메뉴 건너뛰기




Volumn 567, Issue 1, 2004, Pages 71-84

Know-how of RNA interference and its applications in research and therapy

Author keywords

Application; DNA methylation; miRNA; Research; RNA interference; siRNA

Indexed keywords

DOUBLE STRANDED RNA; ENDONUCLEASE; MESSENGER RNA; RNA INDUCED SILENCING COMPLEX; SMALL INTERFERING RNA;

EID: 4444346347     PISSN: 13835742     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrrev.2004.06.002     Document Type: Review
Times cited : (38)

References (86)
  • 1
    • 0001359591 scopus 로고
    • Introduction of a chimeric chalcone synthase gene into Petunia results in reversible co-suppression of homologous genes in trans
    • C. Napoli, C. Lemieux, and R. Jorgensen Introduction of a chimeric chalcone synthase gene into Petunia results in reversible co-suppression of homologous genes in trans Plant Cell. 2 1990 279 289
    • (1990) Plant Cell. , vol.2 , pp. 279-289
    • Napoli, C.1    Lemieux, C.2    Jorgensen, R.3
  • 3
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • A. Fire, S. Xu, M.K. Montgomery, S.A. Kostas, S.E. Driver, and C.C. Mello Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans Nature 391 1998 806 811
    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3    Kostas, S.A.4    Driver, S.E.5    Mello, C.C.6
  • 4
    • 0033573924 scopus 로고    scopus 로고
    • Targeted disruption of gene function in Drosophila by RNA interference (RNA-i): A role for nautilus in embryonic somatic muscle formation
    • L.B. Misquitta, and M. Paterson Targeted disruption of gene function in Drosophila by RNA interference (RNA-i): a role for nautilus in embryonic somatic muscle formation Proc. Natl. Acad. Sci. U.S.A. 96 1999 1451 1456
    • (1999) Proc. Natl. Acad. Sci. U.S.A. , vol.96 , pp. 1451-1456
    • Misquitta, L.B.1    Paterson, M.2
  • 5
    • 0029024475 scopus 로고
    • Par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed
    • S. Guo, and K.J. Kemphues par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed Cell 81 1995 611 620
    • (1995) Cell , vol.81 , pp. 611-620
    • Guo, S.1    Kemphues, K.J.2
  • 6
    • 0035942736 scopus 로고    scopus 로고
    • Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
    • S.M. Elbashir, J. Harborth, W. Lendeckel, A. Yalcin, K. Weber, and T. Tuschl Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells Nature 411 2001 494 498
    • (2001) Nature , vol.411 , pp. 494-498
    • Elbashir, S.M.1    Harborth, J.2    Lendeckel, W.3    Yalcin, A.4    Weber, K.5    Tuschl, T.6
  • 7
    • 0035966319 scopus 로고    scopus 로고
    • MicroRNAs: Tiny regulators with great potential
    • V. Ambros microRNAs: tiny regulators with great potential Cell 107 2001 823 826
    • (2001) Cell , vol.107 , pp. 823-826
    • Ambros, V.1
  • 8
    • 0038343499 scopus 로고    scopus 로고
    • MicroRNA pathways in flies and worms: Growth, death, fat, stress, and timing
    • V. Ambros MicroRNA pathways in flies and worms: growth, death, fat, stress, and timing Cell 113 2003 673 676
    • (2003) Cell , vol.113 , pp. 673-676
    • Ambros, V.1
  • 10
    • 0035797929 scopus 로고    scopus 로고
    • RNA interference: It's a small RNA world
    • E.G. Moss RNA interference: it's a small RNA world Curr. Biol. 11 2001 772 775
    • (2001) Curr. Biol. , vol.11 , pp. 772-775
    • Moss, E.G.1
  • 11
    • 0037133225 scopus 로고    scopus 로고
    • MicroRNAs: Hidden in the genome
    • E.G. Moss MicroRNAs: hidden in the genome Curr. Biol. 12 2002 R138 R140
    • (2002) Curr. Biol. , vol.12
    • Moss, E.G.1
  • 12
    • 0037146606 scopus 로고    scopus 로고
    • Breakthrough of the year. Small RNAs make big splash
    • J. Couzin Breakthrough of the year. Small RNAs make big splash Science 298 2002 2296 2297
    • (2002) Science , vol.298 , pp. 2296-2297
    • Couzin, J.1
  • 13
    • 0038299558 scopus 로고    scopus 로고
    • Role of microRNAs in plant and animal development
    • J.C. Carrington, and V. Ambros Role of microRNAs in plant and animal development Science 301 2003 336 338
    • (2003) Science , vol.301 , pp. 336-338
    • Carrington, J.C.1    Ambros, V.2
  • 14
    • 0037782493 scopus 로고    scopus 로고
    • MicroRNAs: At the root of plant development?
