메뉴 건너뛰기




Volumn 627, Issue 1, 2007, Pages 31-35

Fourth International Workgroup on Genotoxicity testing: Results of the in vivo Comet assay workgroup

(15)  Burlinson, Brian a   Tice, Raymond R b   Speit, Günter c   Agurell, Eva d   Brendler Schwaab, Susanne Y e   Collins, Andrew R f   Escobar, Patricia g   Honma, Masamitsu h   Kumaravel, Tirukalikundram S i   Nakajima, Madoka j   Sasaki, Yu F k   Thybaud, Veronique l   Uno, Yoshifumi m   Vasquez, Marie n   Hartmann, Andreas o  


Author keywords

Alkaline electrophoresis; Comet assay; DNA damage; Genotoxicity; Single cell gel assay

Indexed keywords

ALKALINITY; APOPTOSIS; ARTICLE; CELL ISOLATION; CLINICAL PROTOCOL; COMET ASSAY; CONCENTRATION (PARAMETERS); CYTOTOXICITY; EXPERT SYSTEM; GENOTOXICITY; HISTOPATHOLOGY; IMAGE ANALYSIS; IN VIVO STUDY; MEDICAL LITERATURE; PRIORITY JOURNAL; RODENT; SCORING SYSTEM; STANDARDIZATION; TISSUE NECROSIS; UNITED STATES;

EID: 33846262844     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2006.08.011     Document Type: Article
Times cited : (458)

