-
1
-
-
33747200808
-
Combining docking and molecular dynamic simulations in drug design
-
Alonso H, Bliznyuk AA, Gready JE. 2006. Combining docking and molecular dynamic simulations in drug design. Med. Res. Rev. 26:531-568.
-
(2006)
Med. Res. Rev
, vol.26
, pp. 531-568
-
-
Alonso, H.1
Bliznyuk, A.A.2
Gready, J.E.3
-
2
-
-
0037267333
-
Validating Survivin as a cancer therapeutic target
-
Altieri DC. 2003. Validating Survivin as a cancer therapeutic target. Nat. Rev. Cancer 3: 46-54.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 46-54
-
-
Altieri, D.C.1
-
3
-
-
0033654297
-
Generalized Born models of macromolecular solvation effects
-
Bashford D, Case TA. 2000. Generalized Born models of macromolecular solvation effects. Annu. Rev. Phys. Chem. 51: 129-152.
-
(2000)
Annu. Rev. Phys. Chem
, vol.51
, pp. 129-152
-
-
Bashford, D.1
Case, T.A.2
-
4
-
-
0026612756
-
Electrostatic calculations of the pKa values of ionizable groups in bacteriorhodopsin
-
Bashford D, Gerwert K. 1992. Electrostatic calculations of the pKa values of ionizable groups in bacteriorhodopsin. J. Mol. Biol. 224: 473-486.
-
(1992)
J. Mol. Biol
, vol.224
, pp. 473-486
-
-
Bashford, D.1
Gerwert, K.2
-
5
-
-
33750587438
-
Molecular dynamics with coupling to an external bath
-
Berendsen HJC, Postman JPM, Van Gunsteren WF, DiNola A, Haak JR. 1984. Molecular dynamics with coupling to an external bath. J. Chem. Phys. 81: 3684-3690.
-
(1984)
J. Chem. Phys
, vol.81
, pp. 3684-3690
-
-
Berendsen, H.J.C.1
Postman, J.P.M.2
Van Gunsteren, W.F.3
DiNola, A.4
Haak, J.R.5
-
6
-
-
44949245966
-
-
Case DA, Pearlman DA, Caldwell JW, Cheathan TE III, Wang J, Ross WS, Simmerling CL, Darden TD, Merz KM, Stanton RV, Cheng AL, Vincent JJ, Crowley M, Tsui V, Gohlke H, Radmer RJ, Duan Y, Pitera J, Massova I, Seibel GL, Sligh UC, Weiner PK, Kollman PA. 2002. AMBER 7, University of California, San Francisco.
-
Case DA, Pearlman DA, Caldwell JW, Cheathan TE III, Wang J, Ross WS, Simmerling CL, Darden TD, Merz KM, Stanton RV, Cheng AL, Vincent JJ, Crowley M, Tsui V, Gohlke H, Radmer RJ, Duan Y, Pitera J, Massova I, Seibel GL, Sligh UC, Weiner PK, Kollman PA. 2002. AMBER 7, University of California, San Francisco.
-
-
-
-
7
-
-
0035831021
-
Structural basis of Caspase-7 inhibition by XIAP
-
Chai J, Schiozaki E, Srinivasula S, Wu Q, Dataa P, Alnemri E, Shi T. 2001. Structural basis of Caspase-7 inhibition by XIAP. Cell 104: 769-780.
-
(2001)
Cell
, vol.104
, pp. 769-780
-
-
Chai, J.1
Schiozaki, E.2
Srinivasula, S.3
Wu, Q.4
Dataa, P.5
Alnemri, E.6
Shi, T.7
-
8
-
-
0033635270
-
Crystal structure of human survivin reveals a bow tie-shaped dimer with two unusual alpha-helical extensions
-
Chantalat L, Skoufias DA, Kleman JP, Jung B, Dideberg O, Margolis RL. 2000. Crystal structure of human survivin reveals a bow tie-shaped dimer with two unusual alpha-helical extensions. Mol. Cell 6: 183-189.
