메뉴 건너뛰기




Volumn 17, Issue 1, 2003, Pages 101-114

The highly conserved Ndc80 complex is required for kinetochore assembly, chromosome congression, and spindle checkpoint activity

Author keywords

Cell cycle; Centromere; Chromosome segregation; Kinetochore; Mitosis; Spindle checkpoint

Indexed keywords

BLOCKING ANTIBODY; BUB3 PROTEIN; DYNACTIN; PROTEIN BUB1; PROTEIN DERIVATIVE; PROTEIN MAD1; PROTEIN MAD2; PROTEIN NDC80; PROTEIN NUF2; PROTEIN P 150; PROTEIN ROD; PROTEIN ZW10; UNCLASSIFIED DRUG;

EID: 0037227023     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.1040903     Document Type: Article
Times cited : (220)

References (47)
  • 1
    • 0021355377 scopus 로고
    • Relationship of actin and tubulin distribution to bud growth in wild-type and morphogenetic-mutant Saccharomyces cerevisiae
    • Adams, A.E. and Pringle, J.R. 1984. Relationship of actin and tubulin distribution to bud growth in wild-type and morphogenetic-mutant Saccharomyces cerevisiae. J. Cell Biol. 98: 934-945.
    • (1984) J. Cell Biol. , vol.98 , pp. 934-945
    • Adams, A.E.1    Pringle, J.R.2
  • 2
    • 0033662264 scopus 로고    scopus 로고
    • Rough Deal and Zw10 are required for the metaphase checkpoint in Drosophila
    • Basto, R., Gomes, R., and Karess, R. E. 2000. Rough Deal and Zw10 are required for the metaphase checkpoint in Drosophila. Nat. Cell Biol. 2: 939-943.
    • (2000) Nat. Cell Biol. , vol.2 , pp. 939-943
    • Basto, R.1    Gomes, R.2    Karess, R.E.3
  • 3
    • 0036732808 scopus 로고    scopus 로고
    • Aurora B kinase exists in a complex with Survivin and INCENP and its kinase activity is stimulated by Survivin binding and phosphorylation
    • Bolton, M.A., Lan, W., Powers, S.E., McCleland, M.L., Kuang, J., and Stukenberg, P.T. 2002. Aurora B kinase exists in a complex with Survivin and INCENP and its kinase activity is stimulated by Survivin binding and phosphorylation. Mol. Biol. Cell 13: 3064-3077.
    • (2002) Mol. Biol. Cell , vol.13 , pp. 3064-3077
    • Bolton, M.A.1    Lan, W.2    Powers, S.E.3    McCleland, M.L.4    Kuang, J.5    Stukenberg, P.T.6
  • 4
    • 0027483798 scopus 로고
    • MIF2 is required for mitotic spindle integrity during anaphase spindle elongation in Saccharomyces cerevisiae
    • Brown, M.T., Goetsch, L., and Hartwell, L.H. 1993. MIF2 is required for mitotic spindle integrity during anaphase spindle elongation in Saccharomyces cerevisiae. J. Cell Biol. 123: 387-403.
    • (1993) J. Cell Biol. , vol.123 , pp. 387-403
    • Brown, M.T.1    Goetsch, L.2    Hartwell, L.H.3
  • 5
    • 0033672239 scopus 로고    scopus 로고
    • Human Zw10 and ROD are mitotic checkpoint proteins that bind to kinetochores
    • Chan, G.K.T., Jablonski, S.A., Starr, D.A., Goldberg, M.L., and Yen, T.J. 2000. Human Zw10 and ROD are mitotic checkpoint proteins that bind to kinetochores. Nat. Cell Biol. 2: 944-947.
    • (2000) Nat. Cell Biol. , vol.2 , pp. 944-947
    • Chan, G.K.T.1    Jablonski, S.A.2    Starr, D.A.3    Goldberg, M.L.4    Yen, T.J.5
  • 7
    • 0037092041 scopus 로고    scopus 로고
    • Simple centromere, complex kinetochore: Linking spindle microtubules and centromeric DNA in budding yeast
    • Cheeseman, I.M., Drubin, D.G., and Barnes, G. 2002. Simple centromere, complex kinetochore: Linking spindle microtubules and centromeric DNA in budding yeast. J. Cell Biol. 157: 199-203.