References (31)
  • 1
    • 0021193203 scopus 로고
    • Microelectrophoretic study of radiation induced DNA damages in individual mammalian cells
    • Ostling O., and Johanson K.J. Microelectrophoretic study of radiation induced DNA damages in individual mammalian cells. Biochem. Biophys. Res. Commun. 123 (1984) 291-298
    • (1984) Biochem. Biophys. Res. Commun. , vol.123 , pp. 291-298
    • Ostling, O.1    Johanson, K.J.2
  • 2
    • 0023919963 scopus 로고
    • A simple technique for quantitation of low levels of DNA damage in individual cells
    • Singh N.P., McCoy M.T., Tice R.R., and Schneider E.L. A simple technique for quantitation of low levels of DNA damage in individual cells. Exp. Cell Res. 175 (1988) 184-191
    • (1988) Exp. Cell Res. , vol.175 , pp. 184-191
    • Singh, N.P.1    McCoy, M.T.2    Tice, R.R.3    Schneider, E.L.4
  • 3
    • 0026005914 scopus 로고
    • The single cell gel (SCG) assay: an electrophoretic technique for the detection of DNA damage in individual cells
    • Witmer C.R., Snyder R.R., Jollow D.J., Kalf G.F., Kocsis J.J., and Sipes I.G. (Eds), Plenum Press, New York
    • Tice R.R., Andrews P.W., Hirai O., and Singh N.P. The single cell gel (SCG) assay: an electrophoretic technique for the detection of DNA damage in individual cells. In: Witmer C.R., Snyder R.R., Jollow D.J., Kalf G.F., Kocsis J.J., and Sipes I.G. (Eds). Biological Reactive Intermediates. IV. Molecular and Cellular Effects and Their Impact on Human Health (1991), Plenum Press, New York 157-164
    • (1991) Biological Reactive Intermediates. IV. Molecular and Cellular Effects and Their Impact on Human Health , pp. 157-164
    • Tice, R.R.1    Andrews, P.W.2    Hirai, O.3    Singh, N.P.4
  • 7
    • 33744770267 scopus 로고    scopus 로고
    • The comet assay-a sensitive genotoxicity test for the detection of DNA damage and repair
    • Henderson D.S. (Ed), Humana Press Inc., Totowa, NJ
    • Speit G., and Hartmann A. The comet assay-a sensitive genotoxicity test for the detection of DNA damage and repair. In: Henderson D.S. (Ed). Methods in Molecular Biology, vol. 113, DNA Repair Protocols: Eucaryotic Systems. 2nd ed. (2006), Humana Press Inc., Totowa, NJ 275-286
    • (2006) Methods in Molecular Biology, vol. 113, DNA Repair Protocols: Eucaryotic Systems. 2nd ed. , pp. 275-286
    • Speit, G.1    Hartmann, A.2
  • 8
    • 24044551627 scopus 로고    scopus 로고
    • The in vivo comet assay: use and status in genotoxicity testing
    • Brendler-Schwaab S.Y., Hartmann A., Pfuhler S., and Speit G. The in vivo comet assay: use and status in genotoxicity testing. Mutagenesis 20 (2005) 245-254
    • (2005) Mutagenesis , vol.20 , pp. 245-254
    • Brendler-Schwaab, S.Y.1    Hartmann, A.2    Pfuhler, S.3    Speit, G.4
  • 9
    • 0033670360 scopus 로고    scopus 로고
    • The comet assay with multiple mouse organs: comparison of comet assay results and carcinogenicity with 208 chemicals selected from the IARC monographs and US NTP Carcinogenicity Database
    • Sasaki Y.F., Sekihashi K., Izumiyama F., Nishidate E., Saga A., Ishida K., and Tsuda S. The comet assay with multiple mouse organs: comparison of comet assay results and carcinogenicity with 208 chemicals selected from the IARC monographs and US NTP Carcinogenicity Database. Crit. Rev. Toxicol. 30 (2000) 629-799
    • (2000) Crit. Rev. Toxicol. , vol.30 , pp. 629-799
    • Sasaki, Y.F.1    Sekihashi, K.2    Izumiyama, F.3    Nishidate, E.4    Saga, A.5    Ishida, K.6    Tsuda, S.7
  • 12
    • 0003500730 scopus 로고    scopus 로고
    • COM (United Kingdom Committee on Mutagenicity of Chemicals in Food, Consumer Products, and the Environment), COM
    • COM (United Kingdom Committee on Mutagenicity of Chemicals in Food, Consumer Products, and the Environment). Guidance on a Strategy for Testing of Chemicals for Mutagenicity (2000), COM
    • (2000) Guidance on a Strategy for Testing of Chemicals for Mutagenicity
  • 14
    • 84874562357 scopus 로고    scopus 로고
    • Mammalian erythrocyte micronucleus test
    • OECD, OECD, Paris (test guideline)
    • OECD. Mammalian erythrocyte micronucleus test. OECD Guidelines for the Testing of Chemicals vol. 474 (1997), OECD, Paris (test guideline)
    • (1997) OECD Guidelines for the Testing of Chemicals , vol.474
  • 15
    • 33846194367 scopus 로고    scopus 로고
    • M. Hayashi, J.T. MacGregor, D.G. Gatehouse, D.H. Blakey, S.D. Dertinger, L. Abramsson-Zetterberg, G. Krishna, T. Morita, A. Russo, N. Asano, H. Suzuki, W. Ohyama, D. Gibson, In vivo erythrocyte micronucleus assay. III. Validation and regulatory acceptance of automated scoring and the use of rat peripheral blood reticulocytes, with discussion of non-hematopoietic target cells and a single dose-level limit test, Mutat. Res., this issue.
  • 16
    • 0031565913 scopus 로고    scopus 로고
    • In vivo genotoxicity of ortho-phenylphenol, biphenyl, and thiabendazole detected in multiple mouse organs by the alkaline single cell gel electrophoresis assay
    • Sasaki Y.F., Saga A., Akasaka M., Yoshida K., Nishidate E., Su Y.Q., Matsusaka N., and Tsuda S. In vivo genotoxicity of ortho-phenylphenol, biphenyl, and thiabendazole detected in multiple mouse organs by the alkaline single cell gel electrophoresis assay. Mutat. Res. 395 (1997) 189-198
    • (1997) Mutat. Res. , vol.395 , pp. 189-198
    • Sasaki, Y.F.1    Saga, A.2    Akasaka, M.3    Yoshida, K.4    Nishidate, E.5    Su, Y.Q.6    Matsusaka, N.7    Tsuda, S.8
  • 18