-
(2000)
Mol. Cell
, vol.6
, pp. 183-189
-
-
Chantalat, L.1
Skoufias, D.A.2
Kleman, J.P.3
Jung, B.4
Dideberg, O.5
Margolis, R.L.6
-
9
-
-
33749259614
-
Design, synthesis, and characterization of new embelin derivatives as potent inhibitors of X-linked inhibitor of apoptosis protein
-
Chen J, Nikolovska-Coleska Z, Wang G, Qiu S, Wang S. 2006. Design, synthesis, and characterization of new embelin derivatives as potent inhibitors of X-linked inhibitor of apoptosis protein. Bioorg. Med. Chem. Lett. 18: 5805-5808.
-
(2006)
Bioorg. Med. Chem. Lett
, vol.18
, pp. 5805-5808
-
-
Chen, J.1
Nikolovska-Coleska, Z.2
Wang, G.3
Qiu, S.4
Wang, S.5
-
10
-
-
0029011701
-
A second generation force field for the simulation of proteins, nucleic acids, and organic molecules
-
Cornell WD, Cieplak P, Bayly CL, Goud IR, Mertz KM Jr., Ferguson DM, Spellmeyer DC, Fox T, Caldwell JW, Kollman PA. 1995. A second generation force field for the simulation of proteins, nucleic acids, and organic molecules. J. Am. Chem. Soc. 117: 5179-5197.
-
(1995)
J. Am. Chem. Soc
, vol.117
, pp. 5179-5197
-
-
Cornell, W.D.1
Cieplak, P.2
Bayly, C.L.3
Goud, I.R.4
Mertz Jr., K.M.5
Ferguson, D.M.6
Spellmeyer, D.C.7
Fox, T.8
Caldwell, J.W.9
Kollman, P.A.10
-
11
-
-
33846823909
-
Particle mesh Ewald: An N log (N) method for Ewald sums in large systems
-
Darden T, York D, Pedersen L 1993. Particle mesh Ewald: an N log (N) method for Ewald sums in large systems. J. Chem. Phys. 98: 10089-10092.
-
(1993)
J. Chem. Phys
, vol.98
, pp. 10089-10092
-
-
Darden, T.1
York, D.2
Pedersen, L.3
-
12
-
-
12144289984
-
Glide: A new approach for rapid, accurate docking and scoring. 1. Methods and assessment of docking accuracy
-
Friesner RA, Banks JL, Murphy RB, Halgren TA, Klicic JJ, Mainz DT, Repasky MR Knoll EH, Shelley M, Perry JK, Shaw DE, Francis P, Shenkin PS. 2004. Glide: a new approach for rapid, accurate docking and scoring. 1. Methods and assessment of docking accuracy. J. Med. Chem. 47: 1739-1749.
-
(2004)
J. Med. Chem
, vol.47
, pp. 1739-1749
-
-
Friesner, R.A.1
Banks, J.L.2
Murphy, R.B.3
Halgren, T.A.4
Klicic, J.J.5
Mainz, D.T.6
Repasky, M.R.7
Knoll, E.H.8
Shelley, M.9
Perry, J.K.10
Shaw, D.E.11
Francis, P.12
Shenkin, P.S.13
-
13
-
-
44949157413
-
-
Frisch MJ, Trucks GW, Schlegel HB, Scuseria GE, Robb MA, Cheeseman JR, Zakrzewski VG, Montgomery JA Jr., Stratmann RE, Burant JC, Dapprich S, Millam JM, Daniels AD, Kudin KN, Strain MC, Farkas O, Tomasi J, Barone V, Cossi M, Cammi R, Mennucci B, Pomelli C, Adamo C, Clifford S, Ochterski J, Petersson GA, Ayala PY, Cui Q, Morokuma K, Malick DK, Rabuck AD, Raghavachari K, Foresman JB, Cioslowski J, Ortiz JV, Baboul AG, Stefanov BB, Liu G, Liashenko A, Piskorz R Komaromi I, Gomperts R, Martin RL, Fox DJ, Keith T, Al-Laham MA, Peng CY, Nanayakkara A, Gonzalez C, Challacombe M, Gill PMW, Johnson B, Chen W, Wong MW, Andres JL, Head-Gordon M, Replogle ES, Pople JA. 1998. Gaussian 98. Revision A.6. Gaussian, Inc., Pittsburgh, PA.
