Impaired learning-dependent cortical plasticity in Huntington's disease transgenic mice

Neurobiology of Disease

Volumn 17, Issue 3, 2004, Pages 427-434

  Cybulska Klosowicz, Anita ^a   Mazarakis, Nektarios K ^b   Van Dellen, Anton ^b   Blakemore, Colin ^b   Hannan, Anthony J ^b,c   Kossut, Malgorzata ^a  

^a NENCKI INSTITUTE OF EXPERIMENTAL BIOLOGY   (Poland)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

2 deoxyglucose autoradiography; Associative learning; Barrel cortex; Huntington's disease; Plasticity

Indexed keywords

DEOXYGLUCOSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN MAPPING; CELL DEATH; CONTROLLED STUDY; HUNTINGTON CHOREA; LEARNING DISORDER; MOUSE; NERVE CELL PLASTICITY; NEUROPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; STATE DEPENDENT LEARNING; TRANSGENIC MOUSE;

ANIMALS; AUTORADIOGRAPHY; BIOLOGICAL TRANSPORT; CARBON RADIOISOTOPES; CONDITIONING, CLASSICAL; CROSSES, GENETIC; DEOXYGLUCOSE; DISEASE MODELS, ANIMAL; HUMANS; HUNTINGTON DISEASE; LEARNING; MICE; MICE, INBRED DBA; MICE, TRANSGENIC; MOTOR ACTIVITY; NERVE TISSUE PROTEINS; NEURONAL PLASTICITY; NUCLEAR PROTEINS; TOUCH; VIBRISSAE;

EID: 9644279554     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2004.08.009     Document Type: Article

References (52)