    • 0028884765 scopus 로고
    • Sizing highly fragmented DNA in individual apoptotic cells using the comet assay and a DNA crosslinking agent
    • Olive P.L., and Banath J.P. Sizing highly fragmented DNA in individual apoptotic cells using the comet assay and a DNA crosslinking agent. Exp. Cell. Res. 221 (1995) 19-26
    • (1995) Exp. Cell. Res. , vol.221 , pp. 19-26
    • Olive, P.L.1    Banath, J.P.2
  • 19
    • 0031973021 scopus 로고    scopus 로고
    • The ability of the comet assay to discriminate between gentoxins and cytotoxins
    • Henderson L., Wolfreys A., Fedyk J., Bourner C., and Windebank S. The ability of the comet assay to discriminate between gentoxins and cytotoxins. Mutagenesis 13 (1998) 89-94
    • (1998) Mutagenesis , vol.13 , pp. 89-94
    • Henderson, L.1    Wolfreys, A.2    Fedyk, J.3    Bourner, C.4    Windebank, S.5
  • 20
    • 0035909496 scopus 로고    scopus 로고
    • Influence of cytotoxicity and compound precipitation on test results in the alkaline comet assay
    • Hartmann A., Kiskinis E., Fjaellman A., and Suter W. Influence of cytotoxicity and compound precipitation on test results in the alkaline comet assay. Mutat. Res. 497 (2001) 199-212
    • (2001) Mutat. Res. , vol.497 , pp. 199-212
    • Hartmann, A.1    Kiskinis, E.2    Fjaellman, A.3    Suter, W.4
  • 21
    • 0037684896 scopus 로고    scopus 로고
    • Characterization of cytotoxic and genotoxic effects of different compounds in CHO K5 cells with the comet assay (single-cell gel electrophoresis assay)
    • Kiffe M., Christen P., and Arni P. Characterization of cytotoxic and genotoxic effects of different compounds in CHO K5 cells with the comet assay (single-cell gel electrophoresis assay). Mutat. Res. 537 (2003) 151-168
    • (2003) Mutat. Res. , vol.537 , pp. 151-168
    • Kiffe, M.1    Christen, P.2    Arni, P.3
  • 22
    • 0041733963 scopus 로고    scopus 로고
    • The comet assay: genotoxic damage or nuclear fragmentation?
    • Rundell M.S., Wagner E.D., and Plewa M.J. The comet assay: genotoxic damage or nuclear fragmentation?. Environ. Molec. Mutagen. 42 (2003) 61-67
    • (2003) Environ. Molec. Mutagen. , vol.42 , pp. 61-67
    • Rundell, M.S.1    Wagner, E.D.2    Plewa, M.J.3
  • 25
    • 0032501069 scopus 로고    scopus 로고
    • Detection of in vivo genotoxicity of haloalkanes and haloalkenes carcinogenic to rodents by the alkaline single cell gel electrophoresis (Comet) assay in multiple mouse organs
    • Sasaki Y.F., Saga A., Akasaka M., Ishibashi S., Yoshida K., Su Y.Q., Matsusaka N., and Tsuda S. Detection of in vivo genotoxicity of haloalkanes and haloalkenes carcinogenic to rodents by the alkaline single cell gel electrophoresis (Comet) assay in multiple mouse organs. Mutat. Res. 419 (1998) 13-20
    • (1998) Mutat. Res. , vol.419 , pp. 13-20
    • Sasaki, Y.F.1    Saga, A.2    Akasaka, M.3    Ishibashi, S.4    Yoshida, K.5    Su, Y.Q.6    Matsusaka, N.7    Tsuda, S.8
  • 26
    • 0025962780 scopus 로고
    • Non-random cell killing in cryopreservation: implications for performance of the battery of leukocyte tests (BLT). I. Toxic and immunotoxic effects
    • Strauss G.H.S. Non-random cell killing in cryopreservation: implications for performance of the battery of leukocyte tests (BLT). I. Toxic and immunotoxic effects. Mutat. Res. 252 (1991) 1-15
    • (1991) Mutat. Res. , vol.252 , pp. 1-15
    • Strauss, G.H.S.1
  • 27
    • 0002860482 scopus 로고    scopus 로고
    • Detecting genotoxic activity against high molecular weight DNA using the alkaline single cell gel (SCG) assay
    • Vasquez M., and Tice R.R. Detecting genotoxic activity against high molecular weight DNA using the alkaline single cell gel (SCG) assay. Environ. Molec. Mutagen. 29 (1997) 53
    • (1997) Environ. Molec. Mutagen. , vol.29 , pp. 53
    • Vasquez, M.1    Tice, R.R.2
  • 28
    • 0028833163 scopus 로고
    • The kinetics of repair of oxidative DNA damage (strand breaks and oxidised pyrimidines) in human cells
    • Collins A.R., Ai-guo A., and Duthie S.J. The kinetics of repair of oxidative DNA damage (strand breaks and oxidised pyrimidines) in human cells. Mutat. Res. 336 (1995) 69-77
    • (1995) Mutat. Res. , vol.336 , pp. 69-77
    • Collins, A.R.1    Ai-guo, A.2    Duthie, S.J.3
  • 29
    • 0025270234 scopus 로고
    • Heterogeneity in radiation-induced DNA damage and repair in tumor and normal cells measured using the "Comet" assay
    • Olive P.L., Banath J.P., and Durand R.E. Heterogeneity in radiation-induced DNA damage and repair in tumor and normal cells measured using the "Comet" assay. Radiat. Res. 122 (1990) 86-94
    • (1990) Radiat. Res. , vol.122 , pp. 86-94
    • Olive, P.L.1    Banath, J.P.2    Durand, R.E.3
  • 30
    • 33646793694 scopus 로고    scopus 로고
    • Reliable Comet assay measurements for detecting DNA damage induced by ionising radiation and chemicals
    • Kumaravel T.S., and Jha A.N. Reliable Comet assay measurements for detecting DNA damage induced by ionising radiation and chemicals. Mutat. Res. 605 (2006) 7-16
    • (2006) Mutat. Res. , vol.605 , pp. 7-16
    • Kumaravel, T.S.1    Jha, A.N.2
  • 31
    • 0037339240 scopus 로고    scopus 로고
    • Aspects of design and statistical analysis in the comet assay
    • Wiklund S.J., and Agurell E. Aspects of design and statistical analysis in the comet assay. Mutagenesis 18 (2003) 167-175
    • (2003) Mutagenesis , vol.18 , pp. 167-175
    • Wiklund, S.J.1    Agurell, E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.