-
Frisch MJ, Trucks GW, Schlegel HB, Scuseria GE, Robb MA, Cheeseman JR, Zakrzewski VG, Montgomery JA Jr., Stratmann RE, Burant JC, Dapprich S, Millam JM, Daniels AD, Kudin KN, Strain MC, Farkas O, Tomasi J, Barone V, Cossi M, Cammi R, Mennucci B, Pomelli C, Adamo C, Clifford S, Ochterski J, Petersson GA, Ayala PY, Cui Q, Morokuma K, Malick DK, Rabuck AD, Raghavachari K, Foresman JB, Cioslowski J, Ortiz JV, Baboul AG, Stefanov BB, Liu G, Liashenko A, Piskorz R Komaromi I, Gomperts R, Martin RL, Fox DJ, Keith T, Al-Laham MA, Peng CY, Nanayakkara A, Gonzalez C, Challacombe M, Gill PMW, Johnson B, Chen W, Wong MW, Andres JL, Head-Gordon M, Replogle ES, Pople JA. 1998. Gaussian 98. Revision A.6. Gaussian, Inc., Pittsburgh, PA.
-
-
-
-
14
-
-
12444295103
-
A high-throughput screen for identification of molecular mimics of Smac/DIABLO utilizing a fluorescence polarization assay
-
Glover CJ, Hite K, DeLosh R, Scudiero DA, Fivash MJ, Smith LR, Fisher RJ, Wu J, Shi Y, Kipp RA, McLendon GL, Sausville EA, Shoemaker RH. 2003. A high-throughput screen for identification of molecular mimics of Smac/DIABLO utilizing a fluorescence polarization assay. Anal. Biochem. 320: 157-169.
-
(2003)
Anal. Biochem
, vol.320
, pp. 157-169
-
-
Glover, C.J.1
Hite, K.2
DeLosh, R.3
Scudiero, D.A.4
Fivash, M.J.5
Smith, L.R.6
Fisher, R.J.7
Wu, J.8
Shi, Y.9
Kipp, R.A.10
McLendon, G.L.11
Sausville, E.A.12
Shoemaker, R.H.13
-
16
-
-
0036547417
-
Death and anti-death: Tumour resistance to apoptosis
-
Igney FH, Krammer PH. 2002. Death and anti-death: tumour resistance to apoptosis. Nat. Rev. Cancer. 2: 277-288.
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 277-288
-
-
Igney, F.H.1
Krammer, P.H.2
-
17
-
-
0004016501
-
Comparison of simple potential functions for simulating liquid water
-
Jorgensen WL, Chandresekhar J, Madura J, Impey R, Klein M. 1983. Comparison of simple potential functions for simulating liquid water. J. Chem. Phys. 79: 926-935.
-
(1983)
J. Chem. Phys
, vol.79
, pp. 926-935
-
-
Jorgensen, W.L.1
Chandresekhar, J.2
Madura, J.3
Impey, R.4
Klein, M.5
-
18
-
-
0035913529
-
Evaluation and reparametrization of the OPLS-AA force field from proteins via comparison with accurate quantum chemical calculations on peptides
-
Kaminski GA, Friesner RA, Tirado-Rives J, Jorgensen WL. 2001. Evaluation and reparametrization of the OPLS-AA force field from proteins via comparison with accurate quantum chemical calculations on peptides. J. Phys. Chem. B. 105: 6474-6487.
-
(2001)
J. Phys. Chem. B
, vol.105
, pp. 6474-6487
-
-
Kaminski, G.A.1
Friesner, R.A.2
Tirado-Rives, J.3
Jorgensen, W.L.4
-
19
-
-
0037062585
-
Molecular targeting of inhibitor of apoptosis proteins based on small molecule mimics of natural binding partners
-
Kipp RA, Case MA, Wist AD, Cresson CM, Carrell M, Griner E, Wiita A, Albiniak PA, Chai J, Shi Y, Semmelhack F, McLendon GL. 2002. Molecular targeting of inhibitor of apoptosis proteins based on small molecule mimics of natural binding partners. Biochemistry 41: 7344-7349.