    • B. Bartel, and D.P. Bartel MicroRNAs: at the root of plant development? Plant Physiol. 132 2003 709 717
    • (2003) Plant Physiol. , vol.132 , pp. 709-717
    • Bartel, B.1    Bartel, D.P.2
  • 16
    • 0035905766 scopus 로고    scopus 로고
    • Role for a bidentate ribonuclease in the initiation step of RNA interference
    • E. Bernstein, A.A. Caudy, S.M. Hammond, and G.J. Hannon Role for a bidentate ribonuclease in the initiation step of RNA interference Nature 409 2001 363 366
    • (2001) Nature , vol.409 , pp. 363-366
    • Bernstein, E.1    Caudy, A.A.2    Hammond, S.M.3    Hannon, G.J.4
  • 19
    • 0037031576 scopus 로고    scopus 로고
    • Single-stranded antisense siRNAs guide target RNA cleavage in RNAi
    • J. Martinez, A. Patkaniowska, H. Urlaub, R. Luhrmann, and T. Tuschl Single-stranded antisense siRNAs guide target RNA cleavage in RNAi Cell 110 2002 563 574
    • (2002) Cell , vol.110 , pp. 563-574
    • Martinez, J.1    Patkaniowska, A.2    Urlaub, H.3    Luhrmann, R.4    Tuschl, T.5
  • 20
    • 0037238848 scopus 로고    scopus 로고
    • Gene silencing mediated by small interfering RNAs in mammalian cells
    • M. Scherr, M.A. Morgan, and M. Eder Gene silencing mediated by small interfering RNAs in mammalian cells Curr. Med. Chem. 10 2003 245 256
    • (2003) Curr. Med. Chem. , vol.10 , pp. 245-256
    • Scherr, M.1    Morgan, M.A.2    Eder, M.3
  • 21
    • 0027751663 scopus 로고
    • The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
    • R.C. Lee, R.L. Feinbaum, and V. Ambros The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14 Cell 75 1993 843 854
    • (1993) Cell , vol.75 , pp. 843-854
    • Lee, R.C.1    Feinbaum, R.L.2    Ambros, V.3
  • 22
    • 0035929322 scopus 로고    scopus 로고
    • A role for the RNase III enzyme DCR-1 in RNA interference and germ line development in Caenorhabditis elegans
    • S.W. Knight, and B.L. Bass A role for the RNase III enzyme DCR-1 in RNA interference and germ line development in Caenorhabditis elegans Science 293 2001 2269 2271
    • (2001) Science , vol.293 , pp. 2269-2271
    • Knight, S.W.1    Bass, B.L.2
  • 23
    • 0035887005 scopus 로고    scopus 로고
    • Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans
    • R.F. Ketting, S.E. Fischer, E. Bernstein, T. Sijen, G.J. Hannon, and R.H. Plasterk Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans Genes Dev. 15 2001 2654 2659
    • (2001) Genes Dev. , vol.15 , pp. 2654-2659
    • Ketting, R.F.1    Fischer, S.E.2    Bernstein, E.3    Sijen, T.4    Hannon, G.J.5    Plasterk, R.H.6
  • 28
  • 29
    • 0037320231 scopus 로고    scopus 로고
    • P1/HC-Pro, a viral suppressor of RNA silencing, interferes with Arabidopsis development and miRNA function
    • K.D. Kasschau, Z. Xie, E. Allen, C. Llave, E.J. Chapman, K.A. Krizan, and J.C. Carrington P1/HC-Pro, a viral suppressor of RNA silencing, interferes with Arabidopsis development and miRNA function Dev. Cell. 4 2003 205 217
    • (2003) Dev. Cell. , vol.4 , pp. 205-217
    • Kasschau, K.D.1    Xie, Z.2    Allen, E.3    Llave, C.4    Chapman, E.J.5    Krizan, K.A.6    Carrington, J.C.7
