Control of microtubule dynamics by the antagonistic activities of XMAP215 and XKCM1 in Xenopus egg extracts

Nature Cell Biology

Volumn 2, Issue 1, 2000, Pages 13-19

  Tournebize, Régis ^a,b   Popov, Andrei ^a   Kinoshita, Kazuhisa ^a   Ashford, Anthony J ^a   Rybina, Sonja ^a   Pozniakovsky, Andrei ^a   Mayer, Thomas U ^a   Walczak, Claire E ^c   Karsenti, Eric ^a   Hyman, Anthony A ^a  

^a EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^b INSTITUT PASTEUR   (France)

^c INDIANA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

KINESIN; MICROTUBULE ASSOCIATED PROTEIN; PROTEIN XKCM 1; PROTEIN XMAP 215; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL GROWTH; CONTROLLED STUDY; ENZYME ACTIVITY; INTERPHASE; MICROTUBULE; MITOSIS; MOLECULAR CLONING; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN STABILITY; SEQUENCE HOMOLOGY; XENOPUS;

ANIMALS; CLONING, MOLECULAR; DNA, COMPLEMENTARY; EVOLUTION, MOLECULAR; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; KINESIN; MICROTUBULE-ASSOCIATED PROTEINS; MICROTUBULES; MITOSIS; MITOTIC SPINDLE APPARATUS; MOLECULAR SEQUENCE DATA; OOCYTES; PHYLOGENY; RABBITS; SEQUENCE HOMOLOGY, AMINO ACID; XENOPUS; XENOPUS PROTEINS;

AMPHIBIA; ANIMALIA; REPTILIA;

EID: 0033792092     PISSN: 14657392     EISSN: None     Source Type: Journal    
DOI: 10.1038/71330     Document Type: Article

References (43)

1. Dynamic instability of microtubule growth
2. Microtubule polymerization dynamics
3. Dynamic instability of individual microtubules analyzed by video light microscopy: Rate constants and transition frequencies
4. Accessory protein regulation of microtubule dynamics throughout the cell cycle
5. XMAP from Xenopus eggs promotes rapid plus end assembly of microtubules and rapid microtubule polymer turnover
6. Phosphorylation by CDK1 regulates XMAP215 function in vitro
7. Effect on microtubule dynamics of XMAP230, a microtubule-associated protein present in Xenopus laevis eggs and dividing cells
8. XMAP310: A Xenopus rescue-promoting factor localized to the mitotic spindle
9. Identification of a protein that interacts with tubulin dimers and increases the catastrophe rate of microtubules
10. XKCM1: A Xenopus kinesin-related protein that regulates microtubule dynamics during mitotic spindle assembly
11. The stathmin/tubulin interaction in vitro
12. Kin 1 kinesins are microtubule-destabilizing enzymes
13. Dissociation of the tubulin-sequestering and microtubule catastrophe-promoting activities of oncoprotein 18/stathmin
14. A microtubule-associated protein from Xenopus eggs that specifically promotes assembly at the plus-end
15. The TOGp protein is a new human microtubule-associated protein homologous to the Xenopus XMAP215
16. Mini spindles: A gene encoding a conserved microtubule-associated protein required for the integrity of the mitotic spindle in Drosophila
17. ZYG-9, a Caenorhabditis elegans protein required for microtubule organization and function, is a component of mitotic and mitotic spindle poles
18. Stu2p: A microtubule-binding protein that is an essential component of the yeast spindle pole body
19. p93dis1, which is required for sister chromatid separation, is a novel microtubule and spindle pole body-associating protein phosphorylated at the Cdc2 target sites
20. Dissection of fission yeast microtubule associating protein p93Dis1: Regions implicated in regulated localization and microtubule interaction
21. Cold-sensitive and caffeine-supersensitive mutants of the Schizosaccharomyces pombe dis genes implicated in sister chromatid separation during mitosis
22. Characterization of the cDNA and pattern of expression of a new gene overexpressed in human hepatomas and colonic tumors
23. Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081 -KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1
24. HEAT repeats in the Huntington's disease protein
25. MARK, a novel family of protein kinases that phosphorylate microtubule-associated proteins and trigger microtubule disruption
26. Molecular cloning of a ubiquitously distributed microtubule-associated protein with Mr 190,000
27. Non-neuronal 210 x 10(3) Mr microtubule-associated protein (MAP4) contains a domain homologous to the microtubule-binding domains of neuronal MAP2 and tau
28. Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: Identification as the microtubule-associated protein tau
29. A model for microtubule-associated protein 4 structure. Domains defined by comparisons of human, mouse, and bovine sequences
30. Distinct roles of PP1 and PP2A-like phosphatases in control of microtubule dynamics during mitosis
31. Stimulation of microtubule aster formation and spindle assembly by the small GTPase Ran
32. Regulation of a major microtubule-associated protein by MPF and MAP kinase
33. Dynamic localization of CLIP-170 to microtubule plus ends is coupled to microtubule assembly
34. CLIP-170 highlights growing microtubule ends in vivo
35. Colocalization of cytoplasmic dynein with dynactin and CLIP-170 at microtubule distal ends
36. Kinetochores distinguish GTP from GDP forms of the microtubule lattice
37. Mitotic chromatin regulates phosphorylation of Stathmin/Op18
38. Control of microtubule dynamics and length by cyclin A- and cyclin B-dependent kinases in Xenopus egg extracts
39. Rapid production of full-length cDNAs from rare transcripts: Amplification using a single gene-specific oligonucleotide primer
40. Mitotic spindle assembly by two different pathways in vitro
41. Purification of cytoskeletal proteins using peptide antibodies