1. M.F. Bear NMDA-receptor-dependent synaptic plasticity in the visual cortex Prog. Brain Res. 108 1996 205 218
2. P. Calabresi, P. Gubellini, B. Picconi, D. Centoze, A. Pisani, P. Bonsi, P. Greengard, R.A. Hipskind, E. Borrelli, and G. Bernardi Inhibition of mitochondrial complex II induces a long-term potentiation of NMDA-mediated synaptic excitation in the striatum requiring endogenous dopamine J. Neurosci. 21 2001 5110 5120
3. R.J. Carter, L.A. Lione, T. Humby, L. Mangiarini, A. Mahal, G.P. Bates, S.B. Dunnett, and A.J. Morton Characterization of progressive motor deficits in mice transgenic for the human Huntington's disease mutation J. Neurosci. 19 1999 3248 3257
4. C. Cepeda, M.A. Ariano, Ch.R. Calvert, J. Flores-Hernandez, S.H. Chandler, B.R. Leavitt, M.R. Hayden, and M.S. Levine NMDA receptor function in mouse models of Huntington disease J. Neurosci. Res. 66 2001 525 539
5. J.H. Cha, C.M. Kosinski, J.A. Kerner, S.A. Alsdorf, L. Mangiarini, S.W. Davies, J.B. Penney, G.P. Bates, and A.B. Young Altered brain neurotransmitter receptors in transgenic mice expressing a portion of an abnormal human Huntington disease gene Proc. Natl. Acad. Sci. USA 95 1998 6480 6485
6. N. Chen, T. Luo, Ch. Wellington, M. Metzler, K. McCutcheon, M.R. Hayden, and L.A. Raymond Subtype-specific enhancement of NMDA receptor currents by mutant huntingtin J. Neurochem. 72 1999 1890 1898
7. J. Chmielowska, M. Kossut, and M. Chmielowski Single vibrissal cortical column in the mouse labeled with 2-deoxyglucose Exp. Brain Res. 63 1986 607 619
8. S.W. Davies, M. Turmaine, B.A. Cozens, M. DiFiglia, A.H. Sharp, C.A. Ross, E. Scherzinger, E.E. Wanker, L. Mangiarini, and G.P. Bates Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation Cell 90 1997 537 548
9. S.M. De La Monte, J.-P. Vonsattel, and E.P. Richardson Morphometric demonstration of atrophic changes in the cerebral cortex, white matter, and neostriatum in Huntington's disease J. Neuropathol. Exp. Neurol. 47 1988 516 525
10. R. Diamond, R.F. White, R.H. Myers, C. Mastromauro, W.J. Koroshetz, N. Butters, D.M. Rothstein, M.B. Moss, and J. Vasterling Evidence of presymptomatic cognitive decline in Huntington's disease J. Clinic Exp. Neuropsychol. 14 1992 961 975
11. M. DiFiglia, E. Sapp, K.O. Chase, S.W. Davies, G.P. Bates, J.P. Vonsattel, and N. Aronin Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain Science 277 1997 1990 1993
12. T. Foroud, E. Siemers, D. Kleindorfer, D.J. Bill, M.E. Hode, and J.A. Norton Cognitive scores in carriers of Huntington's disease gene compared to noncarriers Ann. Neurol. 37 1995 657 664
13. S. Glazewski, M. McKenna, M. Jacquin, and K. Fox Experience-dependent depression of vibrissae responses in adolescent rat barrel cortex Eur. J. Neurosci. 10 1998 2107 2116
14. P.J. Hand The 2-deoxyglucose method L. Heimer M.J. Robards Neuroanatomical Tracing Methods 1981 Plenum Press New York 511 538
15. O. Hansson, A. Petersen, M. Leist, P. Nicotera, R.F. Castilho, and P. Brundin Transgenic mice expressing a Huntington's disease mutation are resistant to quinolinic acid-induced striatal excitotoxicity Proc. Natl. Acad. Sci. U. S. A. 96 1999 8727 8732
16. O. Hansson, E. Guatteo, N.B. Mercuri, G. Bernardi, X.-J. Li, R.F. Castilho, and P. Brundin Resistance to NMDA toxicity correlates with appearance of nuclear inclusions, behavioural deficits and changes in calcium homeostasis in mice transgenic for exon 1 of the Huntington gene Eur. J. Neurosci. 14 2001 1492 1504
17. L.W. Ho, J. Carmichael, J. Swartz, A. Wyttenbach, J. Rankin, and D.C. Rubinsztein The molecular biology of Huntington's disease Psychiatry Med. 31 2001 3 14
18. Huntington's Disease Collaborative Research Group A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes Cell 72 1993 971 983
