4
-
2
-
-
0034892128
-
Autoimmune disease: Why and where it occurs
-
Marrack, P., Kappler, J. and Kotzin, B. L. 2001. Autoimmune disease: why and where it occurs. Nat. Med. 7:899.
-
(2001)
Nat. Med.
, vol.7
, pp. 899
-
-
Marrack, P.1
Kappler, J.2
Kotzin, B.L.3
-
3
-
-
1842417145
-
Constitutive expression of interleukin (IL)-4 in vivo causes autoimmune-type disorders in mice
-
Erb, K. J., Ruger, B., von Brevern, M., Ryffel, B., Schimpl, A. and Rivett, K. 1997. Constitutive expression of interleukin (IL)-4 in vivo causes autoimmune-type disorders in mice. J. Exp. Med. 185:329.
-
(1997)
J. Exp. Med.
, vol.185
, pp. 329
-
-
Erb, K.J.1
Ruger, B.2
von Brevern, M.3
Ryffel, B.4
Schimpl, A.5
Rivett, K.6
-
4
-
-
0030702821
-
Antinuclear autoantibodies and lupus nephritis in transgenic mice expressing interferon gamma in the epidermis
-
Seery, J. P., Carroll, J. M., Cattell, V. and Watt, F. M. 1997. Antinuclear autoantibodies and lupus nephritis in transgenic mice expressing interferon gamma in the epidermis. J. Exp. Med. 186:1451.
-
(1997)
J. Exp. Med.
, vol.186
, pp. 1451
-
-
Seery, J.P.1
Carroll, J.M.2
Cattell, V.3
Watt, F.M.4
-
5
-
-
0033509042
-
h2 balance of peripheral T helper cells in systemic lupus erythematosus
-
h2 balance of peripheral T helper cells in systemic lupus erythematosus. Arthritis. Rheum. 42:1644.
-
(1999)
Arthritis Rheum.
, vol.42
, pp. 1644
-
-
Akahoshi, M.1
Nakashima, H.2
Tanaka, Y.3
Kohsaka, T.4
Nagano, S.5
Ohgami, E.6
Arinobu, Y.7
Yamaoka, K.8
Niiro, H.9
Shinozaki, M.10
Hirakata, H.11
Horiuchi, T.12
Otsuka, T.13
Niho, Y.14
-
6
-
-
0033938967
-
Current evidence for the induction of autoimmune rheumatic manifestations by cytokine therapy
-
Ioannou, Y. and Isenberg, D. A. 2000. Current evidence for the induction of autoimmune rheumatic manifestations by cytokine therapy. Arthritis. Rheum. 43:1431.
-
(2000)
Arthritis Rheum.
, vol.43
, pp. 1431
-
-
Ioannou, Y.1
Isenberg, D.A.2
-
8
-
-
0033213901
-
Negative regulation of cytokine signaling: STAT-induced STAT inhibitor
-
Naka, T., Fujimoto, M. and Kishimoto, T. 1999. Negative regulation of cytokine signaling: STAT-induced STAT inhibitor. Trends. Biochem. Sci. 24:394.
-
(1999)
Trends. Biochem. Sci.
, vol.24
, pp. 394
-
-
Naka, T.1
Fujimoto, M.2
Kishimoto, T.3
-
10
-
-
0034801684
-
SOCS proteins: Negative regulators of cytokine signaling
-
Krebs, D. L. and Hilton, D. J. 2001. SOCS proteins: negative regulators of cytokine signaling. Stem Cells 19:378.
-
(2001)
Stem Cells
, vol.19
, pp. 378
-
-
Krebs, D.L.1
Hilton, D.J.2
-
11
-
-
0033520467
-
SOCS1 deficiency causes a lymphocyte-dependent perinatal lethality
-
Marine, J. C., Topham, D. J., McKay, C., Wang, D., Parganas, E., Stravopodis, D., Yoshimura, A. and Ihle, J. N. 1999. SOCS1 deficiency causes a lymphocyte-dependent perinatal lethality. Cell 98:609.
