Design, synthesis, and characterization of new embelin derivatives as potent inhibitors of X-linked inhibitor of apoptosis protein

Bioorganic and Medicinal Chemistry Letters

Volumn 16, Issue 22, 2006, Pages 5805-5808

  Chen, Jianyong ^a   Nikolovska Coleska, Zaneta ^a   Wang, Guoping ^a   Qiu, Su ^a   Wang, Shaomeng ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Embelin; Small molecule inhibitors; XIAP

Indexed keywords

ANTINEOPLASTIC AGENT; EMBELIN; PROTEIN INHIBITOR; X LINKED INHIBITOR OF APOPTOSIS;

ARTICLE; BINDING ASSAY; DRUG BINDING; DRUG DESIGN; DRUG SYNTHESIS; HUMAN; HUMAN CELL;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BENZOQUINONES; BINDING, COMPETITIVE; BREAST NEOPLASMS; CELL LINE, TUMOR; COMPUTER SIMULATION; DATABASES, FACTUAL; DRUG DESIGN; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; HUMANS; STRUCTURE-ACTIVITY RELATIONSHIP; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

EID: 33749259614     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.08.072     Document Type: Article

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