    • (2002) J. Cell Biol. , vol.157 , pp. 199-203
    • Cheeseman, I.M.1    Drubin, D.G.2    Barnes, G.3
  • 8
    • 0032547733 scopus 로고    scopus 로고
    • Spindle checkpoint protein Xmadl recruits Xmad2 to unattached kinetochores
    • Chen, R.H., Shevchenko, A., Mann, M., and Murray, A.W. 1998. Spindle checkpoint protein Xmadl recruits Xmad2 to unattached kinetochores. J. Cell Biol. 143: 283-295.
    • (1998) J. Cell Biol. , vol.143 , pp. 283-295
    • Chen, R.H.1    Shevchenko, A.2    Mann, M.3    Murray, A.W.4
  • 9
    • 0030864009 scopus 로고    scopus 로고
    • HEC, a novel nuclear protein rich in leucine heptad repeats specifically involved in mitosis
    • Chen, Y., Riley, D.J., Chen, P.L., and Lee, W.H. 1997. HEC, a novel nuclear protein rich in leucine heptad repeats specifically involved in mitosis. Mol. Cell. Biol. 17: 6049-6056.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 6049-6056
    • Chen, Y.1    Riley, D.J.2    Chen, P.L.3    Lee, W.H.4
  • 10
    • 0004002022 scopus 로고    scopus 로고
    • Oxford University Press, New York
    • Choo, A. 1997. The centromere. Oxford University Press, New York.
    • (1997) The Centromere
    • Choo, A.1
  • 11
    • 0023580316 scopus 로고
    • The inner centromere protein (INCENP) antigens: Movement from inner centromere to midbody during mitosis
    • Cooke, C.A., Heck, M.M., and Earnshaw, W.C. 1987. The inner centromere protein (INCENP) antigens: Movement from inner centromere to midbody during mitosis. J. Cell Biol. 105: 2053-2067.
    • (1987) J. Cell Biol. , vol.105 , pp. 2053-2067
    • Cooke, C.A.1    Heck, M.M.2    Earnshaw, W.C.3
  • 12
    • 0028213449 scopus 로고
    • Heat-inducible degron: A method for constructing temperature-sensitive mutants
    • Dohmen, R.J., Wu, P., and Varshavsky, A. 1994. Heat-inducible degron: A method for constructing temperature-sensitive mutants. Science 263: 1273-1276.
    • (1994) Science , vol.263 , pp. 1273-1276
    • Dohmen, R.J.1    Wu, P.2    Varshavsky, A.3
  • 14
    • 0021989578 scopus 로고
    • Identification of a family of human centromere proteins using autoimmune sera from patients with scleroderma
    • Earnshaw, W.C. and Rothfield, N. 1985. Identification of a family of human centromere proteins using autoimmune sera from patients with scleroderma. Chromosoma 91: 313-321.
    • (1985) Chromosoma , vol.91 , pp. 313-321
    • Earnshaw, W.C.1    Rothfield, N.2
  • 15
    • 0034177830 scopus 로고    scopus 로고
    • The spindle checkpoint: Two transitions, two pathways
    • Gardner, R.D. and Burke, D.J. 2000. The spindle checkpoint: Two transitions, two pathways. Trends Cell Biol. 10: 154-158.
    • (2000) Trends Cell Biol. , vol.10 , pp. 154-158
    • Gardner, R.D.1    Burke, D.J.2
  • 16
    • 0035044554 scopus 로고    scopus 로고
    • The spindle checkpoint of the yeast Saccharomyces cerevisiae requires kinetochore function and maps to the CBF3 domain
    • Gardner, R.D., Poddar, A., Yellman, C., Tavormina, P.A., Monteagudo, M.C., and Burke, D.J. 2001. The spindle checkpoint of the yeast Saccharomyces cerevisiae requires kinetochore function and maps to the CBF3 domain. Genetics 157: 1493-1502.
