Cloning and characterization of AFX, the gene that fuses to MLL in acute leukemias with a t(X;11)(q13;q23)

Oncogene

Volumn 14, Issue 2, 1997, Pages 195-202

  Borkhardt, Arndt ^a   Repp, Reinald ^a   Haas, Oskar A ^b   Leis, Thomas ^a   Harbott, Jochen ^a   Kreuder, Joachim ^a   Hammermann, Jutta ^a   Henn, Traudl ^b   Lampert, Fritz ^a  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

^b ST ANNA CHILDREN S HOSPITAL   (Austria)

Author keywords

Acute leukemias; AFX gene; Forkhead domain; MLL rearrangement

Indexed keywords

HOMEODOMAIN PROTEIN;

ACUTE LEUKEMIA; ACUTE NONLYMPHOCYTIC LEUKEMIA; AMINO ACID SEQUENCE; ARTICLE; B LYMPHOCYTE; CHROMOSOME TRANSLOCATION 11; CHROMOSOME TRANSLOCATION 13; CHROMOSOME TRANSLOCATION 2; CHROMOSOME TRANSLOCATION X; EXON; GENE FUSION; GENETIC CONSERVATION; HOMEOBOX; HUMAN; HUMAN CELL; INTRON; MOLECULAR CLONING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DNA BINDING; RHABDOMYOSARCOMA; SEQUENCE HOMOLOGY; T LYMPHOCYTE;

EID: 0031031378     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1200814     Document Type: Article

References (46)

