-
1
-
-
0020533259
-
Obesity as an independent risk factor for cardiovascular disease: A 26-year follow-up of participants in the Framingham Heart Study
-
Hubert, H. B., Feinleib, M., McNamara, P. M. and Castelli, W. P. (1983) Obesity as an independent risk factor for cardiovascular disease: A 26-year follow-up of participants in the Framingham Heart Study. Circulation 67, 968-977.
-
(1983)
Circulation
, vol.67
, pp. 968-977
-
-
Hubert, H.B.1
Feinleib, M.2
McNamara, P.M.3
Castelli, W.P.4
-
2
-
-
17944365228
-
The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity
-
Yamauchi, T., Kamon, J., Waki, H., Terauchi, Y., Kubota, N., Hara, K., Mori, Y., Ide, T., Murakami, K., Tsuboyama-Kasaoka, N., Ezaki, O., Akanuma, Y. et al. (2001) The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat. Med. 7, 941-946.
-
(2001)
Nat. Med
, vol.7
, pp. 941-946
-
-
Yamauchi, T.1
Kamon, J.2
Waki, H.3
Terauchi, Y.4
Kubota, N.5
Hara, K.6
Mori, Y.7
Ide, T.8
Murakami, K.9
Tsuboyama-Kasaoka, N.10
Ezaki, O.11
Akanuma, Y.12
-
3
-
-
19944369735
-
Adiponectin-mediated modulation of hypertrophic signals in the heart
-
Shibata, R., Ouchi, N., Ito, M., Kihara, S., Shiojima, I., Pimentel, D. R., Kumada, M., Sato, K., Schiekofer, S., Ohashi, K., Funahashi, T., Colucci, W. S. and Walsh, K. (2004) Adiponectin-mediated modulation of hypertrophic signals in the heart. Nat. Med. 10, 1384-1389.
-
(2004)
Nat. Med
, vol.10
, pp. 1384-1389
-
-
Shibata, R.1
Ouchi, N.2
Ito, M.3
Kihara, S.4
Shiojima, I.5
Pimentel, D.R.6
Kumada, M.7
Sato, K.8
Schiekofer, S.9
Ohashi, K.10
Funahashi, T.11
Colucci, W.S.12
Walsh, K.13
-
4
-
-
0032577404
-
Environmental contributions to the obesity epidemic
-
Hill, J. O. and Peters, J. C. (1998) Environmental contributions to the obesity epidemic. Science 280, 1371-1374.
-
(1998)
Science
, vol.280
, pp. 1371-1374
-
-
Hill, J.O.1
Peters, J.C.2
-
5
-
-
33749017409
-
-
Rankinen, T., Zuberi, A., Chagnon, Y. C., Weisnagel, S. J., Argyropoulos, G., Walts, B., Pérusse, L. and Bouchard, C. (2006) The human obesity gene map: The 2005 update. Obesity (Silver Spring) 14, 529-644.
-
Rankinen, T., Zuberi, A., Chagnon, Y. C., Weisnagel, S. J., Argyropoulos, G., Walts, B., Pérusse, L. and Bouchard, C. (2006) The human obesity gene map: The 2005 update. Obesity (Silver Spring) 14, 529-644.
-
-
-
-
6
-
-
14344266748
-
The genetics of human obesity
-
Bell, C. G., Walley, A. J. and Froguel, P. (2005) The genetics of human obesity. Nat. Rev. Genet. 6, 221-234.
-
(2005)
Nat. Rev. Genet
, vol.6
, pp. 221-234
-
-
Bell, C.G.1
Walley, A.J.2
Froguel, P.3
-
7
-
-
0029089898
-
The human obese (OB) gene: RNA expression pattern and mapping on the physical, cytogenetic, and genetic maps of chromosome 7
-
Green, E. D., Maffei, M., Braden, V. V., Proenca, R., DeSilva, U., Zhang, Y., Chua, S. C. Jr., Leibel, R. L., Weissenbach, J. and Friedman, J. M. (1995) The human obese (OB) gene: RNA expression pattern and mapping on the physical, cytogenetic, and genetic maps of chromosome 7. Genome Res. 5, 5-12.
-
(1995)
Genome Res
, vol.5
, pp. 5-12
-
-
Green, E.D.1
Maffei, M.2
Braden, V.V.3
Proenca, R.4
DeSilva, U.5
Zhang, Y.6
Chua Jr., S.C.7
Leibel, R.L.8
Weissenbach, J.9
Friedman, J.M.10
-
8
-
-
0028139089
-
Positional cloning of the mouse obese gene and its human homologue
-
Zhang, Y., Proenca, R., Maffei, M., Barone, M., Leopold, L. and Friedman, J. M. (1994) Positional cloning of the mouse obese gene and its human homologue. Nature 372, 425-432.
-
(1994)
Nature
, vol.372
, pp. 425-432
-
-
Zhang, Y.1
Proenca, R.2
Maffei, M.3
Barone, M.4
Leopold, L.5
Friedman, J.M.6
-
9
-
-
0029020677
-
Evidence against either a premature stop codon or the absence of obese gene mRNA in human obesity
-
Considine, R. V., Considine, E. L., Williams, C. J., Nyce, M. R., Magosin, S. A., Bauer, T. L., Rosato, E. L., Colberg, J. and Caro, J. F. (1995) Evidence against either a premature stop codon or the absence of obese gene mRNA in human obesity. J. Clin. Invest. 95, 2986-2988.
-
(1995)
J. Clin. Invest
, vol.95
, pp. 2986-2988
-
-
Considine, R.V.1
Considine, E.L.2
Williams, C.J.3
Nyce, M.R.4
Magosin, S.A.5
Bauer, T.L.6
Rosato, E.L.7
Colberg, J.8
Caro, J.F.9
-
10
-
-
0030878110
-
Congenital leptin deficiency is associated with severe early-onset obesity in humans
-
Montague, C. T., Farooqi, I. S., Whitehead, J. P., Soos, M. A., Rau, H., Wareham, N. J., Sewter, C. P., Digby, J. E., Mohammed, S. N., Hurst, J. A., Cheetham, C. H., Earley, A. R. et al. (1997) Congenital leptin deficiency is associated with severe early-onset obesity in humans. Nature 387, 903-908.
-
(1997)
Nature
, vol.387
, pp. 903-908
-
-
Montague, C.T.1
Farooqi, I.S.2
Whitehead, J.P.3
Soos, M.A.4
Rau, H.5
Wareham, N.J.6
Sewter, C.P.7
Digby, J.E.8
Mohammed, S.N.9
Hurst, J.A.10
Cheetham, C.H.11
Earley, A.R.12
-
11
-
-
0030006511
-
Mapping of the OB receptor to 1p in a region of nonconserved gene order from mouse and rat to human
-
Chung, W. K., Power-Kehoe, L., Chua, M. and Leibel, R. L. (1996) Mapping of the OB receptor to 1p in a region of nonconserved gene order from mouse and rat to human. Genome Res. 6, 431-438.
-
(1996)
Genome Res
, vol.6
, pp. 431-438
-
-
Chung, W.K.1
Power-Kehoe, L.2
Chua, M.3
Leibel, R.L.4
-
12
-
-
13344259300
-
Evidence that the diabetes gene encodes the leptin receptor: Identification of a mutation in the leptin receptor gene in db/db mice
-
Chen, H., Charlat, O., Tartaglia, L. A., Woolf, E. A., Weng, X., Ellis, S. J., Lakey, N. D., Culpepper, J., Moore, K. J., Breitbart, R. E., Duyk, G. M., Tepper, R. I. et al. (1996) Evidence that the diabetes gene encodes the leptin receptor: Identification of a mutation in the leptin receptor gene in db/db mice. Cell 84, 491-495.
-
(1996)
Cell
, vol.84
, pp. 491-495
-
-
Chen, H.1
Charlat, O.2
Tartaglia, L.A.3
Woolf, E.A.4
Weng, X.5
Ellis, S.J.6
Lakey, N.D.7
Culpepper, J.8
Moore, K.J.9
Breitbart, R.E.10
Duyk, G.M.11
Tepper, R.I.12
-
13
-
-
0030039272
-
Abnormal splicing of the leptin receptor in diabetic mice
-
Lee, G. H., Proenca, R., Montez, J. M., Carroll, K. M., Darvishzadeh, J. G., Lee, J. I. and Friedman, J. M. (1996) Abnormal splicing of the leptin receptor in diabetic mice. Nature 379, 632-635.
-
(1996)
Nature
, vol.379
, pp. 632-635
-
-
Lee, G.H.1
Proenca, R.2
Montez, J.M.3
Carroll, K.M.4
Darvishzadeh, J.G.5
Lee, J.I.6
Friedman, J.M.7
-
14
-
-
0029895421
-
Phenotype-linked amino acid alteration in leptin receptor cDNA from Zucker fatty (fa/fa) rat
-
Iida, M., Murakami, T., Ishida, K., Mizuno, A., Kuwajima, M. and Shima, K. (1996) Phenotype-linked amino acid alteration in leptin receptor cDNA from Zucker fatty (fa/fa) rat. Biochem. Biophys. Res. Commun. 222, 19-26.
-
(1996)
Biochem. Biophys. Res. Commun
, vol.222
, pp. 19-26
-
-
Iida, M.1
Murakami, T.2
Ishida, K.3
Mizuno, A.4
Kuwajima, M.5
Shima, K.6
-
15
-
-
0344450708
-
A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction
-
Clément, K., Vaisse, C., Lahlou, N., Cabrol, S., Pelloux, V., Cassuto, D., Gourmelen, M., Dina, C., Chambaz, J., Lacorte, J. M., Basdevant, A., Bougneres, P. et al. (1998) A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction. Nature 392, 398-401.
-
(1998)
Nature
, vol.392
, pp. 398-401
-
-
Clément, K.1
Vaisse, C.2
Lahlou, N.3
Cabrol, S.4
Pelloux, V.5
Cassuto, D.6
Gourmelen, M.7
Dina, C.8
Chambaz, J.9
Lacorte, J.M.10
Basdevant, A.11
Bougneres, P.12
-
16
-
-
0011819393
-
-
Zabel, B. U., Naylor, S. L., Sakaguchi, A. Y., Bell, G. I. and Shows, T. B. (1983) High-resolution chromosomal localization of human genes for amylase, proopiomelanocortin, somatostatin, and a DNA fragment (D3S1) by in situ hybridization. Proc. Nat. Acad. Sci. USA 80, 6932-6936.
-
Zabel, B. U., Naylor, S. L., Sakaguchi, A. Y., Bell, G. I. and Shows, T. B. (1983) High-resolution chromosomal localization of human genes for amylase, proopiomelanocortin, somatostatin, and a DNA fragment (D3S1) by in situ hybridization. Proc. Nat. Acad. Sci. USA 80, 6932-6936.
-
-
-
-
17
-
-
0031838353
-
Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans
-
Krude, H., Biebermann, H., Luck, W., Horn, R., Brabant, G. and Grüters, A. (1998) Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans. Nat. Genet. 19, 155-157.
-
(1998)
Nat. Genet
, vol.19
, pp. 155-157
-
-
Krude, H.1
Biebermann, H.2
Luck, W.3
Horn, R.4
Brabant, G.5
Grüters, A.6
-
18
-
-
0242320429
-
Obesity due to proopiomelanocortin deficiency: Three new cases and treatment trials with thyroid hormone and ACTH4-10
-
Krude, H., Biebermann, H., Schnabel, D., Tansek, M. Z., Theunissen, P., Mullis, P. E. and Grüters, A. (2003) Obesity due to proopiomelanocortin deficiency: Three new cases and treatment trials with thyroid hormone and ACTH4-10. J. Clin. Endocrinol. Metab. 88, 4633-4640.
-
(2003)
J. Clin. Endocrinol. Metab
, vol.88
, pp. 4633-4640
-
-
Krude, H.1
Biebermann, H.2
Schnabel, D.3
Tansek, M.Z.4
Theunissen, P.5
Mullis, P.E.6
Grüters, A.7
-
19
-
-
33750592655
-
Heterozygosity for a POMC-null mutation and increased obesity risk in humans
-
Farooqi, I. S., Drop, S., Clements, A., Keogh, J. M., Biernacka, J., Lowenbein, S., Challis, B. G. and O'Rahilly, S. (2006) Heterozygosity for a POMC-null mutation and increased obesity risk in humans. Diabetes 55, 2549-2553.
-
(2006)
Diabetes
, vol.55
, pp. 2549-2553
-
-
Farooqi, I.S.1
Drop, S.2
Clements, A.3
Keogh, J.M.4
Biernacka, J.5
Lowenbein, S.6
Challis, B.G.7
O'Rahilly, S.8
-
20
-
-
0030889192
-
Targeted disruption of the melanocortin-4 receptor results in obesity in mice
-
Huszar, D., Lynch, C. A., Fairchild-Huntress, V., Dunmore, J. H., Fang, Q., Berkemeier, L. R., Gu, W., Kesterson, R. A., Boston, B. A., Cone, R. D., Smith, F. J., Campfield, L. A. et al. (1997) Targeted disruption of the melanocortin-4 receptor results in obesity in mice. Cell 88, 131-141.