    • (2001) Genetics , vol.157 , pp. 1493-1502
    • Gardner, R.D.1    Poddar, A.2    Yellman, C.3    Tavormina, P.A.4    Monteagudo, M.C.5    Burke, D.J.6
  • 17
    • 0003448569 scopus 로고
    • Cold Spring Harbor Laboratory, Cold Spring Harbor, New York
    • Harlow, E. and Lane, D. 1988. Antibodies: A laboratory manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, New York.
    • (1988) Antibodies: A Laboratory Manual
    • Harlow, E.1    Lane, D.2
  • 18
    • 0014086848 scopus 로고
    • Macromolecule synthesis in temperaturesensitive mutants of yeast
    • Hartwell, L.H. 1967. Macromolecule synthesis in temperaturesensitive mutants of yeast. J. Bacteriol. 93: 1662-1670.
    • (1967) J. Bacteriol. , vol.93 , pp. 1662-1670
    • Hartwell, L.H.1
  • 19
    • 0035958556 scopus 로고    scopus 로고
    • Molecular analysis of kinetochore-microtubule attachment in budding yeast
    • He, X., Rines, D.R., Espelin, C.W., and Sorger, P.K. 2001. Molecular analysis of kinetochore-microtubule attachment in budding yeast. Cell 106: 195-206.
    • (2001) Cell , vol.106 , pp. 195-206
    • He, X.1    Rines, D.R.2    Espelin, C.W.3    Sorger, P.K.4
  • 20
    • 0035844875 scopus 로고    scopus 로고
    • HIM-10 is required for kinetochore structure and function on Caenorhabditis elegans holocentric chromosomes
    • Howe, M., McDonald, K.L., Albertson, D.G., and Meyer, B.J. 2001. HIM-10 is required for kinetochore structure and function on Caenorhabditis elegans holocentric chromosomes. J. Cell Biol. 153: 1227-1238.
    • (2001) J. Cell Biol. , vol.153 , pp. 1227-1238
    • Howe, M.1    McDonald, K.L.2    Albertson, D.G.3    Meyer, B.J.4
  • 21
    • 0034683744 scopus 로고    scopus 로고
    • Visualization of Mad2 dynamics at kinetochores, along spindle fibers, and at spindle poles in living cells
    • Howell, B.J., Hoffman, D.B., Fang, G., Murray, A.W., and Salmon, E.D. 2000. Visualization of Mad2 dynamics at kinetochores, along spindle fibers, and at spindle poles in living cells. J. Cell Biol. 150: 1233-1250.
    • (2000) J. Cell Biol. , vol.150 , pp. 1233-1250
    • Howell, B.J.1    Hoffman, D.B.2    Fang, G.3    Murray, A.W.4    Salmon, E.D.5
  • 22
    • 0025941405 scopus 로고
    • S. cerevisiae genes required for cell cycle arrest in response to loss of microtubule function
    • Hoyt, M.A., Totis, L., and Roberts, B.T. 1991. S. cerevisiae genes required for cell cycle arrest in response to loss of microtubule function. Cell 66: 507-517.
    • (1991) Cell , vol.66 , pp. 507-517
    • Hoyt, M.A.1    Totis, L.2    Roberts, B.T.3
  • 23
    • 0035865139 scopus 로고    scopus 로고
    • The budding yeast proteins Spc24p and Spc25p interact with Ndc80p and Nuf2p at the kinetochore and are important for kinetochore clustering and checkpoint control
    • Janke, C., Ortiz, J., Lechner, J., Shevchenko, A., Magiera, M.M., Schramm, C., and Schiebel, E. 2001. The budding yeast proteins Spc24p and Spc25p interact with Ndc80p and Nuf2p at the kinetochore and are important for kinetochore clustering and checkpoint control. EMBO J. 20: 777-791.