-
(2002)
Biochemistry
, vol.41
, pp. 7344-7349
-
-
Kipp, R.A.1
Case, M.A.2
Wist, A.D.3
Cresson, C.M.4
Carrell, M.5
Griner, E.6
Wiita, A.7
Albiniak, P.A.8
Chai, J.9
Shi, Y.10
Semmelhack, F.11
McLendon, G.L.12
-
20
-
-
4444243683
-
A small molecule Smac mimic potentiates TRAIL- and TNFα-mediated cell death
-
Li L, Thomas RM, Suzuki H, De Brabander JK, Wang X, Harran PG. 2004. A small molecule Smac mimic potentiates TRAIL- and TNFα-mediated cell death. Science 305: 1471-1474.
-
(2004)
Science
, vol.305
, pp. 1471-1474
-
-
Li, L.1
Thomas, R.M.2
Suzuki, H.3
De Brabander, J.K.4
Wang, X.5
Harran, P.G.6
-
21
-
-
0034700495
-
Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain
-
Liu Z, Sun C, Olejniczak E, Meadows R, Betz S, Oost T, Herrmann J, Wu J, Fesik S. 2000. Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain. Nature 408: 1004-1008.
-
(2000)
Nature
, vol.408
, pp. 1004-1008
-
-
Liu, Z.1
Sun, C.2
Olejniczak, E.3
Meadows, R.4
Betz, S.5
Oost, T.6
Herrmann, J.7
Wu, J.8
Fesik, S.9
-
22
-
-
0037016707
-
The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif
-
Martins LM, Iaccarino I, Tenev T, Gschmeissner S, Totty NF, Lemoine NR, Savopoulos J, Gray CW, Creasy CL, Dingwall C, Downward J. 2002. The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif. J. Biol. Chem. 277: 439-444.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 439-444
-
-
Martins, L.M.1
Iaccarino, I.2
Tenev, T.3
Gschmeissner, S.4
Totty, N.F.5
Lemoine, N.R.6
Savopoulos, J.7
Gray, C.W.8
Creasy, C.L.9
Dingwall, C.10
Downward, J.11
-
23
-
-
0038297558
-
Expression of Smac/DIABLO in ovarian carcinoma cells induces apoptosis via a Caspase-9-mediated pathway
-
McNeish IA, Bell S, Mckay T, Tenev T, Marani M, Lemoine NR. 2003. Expression of Smac/DIABLO in ovarian carcinoma cells induces apoptosis via a Caspase-9-mediated pathway. Exp. Cell Res. 286: 186-198.
-
(2003)
Exp. Cell Res
, vol.286
, pp. 186-198
-
-
McNeish, I.A.1
Bell, S.2
Mckay, T.3
Tenev, T.4
Marani, M.5
Lemoine, N.R.6
-
24
-
-
0037500905
-
X-linked Inhibitor of apoptosis (XIAP) blocks Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis of prostate cancer cells in the presence of mitochondrial activation: Sensitization by overexpression of second mitochondria-derived activator of Caspase/direct IAP-binding protein with low pi (Smac/DIABLO)
-
Ng CP, Bonavida B. 2002. X-linked Inhibitor of apoptosis (XIAP) blocks Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis of prostate cancer cells in the presence of mitochondrial activation: sensitization by overexpression of second mitochondria-derived activator of Caspase/direct IAP-binding protein with low pi (Smac/DIABLO). Mol. Cancer Ther. 1: 1051-1058.
-
(2002)
Mol. Cancer Ther
, vol.1
, pp. 1051-1058
-
-
Ng, C.P.1
Bonavida, B.2
-
25
-
-
2342448582
-
Discovery of embelin as a cell-permeable, small-molecular weight inhibitor of XIAP through structure-based computational screening of a traditional herbal medicine three-dimensional structure database
-
Nikolovska-Coleska Z, Xu L, Hu Z, Tomita Y, Li P, Roller P, Wang R, Fang X, Guo R, Zhang M, Lippman M, Yang D, Wang S. 2004. Discovery of embelin as a cell-permeable, small-molecular weight inhibitor of XIAP through structure-based computational screening of a traditional herbal medicine three-dimensional structure database. J. Med. Chem. 47: 2430-2440.