-
(1997)
Cell
, vol.88
, pp. 131-141
-
-
Huszar, D.1
Lynch, C.A.2
Fairchild-Huntress, V.3
Dunmore, J.H.4
Fang, Q.5
Berkemeier, L.R.6
Gu, W.7
Kesterson, R.A.8
Boston, B.A.9
Cone, R.D.10
Smith, F.J.11
Campfield, L.A.12
-
21
-
-
0031668219
-
A frameshift mutation in MC4R associated with dominantly inherited human obesity
-
Yeo, G. S., Farooqi, I. S., Aminian, S., Halsall, D. J., Stanhope, R. G. and O'Rahilly, S. (1998) A frameshift mutation in MC4R associated with dominantly inherited human obesity. Nat. Genet. 20, 111-112.
-
(1998)
Nat. Genet
, vol.20
, pp. 111-112
-
-
Yeo, G.S.1
Farooqi, I.S.2
Aminian, S.3
Halsall, D.J.4
Stanhope, R.G.5
O'Rahilly, S.6
-
22
-
-
0031662163
-
A frameshift mutation in human MC4R is associated with a dominant form of obesity
-
Vaisse, C., Clement, K., Guy-Grand, B. and Froguel, P. (1998) A frameshift mutation in human MC4R is associated with a dominant form of obesity. Nat. Genet. 20, 113-114.
-
(1998)
Nat. Genet
, vol.20
, pp. 113-114
-
-
Vaisse, C.1
Clement, K.2
Guy-Grand, B.3
Froguel, P.4
-
23
-
-
0034913118
-
A novel melanocortin 4 receptor (MC4R) gene mutation associated with morbid obesity
-
Mergen, M., Mergen, H., Ozata, M., Oner, R. and Oner, C. (2001) A novel melanocortin 4 receptor (MC4R) gene mutation associated with morbid obesity. J. Clin. Endocrinol. Metab. 86, 3448.
-
(2001)
J. Clin. Endocrinol. Metab
, vol.86
, pp. 3448
-
-
Mergen, M.1
Mergen, H.2
Ozata, M.3
Oner, R.4
Oner, C.5
-
24
-
-
0036094522
-
A novel homozygous missense mutation of melanocortin-4 receptor (MC4R) in a Japanese woman with severe obesity
-
Kobayashi, H., Ogawa, Y., Shintani, M., Ebihara, K., Shimodahira, M., Iwakura, T., Hino, M., Ishihara, T., Ikekubo, K., Kurahachi, H. and Nakao, K. (2002) A novel homozygous missense mutation of melanocortin-4 receptor (MC4R) in a Japanese woman with severe obesity. Diabetes 51, 243-246.
-
(2002)
Diabetes
, vol.51
, pp. 243-246
-
-
Kobayashi, H.1
Ogawa, Y.2
Shintani, M.3
Ebihara, K.4
Shimodahira, M.5
Iwakura, T.6
Hino, M.7
Ishihara, T.8
Ikekubo, K.9
Kurahachi, H.10
Nakao, K.11
-
25
-
-
0030949271
-
Obesity and impaired prohormone processing associated with mutations in the human prohormone convertase 1 gene
-
Jackson, R. S., Creemers, J. W., Ohagi, S., Raffin-Sanson, M. L., Sanders, L., Montague, C. T., Hutton, J. C. and O'Rahilly, S. (1997) Obesity and impaired prohormone processing associated with mutations in the human prohormone convertase 1 gene. Nat. Genet. 16, 303-306.
-
(1997)
Nat. Genet
, vol.16
, pp. 303-306
-
-
Jackson, R.S.1
Creemers, J.W.2
Ohagi, S.3
Raffin-Sanson, M.L.4
Sanders, L.5
Montague, C.T.6
Hutton, J.C.7
O'Rahilly, S.8
-
26
-
-
0346096721
-
Small-intestinal dysfunction accompanies the complex endocrinopathy of human proprotein convertase 1 deficiency
-
Jackson, R. S., Creemers, J. W., Farooqi, I. S., Raffin-Sanson, M. L., Varro, A., Dockray, G. J., Holst, J. J., Brubaker, P. L., Corvol, P., Polonsky, K. S., Ostrega, D., Becker, K. L. et al. (2003) Small-intestinal dysfunction accompanies the complex endocrinopathy of human proprotein convertase 1 deficiency. J. Clin. Invest. 112, 1550-1560.
-
(2003)
J. Clin. Invest
, vol.112
, pp. 1550-1560
-
-
Jackson, R.S.1
Creemers, J.W.2
Farooqi, I.S.3
Raffin-Sanson, M.L.4
Varro, A.5
Dockray, G.J.6
Holst, J.J.7
Brubaker, P.L.8
Corvol, P.9
Polonsky, K.S.10
Ostrega, D.11
Becker, K.L.12
-
27
-
-
0034016043
-
Profound obesity associated with a balanced translocation that disrupts the SIM1 gene
-
Holder, J. L. Jr., Butte, N. F. and Zinn, A. R. (2000) Profound obesity associated with a balanced translocation that disrupts the SIM1 gene. Hum. Mol. Genet. 9, 101-108.
-
(2000)
Hum. Mol. Genet
, vol.9
, pp. 101-108
-
-
Holder Jr., J.L.1
Butte, N.F.2
Zinn, A.R.3
-
28
-
-
0035393437
-
Sim1 haploinsufficiency causes hyperphagia, obesity and reduction of the paraventricular nucleus of the hypothalamus
-
Michaud, J. L., Boucher, F., Melnyk, A., Gauthier, F., Goshu, E., Lévy, E., Mitchell, G. A., Himms-Hagen, J. and Fan, C. M. (2001) Sim1 haploinsufficiency causes hyperphagia, obesity and reduction of the paraventricular nucleus of the hypothalamus. Hum. Mol. Genet. 10, 1465-1473.
-
(2001)
Hum. Mol. Genet
, vol.10
, pp. 1465-1473
-
-
Michaud, J.L.1
Boucher, F.2
Melnyk, A.3
Gauthier, F.4
Goshu, E.5
Lévy, E.6
Mitchell, G.A.7
Himms-Hagen, J.8
Fan, C.M.9
-
29
-
-
7044262828
-
A de novo mutation affecting human TrkB associated with severe obesity and developmental delay
-
Yeo, G. S., Connie Hung, C. C., Rochford, J., Keogh, J., Gray, J., Sivaramakrishnan, S., O'Rahilly, S. and Farooqi, I. S. (2004) A de novo mutation affecting human TrkB associated with severe obesity and developmental delay. Nat. Neurosci. 7, 1187-1189.
-
(2004)
Nat. Neurosci
, vol.7
, pp. 1187-1189
-
-
Yeo, G.S.1
Connie Hung, C.C.2
Rochford, J.3
Keogh, J.4
Gray, J.5
Sivaramakrishnan, S.6
O'Rahilly, S.7
Farooqi, I.S.8
-
30
-
-
0038392755
-
Brain-derived neurotrophic factor regulates energy balance downstream of melanocortin-4 receptor
-
Xu, B., Goulding, E. H., Zang, K., Cepoi, D., Cone, R. D., Jones, K. R., Tecott, L. H. and Reichardt, L. F. (2003) Brain-derived neurotrophic factor regulates energy balance downstream of melanocortin-4 receptor. Nat. Neurosci. 6, 736-742.
-
(2003)
Nat. Neurosci
, vol.6
, pp. 736-742
-
-
Xu, B.1
Goulding, E.H.2
Zang, K.3
Cepoi, D.4
Cone, R.D.5
Jones, K.R.6
Tecott, L.H.7
Reichardt, L.F.8
-
31
-
-
23044467704
-
Molecular physiology of syndromic obesities in humans
-
Chung, W. K. and Leibel, R. L. (2005) Molecular physiology of syndromic obesities in humans. Trends Endocrinol. Metab. 16, 267-272.
-
(2005)
Trends Endocrinol. Metab
, vol.16
, pp. 267-272
-
-
Chung, W.K.1
Leibel, R.L.2
-
32
-
-
0035515362
-
The changing purpose of Prader-Willi syndrome clinical diagnostic criteria and proposed revised criteria
-
Gunay-Aygun, M., Schwartz, S., Heeger, S., O'Riordan, M. A. and Cassidy, S. B. (2001) The changing purpose of Prader-Willi syndrome clinical diagnostic criteria and proposed revised criteria. Pediatrics 108, E92.
-
(2001)
Pediatrics
, vol.108
-
-
Gunay-Aygun, M.1
Schwartz, S.2
Heeger, S.3
O'Riordan, M.A.4
Cassidy, S.B.5
-
33
-
-
33645455075
-
Imprinting defects on human chromosome 15
-
Horsthemke, B. and Buiting, K. (2006) Imprinting defects on human chromosome 15. Cytogenet. Genome Res. 113, 292-299.
-
(2006)
Cytogenet. Genome Res
, vol.113
, pp. 292-299
-
-
Horsthemke, B.1
Buiting, K.2
-
34
-
-
0035777024
-
Genome organization, function, and imprinting in Prader-Willi and Angelman syndromes
-
Nicholls, R. D. and Knepper, J. L. (2001) Genome organization, function, and imprinting in Prader-Willi and Angelman syndromes. Annu. Rev. Genomics Hum. Genet. 2, 153-175.
-
(2001)
Annu. Rev. Genomics Hum. Genet
, vol.2
, pp. 153-175
-
-
Nicholls, R.D.1
Knepper, J.L.2
-
35
-
-
16944363776
-
The human necdin gene, NDN, is maternally imprinted and located in the Prader-Willi syndrome chromosomal region
-
Jay, P., Rougeulle, C., Massacrier, A., Moncla, A., Mattei, M. G., Malzac, P., Roëckel, N., Taviaux, S., Lefranc, J. L., Cau, P., Berta, P., Lalande, M. and Muscatelli, F. (1997) The human necdin gene, NDN, is maternally imprinted and located in the Prader-Willi syndrome chromosomal region. Nat. Genet. 17, 357-361.
-
(1997)
Nat. Genet
, vol.17
, pp. 357-361
-
-
Jay, P.1
Rougeulle, C.2
Massacrier, A.3
Moncla, A.4
Mattei, M.G.5
Malzac, P.6
Roëckel, N.7
Taviaux, S.8
Lefranc, J.L.9
Cau, P.10
Berta, P.11
Lalande, M.12
Muscatelli, F.13
-
36
-
-
0035509699
-
The IC-SNURF-SNRPN transcript serves as a host for multiple small nucleolar RNA species and as an antisense RNA for UBE3A
-
Runte, M., Hüttenhofer, A., Gross, S., Kiefmann, M., Horsthemke, B. and Buiting, K. (2001) The IC-SNURF-SNRPN transcript serves as a host for multiple small nucleolar RNA species and as an antisense RNA for UBE3A. Hum. Mol. Genet. 10, 2687-2700.
-
(2001)
Hum. Mol. Genet
, vol.10
, pp. 2687-2700
-
-
Runte, M.1
Hüttenhofer, A.2
Gross, S.3
Kiefmann, M.4
Horsthemke, B.5
Buiting, K.6
-
37
-
-
0033951792
-
Interstitial 6q deletion with a Prader-Willi-like phenotype:Anew case and review of the literature
-
Gilhuis, H. J., van Ravenswaaij, C. M., Hamel, B. J. and Gabreëls, F. J. (2000) Interstitial 6q deletion with a Prader-Willi-like phenotype:Anew case and review of the literature. Eur. J. Paediatr. Neurol. 4, 39-43.
-
(2000)
Eur. J. Paediatr. Neurol
, vol.4
, pp. 39-43
-
-
Gilhuis, H.J.1
van Ravenswaaij, C.M.2
Hamel, B.J.3
Gabreëls, F.J.4
-
38
-
-
0033062278
-
New criteria for improved diagnosis of Bardet-Biedl syndrome: Results of a population survey
-
Beales, P. L., Elcioglu, N., Woolf, A. S., Parker, D. and Flinter, F. A. (1999) New criteria for improved diagnosis of Bardet-Biedl syndrome: Results of a population survey. J. Med. Genet. 36, 437-446.
-
(1999)
J. Med. Genet
, vol.36
, pp. 437-446
-
-
Beales, P.L.1
Elcioglu, N.2
Woolf, A.S.3
Parker, D.4
Flinter, F.A.5
-
39
-
-
0031040854
-
Bardet-Biedl syndrome:Amolecular and phenotypic study of 18 families
-
Beales, P. L., Warner, A. M., Hitman, G. A., Thakker, R. and Flinter, F. A. (1997) Bardet-Biedl syndrome:Amolecular and phenotypic study of 18 families. J. Med. Genet. 34, 92-98.