    • (2001) EMBO J. , vol.20 , pp. 777-791
    • Janke, C.1    Ortiz, J.2    Lechner, J.3    Shevchenko, A.4    Magiera, M.M.5    Schramm, C.6    Schiebel, E.7
  • 24
    • 0037080986 scopus 로고    scopus 로고
    • Four new subunits of the Daml-Duol complex reveal novel functions in sister kinetochore biorientation
    • Janke, C., Ortiz, J., Tanaka, T.U., Lechner, J., and Schiebel, E. 2002. Four new subunits of the Daml-Duol complex reveal novel functions in sister kinetochore biorientation. EMBO J. 21: 181-193.
    • (2002) EMBO J. , vol.21 , pp. 181-193
    • Janke, C.1    Ortiz, J.2    Tanaka, T.U.3    Lechner, J.4    Schiebel, E.5
  • 25
    • 0032837198 scopus 로고    scopus 로고
    • Yeast Damlp is required to maintain spindle integrity during mitosis and interacts with the Mpslp kinase
    • Jones, M.H., Bachant, J.B., Castillo, A.R., Giddings Jr., T.H., and Winey, M. 1999. Yeast Damlp is required to maintain spindle integrity during mitosis and interacts with the Mpslp kinase. Mol. Biol. Cell 10: 2377-2391.
    • (1999) Mol. Biol. Cell , vol.10 , pp. 2377-2391
    • Jones, M.H.1    Bachant, J.B.2    Castillo, A.R.3    Giddings T.H., Jr.4    Winey, M.5
  • 26
    • 0037009056 scopus 로고    scopus 로고
    • Rapid microtubule-independent dynamics of Cdc20 at kinetochores and centrosomes in mammalian cells
    • Kallio, M.J., Beardmore, V.A., Weinstein, J., and Gorbsky, G.J. 2002. Rapid microtubule-independent dynamics of Cdc20 at kinetochores and centrosomes in mammalian cells. J. Cell Biol. 158: 841-847.
    • (2002) J. Cell Biol. , vol.158 , pp. 841-847
    • Kallio, M.J.1    Beardmore, V.A.2    Weinstein, J.3    Gorbsky, G.J.4
  • 28
    • 0026009964 scopus 로고
    • Feedback control of mitosis in budding yeast
    • Li, R. and Murray, A.W. 1991. Feedback control of mitosis in budding yeast. Cell 66: 519-531.
    • (1991) Cell , vol.66 , pp. 519-531
    • Li, R.1    Murray, A.W.2
  • 29
    • 0037080488 scopus 로고    scopus 로고
    • The mitotic spindle is required for loading of the DASH complex onto the kinetochore
    • Li, Y., Bachant, J., Alcasabas, A.A., Wang, Y., Qin, J., and Elledge, S.J. 2002. The mitotic spindle is required for loading of the DASH complex onto the kinetochore. Genes & Dev. 16: 183-197.
    • (2002) Genes & Dev. , vol.16 , pp. 183-197
    • Li, Y.1    Bachant, J.2    Alcasabas, A.A.3    Wang, Y.4    Qin, J.5    Elledge, S.J.6
  • 30
    • 0026356891 scopus 로고
    • Predicting coiled coils from protein sequences
    • Lupas, A., Van Dyke, M., and Stock, J. 1991. Predicting coiled coils from protein sequences. Science 252: 1162-1164.
    • (1991) Science , vol.252 , pp. 1162-1164
    • Lupas, A.1    Van Dyke, M.2    Stock, J.3
  • 31
    • 0037183886 scopus 로고    scopus 로고
    • Role of hecl in spindle checkpoint signaling and kinetochore recruitment of mad1/mad2
    • Martin-Lluesma, S., Stucke, V.M., and Nigg, E.A. 2002. Role of hecl in spindle checkpoint signaling and kinetochore recruitment of mad1/mad2. Science 297: 2267-2270.
    • (2002) Science , vol.297 , pp. 2267-2270
    • Martin-Lluesma, S.1    Stucke, V.M.2    Nigg, E.A.3
  • 32
    • 0028134981 scopus 로고
    • A MAP kinase-dependent spindle assembly checkpoint in Xenopus egg extracts
    • Minshull, J., Sun, H., Tonks, N.K., and Murray, A.W. 1994. A MAP kinase-dependent spindle assembly checkpoint in Xenopus egg extracts. Cell 79: 475-486.