  • 30
    • 0037144546 scopus 로고    scopus 로고
    • A microRNA in a multiple-turnover RNAi enzyme complex
    • G. Hutvagner, and P.D. Zamore A microRNA in a multiple-turnover RNAi enzyme complex Science 297 2002 2056 2060
    • (2002) Science , vol.297 , pp. 2056-2060
    • Hutvagner, G.1    Zamore, P.D.2
  • 34
    • 0036294527 scopus 로고    scopus 로고
    • Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells
    • Y. Zeng, E.J. Wagner, and B.R. Cullen Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells Mol. Cell. 9 2002 1327 1333
    • (2002) Mol. Cell. , vol.9 , pp. 1327-1333
    • Zeng, Y.1    Wagner, E.J.2    Cullen, B.R.3
  • 37
    • 0142039054 scopus 로고    scopus 로고
    • A DNA target of 30 bp is sufficient for RNA-directed DNA methylation
    • T. Pelissier, and M. Wassenegger A DNA target of 30 bp is sufficient for RNA-directed DNA methylation RNA 6 2000 55 65
    • (2000) RNA , vol.6 , pp. 55-65
    • Pelissier, T.1    Wassenegger, M.2
  • 38
    • 0035077189 scopus 로고    scopus 로고
    • Size constraints for targeting post-transcriptional gene silencing and for RNA-directed methylation in Nicotiana benthamiana using a potato virus X vector
    • C.L. Thomas, L. Jones, D.C. Baulcombe, and A.J. Maule Size constraints for targeting post-transcriptional gene silencing and for RNA-directed methylation in Nicotiana benthamiana using a potato virus X vector Plant J. 25 2001 417 425
    • (2001) Plant J. , vol.25 , pp. 417-425
    • Thomas, C.L.1    Jones, L.2    Baulcombe, D.C.3    Maule, A.J.4
  • 39
    • 0037425622 scopus 로고    scopus 로고
    • Chromatin silencing: RNA in the driving seat
    • D.S. Stevenson, and P. Jarvis Chromatin silencing: RNA in the driving seat Curr. Biol. 13 2003 R13 R15
    • (2003) Curr. Biol. , vol.13
    • Stevenson, D.S.1    Jarvis, P.2
  • 41
    • 1342332038 scopus 로고    scopus 로고
    • RNAi in cultured Drosophila cells
    • L.R. Kao, and T.L. Megraw RNAi in cultured Drosophila cells Methods Mol. Biol. 247 2004 443 457
    • (2004) Methods Mol. Biol. , vol.247 , pp. 443-457
    • Kao, L.R.1    Megraw, T.L.2
  • 42
    • 0037322606 scopus 로고    scopus 로고
    • RNAi: Mammalian oocytes do it without RNA-dependent RNA polymerase
    • P. Stein, P. Svoboda, M. Anger, and R.M. Schultz RNAi: mammalian oocytes do it without RNA-dependent RNA polymerase RNA 9 2003 187 192
    • (2003) RNA , vol.9 , pp. 187-192
    • Stein, P.1    Svoboda, P.2    Anger, M.3    Schultz, R.M.4
  • 43
    • 0035850778 scopus 로고    scopus 로고
    • RNAi in mouse oocytes and preimplantation embryos: Effectiveness of hairpin dsRNA
    • P. Svoboda, P. Stein, and R.M. Schultz RNAi in mouse oocytes and preimplantation embryos: effectiveness of hairpin dsRNA Biochem. Biophys. Res. Commun. 287 2001 1099 1104
    • (2001) Biochem. Biophys. Res. Commun. , vol.287 , pp. 1099-1104
    • Svoboda, P.1    Stein, P.2    Schultz, R.M.3
  • 44
    • 19044381013 scopus 로고    scopus 로고
    • Phenotypic silencing of cytoplasmic genes using sequence-specific double-stranded short interfering RNA and its application in the reverse genetics of wild type negative-strand RNA viruses