-
(1999)
Cell
, vol.98
, pp. 609
-
-
Marine, J.C.1
Topham, D.J.2
McKay, C.3
Wang, D.4
Parganas, E.5
Stravopodis, D.6
Yoshimura, A.7
Ihle, J.N.8
-
12
-
-
13044276245
-
Accelerated apoptosis of lymphocytes by augmented induction of Bax in SSI-1 (STAT-induced STAT inhibitor-1) deficient mice
-
Naka, T., Matsumoto, T., Narazaki, M., Fujimoto, M., Morita, Y., Ohsawa, Y., Saito, H., Nagasawa, T., Uchiyama, Y. and Kishimoto, T. 1998. Accelerated apoptosis of lymphocytes by augmented induction of Bax in SSI-1 (STAT-induced STAT inhibitor-1) deficient mice. Proc. Natl Acad. Sci. USA 95:15577.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 15577
-
-
Naka, T.1
Matsumoto, T.2
Narazaki, M.3
Fujimoto, M.4
Morita, Y.5
Ohsawa, Y.6
Saito, H.7
Nagasawa, T.8
Uchiyama, Y.9
Kishimoto, T.10
-
13
-
-
0032564463
-
Liver degeneration and lymphoid deficiencies in mice lacking suppressor of cytokine signaling
-
Starr, R., Metcalf, D., Elefanty, A. G., Brysha, M., Willson, T. A., Nicola, N. A., Hilton, D. J. and Alexander, W. S. 1998. Liver degeneration and lymphoid deficiencies in mice lacking suppressor of cytokine signaling. Proc. Natl Acad. Sci. USA 95:14395.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 14395
-
-
Starr, R.1
Metcalf, D.2
Elefanty, A.G.3
Brysha, M.4
Willson, T.A.5
Nicola, N.A.6
Hilton, D.J.7
Alexander, W.S.8
-
14
-
-
0033520326
-
SOCS1 is a critical inhibitor of interferon gamma signaling and prevents the potentially fatal neonatal actions of this cytokine
-
Alexander, W. S., Starr, R., Fenner, J. E., Scott, C. L., Handman, E., Sprigg, N. S., Corbin, J. E., Cornish, A. L., Darwiche, R., Owczarek, C. M., Kay, T. W., Nicola, N. A., Hertzog, P. J., Metcalf, D. and Hilton, D. J. 1999. SOCS1 is a critical inhibitor of interferon gamma signaling and prevents the potentially fatal neonatal actions of this cytokine. Cell 98:597.
-
(1999)
Cell
, vol.98
, pp. 597
-
-
Alexander, W.S.1
Starr, R.2
Fenner, J.E.3
Scott, C.L.4
Handman, E.5
Sprigg, N.S.6
Corbin, J.E.7
Cornish, A.L.8
Darwiche, R.9
Owczarek, C.M.10
Kay, T.W.11
Nicola, N.A.12
Hertzog, P.J.13
Metcalf, D.14
Hilton, D.J.15
-
15
-
-
0035008978
-
SOCS-1/SSI-1 -deficient NKT cells participate in severe hepatitis through dysregulated cross-talk inhibition of IFN-gamma and IL-4 signaling in vivo
-
Naka, T., Tsutsui, H., Fujimoto, M., Kawazoe, Y., Kohzaki, H., Morita, Y., Nakagawa, R., Narazaki, M., Adachi, K., Yoshimoto, T., Nakanishi, K. and Kishimoto, T. 2001. SOCS-1/SSI-1 -deficient NKT cells participate in severe hepatitis through dysregulated cross-talk inhibition of IFN-gamma and IL-4 signaling in vivo. Immunity 14:535.