    • (1994) Cell , vol.79 , pp. 475-486
    • Minshull, J.1    Sun, H.2    Tonks, N.K.3    Murray, A.W.4
  • 33
    • 0026266161 scopus 로고
    • Cell cycle extracts
    • Murray, A.W. 1991. Cell cycle extracts. Methods Cell Biol. 36: 581-605.
    • (1991) Methods Cell Biol. , vol.36 , pp. 581-605
    • Murray, A.W.1
  • 34
    • 0034810261 scopus 로고    scopus 로고
    • A conserved protein, Nuf2, is implicated in connecting the centromere to the spindle during chromosome segregation: A link between the kinetochore function and the spindle checkpoint
    • Nabetani, A., Koujin, T., Tsutsumi, C., Haraguchi, T., and Hiraoka, Y. 2001. A conserved protein, Nuf2, is implicated in connecting the centromere to the spindle during chromosome segregation: A link between the kinetochore function and the spindle checkpoint. Chromosoma 110: 322-334.
    • (2001) Chromosoma , vol.110 , pp. 322-334
    • Nabetani, A.1    Koujin, T.2    Tsutsumi, C.3    Haraguchi, T.4    Hiraoka, Y.5
  • 35
    • 0034700087 scopus 로고    scopus 로고
    • A computationally directed screen identifying interacting coiled coils from Saccharomyces cerevisiae
    • Newman, J.R., Wolf, E., and Kim, P.S. 2000. A computationally directed screen identifying interacting coiled coils from Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. 97: 13203-13208.
    • (2000) Proc. Natl. Acad. Sci. , vol.97 , pp. 13203-13208
    • Newman, J.R.1    Wolf, E.2    Kim, P.S.3
  • 36
    • 0028298370 scopus 로고
    • Nuf2, a spindle pole body-associated protein required for nuclear division in yeast
    • Osborne, M.A., Schlenstedt, G., Jinks, T., and Silver, P.A. 1994. Nuf2, a spindle pole body-associated protein required for nuclear division in yeast. J. Cell Biol. 125: 853-866.
    • (1994) J. Cell Biol. , vol.125 , pp. 853-866
    • Osborne, M.A.1    Schlenstedt, G.2    Jinks, T.3    Silver, P.A.4
  • 37
    • 0033636539 scopus 로고    scopus 로고
    • The Bub2p spindle checkpoint links nuclear migration with mitotic exit
    • Pereira, G., Hofken, T., Grindlay, J., Manson, C., and Schiebel, E. 2000. The Bub2p spindle checkpoint links nuclear migration with mitotic exit. Mol. Cell 6: 1-10.
    • (2000) Mol. Cell , vol.6 , pp. 1-10
    • Pereira, G.1    Hofken, T.2    Grindlay, J.3    Manson, C.4    Schiebel, E.5
  • 38
    • 0026650005 scopus 로고
    • CENP-C, an autoantigen in scleroderma, is a component of the human inner kinetochore plate
    • Saitoh, H., Tomkiel, J., Cooke, C.A., Ratrie III, H., Maurer, M., Rothfield, N.F., and Earnshaw, W.C. 1992. CENP-C, an autoantigen in scleroderma, is a component of the human inner kinetochore plate. Cell 70: 115-125.
    • (1992) Cell , vol.70 , pp. 115-125
    • Saitoh, H.1    Tomkiel, J.2    Cooke, C.A.3    Ratrie H. III4    Maurer, M.5    Rothfield, N.F.6    Earnshaw, W.C.7
  • 39
    • 0035897419 scopus 로고    scopus 로고
    • Stu2 promotes mitotic spindle elongation in anaphase
    • Severin, F., Habermann, B., Huffaker, T., and Hyman, T. 2001. Stu2 promotes mitotic spindle elongation in anaphase. J. Cell Biol. 153: 435-442.