-
(2004)
J. Med. Chem
, vol.47
, pp. 2430-2440
-
-
Nikolovska-Coleska, Z.1
Xu, L.2
Hu, Z.3
Tomita, Y.4
Li, P.5
Roller, P.6
Wang, R.7
Fang, X.8
Guo, R.9
Zhang, M.10
Lippman, M.11
Yang, D.12
Wang, S.13
-
26
-
-
33846881144
-
Comparative evaluation of MMPBSA and XSCORE to compute binding free energy in XIAP-peptide complexes
-
Obiol-Pardo C, Rubio-Martinez J. 2007. Comparative evaluation of MMPBSA and XSCORE to compute binding free energy in XIAP-peptide complexes. J. Chem. Inform. Model. 47: 134-142.
-
(2007)
J. Chem. Inform. Model
, vol.47
, pp. 134-142
-
-
Obiol-Pardo, C.1
Rubio-Martinez, J.2
-
27
-
-
0038451324
-
Insight into the mechanism of the IMP-I metallo-b-lactamase by molecular dynamics simulations
-
Oelschlaeger P, Schmid DR, Pleiss J. 2003. Insight into the mechanism of the IMP-I metallo-b-lactamase by molecular dynamics simulations. Protein Eng. 16: 341-350.
-
(2003)
Protein Eng
, vol.16
, pp. 341-350
-
-
Oelschlaeger, P.1
Schmid, D.R.2
Pleiss, J.3
-
28
-
-
4143099131
-
Discovery of potent antagonists of the antiapoptotic protein XIAP for the treatment of cancer
-
Oost TK, Sun C, Armstrong RC, Al-Assaad A, Betz SF, Deckwerth TL, Ding H, Elmore SW, Meadows RP, Olejniczak ET, Oleksijew A, Oltersdorf T, Rosenberg SH, Shoemaker AR, Tomaselli KJ, Zou H, Fesik SW. 2004. Discovery of potent antagonists of the antiapoptotic protein XIAP for the treatment of cancer. J. Med. Chem. 47: 4417-4426.
-
(2004)
J. Med. Chem
, vol.47
, pp. 4417-4426
-
-
Oost, T.K.1
Sun, C.2
Armstrong, R.C.3
Al-Assaad, A.4
Betz, S.F.5
Deckwerth, T.L.6
Ding, H.7
Elmore, S.W.8
Meadows, R.P.9
Olejniczak, E.T.10
Oleksijew, A.11
Oltersdorf, T.12
Rosenberg, S.H.13
Shoemaker, A.R.14
Tomaselli, K.J.15
Zou, H.16
Fesik, S.W.17
-
29
-
-
0000510540
-
Novel zinc protein molecular dynamics simulations: Steps toward antiangiogenesis for cancer treatment
-
Pang YP. 1999. Novel zinc protein molecular dynamics simulations: steps toward antiangiogenesis for cancer treatment. J. Mol. Model. 5: 196-202.
-
(1999)
J. Mol. Model
, vol.5
, pp. 196-202
-
-
Pang, Y.P.1
-
30
-
-
0035889687
-
Successful molecular dynamics simulation of two zinc complexes bridged by a hydroxide in phosphotriesterase using the cationic dummy atom method
-
Pang YP. 2001. Successful molecular dynamics simulation of two zinc complexes bridged by a hydroxide in phosphotriesterase using the cationic dummy atom method. Proteins 45: 183-189.
-
(2001)
Proteins
, vol.45
, pp. 183-189
-
-
Pang, Y.P.1
-
31
-
-
0033769641
-
Successful molecular dynamics simulation of the zinc-bound farnesyltransferase using the cationic dummy atom approach
-
Pang Y, Xu K, El Yazla J, Prendergast F. 2000. Successful molecular dynamics simulation of the zinc-bound farnesyltransferase using the cationic dummy atom approach. Protein Scei. 9: 1857-1865.
-
(2000)
Protein Scei
, vol.9
, pp. 1857-1865
-
-
Pang, Y.1
Xu, K.2
El Yazla, J.3
Prendergast, F.4
-
32
-
-
12444292682
-
Non-peptidic small molecule inhibitors of XIAP
-
Park CM, Sun C, Olejniczak ET, Wilson AE, Meadows RP, Betz SF, Elmore SW, Fesik SW. 2005. Non-peptidic small molecule inhibitors of XIAP. Bioorg. Med. Chem. Lett. 15: 771-775.
