Non-peptidic small molecule inhibitors of XIAP

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 3, 2005, Pages 771-775

  Park, Cheol Min ^a   Sun, Chaohong ^a   Olejniczak, Edward T ^a   Wilson, Alan E ^a   Meadows, Robert P ^a   Betz, Stephen F ^a   Elmore, Steven W ^a   Fesik, Stephen W ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

SMAC mimetics; XIAP inhibitors

Indexed keywords

IMIDAZOLE DERIVATIVE; PROTEIN INHIBITOR; THIAZOLE DERIVATIVE; UNCLASSIFIED DRUG; X LINKED INHIBITOR OF APOPTOSIS; X LINKED INHIBITOR OF APOPTOSIS INHIBITOR;

ARTICLE; DRUG DESIGN; DRUG PROTEIN BINDING; DRUG SYNTHESIS; PROTEIN DOMAIN; STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION;

BINDING SITES; DRUG DESIGN; HETEROCYCLIC COMPOUNDS; HUMANS; IMIDAZOLES; LIGANDS; MAGNETIC RESONANCE SPECTROSCOPY; PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLES; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

EID: 12444292682     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.11.010     Document Type: Article

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