    • V. Bitko, and S. Barik Phenotypic silencing of cytoplasmic genes using sequence-specific double-stranded short interfering RNA and its application in the reverse genetics of wild type negative-strand RNA viruses BMC Microbiol. 1 2001 34 40
    • (2001) BMC Microbiol. , vol.1 , pp. 34-40
    • Bitko, V.1    Barik, S.2
  • 45
    • 0037197914 scopus 로고    scopus 로고
    • RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells
    • J.Y. Yu, S.L. DeRuiter, and D.L. Turner RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells Proc. Natl. Acad. Sci. U.S.A. 99 2002 6047 6052
    • (2002) Proc. Natl. Acad. Sci. U.S.A. , vol.99 , pp. 6047-6052
    • Yu, J.Y.1    Deruiter, S.L.2    Turner, D.L.3
  • 46
    • 0036607092 scopus 로고    scopus 로고
    • Reverse genetics of essential genes in tissue-culture cells: 'Dead cells talking'
    • D.F. Hudson, C. Morrison, S. Ruchaud, and W.C. Earnshaw Reverse genetics of essential genes in tissue-culture cells: 'dead cells talking' Trends Cell Biol. 2002 281 287
    • (2002) Trends Cell Biol. , pp. 281-287
    • Hudson, D.F.1    Morrison, C.2    Ruchaud, S.3    Earnshaw, W.C.4
  • 47
    • 0035795428 scopus 로고    scopus 로고
    • RNA interference and small interfering RNAs
    • T. Tuschl RNA interference and small interfering RNAs Chembiochem. 2 2001 239 245
    • (2001) Chembiochem. , vol.2 , pp. 239-245
    • Tuschl, T.1
  • 48
    • 0042319070 scopus 로고    scopus 로고
    • Development and application of siRNA expression vector
    • M. Miyagishi, and K. Taira Development and application of siRNA expression vector Nucleic Acids Res. Suppl. 2002 113 114
    • (2002) Nucleic Acids Res. Suppl. , pp. 113-114
    • Miyagishi, M.1    Taira, K.2
  • 49
    • 24144445346 scopus 로고    scopus 로고
    • Comparison of the suppressive effects of antisense oligonucleotides and siRNAs directed against the same targets in mammalian cells
    • M. Miyagishi, M. Hayashi, and K. Taira Comparison of the suppressive effects of antisense oligonucleotides and siRNAs directed against the same targets in mammalian cells Antisense Nucleic Acid Drug Dev. 13 2003 1 7
    • (2003) Antisense Nucleic Acid Drug Dev. , vol.13 , pp. 1-7
    • Miyagishi, M.1    Hayashi, M.2    Taira, K.3
  • 50
    • 0036811055 scopus 로고    scopus 로고
    • Effects on RNA interference in gene expression (RNAi) in cultured mammalian cells of mismatches and the introduction of chemical modifications at the 3′-ends of siRNAs
    • M. Hamada, T. Ohtsuka, R. Kawaida, M. Koizumi, K. Morita, H. Furukawa, T. Imanishi, M. Miyagishi, and K. Taira Effects on RNA interference in gene expression (RNAi) in cultured mammalian cells of mismatches and the introduction of chemical modifications at the 3′-ends of siRNAs Antisense Nucleic Acid Drug Dev. 12 2002 301 309
    • (2002) Antisense Nucleic Acid Drug Dev. , vol.12 , pp. 301-309
    • Hamada, M.1    Ohtsuka, T.2    Kawaida, R.3    Koizumi, M.4    Morita, K.5    Furukawa, H.6    Imanishi, T.7    Miyagishi, M.8    Taira, K.9
  • 51
    • 0036251639 scopus 로고    scopus 로고
