UV Induces Phosphorylation of Protein Kinase B (Akt) at Ser-473 and Thr-308 in Mouse Epidermal Cl 41 Cells through Hydrogen Peroxide

Journal of Biological Chemistry

Volumn 276, Issue 43, 2001, Pages 40234-40240

  Huang, Chuanshu ^a   Li, Jingxia ^a   Ding, Min ^b   Leonard, Stephen S ^b   Wang, Liying ^b   Castranova, Vincent ^b   Vallyathan, Val ^b   Shi, Xianglin ^b  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASSAYS; CARCINOGENS; CELLS; FLUORESCENCE; HYDROGEN PEROXIDE; ULTRAVIOLET RADIATION;

PHOSPHORYLATION;

PROTEINS;

ACETYLCYSTEINE; ANTIOXIDANT; CATALASE; FORMATE SODIUM; HYDROGEN PEROXIDE; OXYGEN; PROTEIN KINASE; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; SCAVENGER; SERINE; SUPEROXIDE DISMUTASE; THREONINE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; FLAVONOID; MITOGEN ACTIVATED PROTEIN KINASE; ONCOPROTEIN; PROTEIN SERINE THREONINE KINASE;

ANIMAL CELL; ARTICLE; CARCINOGENESIS; CONTROLLED STUDY; ELECTRON SPIN RESONANCE; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME PHOSPHORYLATION; EPIDERMIS CELL; FLUORESCENCE; GENE OVEREXPRESSION; MAMMAL CELL; MEASUREMENT; NONHUMAN; PRIORITY JOURNAL; REDUCTION; SUN EXPOSURE; ULTRAVIOLET RADIATION; ANIMAL; CYTOLOGY; EPIDERMIS; METABOLISM; MOUSE; PHOSPHORYLATION; RADIATION EXPOSURE; SIGNAL TRANSDUCTION;

ANIMALIA; MAMMALIA;

ANIMALS; EPIDERMIS; FLAVONOIDS; FREE RADICAL SCAVENGERS; HYDROGEN PEROXIDE; MAP KINASE SIGNALING SYSTEM; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; REACTIVE OXYGEN SPECIES; SERINE; THREONINE; ULTRAVIOLET RAYS;

EID: 0035955722     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M103684200     Document Type: Article

References (51)