-
(2005)
Bioorg. Med. Chem. Lett
, vol.15
, pp. 771-775
-
-
Park, C.M.1
Sun, C.2
Olejniczak, E.T.3
Wilson, A.E.4
Meadows, R.P.5
Betz, S.F.6
Elmore, S.W.7
Fesik, S.W.8
-
33
-
-
28144441347
-
Evaluating the molecular mechanics Poisson-Boltzmann surface area free energy method using a cogeneric series of ligands to p38 MAP kinase
-
Pearlman DA. 2005. Evaluating the molecular mechanics Poisson-Boltzmann surface area free energy method using a cogeneric series of ligands to p38 MAP kinase. J. Med. Chem. 48: 7796-7806.
-
(2005)
J. Med. Chem
, vol.48
, pp. 7796-7806
-
-
Pearlman, D.A.1
-
34
-
-
4444221565
-
UCSF Chimera - a visualization system for exploratory research and analysis
-
Pettersen EF, Goddard TD, Huang CC, Couch GS, Greenblatt DM, Meng EC, Ferrin TE. 2004. UCSF Chimera - a visualization system for exploratory research and analysis. J. Comput. Chem. 25: 1605-1612.
-
(2004)
J. Comput. Chem
, vol.25
, pp. 1605-1612
-
-
Pettersen, E.F.1
Goddard, T.D.2
Huang, C.C.3
Couch, G.S.4
Greenblatt, D.M.5
Meng, E.C.6
Ferrin, T.E.7
-
35
-
-
0036463649
-
Apoptosis-based therapies
-
Reed JC 2002. Apoptosis-based therapies. Nat. Rev. Drug Discov. 1: 111-121.
-
(2002)
Nat. Rev. Drug Discov
, vol.1
, pp. 111-121
-
-
Reed, J.C.1
-
36
-
-
0035831019
-
Structural basis for the inhibition of Caspase-3 by XIAP
-
Riedl S, Renatus M, Schwarzenbacher R, Zhou Q, Sun C, Fesik S, Liddington R, Salvessen G. 2001. Structural basis for the inhibition of Caspase-3 by XIAP. Cell 104: 791-800.
-
(2001)
Cell
, vol.104
, pp. 791-800
-
-
Riedl, S.1
Renatus, M.2
Schwarzenbacher, R.3
Zhou, Q.4
Sun, C.5
Fesik, S.6
Liddington, R.7
Salvessen, G.8
-
37
-
-
0037080244
-
Rapid grid-based construction of the molecular surface and the use of induced surface charge to calculate reaction field energies: Applications to the molecular systems and geometric objects
-
Rocchia W, Sridharan S, Nicholls A, Alexov E, Chiabrera A, Honig B. 2002. Rapid grid-based construction of the molecular surface and the use of induced surface charge to calculate reaction field energies: applications to the molecular systems and geometric objects. J. Comput. Chem. 23: 128-137.
-
(2002)
J. Comput. Chem
, vol.23
, pp. 128-137
-
-
Rocchia, W.1
Sridharan, S.2
Nicholls, A.3
Alexov, E.4
Chiabrera, A.5
Honig, B.6
-
39
-
-
33646940952
-
Numerical integration of the cartesian equations of motion of a system with constraints: Molecular dynamics of n-alkanes
-
Ryckaert JP, Ciccotti G, Berendsen HJ. 1977. Numerical integration of the cartesian equations of motion of a system with constraints: molecular dynamics of n-alkanes. J. Comput. Chem. 23: 327-341.
-
(1977)
J. Comput. Chem
, vol.23
, pp. 327-341
-
-
Ryckaert, J.P.1
Ciccotti, G.2
Berendsen, H.J.3
-
40
-
-
0036810764
-
Peptides in apoptosis research
-
Salgado J, Garcia-Saez A, Malet G, Mingarro I, Perez-Paya E. 2002. Peptides in apoptosis research. J. Pept. Sci. 8: 543-560.
-
(2002)
J. Pept. Sci
, vol.8
, pp. 543-560
-
-
Salgado, J.1
Garcia-Saez, A.2
Malet, G.3
Mingarro, I.4
Perez-Paya, E.5
-
41
-
-
0036088471
-
IAP proteins: Blocking the road to death's door
-
Salvesen GS, Duckett CS. 2002. IAP proteins: blocking the road to death's door. Mol. Cell Biol. 3: 401-410.