    • Effective expression of small interfering RNA in human cells
    • C.P. Paul, P.D. Good, I. Winer, and D.R. Engelke Effective expression of small interfering RNA in human cells Nat. Biotechnol. 20 2002 505 508
    • (2002) Nat. Biotechnol. , vol.20 , pp. 505-508
    • Paul, C.P.1    Good, P.D.2    Winer, I.3    Engelke, D.R.4
  • 52
    • 24144475882 scopus 로고    scopus 로고
    • Stimulatory effect of an indirectly attached RNA helicase-recruiting sequence on the suppression of gene expression by antisense oligonucleotides
    • T. Futami, M. Miyagishi, S. Iwai, M. Seki, and K. Taira Stimulatory effect of an indirectly attached RNA helicase-recruiting sequence on the suppression of gene expression by antisense oligonucleotides Antisense Nucleic Acid Drug Dev. 13 2003 9 17
    • (2003) Antisense Nucleic Acid Drug Dev. , vol.13 , pp. 9-17
    • Futami, T.1    Miyagishi, M.2    Iwai, S.3    Seki, M.4    Taira, K.5
  • 53
    • 0042091934 scopus 로고    scopus 로고
    • Targeting mortalin using conventional and RNA-helicase-coupled hammerhead ribozymes
    • R. Wadhwa, H. Ando, H. Kawasaki, K. Taira, and S.C. Kaul Targeting mortalin using conventional and RNA-helicase-coupled hammerhead ribozymes EMBO Rep. 4 2003 595 601
    • (2003) EMBO Rep. , vol.4 , pp. 595-601
    • Wadhwa, R.1    Ando, H.2    Kawasaki, H.3    Taira, K.4    Kaul, S.C.5
  • 54
    • 0042704947 scopus 로고    scopus 로고
    • Discovery of functional genes in the post-genome era by novel RNA-protein hybrid ribozymes
    • H. Kawasaki, and K. Taira Discovery of functional genes in the post-genome era by novel RNA-protein hybrid ribozymes Nucleic Acids Res. Suppl. 2001 133 134
    • (2001) Nucleic Acids Res. Suppl. , pp. 133-134
    • Kawasaki, H.1    Taira, K.2
  • 55
    • 0036245628 scopus 로고    scopus 로고
    • U6 promoter-driven siRNAs with four uridine 3′ overhangs efficiently suppress targeted gene expression in mammalian cells
    • M. Miyagishi, and K. Taira U6 promoter-driven siRNAs with four uridine 3′ overhangs efficiently suppress targeted gene expression in mammalian cells Nat. Biotechnol. 20 2002 497 500
    • (2002) Nat. Biotechnol. , vol.20 , pp. 497-500
    • Miyagishi, M.1    Taira, K.2
  • 56
    • 0037440160 scopus 로고    scopus 로고
    • Short hairpin type of dsRNAs that are controlled by tRNA(Val) promoter significantly induce RNAi-mediated gene silencing in the cytoplasm of human cells
    • H. Kawasaki, and K. Taira Short hairpin type of dsRNAs that are controlled by tRNA(Val) promoter significantly induce RNAi-mediated gene silencing in the cytoplasm of human cells Nucleic Acids Res. 31 2003 700 707
    • (2003) Nucleic Acids Res. , vol.31 , pp. 700-707
    • Kawasaki, H.1    Taira, K.2
  • 57
  • 58
    • 0037213559 scopus 로고    scopus 로고
    • Mammalian RNAi for the masses
    • Y. Shi Mammalian RNAi for the masses Trends Genet. 19 2003 9 12
    • (2003) Trends Genet. , vol.19 , pp. 9-12
    • Shi, Y.1
  • 59
    • 0142150130 scopus 로고    scopus 로고
    • Control of siRNA expression utilizing Cre-loxP recombination system