    • (2001) J. Cell Biol. , vol.153 , pp. 435-442
    • Severin, F.1    Habermann, B.2    Huffaker, T.3    Hyman, T.4
  • 40
    • 0034704182 scopus 로고    scopus 로고
    • Waiting for anaphase: Mad2 and the spindle assembly checkpoint
    • Shah, J.V. and Cleveland, D.W. 2000. Waiting for anaphase: Mad2 and the spindle assembly checkpoint. Cell 103: 997-1000.
    • (2000) Cell , vol.103 , pp. 997-1000
    • Shah, J.V.1    Cleveland, D.W.2
  • 41
    • 0014007813 scopus 로고
    • Determination of molecular weights and frictional ratios of proteins in impure systems by use of gel filtration and density gradient centrifugation. Application to crude preparations of sulfite and hydroxylamine reductases
    • Siegel, L.M. and Monty, K.J. 1966. Determination of molecular weights and frictional ratios of proteins in impure systems by use of gel filtration and density gradient centrifugation. Application to crude preparations of sulfite and hydroxylamine reductases. Biochim. Biophys. Acta 112: 346-362.
    • (1966) Biochim. Biophys. Acta , vol.112 , pp. 346-362
    • Siegel, L.M.1    Monty, K.J.2
  • 43
    • 0034597552 scopus 로고    scopus 로고
    • The Bfa1/Bub2 GAP complex comprises a universal checkpoint required to prevent mitotic exit
    • Wang, Y., Hu, F., and Elledge, S.J. 2000. The Bfa1/Bub2 GAP complex comprises a universal checkpoint required to prevent mitotic exit. Curr. Biol. 10: 1379-1382.
    • (2000) Curr. Biol. , vol.10 , pp. 1379-1382
    • Wang, Y.1    Hu, F.2    Elledge, S.J.3
  • 44
    • 0035931755 scopus 로고    scopus 로고
    • The Ndc80p complex from Saccharomyces cerevisiae contains conserved centromere components and has a function in chromosome segregation
    • Wigge, P.A. and Kilmartin, J.V. 2001. The Ndc80p complex from Saccharomyces cerevisiae contains conserved centromere components and has a function in chromosome segregation. J. Cell Biol. 152: 349-360.
    • (2001) J. Cell Biol. , vol.152 , pp. 349-360
    • Wigge, P.A.1    Kilmartin, J.V.2
  • 45
    • 0031750102 scopus 로고    scopus 로고
    • Analysis of the Saccharomyces spindle pole by matrix-assisted laser desorption/ionization (MALDI) mass spectrometry
    • Wigge, P.A., Jensen, O.N., Holmes, S., Soues, S., Mann, M., and Kilmartin, J.V. 1998. Analysis of the Saccharomyces spindle pole by matrix-assisted laser desorption/ionization (MALDI) mass spectrometry. J. Cell Biol. 141: 967-977.
    • (1998) J. Cell Biol. , vol.141 , pp. 967-977
    • Wigge, P.A.1    Jensen, O.N.2    Holmes, S.3    Soues, S.4    Mann, M.5    Kilmartin, J.V.6
  • 46
    • 0025779517 scopus 로고
    • MPS1 and MPS2: Novel yeast genes defining distinct steps of spindle pole body duplication
    • Winey, M., Goetsch, L., Baum, P., and Byers, B. 1991. MPS1 and MPS2: Novel yeast genes defining distinct steps of spindle pole body duplication. J. Cell Biol. 114: 745-754.
    • (1991) J. Cell Biol. , vol.114 , pp. 745-754
    • Winey, M.1    Goetsch, L.2    Baum, P.3    Byers, B.4
  • 47
    • 0025866858 scopus 로고
    • Chemical subdomains within the kinetochore domain of isolated CHO mitotic chromosomes
    • Wordeman, L., Steuer, E.R., Sheetz, M.P., and Mitchison, T. 1991. Chemical subdomains within the kinetochore domain of isolated CHO mitotic chromosomes. J. Cell Biol. 114: 285-294.
    • (1991) J. Cell Biol. , vol.114 , pp. 285-294
    • Wordeman, L.1    Steuer, E.R.2    Sheetz, M.P.3    Mitchison, T.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.