19. B. Jablonska, M. Gierdalski, E. Siucinska, J. Skangiel-Kramska, and M. Kossut Partial blocking of NMDA receptors restricts plastic changes in adult mouse barrel cortex Behav. Brain Res. 66 1995 207 216
20. G.J. Klapstein, R.S. Fisher, H. Znajani, C. Cepeda, E.S. Jokel, M.-F. Chesselet, and M.S. Levine Electrophysiological and morphological changes in striatal spiny neurons in R6/2 Huntington's disease transgenic mice J. Neurophysiol. 86 2001 2667 2677
21. M. Kossut Plasticity of the barrel cortex neurons Prog. Neurobiol. 39 1992 389 422
22. M. Kossut Imaging functional representations in the barrel cortex-Effects of denervation, deprivation and learning M. Kossut Plasticity of Adult Barrel Cortex 2000 Graham Publishing New York 175 201
23. M. Kossut, and S.C. Juliano Anatomical correlates of representational map reorganization induced by partial vibrissectomy in the barrel cortex of adult mice Neuroscience 92 1999 807 817
24. G.A. Laforet, E. Sapp, K. Chase, Ch. McIntyre, F.M. Boyce, M. Campbell, B.A. Cadigan, L. Warzecki, D.A. Tagle, P.H. Reddy, C. Cepeda, Ch.R. Calvert, E.S. Jokel, G.J. Klapstein, M.A. Ariano, M.S. Levine, M. DiFiglia, and N. Aronin Changes in cortical and striatal neurons predict behavioral and electrophysiological abnormalities in a transgenic murine model of Huntington's disease J. Neurosci. 21 2001 9112 9123
25. A.D. Lawrence, B.J. Sahakian, J.R. Hodges, A.E. Rosser, K.W. Lange, and T.W. Robbins Executive and mnemonic functions in early Huntington's disease Brain 119 1996 1633 1645
26. A.D. Lawrence, J.R. Hodges, A.E. Rosser, A. Kershaw, C. ffrench-Constant, D.C. Rubinsztein, T.W. Robbins, and B.J. Sahakian Evidence for specific cognitive deficits in preclinical Huntington's disease Brain 121 1998 1329 1341
27. M.S. Levine, G.J. Klapstein, A. Kopple, E. Gruen, C. Cepeda, M.E. Vargas, E.S. Jokel, E.M. Carpenter, H. Zanjani, R.S. Hurst, A. Efstratiadis, S. Zeitlin, and M.-F. Chesselet Enhanced sensitivity to N-methyl-d-aspartate receptor activation in transgenic and knockin mouse models of Huntington's disease J. Neurosci. Res. 58 1999 515 532
28. J.C. Lievens, B. Woodman, A. Mahal, O. Spasic-Boscovic, D. Samuel, L. Kerkerian-Le Goff, and G.P. Bates Impaired glutamate uptake in the R6 Huntington's disease transgenic mice Neurobiol. Dis. 8 2001 807 821
29. J.-Ch. Lievens, B. Woodman, A. Mahal, and G.P. Bates Abnormal phosphorylation of synapsin I predicts a neuronal transmission impairment in the R6/2 Huntington's disease transgenic mice Mol. Cell. Neurosci. 20 2002 638 648
30. L.A. Lione, R.J. Carter, M.J. Hunt, G.P. Bates, A.J. Morton, and S.B. Dunnett Selective discrimination learning impairments in mice expressing the human Huntington's disease mutation J. Neurosci. 19 1999 10428 10437
31. L. Mangiarini, K. Sathasivam, M. Seller, B. Cozens, A. Harper, C. Hetherington, M. Lawton, Y. Trottier, H. Lenrach, S.W. Davies, and G.P. Bates Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice Cell 87 1996 493 506
32. N.K. Mazarakis, A. Cybulska-Klosowicz, A.J. Hannan, M. Kossut, and C. Blakemore Learning-induced plasticity in the mouse barrel cortex assessed with intrinsic signal optical imaging Abstr.-Soc. Neurosci. 27 2001 393.8
33. Mazarakis, N.K., Cybulska-Klosowicz, A., Grote, H., Van Dellen, A., Kossut, M., Blakemore, C., Hannan, A.J., submitted for publication. Experience-dependent cortical plasticity and sensory discrimination learning deficits in presymptomatic Huntington's disease mice.
34. K.P.S.J. Murphy, R.J. Carter, L.A. Lione, L. Mangiarini, A. Mahal, G.P. Bates, S.B. Dunnett, and A.J. Morton Abnormal synaptic plasticity and impaired spatial cognition in mice transgenic for exon 1 of the human Huntington's disease mutation J. Neurosci. 20 2000 5115 5123