    • V. Kasim, M. Miyagishi, and K. Taira Control of siRNA expression utilizing Cre-loxP recombination system Nucleic Acids Res. Suppl. 2003 255 256
    • (2003) Nucleic Acids Res. Suppl. , pp. 255-256
    • Kasim, V.1    Miyagishi, M.2    Taira, K.3
  • 61
    • 13644269779 scopus 로고    scopus 로고
    • Optimization of an siRNA-expression system with a mutated hairpin and its significant suppressive effects upon HIV vector-mediated transfer into mammalian cell
    • M. Miyagishi, H. Sunimoto, H. Miyoshi, Y. Kawakami, and K. Taira Optimization of an siRNA-expression system with a mutated hairpin and its significant suppressive effects upon HIV vector-mediated transfer into mammalian cell J. Gene Med. 6 2004 715 723
    • (2004) J. Gene Med. , vol.6 , pp. 715-723
    • Miyagishi, M.1    Sunimoto, H.2    Miyoshi, H.3    Kawakami, Y.4    Taira, K.5
  • 62
    • 0037440160 scopus 로고    scopus 로고
    • Short hairpin type of dsRNAs that are controlled by tRNA(Val) promoter significantly induce RNAi-mediated gene silencing in the cytoplasm of human cells
    • H. Kawasaki, and K. Taira Short hairpin type of dsRNAs that are controlled by tRNA(Val) promoter significantly induce RNAi-mediated gene silencing in the cytoplasm of human cells Nucleic Acids Res. 31 2003 700 707
    • (2003) Nucleic Acids Res. , vol.31 , pp. 700-707
    • Kawasaki, H.1    Taira, K.2
  • 63
    • 0036787671 scopus 로고    scopus 로고
    • SiRNA-mediated gene silencing in vitro and in vivo
    • H. Xia, Q. Mao, H.L. Paulson, and B.L. Davidson siRNA-mediated gene silencing in vitro and in vivo Nat. Biotechnol. 20 2002 1006 1010
    • (2002) Nat. Biotechnol. , vol.20 , pp. 1006-1010
    • Xia, H.1    Mao, Q.2    Paulson, H.L.3    Davidson, B.L.4
  • 64
    • 1642482665 scopus 로고    scopus 로고
    • Expression of siRNA from a single transcript that includes multiple ribozymes in mammalian cells
    • Y. Kato, and K. Taira Expression of siRNA from a single transcript that includes multiple ribozymes in mammalian cells Oligonucleotides 13 2003 335 343
    • (2003) Oligonucleotides , vol.13 , pp. 335-343
    • Kato, Y.1    Taira, K.2
  • 65
    • 0037948173 scopus 로고    scopus 로고
    • Generation of Ski-knock down mice by expressing a long double-strand RNA from an RNA polymerase II promoter
    • T. Shinagawa, and S. Ishii Generation of Ski-knock down mice by expressing a long double-strand RNA from an RNA polymerase II promoter Genes Dev. 17 2003 1340 1345
    • (2003) Genes Dev. , vol.17 , pp. 1340-1345
    • Shinagawa, T.1    Ishii, S.2
  • 68
    • 0037452812 scopus 로고    scopus 로고
    • A general method for gene knock down in mice by using lentiviral vectors expressing small interfering RNA
    • G. Tiscornia, O. Singer, M. Ikawa, and I.M. Verma A general method for gene knock down in mice by using lentiviral vectors expressing small interfering RNA Proc. Natl. Acad. Sci. U.S.A. 100 2003 1844 1848
    • (2003) Proc. Natl. Acad. Sci. U.S.A. , vol.100 , pp. 1844-1848
    • Tiscornia, G.1    Singer, O.2    Ikawa, M.3    Verma, I.M.4
  • 69
    • 0242317385 scopus 로고    scopus 로고
    • Small RNA: Can RNA interference be exploited for therapy?