-
(1997)
J. Med. Genet
, vol.34
, pp. 92-98
-
-
Beales, P.L.1
Warner, A.M.2
Hitman, G.A.3
Thakker, R.4
Flinter, F.A.5
-
40
-
-
33646354641
-
BBS10 encodes a vertebrate-specific chaperonin-like protein and is a major BBS locus
-
Stoetzel, C., Laurier, V., Davis, E. E., Muller, J., Rix, S., Badano, J. L., Leitch, C. C., Salem, N., Chouery, E., Corbani, S., Jalk, N., Vicaire, S. et al. (2006) BBS10 encodes a vertebrate-specific chaperonin-like protein and is a major BBS locus. Nat. Genet. 38, 521-524.
-
(2006)
Nat. Genet
, vol.38
, pp. 521-524
-
-
Stoetzel, C.1
Laurier, V.2
Davis, E.E.3
Muller, J.4
Rix, S.5
Badano, J.L.6
Leitch, C.C.7
Salem, N.8
Chouery, E.9
Corbani, S.10
Jalk, N.11
Vicaire, S.12
-
41
-
-
33646562887
-
Homozygosity mapping with SNP arrays identifies TRIM32, an E3 ubiquitin ligase, as a Bardet-Biedl syndrome gene (BBS11)
-
Chiang, A. P., Beck, J. S., Yen, H. J., Tayeh, M. K., Scheetz, T. E., Swiderski, R. E., Nishimura, D. Y., Braun, T. A., Kim, K. Y., Huang, J., Elbedour, K., Carmi, R. et al. (2006) Homozygosity mapping with SNP arrays identifies TRIM32, an E3 ubiquitin ligase, as a Bardet-Biedl syndrome gene (BBS11). Proc. Natl. Acad. Sci. USA 103, 6287-6292.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 6287-6292
-
-
Chiang, A.P.1
Beck, J.S.2
Yen, H.J.3
Tayeh, M.K.4
Scheetz, T.E.5
Swiderski, R.E.6
Nishimura, D.Y.7
Braun, T.A.8
Kim, K.Y.9
Huang, J.10
Elbedour, K.11
Carmi, R.12
-
42
-
-
33845995129
-
Identification of a novel BBS gene (BBS12) highlights the major role of a vertebrate-specific branch of chaperonin-related proteins in Bardet-Biedl syndrome
-
Stoetzel, C., Muller, J., Laurier, V., Davis, E. E., Zaghloul, N. A., Vicaire, S., Jacquelin, C., Plewniak, F., Leitch, C. C., Sarda, P., Hamel, C., deRavel, T. J. et al. (2007) Identification of a novel BBS gene (BBS12) highlights the major role of a vertebrate-specific branch of chaperonin-related proteins in Bardet-Biedl syndrome. Am. J. Hum. Genet. 80, 1-11.
-
(2007)
Am. J. Hum. Genet
, vol.80
, pp. 1-11
-
-
Stoetzel, C.1
Muller, J.2
Laurier, V.3
Davis, E.E.4
Zaghloul, N.A.5
Vicaire, S.6
Jacquelin, C.7
Plewniak, F.8
Leitch, C.C.9
Sarda, P.10
Hamel, C.11
deRavel, T.J.12
-
43
-
-
0035929273
-
Triallelic inheritance in Bardet-Biedl syndrome, a Mendelian recessive disorder
-
Katsanis, N., Ansley, S. J., Badano, J. L., Eichers, E. R., Lewis, R. A., Hoskins, B. E., Scambler, P. J., Davidson, W. S., Beales, P. L. and Lupski, J. R. (2001) Triallelic inheritance in Bardet-Biedl syndrome, a Mendelian recessive disorder. Science 293, 2256-2259.
-
(2001)
Science
, vol.293
, pp. 2256-2259
-
-
Katsanis, N.1
Ansley, S.J.2
Badano, J.L.3
Eichers, E.R.4
Lewis, R.A.5
Hoskins, B.E.6
Scambler, P.J.7
Davidson, W.S.8
Beales, P.L.9
Lupski, J.R.10
-
44
-
-
4444291840
-
Mutations in a member of the Ras superfamily of small GTP-binding proteins causes Bardet-Biedl syndrome
-
Fan, Y., Esmail, M. A., Ansley, S. J., Blacque, O. E., Boroevich, K., Ross, A. J., Moore, S. J., Badano, J. L., May-Simera, H., Compton, D. S., Green, J. S., Lewis, R. A. et al. (2004) Mutations in a member of the Ras superfamily of small GTP-binding proteins causes Bardet-Biedl syndrome. Nat. Genet. 36, 989-993.
-
(2004)
Nat. Genet
, vol.36
, pp. 989-993
-
-
Fan, Y.1
Esmail, M.A.2
Ansley, S.J.3
Blacque, O.E.4
Boroevich, K.5
Ross, A.J.6
Moore, S.J.7
Badano, J.L.8
May-Simera, H.9
Compton, D.S.10
Green, J.S.11
Lewis, R.A.12
-
45
-
-
0037322689
-
Evaluation of complex inheritance involving the most common Bardet-Biedl syndrome locus (BBS1)
-
Mykytyn, K., Nishimura, D. Y., Searby, C. C., Beck, G., Bugge, K., Haines, H. L., Cornier, A. S., Cox, G. F., Fulton, A. B., Carmi, R., Iannaccone, A., Jacobson, S. G. et al. (2003) Evaluation of complex inheritance involving the most common Bardet-Biedl syndrome locus (BBS1). Am. J. Hum. Genet. 72, 429-437.
-
(2003)
Am. J. Hum. Genet
, vol.72
, pp. 429-437
-
-
Mykytyn, K.1
Nishimura, D.Y.2
Searby, C.C.3
Beck, G.4
Bugge, K.5
Haines, H.L.6
Cornier, A.S.7
Cox, G.F.8
Fulton, A.B.9
Carmi, R.10
Iannaccone, A.11
Jacobson, S.G.12
-
46
-
-
0033812186
-
Mutations in MKKS cause Bardet-Biedl syndrome
-
Slavotinek, A. M., Stone, E. M., Mykytyn, K., Heckenlively, J. R., Green, J. S., Heon, E., Musarella, M. A., Parfrey, P. S., Sheffield, V. C. and Biesecker, L. G. (2000) Mutations in MKKS cause Bardet-Biedl syndrome. Nat. Genet. 26, 15-16.
-
(2000)
Nat. Genet
, vol.26
, pp. 15-16
-
-
Slavotinek, A.M.1
Stone, E.M.2
Mykytyn, K.3
Heckenlively, J.R.4
Green, J.S.5
Heon, E.6
Musarella, M.A.7
Parfrey, P.S.8
Sheffield, V.C.9
Biesecker, L.G.10
-
47
-
-
0033822064
-
Mutations in MKKS cause obesity, retinal dystrophy and renal malformations associated with Bardet-Biedl syndrome
-
Katsanis, N., Beales, P. L., Woods, M. O., Lewis, R. A., Green, J. S., Parfrey, P. S., Ansley, S. J., Davidson, W. S. and Lupski, J. R. (2000) Mutations in MKKS cause obesity, retinal dystrophy and renal malformations associated with Bardet-Biedl syndrome. Nat. Genet. 26, 67-70.
-
(2000)
Nat. Genet
, vol.26
, pp. 67-70
-
-
Katsanis, N.1
Beales, P.L.2
Woods, M.O.3
Lewis, R.A.4
Green, J.S.5
Parfrey, P.S.6
Ansley, S.J.7
Davidson, W.S.8
Lupski, J.R.9
-
48
-
-
28144460266
-
Comparative genomics and gene expression analysis identifies BBS9, a new Bardet-Biedl syndrome gene
-
Nishimura, D. Y., Swiderski, R. E., Searby, C. C., Berg, E. M., Ferguson, A. L., Hennekam, R., Merin, S., Weleber, R. G., Biesecker, L. G., Stone, E. M. and Sheffield, V. C. (2005) Comparative genomics and gene expression analysis identifies BBS9, a new Bardet-Biedl syndrome gene. Am. J. Hum. Genet. 77, 1021-1033.
-
(2005)
Am. J. Hum. Genet
, vol.77
, pp. 1021-1033
-
-
Nishimura, D.Y.1
Swiderski, R.E.2
Searby, C.C.3
Berg, E.M.4
Ferguson, A.L.5
Hennekam, R.6
Merin, S.7
Weleber, R.G.8
Biesecker, L.G.9
Stone, E.M.10
Sheffield, V.C.11
-
49
-
-
0142104970
-
Basal body dysfunction is a likely cause of pleiotropic Bardet-Biedl syndrome
-
Ansley, S. J., Badano, J. L., Blacque, O. E., Hill, J., Hoskins, B. E., Leitch, C. C., Kim, J. C., Ross, A. J., Eichers, E. R., Teslovich, T. M., Mah, A. K., Johnsen, R. C. et al. (2003) Basal body dysfunction is a likely cause of pleiotropic Bardet-Biedl syndrome. Nature 425, 628-633.
-
(2003)
Nature
, vol.425
, pp. 628-633
-
-
Ansley, S.J.1
Badano, J.L.2
Blacque, O.E.3
Hill, J.4
Hoskins, B.E.5
Leitch, C.C.6
Kim, J.C.7
Ross, A.J.8
Eichers, E.R.9
Teslovich, T.M.10
Mah, A.K.11
Johnsen, R.C.12
-
50
-
-
0030732665
-
Genealogy, natural history, and phenotype of Alstrom syndrome in a large Acadian kindred and three additional families
-
Marshall, J. D., Ludman, M. D., Shea, S. E., Salisbury, S. R., Willi, S. M., LaRoche, R. G. and Nishina, P. M. (1997) Genealogy, natural history, and phenotype of Alstrom syndrome in a large Acadian kindred and three additional families. Am. J. Med. Genet. 73, 150-161.
-
(1997)
Am. J. Med. Genet
, vol.73
, pp. 150-161
-
-
Marshall, J.D.1
Ludman, M.D.2
Shea, S.E.3
Salisbury, S.R.4
Willi, S.M.5
LaRoche, R.G.6
Nishina, P.M.7
-
51
-
-
0036578890
-
Mutations in ALMS1 cause obesity, type 2 diabetes and neurosensory degeneration in Alstrom syndrome
-
Collin, G. B., Marshall, J. D., Ikeda, A., So, W. V., Russell-Eggitt, I., Maffei, P., Beck, S., Boerkoel, C. F., Sicolo, N., Martin, M., Nishina, P. M. and Naggert, J. K. (2002) Mutations in ALMS1 cause obesity, type 2 diabetes and neurosensory degeneration in Alstrom syndrome. Nat. Genet. 31, 74-78.
-
(2002)
Nat. Genet
, vol.31
, pp. 74-78
-
-
Collin, G.B.1
Marshall, J.D.2
Ikeda, A.3
So, W.V.4
Russell-Eggitt, I.5
Maffei, P.6
Beck, S.7
Boerkoel, C.F.8
Sicolo, N.9
Martin, M.10
Nishina, P.M.11
Naggert, J.K.12
-
52
-
-
18544391142
-
Mutation of ALMS1, a large gene with a tandem repeat encoding 47 amino acids, causes Alstrom syndrome
-
Hearn, T., Renforth, G. L., Spalluto, C., Hanley, N. A., Piper, K., Brickwood, S., White, C., Connolly, V., Taylor, J. F., Russell-Eggitt, I., Bonneau, D., Walker, M. et al. (2002) Mutation of ALMS1, a large gene with a tandem repeat encoding 47 amino acids, causes Alstrom syndrome. Nat. Genet. 31, 79-83.
-
(2002)
Nat. Genet
, vol.31
, pp. 79-83
-
-
Hearn, T.1
Renforth, G.L.2
Spalluto, C.3
Hanley, N.A.4
Piper, K.5
Brickwood, S.6
White, C.7
Connolly, V.8
Taylor, J.F.9
Russell-Eggitt, I.10
Bonneau, D.11
Walker, M.12
-
53
-
-
0022635231
-
The Borjeson-Forssman-Lehmann syndrome. A family study
-
Dereymaeker, A. M., Fryns, J. P., Hoefnagels, M., Heremans, G., Marien, J. and van den Berghe, H. (1986) The Borjeson-Forssman-Lehmann syndrome. A family study. Clin. Genet. 29, 317-320.
-
(1986)
Clin. Genet
, vol.29
, pp. 317-320
-
-
Dereymaeker, A.M.1
Fryns, J.P.2
Hoefnagels, M.3
Heremans, G.4
Marien, J.5
van den Berghe, H.6
-
54
-
-
10744219685
-
The clinical picture of the Börjeson-Forssman- Lehmann syndrome in males and heterozygous females with PHF6 mutations
-
Turner, G., Lower, K. M., White, S. M., Delatycki, M., Lampe, A. K., Wright, M., Smith, J. C., Kerr, B., Schelley, S., Hoyme, H. E., De Vries, B. B., Kleefstra, T. et al. (2004) The clinical picture of the Börjeson-Forssman- Lehmann syndrome in males and heterozygous females with PHF6 mutations. Clin. Genet. 65, 226-232.