1. Parrish, J. A. (1993) in Biochemistry and Physiology of the Skin (Goldsmith, L. A., ed) Vol. II, pp. 713-333, Oxford University Press, New York
2. Strickland, P. T. (1986) J. Invest. Dermatol. 87, 272-275
3. Staberg, B., Wolf, H. C., Klemp, P., Poulsen, T., and Bradhagen, H. (1983) J. Invest. Dermatol. 81, 517-519
4. Steidl, M., and Deleo, V. A. (1990) Carcinogenesis 11, 229-234
5. Devary, Y. (1991) Mol. Cell. Biol. 11, 2804-2811
6. Ronai, Z., and Weinstein, I. B. (1988) J. Virol. 62, 1057-1060
7. Huang, C., Ma, W.-Y., Maxiner, A, Sun, Y., and Dong, Z. (1999) J. Biol. Chem. 274, 12229-12235
8. Huang, C., Ma, W.-Y., Ryan, C. A., and Dong, Z. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 11957-11962
9. Angel, P. (1995) in Induced Gene Expression (Baeuerle, P. A., ed) pp. 63-92, Birkhäuser, Boston, MA
10. Shea, C. R., and Parrish, J. A. (1991) in Physiology, Biochemistry, and Molecular Biology of the Skin (Goldsmith, L. A., ed), pp. 910-927, Oxford University Press, New York
11. Devary, Y., Gottlieb, R. A., Smeal, T., and Karin, M. (1992) Cell 71, 1081-1091
12. Radler-Pohl, A., Sachsenmaier, C., Gebel, S., Auer, H.-P., Bruder, J. T., Rapp, U., Angel, P., Rahmsdorf, H. J., and Herrlich, P. (1993) EMBO J. 12, 1005-1012
13. Derijard, B. Hibi, M., Wu, I.-H., Barret, T., Su, B., Deng, T., Karin, M., and Davis, R. J. (1994) Cell 76, 1025-1037
14. Devary, Y., Rosette, C., DiDonato, J. A., and Karin, M. (1993) Science 261, 1442-1445
15. Huang, C., Ma, W.-Y., Bowden, G. T., and Dong, Z. (1996) J. Biol. Chem. 271, 31262-31268
16. Huang, C., Ma, W.-Y., and Dong, Z. (1997) Oncogene 14, 1945-1954
17. Huang, C., Li, J., Chen, N., Ma, W.-Y., Bowden, G. T., and Dong, Z. (2000) Mol. Carcinog. 27, 65-75
18. Staal, S. P. (1987) Proc. Natl. Acad. Sci. U. S. A. 84, 5034-5037
19. Bellacosa, A., Testa, J. R., Staal, S. P., and Tsichlis, P. N. (1991) Science 254, 274-277
20. Bellacosa, A., Franke, T. F., Gonzalez-Portal, M. E., Datta, K., Taguchi, T., Gardner, J., Cheng, J. Q., Testa, J. R., and Tsichlis, P. N. (1993) Oncogene 8, 745-754
21. Datta, S. R., Brunet, A., and Greenberg, M. E. (1999) Genes Dev. 15, 2905-2927
22. Mayer, B. J., Ren, R., Clark, K. L., and Baltimore, D. (1993) Cell 73, 629-630
23. Musacchio, A., Gibson, T., Rice, P., Thompson, J., and Saraste, M. (1993) Trends Biochem. Sci 18, 343-348
24. Burgering, B. M., and Coffer, P. J. (1995) Nature 376, 599-602
25. Franke, T. F., Yang, S. I., Chan, T. O., Datta, K., Kazlauskas, A., Morrison, D. K., Kaplan, D. R., and Tsichlis, P. N. (1995) Cell 81, 727-736
26. Alessi, D. R., Andjelkovic, M., Caudwell, B., Cron, P., Morrice, N., Cohen, P., and Hemmings, B. A. (1996) EMBO J. 15, 6541-6551
27. Jiang, B. H., Aoki, M., Zheng, J. Z., Li, J., and Vogt, P. K. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 2077-2081
28. Huang, C., Ma, W.-Y., and Dong, Z. (1999) Carcinogenesis 20, 237-242
29. Ye, J.-P., Wang, S., Leonard, S. S., Sun, Y., Butterworth, L., Antonini, J., Ding, M., Rojanasakul, Y., Vallyathan, V., Castranova, V., and Shi, X. (1999) J. Biol. Chem. 274, 34974-34980
30. Shi, X., and Dalal, N. S. (1992) Free Radic. Res. Commun. 17, 369-376
31. Huang, C., Ma, W.-Y., Hanenberger, D., Cleary, M. P., Bowden, G. T., and Dong, Z. (1997) J. Biol. Chem. 272, 26325-26331
32. Harbour, J. R., Chow, V., and Bolton, J. R. (1974) Can. J. Chem. 52, 3549-3553
33. Wang, X., McCullough, K. D., Franke, T. F., and Holbrook, N. J. (2000) J. Biol. Chem. 275, 14624-14631
34. Sonoda, Y., Watanabe, S., Matsumoto, Y., Aizu-Yokota, E., and Kasahara, T. (1999) J. Biol. Chem. 274, 10566-10570
35. Tyrrell, R. M. (1996) Bioessays 18, 139-148
36. Lander, H. M. (1997) FASEB J. 11, 118-124
37. Sen, C. K., and Packer, L. (1996) FASEB J. 10, 709-720
38. Sundaresan, M., Yu, Z.-X., Ferrans, V. J., Irani, K., and Finkel, T. (1995) Science 270, 296-299
39. James, S. R., Downes, C. P., Gigg, R., Grove, S. J., Holmes, A. B., and Alessi, D. R. (1996) Biochem. J. 315, 709-713
40. Franke, T. F., Kaplan, D. R., Cantley, L. C., and Toker, A. (1997) Science 275, 665-666
41. Frech, M., Andjelkovic, M., Ingley, E., Reddy, K. K., Falck, J. R., and Hemmings, B. A. (1997) J. Biol. Chem. 272, 8474-8481
42. Klippel, A., Kavanaugh, W. M., Pot, D., and Williams, L. T. (1997) Mol. Cell. Biol. 17, 338-344
43. Sable, C. L., Filippa, N., Hemmings, B., and Van Obberghen, E. (1997) FEBS Lett. 409, 253-257
44. Filippa, N., Sable, C. L., Filloux, C., Hemmings, B., and Van Obberghen, E. (1999) Mol. Cell. Biol. 19, 4989-5000
45. Yano, S., Tokumitsu, H., and Soderling, T. R. (1998) Nature 396, 584-587
46. Huang, C., Mattjus, P., Ma, W.-Y., Rincon, M., Chen, N. Y., Brown, R. E., and Dong, Z. (2000) J. Biol. Chem. 275, 9143-9149
47. Chang, H. W., Aoki, M., Fruman, D., Auger, K. R., Bellacosa, A., Tsichlis, P. N., Cantley, L. C., Roberts, T. M., and Vogt, P. K. (1997) Science 276, 1848-1850
48. Aoki, M., Batista, O., Bellacosa, A., Tsichlis, P., and Vogt, P. K. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 14950-14955
49. Skorski, T., Bellacosa, A., Nieborowska-Skorska, M., Majewski, M., Martinez, R., Choi, J. K., Trotta, R., Wlodarski, P., Perrotti, D., Chan, T. O., Wasik, M. A., Tsichlis, P. N., and Calabretta, B. (1997) EMBO J. 16, 6151-6161
50. Bellacosa, A., de Feo, D., Godwin, A. K., Bell, D. W., Cheng, J. Q., Altomare, D. A., Wan, M. H., Dubeau, L., Scambia, G., Masciullo, V., Ferrandina, G., Panici, P. B., Mancuso, S., Neri, G., and Testa, J. R. (1995) Int. J. Cancer 64, 280-285
51. Cheng, J. Q., Ruggeri, B., Klein, W. M., Sonoda, G., Altomare, D. A., Watson, D. K., and Testa, J. R. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 3636-3641