-
(2001)
Immunity
, vol.14
, pp. 535
-
-
Naka, T.1
Tsutsui, H.2
Fujimoto, M.3
Kawazoe, Y.4
Kohzaki, H.5
Morita, Y.6
Nakagawa, R.7
Narazaki, M.8
Adachi, K.9
Yoshimoto, T.10
Nakanishi, K.11
Kishimoto, T.12
-
16
-
-
0037438475
-
Suppressor of cytokine signaling-1 has IFN-gamma-independent actions in T cell homeostasis
-
Cornish, A. L., Davey, G. M., Metcalf, D., Purton, J. F., Corbin, J. E., Greenhalgh, C. J., Darwiche, R., Wu, L., Nicola, N. A., Godfrey, D. I., Heath, W. R., Hilton, D. J., Alexander, W. S. and Starr, R. 2003. Suppressor of cytokine signaling-1 has IFN-gamma-independent actions in T cell homeostasis. J. Immunol. 170:878.
-
(2003)
J. Immunol.
, vol.170
, pp. 878
-
-
Cornish, A.L.1
Davey, G.M.2
Metcalf, D.3
Purton, J.F.4
Corbin, J.E.5
Greenhalgh, C.J.6
Darwiche, R.7
Wu, L.8
Nicola, N.A.9
Godfrey, D.I.10
Heath, W.R.11
Hilton, D.J.12
Alexander, W.S.13
Starr, R.14
-
17
-
-
0028795226
-
Defective IL-5-receptor-mediated signaling in B cells of X-linked immunodeficient mice
-
Koike, M., Kikuchi, Y., Tominaga, A., Takaki, S., Akagi, K., Miyazaki, J., Yamamura, K. and Takatsu, K. 1995. Defective IL-5-receptor-mediated signaling in B cells of X-linked immunodeficient mice. Int. Immunol. 7:21.
-
(1995)
Int. Immunol.
, vol.7
, pp. 21
-
-
Koike, M.1
Kikuchi, Y.2
Tominaga, A.3
Takaki, S.4
Akagi, K.5
Miyazaki, J.6
Yamamura, K.7
Takatsu, K.8
-
18
-
-
0034663932
-
Defective thymocyte development and perturbed homeostasis of T cells in STAT-induced STAT inhibitor-1/suppressors of cytokine signaling-1 transgenic mice
-
Fujimoto, M., Naka, T., Nakagawa, R., Kawazoe, Y., Morita, Y., Tateishi, A., Okumura, K., Narazaki, M. and Kishimoto, T. 2000. Defective thymocyte development and perturbed homeostasis of T cells in STAT-induced STAT inhibitor-1/suppressors of cytokine signaling-1 transgenic mice. J. Immunol. 165:1799.
-
(2000)
J. Immunol.
, vol.165
, pp. 1799
-
-
Fujimoto, M.1
Naka, T.2
Nakagawa, R.3
Kawazoe, Y.4
Morita, Y.5
Tateishi, A.6
Okumura, K.7
Narazaki, M.8
Kishimoto, T.9
-
19
-
-
0035862334
-
Signal transducer and activator of transcription (STAT)-induced STAT inhibitor 1 (SSI-1)/suppressor of cytokine signaling 1 (SOCS1) inhibits insulin signal transduction pathway through modulating insulin receptor substrate 1 (IRS-1) phosphorylation
-
Kawazoe, Y., Naka, T., Fujimoto, M., Kohzaki, H., Morita, Y., Narazaki, M., Okumura, K., Saitoh, H., Nakagawa, R., Uchiyama, Y., Akira, S. and Kishimoto, T. 2001. Signal transducer and activator of transcription (STAT)-induced STAT inhibitor 1 (SSI-1)/suppressor of cytokine signaling 1 (SOCS1) inhibits insulin signal transduction pathway through modulating insulin receptor substrate 1 (IRS-1) phosphorylation. J. Exp. Med. 193:263.