-
(2004)
Clin. Genet
, vol.65
, pp. 226-232
-
-
Turner, G.1
Lower, K.M.2
White, S.M.3
Delatycki, M.4
Lampe, A.K.5
Wright, M.6
Smith, J.C.7
Kerr, B.8
Schelley, S.9
Hoyme, H.E.10
De Vries, B.B.11
Kleefstra, T.12
-
55
-
-
0024854232
-
Börjeson-Forssman-Lehmann syndrome: Clinical manifestations and gene localization to Xq26-27
-
Turner, G., Gedeon, A., Mulley, J., Sutherland, G., Rae, J., Power, K. and Arthur, I. (1989) Börjeson-Forssman-Lehmann syndrome: Clinical manifestations and gene localization to Xq26-27. Am. J. Med. Genet. 34, 463-469.
-
(1989)
Am. J. Med. Genet
, vol.34
, pp. 463-469
-
-
Turner, G.1
Gedeon, A.2
Mulley, J.3
Sutherland, G.4
Rae, J.5
Power, K.6
Arthur, I.7
-
56
-
-
18744393073
-
Mutations in PHF6 are associated with Börjeson-Forssman-Lehmann syndrome
-
Lower, K. M., Turner, G., Kerr, B. A., Mathews, K. D., Shaw, M. A., Gedeon, A. K., Schelley, S., Hoyme, H. E., White, S. M., Delatycki, M. B., Lampe, A. K., Clayton-Smith, J. et al. (2002) Mutations in PHF6 are associated with Börjeson-Forssman-Lehmann syndrome. Nat. Genet. 32, 661-665.
-
(2002)
Nat. Genet
, vol.32
, pp. 661-665
-
-
Lower, K.M.1
Turner, G.2
Kerr, B.A.3
Mathews, K.D.4
Shaw, M.A.5
Gedeon, A.K.6
Schelley, S.7
Hoyme, H.E.8
White, S.M.9
Delatycki, M.B.10
Lampe, A.K.11
Clayton-Smith, J.12
-
57
-
-
0037374844
-
Diagnostic criteria, clinical characteristics, and natural history of Cohen syndrome
-
Chandler, K. E., Kidd, A., Al-Gazali, L., Kolehmainen, J., Lehesjoki, A. E., Black, G. C. and Clayton-Smith, J. (2003) Diagnostic criteria, clinical characteristics, and natural history of Cohen syndrome. J. Med. Genet. 40, 233-241.
-
(2003)
J. Med. Genet
, vol.40
, pp. 233-241
-
-
Chandler, K.E.1
Kidd, A.2
Al-Gazali, L.3
Kolehmainen, J.4
Lehesjoki, A.E.5
Black, G.C.6
Clayton-Smith, J.7
-
58
-
-
0038353767
-
Cohen syndrome is caused by mutations in a novel gene, COH1, encoding a transmembrane protein with a presumed role in vesicle-mediated sorting and intracellular protein transport
-
Kolehmainen, J., Black, G. C., Saarinen, A., Chandler, K., Clayton-Smith, J., Träskelin, A. L., Perveen, R., Kivitie-Kallio, S., Norio, R., Warburg, M., Fryns, J. P., de la Chapelle, A. et al. (2003) Cohen syndrome is caused by mutations in a novel gene, COH1, encoding a transmembrane protein with a presumed role in vesicle-mediated sorting and intracellular protein transport. Am. J. Hum. Genet. 72, 1359-1369.
-
(2003)
Am. J. Hum. Genet
, vol.72
, pp. 1359-1369
-
-
Kolehmainen, J.1
Black, G.C.2
Saarinen, A.3
Chandler, K.4
Clayton-Smith, J.5
Träskelin, A.L.6
Perveen, R.7
Kivitie-Kallio, S.8
Norio, R.9
Warburg, M.10
Fryns, J.P.11
de la Chapelle, A.12
-
59
-
-
0035653510
-
Genome-wide linkage analysis assessing parent-of-origin effects in the inheritance of type 2 diabetes and BMI in Pima Indians
-
Lindsay, R. S., Kobes, S., Knowler, W. C., Bennett, P. H. and Hanson, R. L. (2001) Genome-wide linkage analysis assessing parent-of-origin effects in the inheritance of type 2 diabetes and BMI in Pima Indians. Diabetes 50, 2850-2857.
-
(2001)
Diabetes
, vol.50
, pp. 2850-2857
-
-
Lindsay, R.S.1
Kobes, S.2
Knowler, W.C.3
Bennett, P.H.4
Hanson, R.L.5
-
60
-
-
0032231322
-
An autosomal genomic scan for loci linked to type II diabetes mellitus and body-mass index in Pima Indians
-
Hanson, R. L., Ehm, M. G., Pettitt, D. J., Prochazka, M., Thompson, D. B., Timberlake, D., Foroud, T., Kobes, S., Baier, L., Burns, D. K., Almasy, L., Blangero, J. et al. (1998) An autosomal genomic scan for loci linked to type II diabetes mellitus and body-mass index in Pima Indians. Am. J. Hum. Genet. 63, 1130-1138.
-
(1998)
Am. J. Hum. Genet
, vol.63
, pp. 1130-1138
-
-
Hanson, R.L.1
Ehm, M.G.2
Pettitt, D.J.3
Prochazka, M.4
Thompson, D.B.5
Timberlake, D.6
Foroud, T.7
Kobes, S.8
Baier, L.9
Burns, D.K.10
Almasy, L.11
Blangero, J.12
-
61
-
-
0842264056
-
Evidence of a novel quantitative-trait locus for obesity on chromosome 4p in Mexican Americans
-
Arya, R., Duggirala, R., Jenkinson, C. P., Almasy, L., Blangero, J., O'Connell, P. and Stern, M. P. (2004) Evidence of a novel quantitative-trait locus for obesity on chromosome 4p in Mexican Americans. Am. J. Hum. Genet. 74, 272-282.
-
(2004)
Am. J. Hum. Genet
, vol.74
, pp. 272-282
-
-
Arya, R.1
Duggirala, R.2
Jenkinson, C.P.3
Almasy, L.4
Blangero, J.5
O'Connell, P.6
Stern, M.P.7
-
62
-
-
19244362737
-
Quantitative variation in obesity-related traits and insulin precursors linked to the OB gene region on human chromosome 7
-
Duggirala, R., Stern, M. P., Mitchell, B. D., Reinhart, L. J., Shipman, P. A., Uresandi, O. C., Chung, W. K., Leibel, R. L., Hales, C. N., O'Connell, P. and Blangero, J. (1996) Quantitative variation in obesity-related traits and insulin precursors linked to the OB gene region on human chromosome 7. Am. J. Hum. Genet. 59, 694-703.
-
(1996)
Am. J. Hum. Genet
, vol.59
, pp. 694-703
-
-
Duggirala, R.1
Stern, M.P.2
Mitchell, B.D.3
Reinhart, L.J.4
Shipman, P.A.5
Uresandi, O.C.6
Chung, W.K.7
Leibel, R.L.8
Hales, C.N.9
O'Connell, P.10
Blangero, J.11
-
63
-
-
0032830999
-
A quantitative trait locus influencing BMI maps to the region of the beta-3 adrenergic receptor
-
Mitchell, B. D., Cole, S. A., Comuzzie, A. G., Almasy, L., Blangero, J., MacCluer, J. W. and Hixson, J. E. (1999) A quantitative trait locus influencing BMI maps to the region of the beta-3 adrenergic receptor. Diabetes 48, 1863-1867.
-
(1999)
Diabetes
, vol.48
, pp. 1863-1867
-
-
Mitchell, B.D.1
Cole, S.A.2
Comuzzie, A.G.3
Almasy, L.4
Blangero, J.5
MacCluer, J.W.6
Hixson, J.E.7
-
64
-
-
10744228132
-
-
Platte, P., Papanicolaou, G. J., Johnston, J., Klein, C. M., Doheny, K. F., Pugh, E. W., Roy-Gagnon, M. H., Stunkard, A. J., Francomano, C. A. and Wilson, A. F. (2003) A study of linkage and association of body mass index in the Old Order Amish. Am. J. Med. Genet. C. Semin. Med. Genet. 121, 71-80.
-
Platte, P., Papanicolaou, G. J., Johnston, J., Klein, C. M., Doheny, K. F., Pugh, E. W., Roy-Gagnon, M. H., Stunkard, A. J., Francomano, C. A. and Wilson, A. F. (2003) A study of linkage and association of body mass index in the Old Order Amish. Am. J. Med. Genet. C. Semin. Med. Genet. 121, 71-80.
-
-
-
-
65
-
-
17744383578
-
Genome-wide scan of obesity in the Old Order Amish
-
Hsueh, W. C., Mitchell, B. D., Schneider, J. L., St Jean, P. L., Pollin, T. I., Ehm, M. G., Wagner, M. J., Burns, D. K., Sakul, H., Bell, C. J. and Shuldiner, A. R. (2001) Genome-wide scan of obesity in the Old Order Amish. J. Clin. Endocrinol. Metab. 86, 1199-1205.
-
(2001)
J. Clin. Endocrinol. Metab
, vol.86
, pp. 1199-1205
-
-
Hsueh, W.C.1
Mitchell, B.D.2
Schneider, J.L.3
St Jean, P.L.4
Pollin, T.I.5
Ehm, M.G.6
Wagner, M.J.7
Burns, D.K.8
Sakul, H.9
Bell, C.J.10
Shuldiner, A.R.11
-
66
-
-
19944426878
-
-
Norris, J. M., Langefeld, C. D., Scherzinger, A. L., Rich, S. S., Bookman, E., Beck, S. R., Saad, M. F., Haffner, S. M., Bergman, R. N., Bowden, D. W. and Wagenknecht, L. E. (2005) Quantitative trait loci for abdominal fat and BMI in Hispanic-Americans and African-Americans: The IRAS Family study. Int. J. Obes. (Lond.) 29, 67-77.
-
Norris, J. M., Langefeld, C. D., Scherzinger, A. L., Rich, S. S., Bookman, E., Beck, S. R., Saad, M. F., Haffner, S. M., Bergman, R. N., Bowden, D. W. and Wagenknecht, L. E. (2005) Quantitative trait loci for abdominal fat and BMI in Hispanic-Americans and African-Americans: The IRAS Family study. Int. J. Obes. (Lond.) 29, 67-77.
-
-
-
-
67
-
-
0037407315
-
Linkage for BMI at 3q27 region confirmed in an African-American population
-
Luke, A., Wu, X., Zhu, X., Kan, D., Su, Y. and Cooper, R. (2003) Linkage for BMI at 3q27 region confirmed in an African-American population. Diabetes 52, 1284-1287.
-
(2003)
Diabetes
, vol.52
, pp. 1284-1287
-
-
Luke, A.1
Wu, X.2
Zhu, X.3
Kan, D.4
Su, Y.5
Cooper, R.6
-
68
-
-
3442898790
-
Whole genome scan for obstructive sleep apnea and obesity in African-American families
-
Palmer, L. J., Buxbaum, S. G., Larkin, E. K., Patel, S. R., Elston, R. C., Tishler, P. V. and Redline, S. (2004) Whole genome scan for obstructive sleep apnea and obesity in African-American families. Am. J. Respir. Crit. Care Med. 169, 1314-1321.
-
(2004)
Am. J. Respir. Crit. Care Med
, vol.169
, pp. 1314-1321
-
-
Palmer, L.J.1
Buxbaum, S.G.2
Larkin, E.K.3
Patel, S.R.4
Elston, R.C.5
Tishler, P.V.6
Redline, S.7
-
69
-
-
0036066280
-
A genome-wide scan for obesity in African-Americans
-
Zhu, X., Cooper, R. S., Luke, A., Chen, G., Wu, X., Kan, D., Chakravarti, A. and Weder, A. (2002) A genome-wide scan for obesity in African-Americans. Diabetes 51, 541-544.
-
(2002)
Diabetes
, vol.51
, pp. 541-544
-
-
Zhu, X.1
Cooper, R.S.2
Luke, A.3
Chen, G.4
Wu, X.5
Kan, D.6
Chakravarti, A.7
Weder, A.8
-
70
-
-
20144380431
-
-
Lewis, C. E., North, K. E., Arnett, D., Borecki, I. B., Coon, H., Ellison, R. C., Hunt, S. C., Oberman, A., Rich, S. S., Province, M. A. and Miller, M. B. (2005) Sex-specific findings from a genome-wide linkage analysis of human fatness in non-Hispanic whites and African Americans: The HyperGEN study. Int. J. Obes. (Lond.) 29, 639-649.
-
Lewis, C. E., North, K. E., Arnett, D., Borecki, I. B., Coon, H., Ellison, R. C., Hunt, S. C., Oberman, A., Rich, S. S., Province, M. A. and Miller, M. B. (2005) Sex-specific findings from a genome-wide linkage analysis of human fatness in non-Hispanic whites and African Americans: The HyperGEN study. Int. J. Obes. (Lond.) 29, 639-649.