-
(2002)
Mol. Cell Biol
, vol.3
, pp. 401-410
-
-
Salvesen, G.S.1
Duckett, C.S.2
-
43
-
-
3042674026
-
Overexpression of X-linked inhibitor of apoptosis in human hepatocellular carcinoma
-
Shiraki K, Sugimoto K, Yamanaka Y, Yamaguchi Y, Saitou Y, Ito K, Yamamoto N, Yamanaka T, Fujikawa K, Murata K, Kano T. 2003. Overexpression of X-linked inhibitor of apoptosis in human hepatocellular carcinoma. Int. J. Mol. Med. 12: 705-708.
-
(2003)
Int. J. Mol. Med
, vol.12
, pp. 705-708
-
-
Shiraki, K.1
Sugimoto, K.2
Yamanaka, Y.3
Yamaguchi, Y.4
Saitou, Y.5
Ito, K.6
Yamamoto, N.7
Yamanaka, T.8
Fujikawa, K.9
Murata, K.10
Kano, T.11
-
44
-
-
0037663452
-
Direct interaction between survivin and Smac/DIABLO is essential for the anti-apoptotic activity of survivin during taxol-induced apoptosis
-
Song Z, Yao X, Wu M. 2003. Direct interaction between survivin and Smac/DIABLO is essential for the anti-apoptotic activity of survivin during taxol-induced apoptosis. J. Biol. Chem. 278: 23130-23140.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 23130-23140
-
-
Song, Z.1
Yao, X.2
Wu, M.3
-
45
-
-
0035282570
-
A conserved XIA-P-interaction motif in Caspase-9 and Smac/DIABLO regulates Caspase activity and apoptosis
-
Srinivasula S, Ramesh H, Saleh A, Datta P, Shiozaki E, Chai J, Lee R, Robbins PD, Fernandes-Alnemri T, Shi Y, Alnemri E. 2001. A conserved XIA-P-interaction motif in Caspase-9 and Smac/DIABLO regulates Caspase activity and apoptosis. Nature 410: 112-116.
-
(2001)
Nature
, vol.410
, pp. 112-116
-
-
Srinivasula, S.1
Ramesh, H.2
Saleh, A.3
Datta, P.4
Shiozaki, E.5
Chai, J.6
Lee, R.7
Robbins, P.D.8
Fernandes-Alnemri, T.9
Shi, Y.10
Alnemri, E.11
-
46
-
-
19944434282
-
Structure-based design, synthesis and biochemical testing of novel and potent Smac peptido-mimetics
-
Sun H, Nikolovska-Coleska Z, Chen J, Chao-Yie Yang CY, Tomita Y, Pan H, Yoshioka Y, Krajewski K, Rollere PP, Wang S. 2005a. Structure-based design, synthesis and biochemical testing of novel and potent Smac peptido-mimetics. Bioorg. Med. Chem. Lett. 15: 793-797.
-
(2005)
Bioorg. Med. Chem. Lett
, vol.15
, pp. 793-797
-
-
Sun, H.1
Nikolovska-Coleska, Z.2
Chen, J.3
Chao-Yie Yang, C.Y.4
Tomita, Y.5
Pan, H.6
Yoshioka, Y.7
Krajewski, K.8
Rollere, P.P.9
Wang, S.10
-
47
-
-
11844252553
-
Solution structure of human Survivin and its binding interface with Smac/Diablo
-
Sun C, Nettesheim D, Liu Z, Olejniczak ET. 2005b. Solution structure of human Survivin and its binding interface with Smac/Diablo. Biochemistry 44: 11-17.