-
(2001)
J. Exp. Med.
, vol.193
, pp. 263
-
-
Kawazoe, Y.1
Naka, T.2
Fujimoto, M.3
Kohzaki, H.4
Morita, Y.5
Narazaki, M.6
Okumura, K.7
Saitoh, H.8
Nakagawa, R.9
Uchiyama, Y.10
Akira, S.11
Kishimoto, T.12
-
20
-
-
0036707521
-
200Z PI3K-mediated negative feedback regulation of IL-12 production in DC
-
Fukao, T., Tanabe, M., Terauchi, Y., Ota, T., Matsuda, S., Asano, T., Kadowaki, T., Takeuchi, T. and Koyasu, S. 200Z PI3K-mediated negative feedback regulation of IL-12 production in DC. Nat. Immunol. 3:875.
-
Nat. Immunol.
, vol.3
, pp. 875
-
-
Fukao, T.1
Tanabe, M.2
Terauchi, Y.3
Ota, T.4
Matsuda, S.5
Asano, T.6
Kadowaki, T.7
Takeuchi, T.8
Koyasu, S.9
-
21
-
-
9344234460
-
IL-4 and anti-CD40 protect against Fas-mediated B cell apoptosis and induce B cell growth and differentiation
-
Nakanishi, K., Matsui, K., Kashiwamura, S., Nishioka, Y., Nomura, J., Nishimura, Y., Sakaguchi, N., Yonehara, S., Higashino, K. and Shinka, S. 1996. IL-4 and anti-CD40 protect against Fas-mediated B cell apoptosis and induce B cell growth and differentiation. Int. Immunol. 8:791.
-
(1996)
Int. Immunol.
, vol.8
, pp. 791
-
-
Nakanishi, K.1
Matsui, K.2
Kashiwamura, S.3
Nishioka, Y.4
Nomura, J.5
Nishimura, Y.6
Sakaguchi, N.7
Yonehara, S.8
Higashino, K.9
Shinka, S.10
-
22
-
-
0036849109
-
h polarization in vivo
-
h polarization in vivo. Int. Immunol. 14:1343.
-
(2002)
Int. Immunol.
, vol.14
, pp. 1343
-
-
Fujimoto, M.1
Tsutsui, H.2
Yumikura-Futatsugi, S.3
Ueda, H.4
Xingshou, O.5
Abe, T.6
Kawase, I.7
Nakanishi, K.8
Kishimoto, T.9
Naka, T.10
-
23
-
-
18744371050
-
SOCS-1 participates in negative regulation of LPS responses
-
Nakagawa, R., Naka, T., Tsutsui, H., Fujimoto, M., Kimura, A., Abe, T., Seki, E., Sato, S., Takeuchi, O., Takeda, K., Akira, S., Yamanishi, K., Kawase, I., Nakanishi, K. and Kishimoto, T. 2002. SOCS-1 participates in negative regulation of LPS responses. Immunity 17:677.
-
(2002)
Immunity
, vol.17
, pp. 677
-
-
Nakagawa, R.1
Naka, T.2
Tsutsui, H.3
Fujimoto, M.4
Kimura, A.5
Abe, T.6
Seki, E.7
Sato, S.8
Takeuchi, O.9
Takeda, K.10
Akira, S.11
Yamanishi, K.12
Kawase, I.13
Nakanishi, K.14
Kishimoto, T.15
-
24
-
-
0035395873
-
SOCS1 deficiency results in accelerated mammary gland development and rescues lactation in prolactin receptor-deficient mice
-
Lindeman, G. J., Wittlin, S., Lada, H., Naylor, M. J., Santamaria, M., Zhang, J. G., Starr, R., Hilton, D. J., Alexander, W. S., Ormandy, C. J. and Visvader, J. 2001. SOCS1 deficiency results in accelerated mammary gland development and rescues lactation in prolactin receptor-deficient mice. Genes Dev. 15:1631.
-
(2001)
Genes Dev.
, vol.15
, pp. 1631
-
-
Lindeman, G.J.1
Wittlin, S.2
Lada, H.3
Naylor, M.J.4
Santamaria, M.5
Zhang, J.G.6
Starr, R.7
Hilton, D.J.8
Alexander, W.S.9
Ormandy, C.J.10
Visvader, J.11
-
25
-
-
0034716925
-
Regulatory T cells: Key controllers of immunologic self-tolerance
-
Sakaguchi, S. 2000. Regulatory T cells: key controllers of immunologic self-tolerance. Cell 101:455.