1. Baffa R, Negrini M, Schichman SA, Huebner K and Croce CM. (1995). Proc. Natl. Acad. Sci. USA, 92, 4922-4926.
2. Barletta C, Druck T, LaForgia S, Calabretta B, Drabkin H, Patterson D, Croce CM and Huebner K. (1991). Cancer Res., 51, 3821-3824.
3. Bernard OA, Mauchauffe M, Mecucci C, Van den Berghe H and Berger R. (1994). Oncogene, 9, 1039-1045.
4. Bernard OA and Berger R. (1995). Genes Chrom. Cancer, 13, 75-85.
5. Borkhardt A, Repp R, Haupt E, Brettreich S, Buchen U, Gossen R and Lampert F. (1994). Leukemia, 8, 549-553.
6. Chang C-P, Shen W-F, Rozenfeld S, Lawrence HJ, Largman C and Cleary ML. (1995). Genes Dev., 9, 663-674.
7. Chaplin T, Ayton P, Bernard OA, Saha V, Della Valle V, Hillion J, Gregorini A, Lillington D, Berger R and Young BD. (1995a). Blood, 85, 1435-1441.
8. Chaplin T, Bernard O, Beverloo HB, Saha V, Hagemeijer A, Berger R and Young BD. (1995b). Blood, 86, 2073-2076.
9. Cheng S, Fockler C, Barnes WM and Higuchi R. (1994). Proc. Natl. Acad. Sci. USA, 91, 5695-5699.
10. Chervinsky DS, Sait SNJ, Nowak NJ, Shows TB and Apian PD. (1995). Genes Chrom. Cancer, 14, 76-84.
11. Chomczynski P and Sacchi N. (1987). Anal. Biochem., 162, 156-159.
12. Corral J, Forster A, Thompson S, Lampert F, Kaneko Y, Slater R, van der Schoot CE, Ludwig WD, Pocock C, Cotter F and Rabbits TH. (1993). Proc. Natl. Acad. Sci. USA. 90, 8538-8542.
13. Deschamps J and Meijilink F. (1992). Crit. Rev. Oncogen., 3, 117-173.
14. Dreyling MH, Vignon C, Martinez-Climent JA, Zheng M, Mao J, Rowley JD and Bohlander SK. (1995). Blood, 86, suppl. 1, 430a.
15. Fredericks WJ, Galili N, Mukhopadhyay S, Rovera G, Bennicelli J, Barr FG and Rauscher III FJ. (1995). Mol. Cell. Biol., 15, 1522-1535.
16. Frohman MA, Dush MK and Martin GR. (1988). Proc. Natl. Acad. Sci. USA, 85, 8998-9002.
17. Gehring WJ, Qian Q, Billeter M, Furukubo-Tokunaga K, Schier AF, Resendez-Perez D, Affolter M, Otting G and Wüthrich K. (1994). Cell, 78, 211-223.
18. Gu Y, Nakamura T, Alder H, Prasad R, Canaani O, Cimino G, Croce CM and Canaani E. (1992). Cell, 71, 701-708.
19. Gu Y, Alder H, Nakamura T, Schichman SA, Prasad R, Canaani O, Saito H, Croce CM and Canaani E. (1994). Cancer Res., 54, 2327-2330.
20. Hromas R, Moore J, Johnston T, Socha C and Klemsz M. (1993). Blood, 81, 2854-2859.
21. Hromas R and Costa R. (1995). Crit. Rev. Oncol./Hematol., 20, 129-140.
22. Introna M, Luchetti M, Castellano M, Arsura M and Golay J. (1994). Seminars in Cancer Biology, 5, 113-124.
23. Kamps MP, Murre CM, Sun X-H and Baltimore D. (1990). Cell, 60, 547-555.
24. Karpas A, Hayhoe FJG, Greenberger S, Barker CR, Cawley JC, Louenthal RM and Moloney WC. (1977). Leuk. Res., 1, 35-49.
25. Kozak M. (1991). J. Biol. Chem., 266, 19867-19870.
26. Li C, Lusis AJ, Sparkes R, Tran SM and Gaynor R. (1992). Genomics, 13, 658-664.
27. Li J and Vogt PK. (1993). Proc. Natl. Acad. Sci. USA, 90, 4490-4494.
28. Lin D, Fiscella M, O'Connor PM, Jackman J, Chen M, Luo LL, Sala A, Travali S, Appella E and Mercer WE. (1994). Proc. Natl. Acad. Sci. USA, 91, 10079-10083.
29. McCabe NR, Burnett RC, Gill HJ, Thirman MJ, Mbangkollo D, Kipiniak M, Van Melle E, Ziemin-van der Poel S, Rowley JD and Diaz MO. (1992). Proc. Nutl. Acad. Sci. USA, 89, 11794-11798.
30. Nacheva E, Fischer P, Haas O, Manolova Y, Manolov G and Levan A. (1982). Hereditas, 97, 273-288.
31. Nakamura T, Alder H, Gu Y, Prasad R, Canaani O, Kamada N, Gale RP, Lange B, Crist WM, Nowell PC, Croce CM and Canaani E. (1993). Proc. Natl. Acad. Sci. USA 90, 4631-4635.
32. Nakamura T, Largaespada DA, Shaughnessy Jr JD, Jenkins NA and Copeland NG. (1996). Nature Genetics, 12, 149-153.
33. Parry P, Wei Y and Evans G. (1994). Genes Chrom. Cancer, 11, 79-84.
34. Phelan ML, Rambaldi I and Featherstone MS. (1995). Mol. Cell. Biol., 15, 3989-3997.
35. Prasad R, Leshkowitz D, Gu Y, Alder H, Nakamura T, Saito H, Huebner K, Berger R, Croce CM and Canaani E. (1994). Proc. Natl. Acad. Sci. USA, 91, 8107-8111.
36. Rabbitts TH. (1994). Nature, 372, 143-149.
37. Raschella G, Negroni A, Sala A, Pucci S, Romeo A and Calabretta B. (1995). J. Biol. Chem., 270, 8540-8545.
38. Rienitz A, Grenningloh G, Hermans-Borgmeyer I, Kirsch J, Littauer UZ, Prior P, Gundelfinger ED, Schmitt B and Betz H. (1989). EMJO J., 8, 2879-2888.
39. Rowley JD. (1992). Genes Chrom. Cancer, 5, 264-266.
40. Rowley JD. (1993). Seminars in Cancer Biology, 4, 377-385.
41. Sambrock J, Fritsch EF and Maniatis T. (1989). Molecular cloning: A laboratory manual, Cold Spring Harbor: Cold Spring Harbor University Press, 1989.
42. Sanger F, Nicklen S and Coulson AR. (1977) Proc. Natl. Acad. Sd. USA., 74, 5463-5467.
43. Schichman ST, Caligiuri MA, Gu Y, Strout MP, Canaani E, Bloomfield CD and Croce CM. (1994). Proc. Natl. Acad. Sci. USA, 91, 6236-6239.
44. Shilatifard A, Lane WS, Jackson KW, Conaway RC and Conaway JW. (1996). Science, 271, 1873-1876.
45. Theill LE, Castrillo JL, Wu D and Karin M. (1989). Nature, 342, 945-948.
46. Tkachuk DC, Kohler S and Cleary ML. (1992). Cell, 71, 691-700.