-
-
-
-
71
-
-
0036260045
-
An X-chromosome scan reveals a locus for fat distribution in chromosome region Xp21-22
-
Price, R. A., Li, W. D. and Kilker, R. (2002) An X-chromosome scan reveals a locus for fat distribution in chromosome region Xp21-22. Diabetes 51, 1989-1991.
-
(2002)
Diabetes
, vol.51
, pp. 1989-1991
-
-
Price, R.A.1
Li, W.D.2
Kilker, R.3
-
72
-
-
0037219566
-
Interacting genetic loci on chromosomes 20 and 10 influence extreme human obesity
-
Dong, C., Wang, S., Li, W. D., Li, D., Zhao, H. and Price, R. A. (2003) Interacting genetic loci on chromosomes 20 and 10 influence extreme human obesity. Am. J. Hum. Genet. 72, 115-124.
-
(2003)
Am. J. Hum. Genet
, vol.72
, pp. 115-124
-
-
Dong, C.1
Wang, S.2
Li, W.D.3
Li, D.4
Zhao, H.5
Price, R.A.6
-
73
-
-
0036234398
-
A combined analysis of genomewide linkage scans for body mass index from the National Heart, Lung, and Blood Institute Family Blood Pressure Program
-
Wu, X., Cooper, R. S., Borecki, I., Hanis, C., Bray, M., Lewis, C. E., Zhu, X., Kan, D., Luke, A. and Curb, D. (2002) A combined analysis of genomewide linkage scans for body mass index from the National Heart, Lung, and Blood Institute Family Blood Pressure Program. Am. J. Hum. Genet. 70, 1247-1256.
-
(2002)
Am. J. Hum. Genet
, vol.70
, pp. 1247-1256
-
-
Wu, X.1
Cooper, R.S.2
Borecki, I.3
Hanis, C.4
Bray, M.5
Lewis, C.E.6
Zhu, X.7
Kan, D.8
Luke, A.9
Curb, D.10
-
74
-
-
18344374004
-
A genomewide linkage scan for quantitative-trait loci for obesity phenotypes
-
Deng, H. W., Deng, H., Liu, Y. J., Liu, Y. Z., Xu, F. H., Shen, H., Conway, T., Li, J. L., Huang, Q. Y., Davies, K. M. and Recker, R. R. (2002) A genomewide linkage scan for quantitative-trait loci for obesity phenotypes. Am. J. Hum. Genet. 70, 1138-1151.
-
(2002)
Am. J. Hum. Genet
, vol.70
, pp. 1138-1151
-
-
Deng, H.W.1
Deng, H.2
Liu, Y.J.3
Liu, Y.Z.4
Xu, F.H.5
Shen, H.6
Conway, T.7
Li, J.L.8
Huang, Q.Y.9
Davies, K.M.10
Recker, R.R.11
-
75
-
-
6444239276
-
Genetic dissection of human stature in a large sample of multiplex pedigrees
-
Liu, Y. Z., Xu, F. H., Shen, H., Liu, Y. J., Zhao, L. J., Long, J. R., Zhang, Y. Y., Xiao, P., Xiong, D. H., Dvornyk, V., Li, J. L., Conway, T. et al. (2004) Genetic dissection of human stature in a large sample of multiplex pedigrees. Ann. Hum. Genet. 68, 472-488.
-
(2004)
Ann. Hum. Genet
, vol.68
, pp. 472-488
-
-
Liu, Y.Z.1
Xu, F.H.2
Shen, H.3
Liu, Y.J.4
Zhao, L.J.5
Long, J.R.6
Zhang, Y.Y.7
Xiao, P.8
Xiong, D.H.9
Dvornyk, V.10
Li, J.L.11
Conway, T.12
-
76
-
-
84872239364
-
A genome-wide linkage scan for body mass index on Framingham Heart Study families
-
Moslehi, R., Goldstein, A. M., Beerman, M., Goldin, L. and Bergen, A. W. (2003) A genome-wide linkage scan for body mass index on Framingham Heart Study families. BMC Genet. 4 (Suppl. 1), S97.
-
(2003)
BMC Genet
, vol.4
, Issue.SUPPL. 1
-
-
Moslehi, R.1
Goldstein, A.M.2
Beerman, M.3
Goldin, L.4
Bergen, A.W.5
-
77
-
-
0037318997
-
A whole-genome scan for obstructive sleep apnea and obesity
-
Palmer, L. J., Buxbaum, S. G., Larkin, E., Patel, S. R., Elston, R. C., Tishler, P. V. and Redline, S. (2003) A whole-genome scan for obstructive sleep apnea and obesity. Am. J. Hum. Genet. 72, 340-350.
-
(2003)
Am. J. Hum. Genet
, vol.72
, pp. 340-350
-
-
Palmer, L.J.1
Buxbaum, S.G.2
Larkin, E.3
Patel, S.R.4
Elston, R.C.5
Tishler, P.V.6
Redline, S.7
-
78
-
-
10744229883
-
Linkage analysis of a composite factor for the multiple metabolic syndrome: The National Heart, Lung, and Blood Institute Family Heart Study
-
Tang, W., Miller, M. B., Rich, S. S., North, K. E., Pankow, J. S., Borecki, I. B., Myers, R. H., Hopkins, P. N., Leppert, M. and Arnett, D. K. (2003) Linkage analysis of a composite factor for the multiple metabolic syndrome: The National Heart, Lung, and Blood Institute Family Heart Study. Diabetes 52, 2840-2847.
-
(2003)
Diabetes
, vol.52
, pp. 2840-2847
-
-
Tang, W.1
Miller, M.B.2
Rich, S.S.3
North, K.E.4
Pankow, J.S.5
Borecki, I.B.6
Myers, R.H.7
Hopkins, P.N.8
Leppert, M.9
Arnett, D.K.10
-
79
-
-
14344273991
-
Quantitative trait loci on chromosomes 3 and 17 influence phenotypes of the metabolic syndrome
-
Kissebah, A. H., Sonnenberg, G. E., Myklebust, J., Goldstein, M., Broman, K., James, R. G., Marks, J. A., Krakower, G. R., Jacob, H. J., Weber, J., Martin, L., Blangero, J. et al. (2000) Quantitative trait loci on chromosomes 3 and 17 influence phenotypes of the metabolic syndrome. Proc. Natl. Acad. Sci. USA 97, 14478-14483.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 14478-14483
-
-
Kissebah, A.H.1
Sonnenberg, G.E.2
Myklebust, J.3
Goldstein, M.4
Broman, K.5
James, R.G.6
Marks, J.A.7
Krakower, G.R.8
Jacob, H.J.9
Weber, J.10
Martin, L.11
Blangero, J.12
-
80
-
-
13844253255
-
Possible genomic imprinting of three human obesity-related genetic loci
-
Dong, C., Li, W. D., Geller, F., Lei, L., Li, D., Gorlova, O. Y., Hebebrand, J., Amos, C. I., Nicholls, R. D. and Price, R. A. (2005) Possible genomic imprinting of three human obesity-related genetic loci. Am. J. Hum. Genet. 76, 427-437.
-
(2005)
Am. J. Hum. Genet
, vol.76
, pp. 427-437
-
-
Dong, C.1
Li, W.D.2
Geller, F.3
Lei, L.4
Li, D.5
Gorlova, O.Y.6
Hebebrand, J.7
Amos, C.I.8
Nicholls, R.D.9
Price, R.A.10
-
81
-
-
18344390035
-
A major predisposition locus for severe obesity, at 4p15-p14
-
Stone, S., Abkevich, V., Hunt, S. C., Gutin, A., Russell, D. L., Neff, C. D., Riley, R., Frech, G. C., Hensel, C. H., Jammulapati, S., Potter, J., Sexton, D. et al. (2002) A major predisposition locus for severe obesity, at 4p15-p14. Am. J. Hum. Genet. 70, 1459-1468.
-
(2002)
Am. J. Hum. Genet
, vol.70
, pp. 1459-1468
-
-
Stone, S.1
Abkevich, V.2
Hunt, S.C.3
Gutin, A.4
Russell, D.L.5
Neff, C.D.6
Riley, R.7
Frech, G.C.8
Hensel, C.H.9
Jammulapati, S.10
Potter, J.11
Sexton, D.12
-
82
-
-
33645489353
-
Genome scan for body mass index and height in the Framingham Heart Study
-
Geller, F., Dempfle, A. and Görg, T. (2003) Genome scan for body mass index and height in the Framingham Heart Study. BMC Genet. 4 (Suppl. 1), S91.
-
(2003)
BMC Genet
, vol.4
, Issue.SUPPL. 1
-
-
Geller, F.1
Dempfle, A.2
Görg, T.3
-
83
-
-
2342644820
-
Genomewide linkage to chromosome 6 for waist circumference in the Framingham Heart Study
-
Fox, C. S., Heard-Costa, N. L., Wilson, P. W., Levy, D., D'Agostino, R. B. Sr. and Atwood, L. D. (2004) Genomewide linkage to chromosome 6 for waist circumference in the Framingham Heart Study. Diabetes 53, 1399-1402.
-
(2004)
Diabetes
, vol.53
, pp. 1399-1402
-
-
Fox, C.S.1
Heard-Costa, N.L.2
Wilson, P.W.3
Levy, D.4
D'Agostino Sr., R.B.5
Atwood, L.D.6
-
84
-
-
0037645695
-
Linkage and linkage disequilibrium mapping of genes influencing human obesity in chromosome region 7q22.1-7q35
-
Li, W. D., Li, D., Wang, S., Zhang, S., Zhao, H. and Price, R. A. (2003) Linkage and linkage disequilibrium mapping of genes influencing human obesity in chromosome region 7q22.1-7q35. Diabetes 52, 1557-1561.
-
(2003)
Diabetes
, vol.52
, pp. 1557-1561
-
-
Li, W.D.1
Li, D.2
Wang, S.3
Zhang, S.4
Zhao, H.5
Price, R.A.6
-
85
-
-
0036139010
-
Quantitative-trait loci influencing body-mass index reside on chromosomes 7 and 13: The National Heart, Lung, and Blood Institute Family Heart Study
-
Feitosa, M. F., Borecki, I. B., Rich, S. S., Arnett, D. K., Sholinsky, P., Myers, R. H., Leppert, M. and Province, M. A. (2002) Quantitative-trait loci influencing body-mass index reside on chromosomes 7 and 13: The National Heart, Lung, and Blood Institute Family Heart Study. Am. J. Hum. Genet. 70, 72-82.
-
(2002)
Am. J. Hum. Genet
, vol.70
, pp. 72-82
-
-
Feitosa, M.F.1
Borecki, I.B.2
Rich, S.S.3
Arnett, D.K.4
Sholinsky, P.5
Myers, R.H.6
Leppert, M.7
Province, M.A.8
-
86
-
-
1442349994
-
An obesity-related locus in chromosome region 12q23-24
-
Li, W. D., Dong, C., Li, D., Zhao, H. and Price, R. A. (2004) An obesity-related locus in chromosome region 12q23-24. Diabetes 53, 812-820.
-
(2004)
Diabetes
, vol.53
, pp. 812-820
-
-
Li, W.D.1
Dong, C.2
Li, D.3
Zhao, H.4
Price, R.A.5
-
87
-
-
0038040484
-
Genetic linkage and imprinting effects on body mass index in children and young adults
-
Gorlova, O. Y., Amos, C. I., Wang, N. W., Shete, S., Turner, S. T. and Boerwinkle, E. (2003) Genetic linkage and imprinting effects on body mass index in children and young adults. Eur. J. Hum. Genet. 11, 425-432.
-
(2003)
Eur. J. Hum. Genet
, vol.11
, pp. 425-432
-
-
Gorlova, O.Y.1
Amos, C.I.2
Wang, N.W.3
Shete, S.4
Turner, S.T.5
Boerwinkle, E.6
-
88
-
-
0034815419
-
Linkage of body mass index to chromosome 20 in Utah pedigrees
-
Hunt, S. C., Abkevich, V., Hensel, C. H., Gutin, A., Neff, C. D., Russell, D. L., Tran, T., Hong, X., Jammulapati, S., Riley, R., Weaver-Feldhaus, J., Macalma, T. et al. (2001) Linkage of body mass index to chromosome 20 in Utah pedigrees. Hum. Genet. 109, 279-285.
-
(2001)
Hum. Genet
, vol.109
, pp. 279-285
-
-
Hunt, S.C.1
Abkevich, V.2
Hensel, C.H.3
Gutin, A.4
Neff, C.D.5
Russell, D.L.6
Tran, T.7
Hong, X.8
Jammulapati, S.9
Riley, R.10
Weaver-Feldhaus, J.11
Macalma, T.12
-
89
-
-
0033364313
-
Genome scan for human obesity and linkage to markers in 20q13
-
Lee, J. H., Reed, D. R., Li, W. D., Xu, W., Joo, E. J., Kilker, R. L., Nanthakumar, E., North, M., Sakul, H., Bell, C. and Price, R. A. (1999) Genome scan for human obesity and linkage to markers in 20q13. Am. J. Hum. Genet. 64, 196-209.