-
(2000)
Cell
, vol.101
, pp. 455
-
-
Sakaguchi, S.1
-
26
-
-
0036597371
-
+ suppressor T cells: More questions than answers
-
+ suppressor T cells: more questions than answers. Nat. Rev. Immunol. 2:389.
-
(2002)
Nat. Rev. Immunol.
, vol.2
, pp. 389
-
-
Shevach, E.M.1
-
27
-
-
0035554676
-
Regulatory T cells in the control of immune pathology
-
Maloy, K. J. and Powrie, F. 2001. Regulatory T cells in the control of immune pathology. Nat. Immunol. 2:816.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 816
-
-
Maloy, K.J.1
Powrie, F.2
-
30
-
-
18344369175
-
The impact of T helper and T regulatory cells on the regulation of anti-double-stranded DNA B cells
-
Seo, S. J., Fields, M. L., Buckler, J. L., Reed, A. J., Mandik-Nayak, L., Nish, S. A., Noelle, R. J., Turka, L. A., Finkelman, F. D., Caton, A. J. and Erikson, J. 2002. The impact of T helper and T regulatory cells on the regulation of anti-double-stranded DNA B cells. Immunity 16:535.
-
(2002)
Immunity
, vol.16
, pp. 535
-
-
Seo, S.J.1
Fields, M.L.2
Buckler, J.L.3
Reed, A.J.4
Mandik-Nayak, L.5
Nish, S.A.6
Noelle, R.J.7
Turka, L.A.8
Finkelman, F.D.9
Caton, A.J.10
Erikson, J.11
-
31
-
-
0035198252
-
B cells and professional APCs recruit regulatory T cells via CCL4
-
Bystry, R. S., Aluvihare, V., Welch, K. A., Kallikourdis, M. and Betz, A. G. 2001. B cells and professional APCs recruit regulatory T cells via CCL4. Nat. Immunol, 2:1126.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 1126
-
-
Bystry, R.S.1
Aluvihare, V.2
Welch, K.A.3
Kallikourdis, M.4
Betz, A.G.5
-
32
-
-
0031647622
-
+ naturally anergic and suppressive T cells: Induction of autoimmune disease by breaking their anergic/suppressive state
-
+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state. Int. Immunol. 10:1969.
-
(1998)
Int. Immunol.
, vol.10
, pp. 1969
-
-
Takahashi, T.1
Kuniyasu, Y.2
Toda, M.3
Sakaguchi, N.4
Itoh, M.5
Iwata, M.6
Shimizu, J.7
Sakaguchi, S.8
-
33
-
-
0031821875
-
+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
-
+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. J. Exp. Med. 188:287.
-
(1998)
J. Exp. Med.
, vol.188
, pp. 287
-
-
Thornton, A.M.1
Shevach, E.M.2
-
34
-
-
0035168683
-
JAB/SOCS1/SSI-1 is an interleukin-2-induced inhibitor of IL-2 signaling
-
Sporri, B., Kovanen, P. E., Sasaki, A., Yoshimura, A. and Leonard, W. J. 2001. JAB/SOCS1/SSI-1 is an interleukin-2-induced inhibitor of IL-2 signaling. Blood 97:221.
-
(2001)
Blood
, vol.97
, pp. 221
-
-
Sporri, B.1
Kovanen, P.E.2
Sasaki, A.3
Yoshimura, A.4
Leonard, W.J.5
-
35
-
-
0037241115
-
Prolactin modulates the naive B cell repertoire
-
Peeva, E., Michael, D., Cleary, J., Rice, J., Chen, X. and Diamond, B. 2003. Prolactin modulates the naive B cell repertoire. J. Clin. Invest. 111:275.