35. R.H. Myers, J.-P. Vonsattel, T.J. Stevens, L.A. Cupples, E.P. Richerdson, J.B. Martin, and E.D. Bird Clinical and neuropathologic assessment of severity in Huntington's disease Neurology 38 1988 341 347
36. B. Naver, C. Stub, M. Moller, K. Fenger, A.K. Hansen, L. Hasholt, and S.A. Sorensen Molecular and behavioural analysis of the R6/1 Huntington's disease transgenic mouse Neuroscience 122 2003 1049 1057
37. V. Rema, M. Armstrong-James, and F.F. Ebner Experience-dependent plasticity of adult rat SI cortex requires local NMDA receptor activation J. Neurosci. 18 1998 10196 10206
38. D.C. Rubinsztein Lessons from animal models of Huntington's disease Trends Genet. 18 2002 202 210
39. E. Sapp, J. Penney, A. Young, N. Aronin, J.P. Vonsattel, and M. DiFiglia Axonal transport of N-terminal huntingtin suggests early pathology of corticostriatal projections in Huntington disease J. Neuropathol. Exp. Neurol. 58 1999 165 173
40. E. Siucinska, and M. Kossut Short-lasting classical conditioning induces reversible changes of representational maps of vibrissae in mouse SI cortex-A 2DG study Cereb. Cortex 6 1996 506 513
41. L. Sokoloff, M. Reivich, C. Kennedy, M.H. De Rosiers, C.S. Patlak, K.D. Pettigrew, O. Sakurada, and M. Shinohara The [14C]deoxyglucose method for the measurement of local cerebral glucose utilization: theory, procedure, and normal values in the conscious and anesthetized albino rat J. Neurochem. 28 1977 897 916
42. T.L. Spires, H.E. Grote, S. Garry, P.M. Cordery, A. Van Dellen, C. Blakemore, and A.J. Hannan Dendritic spine pathology and deficits in experience-dependent dendritic plasticity in R6/1 Huntington's disease transgenic mice Eur. J. Neurosci. 19 2004 2799 2807
43. K. Tang, M.J. Low, D.K. Grandy, and D.M. Lovinger Dopamine-dependent synaptic plasticity in striatum during development Proc. Natl. Acad. Sci. U. S. A. 98 2001 1255 1260
44. A. Van Dellen, C. Blakemore, R. Deacon, D. York, and A.J. Hannan Delaying the onset of Huntington's in mice Nature 404 2000 721 722
45. A. Van Dellen, R. Deacon, D. York, C. Blakemore, and A.J. Hannan Anterior cingulated cortical transplantation in transgenic Huntington's disease mice Brain Res. Bull. 56 2001 313 318
46. J. Vonsattel, and M. DiFiglia Huntington's disease J. Neuropathol. Exp. Neurol. 57 1998 369 384
47. J.-P. Vonsattel, H. Richard, R.H. Myers, T.J. Stevens, R.J. Ferrante, E.D. Bird, and E.P. Richardson Neuropathological classification of Huntington's disease J. Neuropathol. Exp. Neurol. 44 1985 559 577
48. E. Welker, S.B. Rao, J. Dorfl, P. Melzer, and H. van der Loos Plasticity in the barrel cortex of the adult mouse: effects of chronic stimulation upon deoxyglucose uptake in the behaving animal J. Neurosci. 12 1992 153 170
49. Ch.L. Wellington, L.M. Ellerby, C.-A. Gutekunst, D. Rogers, S. Warby, R.K. Graham, O. Loubser, J. van Raamsdonk, R. Singaraja, Y.-Z. Yang, J. Gafni, D. Bredesen, S.M. Hersch, B.R. Leavitt, S. Roy, D.W. Nicholson, and M.R. Hayden Caspase cleavage of mutant huntingtin precede neurodegeneration in Huntington's disease J. Neurosci. 22 2002 7862 7872
50. T.A. Woolsey, and H. Van der Loos The structural organization of layer IV in the somatosensory region (SI) of mouse cerebral cortex. The description of a cortical field composed of discrete cytoarchitectonic units Brain Res. 17 1970 205 242
51. M.M. Zeron, N. Chen, A. Moshaver, A. Ting-Chun Lee, Ch.L. Wellington, M.R. Hayde, and L.A. Raymond Mutant huntingtin enhances excitotoxic cell death Mol. Cell. Neurosci. 17 2001 41 53
52. M.M. Zeron, O. Hansson, N. Chen, Ch.L. Wellington, B.R. Leavitt, P. Brundin, M.R. Hayden, and L.A. Raymond Increased sensitivity to N-methyl-d-aspartate receptor-mediated excitotoxicity in a mouse model of Huntington's disease Neuron 33 2002 849 860