-
(1999)
Am. J. Hum. Genet
, vol.64
, pp. 196-209
-
-
Lee, J.H.1
Reed, D.R.2
Li, W.D.3
Xu, W.4
Joo, E.J.5
Kilker, R.L.6
Nanthakumar, E.7
North, M.8
Sakul, H.9
Bell, C.10
Price, R.A.11
-
90
-
-
0000082145
-
An exploratory investigation of genetic linkage with body composition and fatness phenotypes: The Quebec Family Study
-
Borecki, I. B., Rice, T., Perusse, L., Bouchard, C. and Rao, D. C. (1994) An exploratory investigation of genetic linkage with body composition and fatness phenotypes: The Quebec Family Study. Obes. Res. 2, 213-219.
-
(1994)
Obes. Res
, vol.2
, pp. 213-219
-
-
Borecki, I.B.1
Rice, T.2
Perusse, L.3
Bouchard, C.4
Rao, D.C.5
-
91
-
-
1442349990
-
A genome-wide scan for childhood obesity-associated traits in French families shows significant linkage on chromosome 6q22.31-q23.2
-
Meyre, D., Lecoeur, C., Delplanque, J., Francke, S., Vatin, V., Durand, E., Weill, J., Dina, C. and Froguel, P. (2004) A genome-wide scan for childhood obesity-associated traits in French families shows significant linkage on chromosome 6q22.31-q23.2. Diabetes 53, 803-811.
-
(2004)
Diabetes
, vol.53
, pp. 803-811
-
-
Meyre, D.1
Lecoeur, C.2
Delplanque, J.3
Francke, S.4
Vatin, V.5
Durand, E.6
Weill, J.7
Dina, C.8
Froguel, P.9
-
92
-
-
3042742243
-
Genome-wide linkage analysis for severe obesity in French Caucasians finds significant susceptibility locus on chromosome 19q
-
Bell, C. G., Benzinou, M., Siddiq, A., Lecoeur, C., Dina, C., Lemainque, A., Clément, K., Basdevant, A., Guy-Grand, B., Mein, C. A., Meyre, D. and Froguel, P. (2004) Genome-wide linkage analysis for severe obesity in French Caucasians finds significant susceptibility locus on chromosome 19q. Diabetes 53, 1857-1865.
-
(2004)
Diabetes
, vol.53
, pp. 1857-1865
-
-
Bell, C.G.1
Benzinou, M.2
Siddiq, A.3
Lecoeur, C.4
Dina, C.5
Lemainque, A.6
Clément, K.7
Basdevant, A.8
Guy-Grand, B.9
Mein, C.A.10
Meyre, D.11
Froguel, P.12
-
93
-
-
17344371519
-
Agenome-wide scan for human obesity genes reveals a major susceptibility locus on chromosome 10
-
Hager, J., Dina, C., Francke, S., Dubois, S., Houari, M., Vatin, V., Vaillant, E., Lorentz, N., Basdevant, A., Clément, K., Guy-Grand, B. and Froguel, P. (1998)Agenome-wide scan for human obesity genes reveals a major susceptibility locus on chromosome 10. Nat. Genet. 20, 304-308.
-
(1998)
Nat. Genet
, vol.20
, pp. 304-308
-
-
Hager, J.1
Dina, C.2
Francke, S.3
Dubois, S.4
Houari, M.5
Vatin, V.6
Vaillant, E.7
Lorentz, N.8
Basdevant, A.9
Clément, K.10
Guy-Grand, B.11
Froguel, P.12
-
94
-
-
1842292786
-
Identification of an obesity quantitative trait locus on mouse chromosome 2 and evidence of linkage to body fat and insulin on the human homologous region 20q
-
Lembertas, A. V., Pérusse, L., Chagnon, Y. C., Fisler, J. S., Warden, C. H., Purcell-Huynh, D. A., Dionne, F. T., Gagnon, J., Nadeau, A., Lusis, A. J. and Bouchard, C. (1997) Identification of an obesity quantitative trait locus on mouse chromosome 2 and evidence of linkage to body fat and insulin on the human homologous region 20q. J. Clin. Invest. 100, 1240-1247.
-
(1997)
J. Clin. Invest
, vol.100
, pp. 1240-1247
-
-
Lembertas, A.V.1
Pérusse, L.2
Chagnon, Y.C.3
Fisler, J.S.4
Warden, C.H.5
Purcell-Huynh, D.A.6
Dionne, F.T.7
Gagnon, J.8
Nadeau, A.9
Lusis, A.J.10
Bouchard, C.11
-
95
-
-
0033694150
-
Genome-wide scan of obesity in Finnish sibpairs reveals linkage to chromosome Xq24
-
Ohman, M., Oksanen, L., Kaprio, J., Koskenvuo, M., Mustajoki, P., Rissanen, A., Salmi, J., Kontula, K. and Peltonen, L. (2000) Genome-wide scan of obesity in Finnish sibpairs reveals linkage to chromosome Xq24. J. Clin. Endocrinol. Metab. 85, 3183-3190.
-
(2000)
J. Clin. Endocrinol. Metab
, vol.85
, pp. 3183-3190
-
-
Ohman, M.1
Oksanen, L.2
Kaprio, J.3
Koskenvuo, M.4
Mustajoki, P.5
Rissanen, A.6
Salmi, J.7
Kontula, K.8
Peltonen, L.9
-
96
-
-
0033758721
-
The Finland-United States investigation of non-insulin-dependent diabetes mellitus genetics (FUSION) study. II. An autosomal genome scan for diabetes-related quantitative-trait loci
-
Watanabe, R. M., Ghosh, S., Langefeld, C. D., Valle, T. T., Hauser, E. R., Magnuson, V. L., Mohlke, K. L., Silander, K., Ally, D. S., Chines, P., Blaschak-Harvan, J., Douglas, J. A. et al. (2000) The Finland-United States investigation of non-insulin-dependent diabetes mellitus genetics (FUSION) study. II. An autosomal genome scan for diabetes-related quantitative-trait loci. Am. J. Hum. Genet. 67, 1186-1200.
-
(2000)
Am. J. Hum. Genet
, vol.67
, pp. 1186-1200
-
-
Watanabe, R.M.1
Ghosh, S.2
Langefeld, C.D.3
Valle, T.T.4
Hauser, E.R.5
Magnuson, V.L.6
Mohlke, K.L.7
Silander, K.8
Ally, D.S.9
Chines, P.10
Blaschak-Harvan, J.11
Douglas, J.A.12
-
97
-
-
0037313906
-
Genome scan for childhood and adolescent obesity in German families
-
Saar, K., Geller, F., Rüschendorf, F., Reis, A., Friedel, S., Schäuble, N., Nürnberg, P., Siegfried, W., Goldschmidt, H. P., Schäfer, H., Ziegler, A., Remschmidt, H., Hinney, A. and Hebebrand, J. (2003) Genome scan for childhood and adolescent obesity in German families. Pediatrics 111, 321-327.
-
(2003)
Pediatrics
, vol.111
, pp. 321-327
-
-
Saar, K.1
Geller, F.2
Rüschendorf, F.3
Reis, A.4
Friedel, S.5
Schäuble, N.6
Nürnberg, P.7
Siegfried, W.8
Goldschmidt, H.P.9
Schäfer, H.10
Ziegler, A.11
Remschmidt, H.12
Hinney, A.13
Hebebrand, J.14
-
98
-
-
17744395716
-
Independent confirmation of a major locus for obesity on chromosome 10
-
Hinney, A., Ziegler, A., Oeffner, F., Wedewardt, C., Vogel, M., Wulftange, H., Geller, F., Stübing, K., Siegfried, W., Goldschmidt, H. P., Remschmidt, H. and Hebebrand, J. (2000) Independent confirmation of a major locus for obesity on chromosome 10. J. Clin. Endocrinol. Metab. 85, 2962-2965.
-
(2000)
J. Clin. Endocrinol. Metab
, vol.85
, pp. 2962-2965
-
-
Hinney, A.1
Ziegler, A.2
Oeffner, F.3
Wedewardt, C.4
Vogel, M.5
Wulftange, H.6
Geller, F.7
Stübing, K.8
Siegfried, W.9
Goldschmidt, H.P.10
Remschmidt, H.11
Hebebrand, J.12
-
99
-
-
1942499472
-
Further evidence for a QTL influencing body mass index on chromosome 7p from a genome-wide scan in Dutch families
-
Heijmans, B. T., Beem, A. L., Willemsen, G., Posthuma, D., Slagboom, P. E. and Boomsma, D. (2004) Further evidence for a QTL influencing body mass index on chromosome 7p from a genome-wide scan in Dutch families. Twin Res. 7, 192-196.
-
(2004)
Twin Res
, vol.7
, pp. 192-196
-
-
Heijmans, B.T.1
Beem, A.L.2
Willemsen, G.3
Posthuma, D.4
Slagboom, P.E.5
Boomsma, D.6
-
100
-
-
0033757442
-
Genome scan for adiposity in Dutch dyslipidemic families reveals novel quantitative trait loci for leptin, body mass index and soluble tumor necrosis factor receptor superfamily 1A
-
van der Kallen, C. J., Cantor, R. M., van Greevenbroek, M. M., Geurts, J. M., Bouwman, F. G., Aouizerat, B. E., Allayee, H., Buurman, W. A., Lusis, A. J., Rotter, J. I. and de Bruin, T. W. (2000) Genome scan for adiposity in Dutch dyslipidemic families reveals novel quantitative trait loci for leptin, body mass index and soluble tumor necrosis factor receptor superfamily 1A. Int. J. Obes. Relat. Metab. Disord. 24, 1381-1391.
-
(2000)
Int. J. Obes. Relat. Metab. Disord
, vol.24
, pp. 1381-1391
-
-
van der Kallen, C.J.1
Cantor, R.M.2
van Greevenbroek, M.M.3
Geurts, J.M.4
Bouwman, F.G.5
Aouizerat, B.E.6
Allayee, H.7
Buurman, W.A.8
Lusis, A.J.9
Rotter, J.I.10
de Bruin, T.W.11
-
101
-
-
0042730267
-
A genome-wide scan for body mass index among Nigerian families
-
Adeyemo, A., Luke, A., Cooper, R., Wu, X., Tayo, B., Zhu, X., Rotimi, C., Bouzekri, N. and Ward, R. (2003) A genome-wide scan for body mass index among Nigerian families. Obes. Res. 11, 266-273.
-
(2003)
Obes. Res
, vol.11
, pp. 266-273
-
-
Adeyemo, A.1
Luke, A.2
Cooper, R.3
Wu, X.4
Tayo, B.5
Zhu, X.6
Rotimi, C.7
Bouzekri, N.8
Ward, R.9
-
102
-
-
4644227228
-
Genome-wide scan for metabolic syndrome and related quantitative traits in Hong Kong Chinese and confirmation of a susceptibility locus on chromosome 1q21-q25
-
Ng, M. C., So, W. Y., Lam, V. K., Cockram, C. S., Bell, G. I., Cox, N. J. and Chan, J. C. (2004) Genome-wide scan for metabolic syndrome and related quantitative traits in Hong Kong Chinese and confirmation of a susceptibility locus on chromosome 1q21-q25. Diabetes 53, 2676-2683.
-
(2004)
Diabetes
, vol.53
, pp. 2676-2683
-
-
Ng, M.C.1
So, W.Y.2
Lam, V.K.3
Cockram, C.S.4
Bell, G.I.5
Cox, N.J.6
Chan, J.C.7
-
103
-
-
0029741063
-
The future of genetic studies of complex human diseases
-
Risch, N. and Merikangas, K. (1996) The future of genetic studies of complex human diseases. Science 273, 1516-1517.
-
(1996)
Science
, vol.273
, pp. 1516-1517
-
-
Risch, N.1
Merikangas, K.2
-
104
-
-
0032189782
-
Obesity associated with a mutation in a genetic regulator of adipocyte differentiation
-
Ristow, M., Müller-Wieland, D., Pfeiffer, A., Krone, W. and Kahn, C. R. (1998) Obesity associated with a mutation in a genetic regulator of adipocyte differentiation. N. Engl. J. Med. 339, 953-959.
-
(1998)
N. Engl. J. Med
, vol.339
, pp. 953-959
-
-
Ristow, M.1
Müller-Wieland, D.2
Pfeiffer, A.3
Krone, W.4
Kahn, C.R.5
-
105
-
-
0031595923
-
A Pro12Ala substitution in PPARgamma2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity
-
Deeb, S. S., Fajas, L., Nemoto, M., Pihlajamäki, J., Mykkänen, L., Kuusisto, J., Laakso, M., Fujimoto, W. and Auwerx, J. (1998) A Pro12Ala substitution in PPARgamma2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity. Nat. Genet. 20, 284-287.