-
(2003)
J. Clin. Invest.
, vol.111
, pp. 275
-
-
Peeva, E.1
Michael, D.2
Cleary, J.3
Rice, J.4
Chen, X.5
Diamond, B.6
-
36
-
-
0038807434
-
Negative regulation of interleukin-12 signaling by suppressor of cytokine signaling
-
Eyles, J. L., Metcalf, D., Grusby, M. J., Hilton, D. J. and Starr, R. 2002. Negative regulation of interleukin-12 signaling by suppressor of cytokine signaling. J. Biol. Chem. 277:43735.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 43735
-
-
Eyles, J.L.1
Metcalf, D.2
Grusby, M.J.3
Hilton, D.J.4
Starr, R.5
-
37
-
-
0037927824
-
Suppressor of cytokine signaling-1 regulates signaling in response to interleukin-2 and other gamma c-dependent cytokines in peripheral T cells
-
Cornish, A. L., Chong, M. M., Davey, G. M., Darwiche, R., Nicola, N. A., Hilton, D. J., Kay, T. W., Starr, R. and Alexander, W. S. 2003. Suppressor of cytokine signaling-1 regulates signaling in response to interleukin-2 and other gamma c-dependent cytokines in peripheral T cells. J. Biol. Chem. 278:22755.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 22755
-
-
Cornish, A.L.1
Chong, M.M.2
Davey, G.M.3
Darwiche, R.4
Nicola, N.A.5
Hilton, D.J.6
Kay, T.W.7
Starr, R.8
Alexander, W.S.9
-
38
-
-
0034679560
-
+ regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4
-
+ regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4. J. Exp. Med. 192:303.
-
(2000)
J. Exp. Med.
, vol.192
, pp. 303
-
-
Takahashi, T.1
Tagami, T.2
Yamazaki, S.3
Uede, T.4
Shimizu, J.5
Sakaguchi, N.6
Mak, T.W.7
Sakaguchi, S.8
-
41
-
-
0030708809
-
Host modifier genes affect mouse autoimmunity induced by the Ipr gene
-
Wang, Y., Nose, M., Kamoto, T., Nishimura, M. and Hiai, H. 1997. Host modifier genes affect mouse autoimmunity induced by the Ipr gene. Am. J. Pathol. 151:1791.
-
(1997)
Am. J. Pathol.
, vol.151
, pp. 1791
-
-
Wang, Y.1
Nose, M.2
Kamoto, T.3
Nishimura, M.4
Hiai, H.5
-
42
-
-
0035068349
-
Inactivation of SSI-1, a JAK/STAT inhibitor, in human hepatocellular carcinomas, as revealed by two-dimensional electrophoresis
-
Nagai, H., Kim, Y. S., Lee, K. T., Chu, M. Y., Konishi, N., Fujimoto, J., Baba, M., Matsubara, K. and Emi, M. 2001. Inactivation of SSI-1, a JAK/STAT inhibitor, in human hepatocellular carcinomas, as revealed by two-dimensional electrophoresis. J. Hepatol. 34:416.
-
(2001)
J. Hepatol.
, vol.34
, pp. 416
-
-
Nagai, H.1
Kim, Y.S.2
Lee, K.T.3
Chu, M.Y.4
Konishi, N.5
Fujimoto, J.6
Baba, M.7
Matsubara, K.8
Emi, M.9
-
43
-
-
0035042611
-
SOCS-1, a negative regulator of the JAK/STAT pathway, is silenced by methylation in human hepatocellular carcinoma and shows growth-suppression activity
-
Yoshikawa, H., Matsubara, K., Qian, G. S., Jackson, P., Groopman, J. D., Manning, J. E., Harris, C. C. and Herman, J. G. 2001. SOCS-1, a negative regulator of the JAK/STAT pathway, is silenced by methylation in human hepatocellular carcinoma and shows growth-suppression activity. Nat. Genet. 28:29.
-
(2001)
Nat. Genet.
, vol.28
, pp. 29
-
-
Yoshikawa, H.1
Matsubara, K.2
Qian, G.S.3
Jackson, P.4
Groopman, J.D.5
Manning, J.E.6
Harris, C.C.7
Herman, J.G.8
|