    • N.R. Wall, and Y. Shi Small RNA: can RNA interference be exploited for therapy? Lancet 362 2003 1401 1403
    • (2003) Lancet , vol.362 , pp. 1401-1403
    • Wall, N.R.1    Shi, Y.2
  • 70
    • 0142259345 scopus 로고    scopus 로고
    • New tools for functional mammalian cancer genetics
    • T.R. Brummelkamp, and R. Bernards New tools for functional mammalian cancer genetics Nat. Rev. Cancer 3 2003 781 789
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 781-789
    • Brummelkamp, T.R.1    Bernards, R.2
  • 71
    • 0037422583 scopus 로고    scopus 로고
    • Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5
    • X.F. Qin, D.S. An, I.S. Chen, and D. Baltimore Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5 Proc. Natl. Acad. Sci. U.S.A. 100 2003 183 188
    • (2003) Proc. Natl. Acad. Sci. U.S.A. , vol.100 , pp. 183-188
    • Qin, X.F.1    An, D.S.2    Chen, I.S.3    Baltimore, D.4
  • 73
    • 0037080675 scopus 로고    scopus 로고
    • Regulation of ATR substrate selection by Radl7-dependent loading of Rad9 complexes onto chromatin
    • L. Zou, D. Cortez, and S.J. Elledge Regulation of ATR substrate selection by Radl7-dependent loading of Rad9 complexes onto chromatin Genes Dev. 16 2002 198 208
    • (2002) Genes Dev. , vol.16 , pp. 198-208
    • Zou, L.1    Cortez, D.2    Elledge, S.J.3
  • 75
    • 0037151042 scopus 로고    scopus 로고
    • Methyl-CpG binding domain protein 2 represses transcription from hypermethylated pi-class glutathione S-transferase gene promoters in hepatocellular carcinoma cells
    • J. Bakker, X. Lin, and W.G. Nelson Methyl-CpG binding domain protein 2 represses transcription from hypermethylated pi-class glutathione S-transferase gene promoters in hepatocellular carcinoma cells J. Biol. Chem. 277 2002 22573 22580
    • (2002) J. Biol. Chem. , vol.277 , pp. 22573-22580
    • Bakker, J.1    Lin, X.2    Nelson, W.G.3
  • 77
    • 0041705337 scopus 로고    scopus 로고
    • A new view on p53 protein cytoplasmic sequestration
    • S. Douc-Rasy, and J. Benard A new view on p53 protein cytoplasmic sequestration Bull. Cancer 90 2003 380 382
    • (2003) Bull. Cancer , vol.90 , pp. 380-382
    • Douc-Rasy, S.1    Benard, J.2
  • 78
    • 0142157679 scopus 로고    scopus 로고
    • Maxizymes and small hairpin-type RNAs that are driven by a tRNA promoter specifically cleave a chimeric gene associated with leukemia in vitro and in vivo
    • K. Oshima, H. Kawasaki, Y. Soda, K. Tani, S. Asano, and K. Taira Maxizymes and small hairpin-type RNAs that are driven by a tRNA promoter specifically cleave a chimeric gene associated with leukemia in vitro and in vivo Cancer Res. 63 2003 6809 6814
    • (2003) Cancer Res. , vol.63 , pp. 6809-6814
    • Oshima, K.1    Kawasaki, H.2    Soda, Y.3    Tani, K.4    Asano, S.5    Taira, K.6
  • 79
    • 0347904503 scopus 로고    scopus 로고
    • Inhibition of telomerase activity in human cancer cells by RNA interference
    • B.A. Kosciolek, K. Kalantidis, M. Tabler, and P.T. Rowley Inhibition of telomerase activity in human cancer cells by RNA interference Mol. Cancer Ther. 2 2003 209 216
    • (2003) Mol. Cancer Ther. , vol.2 , pp. 209-216
    • Kosciolek, B.A.1    Kalantidis, K.2    Tabler, M.3    Rowley, P.T.4
  • 84
    • 0033789992 scopus 로고    scopus 로고
    • Specific interference with gene function by double-stranded RNA in early mouse development
    • F. Wianny, and M. Zernicka-Goetz Specific interference with gene function by double-stranded RNA in early mouse development Nat. Cell Biol. 2 2000 70 75
    • (2000) Nat. Cell Biol. , vol.2 , pp. 70-75
    • Wianny, F.1    Zernicka-Goetz, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.