-
(1998)
Nat. Genet
, vol.20
, pp. 284-287
-
-
Deeb, S.S.1
Fajas, L.2
Nemoto, M.3
Pihlajamäki, J.4
Mykkänen, L.5
Kuusisto, J.6
Laakso, M.7
Fujimoto, W.8
Auwerx, J.9
-
106
-
-
0035215987
-
The effect of the Gly16Arg polymorphism of the beta(2)-adrenergic receptor gene on plasma free fatty acid levels is modulated by physical activity
-
Meirhaeghe, A., Luan, J., Selberg-Franks, P., Hennings, S., Mitchell, J., Halsall, D., O'Rahilly, S. and Wareham, N. J. (2001) The effect of the Gly16Arg polymorphism of the beta(2)-adrenergic receptor gene on plasma free fatty acid levels is modulated by physical activity. J. Clin. Endocrinol. Metab. 86, 5881-5887.
-
(2001)
J. Clin. Endocrinol. Metab
, vol.86
, pp. 5881-5887
-
-
Meirhaeghe, A.1
Luan, J.2
Selberg-Franks, P.3
Hennings, S.4
Mitchell, J.5
Halsall, D.6
O'Rahilly, S.7
Wareham, N.J.8
-
107
-
-
21544454653
-
Beta2- and beta3-adrenergic receptor polymorphisms are related to the onset of weight gain and blood pressure elevation over 5 years
-
Masuo, K., Katsuya, T., Fu, Y., Rakugi, H., Ogihara, T. and Tuck, M. L. (2005) Beta2- and beta3-adrenergic receptor polymorphisms are related to the onset of weight gain and blood pressure elevation over 5 years. Circulation 111, 3429-3434.
-
(2005)
Circulation
, vol.111
, pp. 3429-3434
-
-
Masuo, K.1
Katsuya, T.2
Fu, Y.3
Rakugi, H.4
Ogihara, T.5
Tuck, M.L.6
-
108
-
-
0036525939
-
The 27Glu polymorphism of the beta2-adrenergic receptor gene interacts with physical activity influencing obesity risk among female subjects
-
Corbalán, M. S., Marti, A., Forga, L., Martínez- González, M. A. and Martínez, J. A. (2002) The 27Glu polymorphism of the beta2-adrenergic receptor gene interacts with physical activity influencing obesity risk among female subjects. Clin. Genet. 61, 305-307.
-
(2002)
Clin. Genet
, vol.61
, pp. 305-307
-
-
Corbalán, M.S.1
Marti, A.2
Forga, L.3
Martínez- González, M.A.4
Martínez, J.A.5
-
109
-
-
0028978910
-
Genetic variation in the beta 3-adrenergic receptor and an increased capacity to gain weight in patients with morbid obesity
-
Clément, K., Vaisse, C., Manning, B. S., Basdevant, A., Guy-Grand, B., Ruiz, J., Silver, K. D., Shuldiner, A. R., Froguel, P. and Strosberg, A. D. (1995) Genetic variation in the beta 3-adrenergic receptor and an increased capacity to gain weight in patients with morbid obesity. N. Engl. J. Med. 333, 352-354.
-
(1995)
N. Engl. J. Med
, vol.333
, pp. 352-354
-
-
Clément, K.1
Vaisse, C.2
Manning, B.S.3
Basdevant, A.4
Guy-Grand, B.5
Ruiz, J.6
Silver, K.D.7
Shuldiner, A.R.8
Froguel, P.9
Strosberg, A.D.10
-
110
-
-
0032004989
-
A paired sibling analysis of the beta-3 adrenergic receptor and obesity in Mexican Americans
-
Mitchell, B. D., Blangero, J., Comuzzie, A. G., Almasy, L. A., Shuldiner, A. R., Silver, K., Stern, M. P., MacCluer, J. W. and Hixson, J. E. (1998) A paired sibling analysis of the beta-3 adrenergic receptor and obesity in Mexican Americans. J. Clin. Invest. 101, 584-587.
-
(1998)
J. Clin. Invest
, vol.101
, pp. 584-587
-
-
Mitchell, B.D.1
Blangero, J.2
Comuzzie, A.G.3
Almasy, L.A.4
Shuldiner, A.R.5
Silver, K.6
Stern, M.P.7
MacCluer, J.W.8
Hixson, J.E.9
-
111
-
-
0029658675
-
The Trp64Arg mutation of the beta3 adrenergic receptor gene has no effect on obesity phenotypes in the Québec Family Study and Swedish Obese Subjects cohorts
-
Gagnon, J., Maurige, P., Roy, S., Sjöström, D., Chagnon, Y. C., Dionne, F. T., Oppert, J. M., Pérusse, L., Sjöström, L. and Bouchard, C. (1996) The Trp64Arg mutation of the beta3 adrenergic receptor gene has no effect on obesity phenotypes in the Québec Family Study and Swedish Obese Subjects cohorts. J. Clin. Invest. 98, 2086-2093.
-
(1996)
J. Clin. Invest
, vol.98
, pp. 2086-2093
-
-
Gagnon, J.1
Maurige, P.2
Roy, S.3
Sjöström, D.4
Chagnon, Y.C.5
Dionne, F.T.6
Oppert, J.M.7
Pérusse, L.8
Sjöström, L.9
Bouchard, C.10
-
112
-
-
0346101834
-
The Trp(64)Arg polymorphism of the beta(3)-adrenergic receptor gene is not associated with body weight or body mass index in Japanese: A longitudinal analysis
-
Matsushita, Y., Yokoyama, T., Yoshiike, N., Matsumura, Y., Date, C., Kawahara, K. and Tanaka, H. (2003) The Trp(64)Arg polymorphism of the beta(3)-adrenergic receptor gene is not associated with body weight or body mass index in Japanese: A longitudinal analysis. J. Clin. Endocrinol. Metab. 88, 5914-5920.
-
(2003)
J. Clin. Endocrinol. Metab
, vol.88
, pp. 5914-5920
-
-
Matsushita, Y.1
Yokoyama, T.2
Yoshiike, N.3
Matsumura, Y.4
Date, C.5
Kawahara, K.6
Tanaka, H.7
-
113
-
-
0029843407
-
Additive effect of A→G (-3826) variant of the uncoupling protein gene and the Trp64Arg mutation of the beta 3-adrenergic receptor gene on weight gain in morbid obesity
-
Clément, K., Ruiz, J., Cassard-Doulcier, A. M., Bouillaud, F., Ricquier, D., Basdevant, A., Guy-Grand, B. and Froguel, P. (1996) Additive effect of A→G (-3826) variant of the uncoupling protein gene and the Trp64Arg mutation of the beta 3-adrenergic receptor gene on weight gain in morbid obesity. Int. J. Obes. Relat. Metab. Disord. 20, 1062-1066.
-
(1996)
Int. J. Obes. Relat. Metab. Disord
, vol.20
, pp. 1062-1066
-
-
Clément, K.1
Ruiz, J.2
Cassard-Doulcier, A.M.3
Bouillaud, F.4
Ricquier, D.5
Basdevant, A.6
Guy-Grand, B.7
Froguel, P.8
-
114
-
-
0346101854
-
The-3826 A→G variant of the uncoupling protein-1 gene diminishes postprandial thermogenesis after a high fat meal in healthy boys
-
Nagai, N., Sakane, N., Ueno, L. M., Hamada, T. and Moritani, T. (2003) The-3826 A→G variant of the uncoupling protein-1 gene diminishes postprandial thermogenesis after a high fat meal in healthy boys. J. Clin. Endocrinol. Metab. 88, 5661-5667.
-
(2003)
J. Clin. Endocrinol. Metab
, vol.88
, pp. 5661-5667
-
-
Nagai, N.1
Sakane, N.2
Ueno, L.M.3
Hamada, T.4
Moritani, T.5
-
115
-
-
0034972150
-
A common polymorphism in the promoter of UCP2 is associated with decreased risk of obesity in middle-aged humans
-
Esterbauer, H., Schneitler, C., Oberkofler, H., Ebenbichler, C., Paulweber, B., Sandhofer, F., Ladurner, G., Hell, E., Strosberg, A. D., Patsch, J. R., Krempler, F. and Patsch, W. (2001) A common polymorphism in the promoter of UCP2 is associated with decreased risk of obesity in middle-aged humans. Nat. Genet. 28, 178-183.
-
(2001)
Nat. Genet
, vol.28
, pp. 178-183
-
-
Esterbauer, H.1
Schneitler, C.2
Oberkofler, H.3
Ebenbichler, C.4
Paulweber, B.5
Sandhofer, F.6
Ladurner, G.7
Hell, E.8
Strosberg, A.D.9
Patsch, J.R.10
Krempler, F.11
Patsch, W.12
-
116
-
-
0034003721
-
Agenetic variation in the 5′ flanking region of the UCP3 gene is associated with body mass index in humans in interaction with physical activity
-
Otabe, S., Clement, K., Dina, C., Pelloux, V., Guy-Grand, B., Froguel, P. and Vasseur, F. (2000)Agenetic variation in the 5′ flanking region of the UCP3 gene is associated with body mass index in humans in interaction with physical activity. Diabetologia 43, 245-249.
-
(2000)
Diabetologia
, vol.43
, pp. 245-249
-
-
Otabe, S.1
Clement, K.2
Dina, C.3
Pelloux, V.4
Guy-Grand, B.5
Froguel, P.6
Vasseur, F.7
-
117
-
-
0035016780
-
G-308A polymorphism of the tumor necrosis factor alpha gene promoter and salivary cortisol secretion
-
Rosmond, R., Chagnon, M., Bouchard, C. and Björntorp, P. (2001) G-308A polymorphism of the tumor necrosis factor alpha gene promoter and salivary cortisol secretion. J. Clin. Endocrinol. Metab. 86, 2178-2180.
-
(2001)
J. Clin. Endocrinol. Metab
, vol.86
, pp. 2178-2180
-
-
Rosmond, R.1
Chagnon, M.2
Bouchard, C.3
Björntorp, P.4
-
118
-
-
23344440637
-
Angiotensin-converting enzyme insertion/deletion genotype, exercise, and physical decline
-
Kritchevsky, S. B., Nicklas, B. J., Visser, M., Simonsick, E. M., Newman, A. B., Harris, T. B., Lange, E. M., Penninx, B. X., Goodpaster, B. H., Satterfield, S., Colbert, L. H., Rubin, S. M. and Pahor, M. (2005) Angiotensin-converting enzyme insertion/deletion genotype, exercise, and physical decline. JAMA 294, 691-698.
-
(2005)
JAMA
, vol.294
, pp. 691-698
-
-
Kritchevsky, S.B.1
Nicklas, B.J.2
Visser, M.3
Simonsick, E.M.4
Newman, A.B.5
Harris, T.B.6
Lange, E.M.7
Penninx, B.X.8
Goodpaster, B.H.9
Satterfield, S.10
Colbert, L.H.11
Rubin, S.M.12
Pahor, M.13
-
119
-
-
39049177166
-
Genetic factors for obesity
-
Yamada, Y., Kato, K., Kameyama, T., Yokoi, K., Matsuo, H., Segawa, T., Watanabe, S., Ichihara, S., Yoshida, H., Satoh, K. and Nozawa, Y. (2006) Genetic factors for obesity. Int. J. Mol. Med. 18, 843-851.
-
(2006)
Int. J. Mol. Med
, vol.18
, pp. 843-851
-
-
Yamada, Y.1
Kato, K.2
Kameyama, T.3
Yokoi, K.4
Matsuo, H.5
Segawa, T.6
Watanabe, S.7
Ichihara, S.8
Yoshida, H.9
Satoh, K.10
Nozawa, Y.11
-
120
-
-
0032794634
-
Worldwide ethnic distribution of the G protein beta3 subunit 825T allele and its association with obesity in Caucasian, Chinese, and Black African individuals
-
Siffert, W., Forster, P., Jöckel, K. H., Mvere, D. A., Brinkmann, B., Naber, C., Crookes, R., Du, P. H. A., Epplen, J. T., Fridey, J., Freedman, B. I., Müller, N. et al. (1999)Worldwide ethnic distribution of the G protein beta3 subunit 825T allele and its association with obesity in Caucasian, Chinese, and Black African individuals. J. Am. Soc. Nephrol. 10, 1921-1930.
-
(1999)
J. Am. Soc. Nephrol
, vol.10
, pp. 1921-1930
-
-
Siffert, W.1
Forster, P.2
Jöckel, K.H.3
Mvere, D.A.4
Brinkmann, B.5
Naber, C.6
Crookes, R.7
Du, P.H.A.8
Epplen, J.T.9
Fridey, J.10
Freedman, B.I.11
Müller, N.12
-
121
-
-
0034620791
-
G protein beta3 subunit 825 TT genotype and post-pregnancy weight retention
-
Gutersohn, A., Naber, C., Müller, N., Erbel, R. and Siffert, W. (2000) G protein beta3 subunit 825 TT genotype and post-pregnancy weight retention. Lancet 355, 1240-1241.
-
(2000)
Lancet
, vol.355
, pp. 1240-1241
-
-
Gutersohn, A.1
Naber, C.2
Müller, N.3
Erbel, R.4
Siffert, W.5
-
122
-
-
0034621062
-
Association of maternal G protein beta3 subunit 825T allele with low birth weight
-
Hocher, B., Slowinski, T., Stolze, T., Pleschka, A., Neumayer, H. H. and Halle, H. (2000) Association of maternal G protein beta3 subunit 825T allele with low birth weight. Lancet 355, 1241-1242.
