Differential clinical and motor control function in a pair of monozygotic twins with Huntington's disease

Movement Disorders

Volumn 14, Issue 2, 1999, Pages 320-325

  Georgiou, Nellie ^a   Bradshaw, John L ^a   Chiu, Edmond ^b   Tudor, Anne ^c   O'Gorman, Louise ^d   Phillips, Jim G ^a  

^a MONASH UNIVERSITY   (Australia)

^b ST GEORGE HOSPITAL   (Australia)

^c BALLARAT HEALTH SERVICES   (Australia)

^d NONE

Author keywords

Huntington's disease; Monozygotic; Twins

Indexed keywords

ARTICLE; CASE REPORT; CLINICAL FEATURE; CONTROLLED STUDY; ENVIRONMENTAL FACTOR; HUMAN; HUNTINGTON CHOREA; HYPOKINESIA; MALE; MONOZYGOTIC TWINS; MOTOR CONTROL; MOTOR PERFORMANCE; NORMAL HUMAN; PRIORITY JOURNAL;

ADULT; ATTENTION; CASE-CONTROL STUDIES; COGNITION DISORDERS; DISEASE PROGRESSION; ENVIRONMENT; FAMILY HEALTH; HUMANS; HUNTINGTON DISEASE; LONGITUDINAL STUDIES; MALE; MOVEMENT DISORDERS; PERSONALITY; PHENOTYPE; PSYCHOMOTOR PERFORMANCE; SPEECH DISORDERS; TIME AND MOTION STUDIES; TWINS, MONOZYGOTIC; VOLITION;

EID: 0033457954     PISSN: 08853185     EISSN: None     Source Type: Journal    
DOI: 10.1002/1531-8257(199903)14:2<320::AID-MDS1018>3.0.CO;2-Z     Document Type: Article

References (27)

1. Brandt J. Cognitive impairments in Huntington's disease: insights into the neuropsychology of the striatum. In: Boller F, Grafman J, eds. Handbook of Neuropsychology, vol 5. Amsterdam: Elsevier, 1991:241-261.
2. Bradshaw JL, Mattingley JB. Clinical Neuropsychology: Behavioral and Brain Science. London: Academic Press, 1995.
3. Fisher JM, Kennedy JL, Caine ED, Shoulson I. Dementia in Huntington's disease: a cross-sectional analysis of intellectual decline. Adv Neurol 1983;38:229-238.
4. Huntington's Disease Collaborative Research Group. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell 1993;72:971-983.
5. Oliva D, Carella F, Savoiardo M, et al. Clinical and magnetic resonance features of the classic and akinetic-rigid variants of Huntington's disease. Arch Neurol 1993;50:17-19.
6. Alexander GE, Crutcher MD. Functional architecture of the basal ganglia circuits: neural substitutes of parallel processing. Trends Neurosci 1990;13:266-271.
7. Oepen H. Discordant features of monozygotic twin sisters with Huntington's chorea. Adv Neurol 1973;1:199-201.
8. Bird TD, Omenn GS. Monozygotic twins with Huntington's disease in a family expressing the rigid variant. Neurology 1975;25: 1126-1129.
9. Bachman D, Butler I, McKhann G. The long term treatment of juvenile Huntington's chorea with dipropylacetic acid. Neurology 1977;27:193-197.
10. Husquinet H, Franck G, Vranckx C. Detection of future cases of Huntington's chorea by the L-dopa load test: experiment with two monozygotic twins. Adv Neurol 1973;1:301-310.
11. Schiottz-Christensen E. Chorea Huntington and epilepsy in monozygotic twins. Ear Neurol 1969;2:250-255.
12. Harper PS. Huntington's Disease, 2nd ed. London: Saunders Company Ltd, 1996.
13. Kremer B, Goldberg P, Andrew SE, et al. Worldwide study of the Huntington's disease mutation. N Engl J Med 1994;330:1401-1406.
14. Folstein SE. Huntington's Disease: a Disorder of Families. Baltimore, MD: Johns Hopkins University Press, 1989.
15. Kokmen E, Smith GE, Petersen RC, Tangalos E, Ivnik RC. The Short Test of Mental Status: correlations with standardized psychometric testing. Arch Neurol 1991;48:725-728.
16. Yesavage JA, Brink TL, Rose TL, et al. Development and validation of a geriatric depression rating scale: a preliminary report. J Psychiatr Res 1983;17:37-49.
17. Shoulson I, Fahn S. Huntington's disease: clinical care and evaluation. Neurology 1979;29:1-3.
18. Bradshaw JL, Waterfall ML, Phillips JG, Iansek R, Mattingley JB, Bradshaw JA. Re-orientalion of attention in Parkinson's disease: an extension to the vibrotactile modality. Neuropsychologia 1993; 31:51-66.
19. Georgiou N, Bradshaw JL, Phillips JG, Chiu E. The effects of Huntington's disease and Gilles de la Tourette's syndrome on the ability to hold and shift attention. Neuropsychologia 1996;34:843-851.
20. Georgiou G, Phillips JG, Bradshaw JL, Cunnington R, Chiu E. Impairments of movement kinematics in patients with Huntington's disease: a comparison with and without a concurrent task. Mov Disord 1997;12:386-396.
21. Howarth CI, Beggs WDA. The control of simple movements by multisensory information. In: Heuer H, Kleinbeck U, Schmidt KH, eds. Motor Behavior: Programming, Control, and Acquisition. Berlin: Springer-Verlag, 1985:125-151.
22. Bradshaw JL, Howard MJ, Pierson JM, Phillips JG, Bradshaw JA. Effects of expectancy and attention in vibrotactile choice reaction time tasks. Q J Exp Psychol A 1992;44:509-528.
23. Lange HW. Quantitative changes of telecephalon, diencephalon, and mesencephalon in Huntington's chorea, postencephalic, and idiopathic parkinsonisim. Verhandlungen der Anatomischen Gesellschaft 1981;75:923-925.
24. Georgiou N, Bradshaw JL, Phillips JG, Chiu E, Bradshaw JA. Reliance upon advance information and movement sequencing in Huntington's disease. Mov Disord 1995;10:472-481.
25. Feign A, Kieburtz K, Bordwell K, et al. Functional decline in Huntington's disease. Mov Disord 1995;10:211-214.
26. Crow TJ. Schizophrenia as failure of hemispheric dominance for language. Trends Neurosci 1997;20:339-343.
27. Petronis A, Kennedy JL. Unstable genes - unstable mind? Am J Psychiatry 1995;152:164-172.