In vitro genotoxicity of the West African anti-malarial herbal Cryptolepis sanguinolenta and its major alkaloid cryptolepine

Toxicology

Volumn 208, Issue 1, 2005, Pages 141-147

  Ansah, Charles ^a   Khan, Ayesha ^a   Gooderham, Nigel J ^a  

^a Faculty of Medicine   (United Kingdom)

Author keywords

Cryptolepine; Cryptolepis sanguinolenta; Hprt mutation; Micronuclei

Indexed keywords

ALKALOID; ANTIMALARIAL AGENT; CRYPTOLEPINE; CRYPTOLEPIS SANGUINOLENTA EXTRACT; PLANT EXTRACT; UNCLASSIFIED DRUG;

ANIMAL CELL; AQUEOUS SOLUTION; ARTICLE; CELL SURVIVAL; CHINESE HAMSTER; CONCENTRATION RESPONSE; CONTROLLED STUDY; CRYPTOLEPIS SANGUINOLENTA; DNA DAMAGE; DRUG FORMULARY; FIBROBLAST; GENE FREQUENCY; GENE INDUCTION; GENETIC DISORDER; GENOTOXICITY; INTERMETHOD COMPARISON; MEDICINAL PLANT; MICRONUCLEUS; MUTAGENESIS; NONHUMAN; PLANT ROOT; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE;

AFRICA; ALKALOIDS; ANIMALS; ANTIMALARIALS; CELL LINE; CELL SURVIVAL; CRICETINAE; CRYPTOLEPIS; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; INDOLES; INTERCALATING AGENTS; MEDICINE, TRADITIONAL; MUTAGENICITY TESTS; PLANT EXTRACTS; PLANT ROOTS; QUINOLINES;

CRICETINAE; CRICETULUS GRISEUS; CRYPTOLEPIS; MAMMALIA; PERIPLOCOIDEAE;

EID: 12444305985     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2004.11.026     Document Type: Article

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