-
(2000)
Lancet
, vol.355
, pp. 1241-1242
-
-
Hocher, B.1
Slowinski, T.2
Stolze, T.3
Pleschka, A.4
Neumayer, H.H.5
Halle, H.6
-
123
-
-
0034527931
-
Association of the G-2548A polymorphism in the 5′ region of the LEP gene with overweight
-
Mammès, O., Betoulle, D., Aubert, R., Herbeth, B., Siest, G. and Fumeron, F. (2000) Association of the G-2548A polymorphism in the 5′ region of the LEP gene with overweight. Ann. Hum. Genet. 64, 391-394.
-
(2000)
Ann. Hum. Genet
, vol.64
, pp. 391-394
-
-
Mammès, O.1
Betoulle, D.2
Aubert, R.3
Herbeth, B.4
Siest, G.5
Fumeron, F.6
-
124
-
-
2342609965
-
Apolymorphism in the 5′ untranslated region of the human ob gene is associated with low leptin levels
-
Hager, J., Clement, K., Francke, S., Dina, C., Raison, J., Lahlou, N., Rich, N., Pelloux, V., Basdevant, A., Guy-Grand, B., North, M. and Froguel, P. (1998)Apolymorphism in the 5′ untranslated region of the human ob gene is associated with low leptin levels. Int. J. Obes. Relat. Metab. Disord. 22, 200-205.
-
(1998)
Int. J. Obes. Relat. Metab. Disord
, vol.22
, pp. 200-205
-
-
Hager, J.1
Clement, K.2
Francke, S.3
Dina, C.4
Raison, J.5
Lahlou, N.6
Rich, N.7
Pelloux, V.8
Basdevant, A.9
Guy-Grand, B.10
North, M.11
Froguel, P.12
-
125
-
-
0032871802
-
Sequence variants in the 5′ flanking region of the leptin gene are associated with obesity in women
-
Li, W. D., Reed, D. R., Lee, J. H., Xu, W., Kilker, R. L., Sodam, B. R. and Price, R. A. (1999) Sequence variants in the 5′ flanking region of the leptin gene are associated with obesity in women. Ann. Hum. Genet. 63, 227-234.
-
(1999)
Ann. Hum. Genet
, vol.63
, pp. 227-234
-
-
Li, W.D.1
Reed, D.R.2
Lee, J.H.3
Xu, W.4
Kilker, R.L.5
Sodam, B.R.6
Price, R.A.7
-
126
-
-
0035073893
-
A single nucleotide polymorphism (SNP) in the leptin receptor is associated with BMI, fat mass and leptin levels in postmenopausal Caucasian women
-
Quinton, N. D., Lee, A. J., Ross, R. J., Eastell, R. and Blakemore, A. I. (2001) A single nucleotide polymorphism (SNP) in the leptin receptor is associated with BMI, fat mass and leptin levels in postmenopausal Caucasian women. Hum. Genet. 108, 233-236.
-
(2001)
Hum. Genet
, vol.108
, pp. 233-236
-
-
Quinton, N.D.1
Lee, A.J.2
Ross, R.J.3
Eastell, R.4
Blakemore, A.I.5
-
127
-
-
0034917636
-
Leptin receptor gene polymorphisms are associated with insulin in obese women with impaired glucose tolerance
-
Wauters, M., Mertens, I., Rankinen, T., Chagnon, M., Bouchard, C. and Van Gaal, L. (2001) Leptin receptor gene polymorphisms are associated with insulin in obese women with impaired glucose tolerance. J. Clin. Endocrinol. Metab. 86, 3227-3232.
-
(2001)
J. Clin. Endocrinol. Metab
, vol.86
, pp. 3227-3232
-
-
Wauters, M.1
Mertens, I.2
Rankinen, T.3
Chagnon, M.4
Bouchard, C.5
Van Gaal, L.6
-
128
-
-
33748465942
-
Leptin receptor Lys656Asn polymorphism is associated with decreased leptin response and weight loss secondary to a lifestyle modification in obese patients
-
de Luis Roman, D., de la Fuente, R. A., Sagrado, M. G., Izaola, O. and Vicente, R. C. (2006) Leptin receptor Lys656Asn polymorphism is associated with decreased leptin response and weight loss secondary to a lifestyle modification in obese patients. Arch. Med. Res. 37, 854-859.
-
(2006)
Arch. Med. Res
, vol.37
, pp. 854-859
-
-
de Luis Roman, D.1
de la Fuente, R.A.2
Sagrado, M.G.3
Izaola, O.4
Vicente, R.C.5
-
129
-
-
0347354997
-
The SLC6A14 gene shows evidence of association with obesity
-
Suviolahti, E., Oksanen, L. J., Ohman, M., Cantor, R. M., Ridderstrale, M., Tuomi, T., Kaprio, J., Rissanen, A., Mustajoki, P., Jousilahti, P., Vartiainen, E., Silander, K. et al. (2003) The SLC6A14 gene shows evidence of association with obesity. J. Clin. Invest. 112, 1762-1772.
-
(2003)
J. Clin. Invest
, vol.112
, pp. 1762-1772
-
-
Suviolahti, E.1
Oksanen, L.J.2
Ohman, M.3
Cantor, R.M.4
Ridderstrale, M.5
Tuomi, T.6
Kaprio, J.7
Rissanen, A.8
Mustajoki, P.9
Jousilahti, P.10
Vartiainen, E.11
Silander, K.12
-
130
-
-
2642512097
-
GAD2on chromosome 10p12 is a candidate gene for human obesity
-
Boutin, P., Dina, C., Vasseur, F., Dubois, S., Corset, L., Séron, K., Bekris, L., Cabellon, J., Neve, B., Vasseur-Delannoy, V., Chikri, M., Charles, M. A., Clement, K., Lernmark, A. and Froguel, P. (2003)GAD2on
-
(2003)
PLoS Biol
, vol.1
-
-
Boutin, P.1
Dina, C.2
Vasseur, F.3
Dubois, S.4
Corset, L.5
Séron, K.6
Bekris, L.7
Cabellon, J.8
Neve, B.9
Vasseur-Delannoy, V.10
Chikri, M.11
Charles, M.A.12
Clement, K.13
Lernmark, A.14
Froguel, P.15
-
131
-
-
23044493861
-
Variants of ENPP1 are associated with childhood and adult obesity and increase the risk of glucose intolerance and type 2 diabetes
-
Meyre, D., Bouatia-Naji, N., Tounian, A., Samson, C., Lecoeur, C., Vatin, V., Ghoussaini, M., Wachter, C., Hercberg, S., Charpentier, G., Patsch, W., Pattou, F. et al. (2005) Variants of ENPP1 are associated with childhood and adult obesity and increase the risk of glucose intolerance and type 2 diabetes. Nat. Genet. 37, 863-867.
-
(2005)
Nat. Genet
, vol.37
, pp. 863-867
-
-
Meyre, D.1
Bouatia-Naji, N.2
Tounian, A.3
Samson, C.4
Lecoeur, C.5
Vatin, V.6
Ghoussaini, M.7
Wachter, C.8
Hercberg, S.9
Charpentier, G.10
Patsch, W.11
Pattou, F.12
-
132
-
-
34848889315
-
Evaluation of genome-wide power of genetic association studies based on empirical data from the HapMap Project
-
Nannya, Y., Taura, K., Kurokawa, M. and Ogawa, S. (2007) Evaluation of genome-wide power of genetic association studies based on empirical data from the HapMap Project. Hum. Mol. Genet. 16, 3494-3505.
-
(2007)
Hum. Mol. Genet
, vol.16
, pp. 3494-3505
-
-
Nannya, Y.1
Taura, K.2
Kurokawa, M.3
Ogawa, S.4
-
133
-
-
84969213492
-
Genome-wide association study of 14 000 cases of seven common diseases and 3000 shared controls
-
Wellcome Trust Case Control Consortium
-
Wellcome Trust Case Control Consortium (2007) Genome-wide association study of 14 000 cases of seven common diseases and 3000 shared controls. Nature 447, 661-678.
-
(2007)
Nature
, vol.447
, pp. 661-678
-
-
-
134
-
-
34249828965
-
Avariant in CDKAL1influences insulin response and risk of type 2 diabetes
-
Steinthorsdottir, V., Thorleifsson, G., Reynisdottir, I., Benediktsson, R., Jonsdottir, T., Walters, G. B., Styrkarsdottir, U., Gretarsdottir, S., Emilsson, V., Ghosh, S., Baker, A., Snorradottir, S. et al. (2007)Avariant in CDKAL1influences insulin response and risk of type 2 diabetes. Nat. Genet. 39, 770-775.
-
(2007)
Nat. Genet
, vol.39
, pp. 770-775
-
-
Steinthorsdottir, V.1
Thorleifsson, G.2
Reynisdottir, I.3
Benediktsson, R.4
Jonsdottir, T.5
Walters, G.B.6
Styrkarsdottir, U.7
Gretarsdottir, S.8
Emilsson, V.9
Ghosh, S.10
Baker, A.11
Snorradottir, S.12
-
135
-
-
34249888775
-
Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels
-
Saxena, R., Voight, B. F., Lyssenko, V., Burtt, N. P., de Bakker, P. I., Chen, H., Roix, J. J., Kathiresan, S., Hirschhorn, J. N., Daly, M. J., Hughes, T. E., Groop, L. et al. (2007) Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science 316, 1331-1336.
-
(2007)
Science
, vol.316
, pp. 1331-1336
-
-
Saxena, R.1
Voight, B.F.2
Lyssenko, V.3
Burtt, N.P.4
de Bakker, P.I.5
Chen, H.6
Roix, J.J.7
Kathiresan, S.8
Hirschhorn, J.N.9
Daly, M.J.10
Hughes, T.E.11
Groop, L.12
-
136
-
-
34249885875
-
A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants
-
Scott, L. J., Mohlke, K. L., Bonnycastle, L. L., Willer, C. J., Li, Y., Duren, W. L., Erdos, M. R., Stringham, H. M., Chines, P. S., Jackson, A. U., Prokunina-Olsson, L., Ding, C. J. et al. (2007) A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. Science 316, 1341-1345.
-
(2007)
Science
, vol.316
, pp. 1341-1345
-
-
Scott, L.J.1
Mohlke, K.L.2
Bonnycastle, L.L.3
Willer, C.J.4
Li, Y.5
Duren, W.L.6
Erdos, M.R.7
Stringham, H.M.8
Chines, P.S.9
Jackson, A.U.10
Prokunina-Olsson, L.11
Ding, C.J.12
-
137
-
-
34547625955
-
Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits
-
Scuteri, A., Sanna, S., Chen, W. M., Uda, M., Albai, G., Strait, J., Najjar, S., Nagaraja, R., Orrffl, M., Usala, G., Dei, M., Lai, S. et al. (2007) Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits. PLoS Genet. 3, e115.
-
(2007)
PLoS Genet
, vol.3
-
-
Scuteri, A.1
Sanna, S.2
Chen, W.M.3
Uda, M.4
Albai, G.5
Strait, J.6
Najjar, S.7
Nagaraja, R.8
Orrffl, M.9
Usala, G.10
Dei, M.11
Lai, S.12
-
138
-
-
34248594090
-
A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity
-
Frayling, T. M., Timpson, N. J., Weedon, M. N., Zeggini, E., Freathy, R. M., Lindgren, C. M., Perry, J. R., Elliott, K. S., Lango, H., Rayner N W., Shields, B., Harries, L. W. et al. (2007) A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science 316, 889-894.
-
(2007)
Science
, vol.316
, pp. 889-894
-
-
Frayling, T.M.1
Timpson, N.J.2
Weedon, M.N.3
Zeggini, E.4
Freathy, R.M.5
Lindgren, C.M.6
Perry, J.R.7
Elliott, K.S.8
Lango, H.9
Rayner, N.W.10
Shields, B.11
Harries, L.W.12
-
139
-
-
34249777814
-
Variation in FTO contributes to childhood obesity and severe adult obesity
-
Dina, C., Meyre, D., Gallina, S., Durand, E., Körner, A., Jacobson, P., Carlsson, L. M., Kiess, W., Vatin, V., Lecoeur, C., Delplanque, J., Vaillant, E. et al. (2007) Variation in FTO contributes to childhood obesity and severe adult obesity. Nat. Genet. 39, 724-726.
-
(2007)
Nat. Genet
, vol.39
, pp. 724-726
-
-
Dina, C.1
Meyre, D.2
Gallina, S.3
Durand, E.4
Körner, A.5
Jacobson, P.6
Carlsson, L.M.7
Kiess, W.8
Vatin, V.9
Lecoeur, C.10
Delplanque, J.11
Vaillant, E.12
-
141
-
-
42449145150
-
-
World Health Organization. http://www.who.int./en/.
-
-
-
|