-
(2005)
Biochemistry
, vol.44
, pp. 11-17
-
-
Sun, C.1
Nettesheim, D.2
Liu, Z.3
Olejniczak, E.T.4
-
48
-
-
0035920126
-
X-linked inhibitor of apoptosis protein (XIAP) inhibits Caspase-3 and -7 in distinct modes
-
Suzuki Y, Nakabayashi Y, Kazuko N, Reed J, Takahashi R. 2001. X-linked inhibitor of apoptosis protein (XIAP) inhibits Caspase-3 and -7 in distinct modes. J. Biol. Chem. 276: 27058-27063.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 27058-27063
-
-
Suzuki, Y.1
Nakabayashi, Y.2
Kazuko, N.3
Reed, J.4
Takahashi, R.5
-
49
-
-
17144438370
-
Expression and prognostic significance of IAP-family genes in human cancers and myeloid leukemias
-
Tamm I, Kornblau SM, Segall H, Krajewski S, Welsh K, Kitada S, Scudiero DA, Tudor G, Qui YH, Monks A, Andreeff M, Reed JC. 2000. Expression and prognostic significance of IAP-family genes in human cancers and myeloid leukemias. Clin. Cancer Res. 6: 1796-1803.
-
(2000)
Clin. Cancer Res
, vol.6
, pp. 1796-1803
-
-
Tamm, I.1
Kornblau, S.M.2
Segall, H.3
Krajewski, S.4
Welsh, K.5
Kitada, S.6
Scudiero, D.A.7
Tudor, G.8
Qui, Y.H.9
Monks, A.10
Andreeff, M.11
Reed, J.C.12
-
50
-
-
14244273182
-
Theory and applications of the generalized born solvation model in macromolecular simulations
-
Tsui V, Case DA. 2001. Theory and applications of the generalized born solvation model in macromolecular simulations. Nucleic Acid Sci. 56: 275-291.
-
(2001)
Nucleic Acid Sci
, vol.56
, pp. 275-291
-
-
Tsui, V.1
Case, D.A.2
-
51
-
-
0033923368
-
Structure of the human anti-apoptotic protein Survivin reveals a dimeric arrangement
-
Verdecia MA, Huang H, Dutil E, Kaiser DA, Hunter T, Noel JP. 2000. Structure of the human anti-apoptotic protein Survivin reveals a dimeric arrangement. Nat. Struct. Biol. 7: 602-608.
-
(2000)
Nat. Struct. Biol
, vol.7
, pp. 602-608
-
-
Verdecia, M.A.1
Huang, H.2
Dutil, E.3
Kaiser, D.A.4
Hunter, T.5
Noel, J.P.6
-
52
-
-
2942532422
-
Development and testing of a general amber force field
-
Wang J, Wolf RM, Caldwell JW, Kollman PA, Case DA. 2004. Development and testing of a general amber force field. J. Comput. Chem. 25: 1157-1174.
-
(2004)
J. Comput. Chem
, vol.25
, pp. 1157-1174
-
-
Wang, J.1
Wolf, R.M.2
Caldwell, J.W.3
Kollman, P.A.4
Case, D.A.5
-
53
-
-
0000408363
-
Approximate atomic surfaces from linear combinations of pairwise overlaps (LCPO)
-
Weiser J, Shemkin PS, Still WC. 1999. Approximate atomic surfaces from linear combinations of pairwise overlaps (LCPO). J. Comput. Chem. 20: 217-230.
-
(1999)
J. Comput. Chem
, vol.20
, pp. 217-230
-
-
Weiser, J.1
Shemkin, P.S.2
Still, W.C.3
-
54
-
-
0034700491
-
Structural basis of IAP recognition by Smac/DIABLO
-
Wu G, Chai J, Suber T, Wu J, Du C, Wang X, Shi Y. 2000. Structural basis of IAP recognition by Smac/DIABLO. Nature 408: 1008-1012.
-
(2000)
Nature
, vol.408
, pp. 1008-1012
-
-
Wu, G.1
Chai, J.2
Suber, T.3
Wu, J.4
Du, C.5
Wang, X.6
Shi, Y.7
-
55
-
-
0035476255
-
Tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis of human melanoma is regulated by Smac/DIABLO release from mitochondria
-
Zhang XD, Zhang XY, Gray CP, Nguyen T, Hersey P. 2001. Tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis of human melanoma is regulated by Smac/DIABLO release from mitochondria. Cancer Res. 61: 7339-7348.
-
(2001)
Cancer Res
, vol.61
, pp. 7339-7348
-
-
Zhang, X.D.1
Zhang, X.Y.2
Gray, C.P.3
Nguyen, T.4
Hersey, P.5
|