MicroRNAs: Hidden in the genome

Current Biology

Volumn 12, Issue 4, 2002, Pages

  Moss, Eric G ^a  

^a FOX CHASE CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA;

COMPLEMENTARY RNA; DOUBLE STRANDED RNA; MICRORNA; UNTRANSLATED RNA;

ANIMAL; DNA BASE COMPOSITION; GENE EXPRESSION REGULATION; GENETICS; GENOME; HUMAN; METABOLISM; MOLECULAR EVOLUTION; NUCLEOTIDE SEQUENCE; REVIEW;

ANIMALS; BASE COMPOSITION; BASE SEQUENCE; EVOLUTION, MOLECULAR; GENE EXPRESSION REGULATION; GENOME; HUMANS; MICRORNAS; RNA, ANTISENSE; RNA, DOUBLE-STRANDED; RNA, UNTRANSLATED;

EID: 0037133225     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(02)00708-X     Document Type: Review

References (20)

1. Identification of novel genes coding for small expressed RNAs
2. An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans
3. An extensive class of small RNAs in Caenorhabditis elegans
4. Mutations that lead to reiterations in the cell lineage of C. elegans
5. The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans
6. Control of developmental timing in Caenorhabditis elegans
7. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
8. Posttranscriptional regulation of the heterochronic gene lin-14 by lin- 4 mediates temporal pattern formation in C. elegans
9. The cold shock domain protein LIN-28 controls developmental timing in C. elegans and is regulated by the lin-4 RNA
10. The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor
11. The lin-4 regulatory RNA controls developmental timing in Caenorhabditis elegans by blocking LIN-14 protein synthesis after the initiation of translation
12. Two genetic circuits repress the C. elegans heterochronic gene lin-28 after translation initiation
13. Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA
14. Noncoding RNA genes
15. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
16. RNA interference: Listening to the sound of silence
17. RNAi as Random Degradative PCR. siRNA primers convert mRNA into dsRNAs that are degraded to generate new siRNAs
18. Role for a bidentate ribonuclease in the initiation step of RNA interference
19. Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing
20. A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA