Evaluation of the genotoxicity of piplartine, an alkamide of Piper tuberculatum, in yeast and mammalian V79 cells

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 652, Issue 2, 2008, Pages 164-174

  Bezerra, Daniel Pereira ^a   Moura, Dinara Jaqueline ^b   Rosa, Renato Moreira ^b   de Vasconcellos, Marne Carvalho ^a   e Silva, Ana Catarina Romano ^b   de Moraes, Manoel Odorico ^a   Silveira, Edilberto Rocha ^a   Lima, Mary Anne Sousa ^a   Henriques, João Antonio Pegas ^b,c   Costa Lotufo, Letícia Veras ^a   Saffi, Jenifer ^b,c  

^a FEDERAL UNIVERSITY OF CEARÁ   (Brazil)

^b FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^c UNIVERSIDADE LUTERANA DO BRASIL   (Brazil)

Author keywords

Apoptosis; Genotoxicity; Mutagenesis; Piplartine; Recombinogenesis

Indexed keywords

CELL DNA; HERBACEOUS AGENT; PIPLARTINE;

ANIMAL CELL; APOPTOSIS; ARTICLE; BIOACCUMULATION; BIOLOGICAL ACTIVITY; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL GROWTH; CELL STRAIN V 79; COMET ASSAY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA DAMAGE; DNA FRAGMENTATION; DNA STRAND BREAKAGE; DRUG POTENCY; FRAMESHIFT MUTATION; GENOTOXICITY; MAMMAL CELL; MEDICINAL PLANT; MITOCHONDRIAL MEMBRANE POTENTIAL; MUTAGENICITY; MUTATION RATE; NONHUMAN; NUCLEOSOME; PIPER TUBERCULATUM; PIPERACEAE; POINT MUTATION; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; TUMOR CELL LINE; YEAST CELL;

ANIMALS; APOPTOSIS; CELL CYCLE; CELL LINE; COMET ASSAY; CRICETINAE; CRICETULUS; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; MEMBRANE POTENTIAL, MITOCHONDRIAL; MUTAGENICITY TESTS; PIPER; PIPERIDONES; SACCHAROMYCES CEREVISIAE;

MAMMALIA; PIPER TUBERCULATUM; PIPERACEAE; SACCHAROMYCES CEREVISIAE;

EID: 42749089537     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2008.02.001     Document Type: Article

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